Contact Information
Call us at: (614) 355-5907
Email Ying-Chen Claire Hou, PhD
Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)
Learn more about Ying-Chen Claire Hou
Biography
Ying-Chen Claire Hou, PhD, is a director within the Institute for Genomic Medicine at Nationwide Children’s Hospital. She is an assistant professor-clinical within the Departments of Pathology and Pediatrics at The Ohio State University. Claire received her doctoral degree in Genetics from the University of British Columbia where she performed functional screening tests to understand the crosstalk between apoptosis and autophagy. Claire completed her post-doctoral training at the Sanford Burnham Prebys Medical Discovery institute where she performed genome-wide RNAi screens to understand endoplasmic reticulum stress and delineate its association with neurodegenerative diseases. Claire completed her Laboratory Genomics and Genetics (LGG) fellowship at Washington University School of Medicine in St. Louis where she develops strong interests in cancer cytogenetics and cancer genomics. Prior to her LGG fellowship, Claire has worked at industry positions where she was involved in the development and validation of various genomic tests, including pharmacogenomics, inherited cancer, and whole genome sequencing. During her industry positions, she was also actively involved in research activities. She published two papers on a precision medicine study that integrated whole-genome sequencing, comprehensive metabolomics, and advanced imaging to understand the value and clinical impact of surveying genome-wide disease-causing genes and variants in presumed healthy adults. She also gave platform presentations for these works at the American Society of Human Genetics annual meetings.
Awards, Honors & Organizations
Poster Award, ACMG Clinical Genetics Meeting, 2022 Fellowship, American Lung Association, 2012 Seed Grant, San Diego Center for System Biology, 2011 Postdoctoral Fellowship Award, TRDRP Member, American College of Medical Genetics, 2018 - Present Member, American Society of Human Genetics, 2017 - Present
Research
Publications
Hou YC, Neidich JA, Duncavage EJ, Spencer DH, Schroeder MC. Clinical whole-genome sequencing in cancer diagnosis. Hum Mutat. 2022 Nov; 43: 1519-1530.
Hou YC, Evenson MJ, Corliss MM, Mahapatra L, Aldawood A, Carpentieri DF, Chamlin SL, Kulungowski AM, Madan-Khetarpal S, Sebastian J, Pet MA, Coughlin CC, Willing MC, Pearson GD, Setty BA, El-Haffaf Z, Cottrell CE, Parikh BA, Krysiak K, Schroeder MC, Heusel JW, Neidich JA, Cao Y. A Comparative Analysis of RAS Variants in Patients with Disorders of Somatic Mosaicism. Genet Med. 2022 Nov 29;
Starosta RT, Hou YC, Leestma K, Singh P, Viehl L, Manwaring L, Granadillo JL, Schroeder MC, Colombo JN, Whitehead H, Dickson PI, Hulbert ML, Nguyen HT. Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations. Front Pediatr. 2022; 10: 944178.
Sams EI, Ng JK, Tate V, Claire Hou YC, Cao Y, Antonacci-Fulton L, Belhassan K, Neidich J, Mitra RD, Cole FS, Dickson P, Milbrandt J, Turner TN. From karyotypes to precision genomics in 9p deletion and duplication syndromes. HGG Adv. 2022 Jan 13; 3: 100081.
Hou YC, Yu HC, Martin R, Cirulli ET, Schenker-Ahmed NM, Hicks M, Cohen IV, Jönsson TJ, Heister R, Napier L, Swisher CL, Dominguez S, Tang H, Li W, Perkins BA, Barea J, Rybak C, Smith E, Duchicela K, Doney M, Brar P, Hernandez N, Kirkness EF, Kahn AM, Venter JC, Karow DS, Caskey CT. Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging. Proc Natl Acad Sci U S A. 2020 Feb 11; 117: 3053-3062.
Perkins BA, Caskey CT, Brar P, Dec E, Karow DS, Kahn AM, Hou YC, Shah N, Boeldt D, Coughlin E, Hands G, Lavrenko V, Yu J, Procko A, Appis J, Dale AM, Guo L, Jönsson TJ, Wittmann BM, Bartha I, Ramakrishnan S, Bernal A, Brewer JB, Brewerton S, Biggs WH, Turpaz Y, Venter JC. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 Apr 3; 115: 3686-3691.
Shah N, Hou YC, Yu HC, Sainger R, Caskey CT, Venter JC, Telenti A. Identification of Misclassified ClinVar Variants via Disease Population Prevalence. Am J Hum Genet. 2018 Apr 5; 102: 609-619.
Tang H, Kirkness EF, Lippert C, Biggs WH, Fabani M, Guzman E, Ramakrishnan S, Lavrenko V, Kakaradov B, Hou C, Hicks B, Heckerman D, Och FJ, Caskey CT, Venter JC, Telenti A. Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes. Am J Hum Genet. 2017 Nov 2; 101: 700-715.
View More Publications
Education
Fellowship
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Date Completed: 06/30/2022
Graduate School
The University of British Columbia
Date Completed: 07/01/2009
Professional Experience
2015 - 2020 Human Longevity Inc., Principal Scientist, Clinical Genetics2014 - 2015 Pathway Genomics, Genetics Scientist R&D
Contact Information
Institute for Genomic Medicine
Call us at: (614) 355-5907
Email Ying ChenClaire Hou
575 Children’s CrossroadColumbus, OH 43215 (map)
Contact Information
Call us at: (614) 355-5907
Email Ying-Chen Claire Hou, PhD
Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)
Learn more about Ying-Chen Claire Hou
Biography
Ying-Chen Claire Hou, PhD, is a director within the Institute for Genomic Medicine at Nationwide Children’s Hospital. She is an assistant professor-clinical within the Departments of Pathology and Pediatrics at The Ohio State University. Claire received her doctoral degree in Genetics from the University of British Columbia where she performed functional screening tests to understand the crosstalk between apoptosis and autophagy. Claire completed her post-doctoral training at the Sanford Burnham Prebys Medical Discovery institute where she performed genome-wide RNAi screens to understand endoplasmic reticulum stress and delineate its association with neurodegenerative diseases. Claire completed her Laboratory Genomics and Genetics (LGG) fellowship at Washington University School of Medicine in St. Louis where she develops strong interests in cancer cytogenetics and cancer genomics. Prior to her LGG fellowship, Claire has worked at industry positions where she was involved in the development and validation of various genomic tests, including pharmacogenomics, inherited cancer, and whole genome sequencing. During her industry positions, she was also actively involved in research activities. She published two papers on a precision medicine study that integrated whole-genome sequencing, comprehensive metabolomics, and advanced imaging to understand the value and clinical impact of surveying genome-wide disease-causing genes and variants in presumed healthy adults. She also gave platform presentations for these works at the American Society of Human Genetics annual meetings.
Awards, Honors & Organizations
Poster Award, ACMG Clinical Genetics Meeting, 2022 Fellowship, American Lung Association, 2012 Seed Grant, San Diego Center for System Biology, 2011 Postdoctoral Fellowship Award, TRDRP Member, American College of Medical Genetics, 2018 - Present Member, American Society of Human Genetics, 2017 - Present
Research
Publications
Hou YC, Neidich JA, Duncavage EJ, Spencer DH, Schroeder MC. Clinical whole-genome sequencing in cancer diagnosis. Hum Mutat. 2022 Nov; 43: 1519-1530.
Hou YC, Evenson MJ, Corliss MM, Mahapatra L, Aldawood A, Carpentieri DF, Chamlin SL, Kulungowski AM, Madan-Khetarpal S, Sebastian J, Pet MA, Coughlin CC, Willing MC, Pearson GD, Setty BA, El-Haffaf Z, Cottrell CE, Parikh BA, Krysiak K, Schroeder MC, Heusel JW, Neidich JA, Cao Y. A Comparative Analysis of RAS Variants in Patients with Disorders of Somatic Mosaicism. Genet Med. 2022 Nov 29;
Starosta RT, Hou YC, Leestma K, Singh P, Viehl L, Manwaring L, Granadillo JL, Schroeder MC, Colombo JN, Whitehead H, Dickson PI, Hulbert ML, Nguyen HT. Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations. Front Pediatr. 2022; 10: 944178.
Sams EI, Ng JK, Tate V, Claire Hou YC, Cao Y, Antonacci-Fulton L, Belhassan K, Neidich J, Mitra RD, Cole FS, Dickson P, Milbrandt J, Turner TN. From karyotypes to precision genomics in 9p deletion and duplication syndromes. HGG Adv. 2022 Jan 13; 3: 100081.
Hou YC, Yu HC, Martin R, Cirulli ET, Schenker-Ahmed NM, Hicks M, Cohen IV, Jönsson TJ, Heister R, Napier L, Swisher CL, Dominguez S, Tang H, Li W, Perkins BA, Barea J, Rybak C, Smith E, Duchicela K, Doney M, Brar P, Hernandez N, Kirkness EF, Kahn AM, Venter JC, Karow DS, Caskey CT. Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging. Proc Natl Acad Sci U S A. 2020 Feb 11; 117: 3053-3062.
Perkins BA, Caskey CT, Brar P, Dec E, Karow DS, Kahn AM, Hou YC, Shah N, Boeldt D, Coughlin E, Hands G, Lavrenko V, Yu J, Procko A, Appis J, Dale AM, Guo L, Jönsson TJ, Wittmann BM, Bartha I, Ramakrishnan S, Bernal A, Brewer JB, Brewerton S, Biggs WH, Turpaz Y, Venter JC. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 Apr 3; 115: 3686-3691.
Shah N, Hou YC, Yu HC, Sainger R, Caskey CT, Venter JC, Telenti A. Identification of Misclassified ClinVar Variants via Disease Population Prevalence. Am J Hum Genet. 2018 Apr 5; 102: 609-619.
Tang H, Kirkness EF, Lippert C, Biggs WH, Fabani M, Guzman E, Ramakrishnan S, Lavrenko V, Kakaradov B, Hou C, Hicks B, Heckerman D, Och FJ, Caskey CT, Venter JC, Telenti A. Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes. Am J Hum Genet. 2017 Nov 2; 101: 700-715.
View More Publications
Education
Fellowship
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Date Completed: 06/30/2022
Graduate School
The University of British Columbia
Date Completed: 07/01/2009
Professional Experience
2015 - 2020 Human Longevity Inc., Principal Scientist, Clinical Genetics2014 - 2015 Pathway Genomics, Genetics Scientist R&D
Contact Information
Institute for Genomic Medicine
Call us at: (614) 355-5907
Email Ying ChenClaire Hou
575 Children’s CrossroadColumbus, OH 43215 (map)
Contact Information
Call us at: (614) 355-5907
Email Ying-Chen Claire Hou, PhD
Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)
Learn more about Ying-Chen Claire Hou
Contact Information
- Call us at:
- (614) 355-5907
- Email Ying-Chen Claire Hou, PhD
- Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)
Learn more about Ying-Chen Claire Hou
Biography
Ying-Chen Claire Hou, PhD, is a director within the Institute for Genomic Medicine at Nationwide Children’s Hospital. She is an assistant professor-clinical within the Departments of Pathology and Pediatrics at The Ohio State University. Claire received her doctoral degree in Genetics from the University of British Columbia where she performed functional screening tests to understand the crosstalk between apoptosis and autophagy. Claire completed her post-doctoral training at the Sanford Burnham Prebys Medical Discovery institute where she performed genome-wide RNAi screens to understand endoplasmic reticulum stress and delineate its association with neurodegenerative diseases. Claire completed her Laboratory Genomics and Genetics (LGG) fellowship at Washington University School of Medicine in St. Louis where she develops strong interests in cancer cytogenetics and cancer genomics. Prior to her LGG fellowship, Claire has worked at industry positions where she was involved in the development and validation of various genomic tests, including pharmacogenomics, inherited cancer, and whole genome sequencing. During her industry positions, she was also actively involved in research activities. She published two papers on a precision medicine study that integrated whole-genome sequencing, comprehensive metabolomics, and advanced imaging to understand the value and clinical impact of surveying genome-wide disease-causing genes and variants in presumed healthy adults. She also gave platform presentations for these works at the American Society of Human Genetics annual meetings.
Biography
Ying-Chen Claire Hou, PhD, is a director within the Institute for Genomic Medicine at Nationwide Children’s Hospital. She is an assistant professor-clinical within the Departments of Pathology and Pediatrics at The Ohio State University. Claire received her doctoral degree in Genetics from the University of British Columbia where she performed functional screening tests to understand the crosstalk between apoptosis and autophagy. Claire completed her post-doctoral training at the Sanford Burnham Prebys Medical Discovery institute where she performed genome-wide RNAi screens to understand endoplasmic reticulum stress and delineate its association with neurodegenerative diseases. Claire completed her Laboratory Genomics and Genetics (LGG) fellowship at Washington University School of Medicine in St. Louis where she develops strong interests in cancer cytogenetics and cancer genomics. Prior to her LGG fellowship, Claire has worked at industry positions where she was involved in the development and validation of various genomic tests, including pharmacogenomics, inherited cancer, and whole genome sequencing. During her industry positions, she was also actively involved in research activities. She published two papers on a precision medicine study that integrated whole-genome sequencing, comprehensive metabolomics, and advanced imaging to understand the value and clinical impact of surveying genome-wide disease-causing genes and variants in presumed healthy adults. She also gave platform presentations for these works at the American Society of Human Genetics annual meetings.
Biography
Ying-Chen Claire Hou, PhD, is a director within the Institute for Genomic Medicine at Nationwide Children’s Hospital. She is an assistant professor-clinical within the Departments of Pathology and Pediatrics at The Ohio State University. Claire received her doctoral degree in Genetics from the University of British Columbia where she performed functional screening tests to understand the crosstalk between apoptosis and autophagy. Claire completed her post-doctoral training at the Sanford Burnham Prebys Medical Discovery institute where she performed genome-wide RNAi screens to understand endoplasmic reticulum stress and delineate its association with neurodegenerative diseases. Claire completed her Laboratory Genomics and Genetics (LGG) fellowship at Washington University School of Medicine in St. Louis where she develops strong interests in cancer cytogenetics and cancer genomics. Prior to her LGG fellowship, Claire has worked at industry positions where she was involved in the development and validation of various genomic tests, including pharmacogenomics, inherited cancer, and whole genome sequencing. During her industry positions, she was also actively involved in research activities. She published two papers on a precision medicine study that integrated whole-genome sequencing, comprehensive metabolomics, and advanced imaging to understand the value and clinical impact of surveying genome-wide disease-causing genes and variants in presumed healthy adults. She also gave platform presentations for these works at the American Society of Human Genetics annual meetings.
Ying-Chen Claire Hou, PhD, is a director within the Institute for Genomic Medicine at Nationwide Children’s Hospital. She is an assistant professor-clinical within the Departments of Pathology and Pediatrics at The Ohio State University. Claire received her doctoral degree in Genetics from the University of British Columbia where she performed functional screening tests to understand the crosstalk between apoptosis and autophagy. Claire completed her post-doctoral training at the Sanford Burnham Prebys Medical Discovery institute where she performed genome-wide RNAi screens to understand endoplasmic reticulum stress and delineate its association with neurodegenerative diseases. Claire completed her Laboratory Genomics and Genetics (LGG) fellowship at Washington University School of Medicine in St. Louis where she develops strong interests in cancer cytogenetics and cancer genomics. Prior to her LGG fellowship, Claire has worked at industry positions where she was involved in the development and validation of various genomic tests, including pharmacogenomics, inherited cancer, and whole genome sequencing. During her industry positions, she was also actively involved in research activities. She published two papers on a precision medicine study that integrated whole-genome sequencing, comprehensive metabolomics, and advanced imaging to understand the value and clinical impact of surveying genome-wide disease-causing genes and variants in presumed healthy adults. She also gave platform presentations for these works at the American Society of Human Genetics annual meetings.
Ying-Chen Claire Hou, PhD, is a director within the Institute for Genomic Medicine at Nationwide Children’s Hospital. She is an assistant professor-clinical within the Departments of Pathology and Pediatrics at The Ohio State University. Claire received her doctoral degree in Genetics from the University of British Columbia where she performed functional screening tests to understand the crosstalk between apoptosis and autophagy. Claire completed her post-doctoral training at the Sanford Burnham Prebys Medical Discovery institute where she performed genome-wide RNAi screens to understand endoplasmic reticulum stress and delineate its association with neurodegenerative diseases. Claire completed her Laboratory Genomics and Genetics (LGG) fellowship at Washington University School of Medicine in St. Louis where she develops strong interests in cancer cytogenetics and cancer genomics.
Prior to her LGG fellowship, Claire has worked at industry positions where she was involved in the development and validation of various genomic tests, including pharmacogenomics, inherited cancer, and whole genome sequencing. During her industry positions, she was also actively involved in research activities. She published two papers on a precision medicine study that integrated whole-genome sequencing, comprehensive metabolomics, and advanced imaging to understand the value and clinical impact of surveying genome-wide disease-causing genes and variants in presumed healthy adults. She also gave platform presentations for these works at the American Society of Human Genetics annual meetings.
Awards, Honors & Organizations
Poster Award, ACMG Clinical Genetics Meeting, 2022 Fellowship, American Lung Association, 2012 Seed Grant, San Diego Center for System Biology, 2011 Postdoctoral Fellowship Award, TRDRP Member, American College of Medical Genetics, 2018 - Present Member, American Society of Human Genetics, 2017 - Present
Awards, Honors & Organizations
Poster Award, ACMG Clinical Genetics Meeting, 2022 Fellowship, American Lung Association, 2012 Seed Grant, San Diego Center for System Biology, 2011 Postdoctoral Fellowship Award, TRDRP Member, American College of Medical Genetics, 2018 - Present Member, American Society of Human Genetics, 2017 - Present
Awards, Honors & Organizations
Poster Award, ACMG Clinical Genetics Meeting, 2022 Fellowship, American Lung Association, 2012 Seed Grant, San Diego Center for System Biology, 2011 Postdoctoral Fellowship Award, TRDRP Member, American College of Medical Genetics, 2018 - Present Member, American Society of Human Genetics, 2017 - Present
Poster Award, ACMG Clinical Genetics Meeting, 2022 Fellowship, American Lung Association, 2012 Seed Grant, San Diego Center for System Biology, 2011 Postdoctoral Fellowship Award, TRDRP Member, American College of Medical Genetics, 2018 - Present Member, American Society of Human Genetics, 2017 - Present
- Poster Award, ACMG Clinical Genetics Meeting, 2022
- Fellowship, American Lung Association, 2012
- Seed Grant, San Diego Center for System Biology, 2011
- Postdoctoral Fellowship Award, TRDRP
- Member, American College of Medical Genetics, 2018 - Present
- Member, American Society of Human Genetics, 2017 - Present
Research
Publications
Hou YC, Neidich JA, Duncavage EJ, Spencer DH, Schroeder MC. Clinical whole-genome sequencing in cancer diagnosis. Hum Mutat. 2022 Nov; 43: 1519-1530.
Hou YC, Evenson MJ, Corliss MM, Mahapatra L, Aldawood A, Carpentieri DF, Chamlin SL, Kulungowski AM, Madan-Khetarpal S, Sebastian J, Pet MA, Coughlin CC, Willing MC, Pearson GD, Setty BA, El-Haffaf Z, Cottrell CE, Parikh BA, Krysiak K, Schroeder MC, Heusel JW, Neidich JA, Cao Y. A Comparative Analysis of RAS Variants in Patients with Disorders of Somatic Mosaicism. Genet Med. 2022 Nov 29;
Starosta RT, Hou YC, Leestma K, Singh P, Viehl L, Manwaring L, Granadillo JL, Schroeder MC, Colombo JN, Whitehead H, Dickson PI, Hulbert ML, Nguyen HT. Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations. Front Pediatr. 2022; 10: 944178.
Sams EI, Ng JK, Tate V, Claire Hou YC, Cao Y, Antonacci-Fulton L, Belhassan K, Neidich J, Mitra RD, Cole FS, Dickson P, Milbrandt J, Turner TN. From karyotypes to precision genomics in 9p deletion and duplication syndromes. HGG Adv. 2022 Jan 13; 3: 100081.
Hou YC, Yu HC, Martin R, Cirulli ET, Schenker-Ahmed NM, Hicks M, Cohen IV, Jönsson TJ, Heister R, Napier L, Swisher CL, Dominguez S, Tang H, Li W, Perkins BA, Barea J, Rybak C, Smith E, Duchicela K, Doney M, Brar P, Hernandez N, Kirkness EF, Kahn AM, Venter JC, Karow DS, Caskey CT. Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging. Proc Natl Acad Sci U S A. 2020 Feb 11; 117: 3053-3062.
Perkins BA, Caskey CT, Brar P, Dec E, Karow DS, Kahn AM, Hou YC, Shah N, Boeldt D, Coughlin E, Hands G, Lavrenko V, Yu J, Procko A, Appis J, Dale AM, Guo L, Jönsson TJ, Wittmann BM, Bartha I, Ramakrishnan S, Bernal A, Brewer JB, Brewerton S, Biggs WH, Turpaz Y, Venter JC. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 Apr 3; 115: 3686-3691.
Shah N, Hou YC, Yu HC, Sainger R, Caskey CT, Venter JC, Telenti A. Identification of Misclassified ClinVar Variants via Disease Population Prevalence. Am J Hum Genet. 2018 Apr 5; 102: 609-619.
Tang H, Kirkness EF, Lippert C, Biggs WH, Fabani M, Guzman E, Ramakrishnan S, Lavrenko V, Kakaradov B, Hou C, Hicks B, Heckerman D, Och FJ, Caskey CT, Venter JC, Telenti A. Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes. Am J Hum Genet. 2017 Nov 2; 101: 700-715.
View More Publications
Research
Publications
Hou YC, Neidich JA, Duncavage EJ, Spencer DH, Schroeder MC. Clinical whole-genome sequencing in cancer diagnosis. Hum Mutat. 2022 Nov; 43: 1519-1530.
Hou YC, Evenson MJ, Corliss MM, Mahapatra L, Aldawood A, Carpentieri DF, Chamlin SL, Kulungowski AM, Madan-Khetarpal S, Sebastian J, Pet MA, Coughlin CC, Willing MC, Pearson GD, Setty BA, El-Haffaf Z, Cottrell CE, Parikh BA, Krysiak K, Schroeder MC, Heusel JW, Neidich JA, Cao Y. A Comparative Analysis of RAS Variants in Patients with Disorders of Somatic Mosaicism. Genet Med. 2022 Nov 29;
Starosta RT, Hou YC, Leestma K, Singh P, Viehl L, Manwaring L, Granadillo JL, Schroeder MC, Colombo JN, Whitehead H, Dickson PI, Hulbert ML, Nguyen HT. Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations. Front Pediatr. 2022; 10: 944178.
Sams EI, Ng JK, Tate V, Claire Hou YC, Cao Y, Antonacci-Fulton L, Belhassan K, Neidich J, Mitra RD, Cole FS, Dickson P, Milbrandt J, Turner TN. From karyotypes to precision genomics in 9p deletion and duplication syndromes. HGG Adv. 2022 Jan 13; 3: 100081.
Hou YC, Yu HC, Martin R, Cirulli ET, Schenker-Ahmed NM, Hicks M, Cohen IV, Jönsson TJ, Heister R, Napier L, Swisher CL, Dominguez S, Tang H, Li W, Perkins BA, Barea J, Rybak C, Smith E, Duchicela K, Doney M, Brar P, Hernandez N, Kirkness EF, Kahn AM, Venter JC, Karow DS, Caskey CT. Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging. Proc Natl Acad Sci U S A. 2020 Feb 11; 117: 3053-3062.
Perkins BA, Caskey CT, Brar P, Dec E, Karow DS, Kahn AM, Hou YC, Shah N, Boeldt D, Coughlin E, Hands G, Lavrenko V, Yu J, Procko A, Appis J, Dale AM, Guo L, Jönsson TJ, Wittmann BM, Bartha I, Ramakrishnan S, Bernal A, Brewer JB, Brewerton S, Biggs WH, Turpaz Y, Venter JC. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 Apr 3; 115: 3686-3691.
Shah N, Hou YC, Yu HC, Sainger R, Caskey CT, Venter JC, Telenti A. Identification of Misclassified ClinVar Variants via Disease Population Prevalence. Am J Hum Genet. 2018 Apr 5; 102: 609-619.
Tang H, Kirkness EF, Lippert C, Biggs WH, Fabani M, Guzman E, Ramakrishnan S, Lavrenko V, Kakaradov B, Hou C, Hicks B, Heckerman D, Och FJ, Caskey CT, Venter JC, Telenti A. Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes. Am J Hum Genet. 2017 Nov 2; 101: 700-715.
View More Publications
Research
Publications
Hou YC, Neidich JA, Duncavage EJ, Spencer DH, Schroeder MC. Clinical whole-genome sequencing in cancer diagnosis. Hum Mutat. 2022 Nov; 43: 1519-1530.
Hou YC, Evenson MJ, Corliss MM, Mahapatra L, Aldawood A, Carpentieri DF, Chamlin SL, Kulungowski AM, Madan-Khetarpal S, Sebastian J, Pet MA, Coughlin CC, Willing MC, Pearson GD, Setty BA, El-Haffaf Z, Cottrell CE, Parikh BA, Krysiak K, Schroeder MC, Heusel JW, Neidich JA, Cao Y. A Comparative Analysis of RAS Variants in Patients with Disorders of Somatic Mosaicism. Genet Med. 2022 Nov 29;
Starosta RT, Hou YC, Leestma K, Singh P, Viehl L, Manwaring L, Granadillo JL, Schroeder MC, Colombo JN, Whitehead H, Dickson PI, Hulbert ML, Nguyen HT. Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations. Front Pediatr. 2022; 10: 944178.
Sams EI, Ng JK, Tate V, Claire Hou YC, Cao Y, Antonacci-Fulton L, Belhassan K, Neidich J, Mitra RD, Cole FS, Dickson P, Milbrandt J, Turner TN. From karyotypes to precision genomics in 9p deletion and duplication syndromes. HGG Adv. 2022 Jan 13; 3: 100081.
Hou YC, Yu HC, Martin R, Cirulli ET, Schenker-Ahmed NM, Hicks M, Cohen IV, Jönsson TJ, Heister R, Napier L, Swisher CL, Dominguez S, Tang H, Li W, Perkins BA, Barea J, Rybak C, Smith E, Duchicela K, Doney M, Brar P, Hernandez N, Kirkness EF, Kahn AM, Venter JC, Karow DS, Caskey CT. Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging. Proc Natl Acad Sci U S A. 2020 Feb 11; 117: 3053-3062.
Perkins BA, Caskey CT, Brar P, Dec E, Karow DS, Kahn AM, Hou YC, Shah N, Boeldt D, Coughlin E, Hands G, Lavrenko V, Yu J, Procko A, Appis J, Dale AM, Guo L, Jönsson TJ, Wittmann BM, Bartha I, Ramakrishnan S, Bernal A, Brewer JB, Brewerton S, Biggs WH, Turpaz Y, Venter JC. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 Apr 3; 115: 3686-3691.
Shah N, Hou YC, Yu HC, Sainger R, Caskey CT, Venter JC, Telenti A. Identification of Misclassified ClinVar Variants via Disease Population Prevalence. Am J Hum Genet. 2018 Apr 5; 102: 609-619.
Tang H, Kirkness EF, Lippert C, Biggs WH, Fabani M, Guzman E, Ramakrishnan S, Lavrenko V, Kakaradov B, Hou C, Hicks B, Heckerman D, Och FJ, Caskey CT, Venter JC, Telenti A. Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes. Am J Hum Genet. 2017 Nov 2; 101: 700-715.
View More Publications
Publications
Hou YC, Neidich JA, Duncavage EJ, Spencer DH, Schroeder MC. Clinical whole-genome sequencing in cancer diagnosis. Hum Mutat. 2022 Nov; 43: 1519-1530.
Hou YC, Evenson MJ, Corliss MM, Mahapatra L, Aldawood A, Carpentieri DF, Chamlin SL, Kulungowski AM, Madan-Khetarpal S, Sebastian J, Pet MA, Coughlin CC, Willing MC, Pearson GD, Setty BA, El-Haffaf Z, Cottrell CE, Parikh BA, Krysiak K, Schroeder MC, Heusel JW, Neidich JA, Cao Y. A Comparative Analysis of RAS Variants in Patients with Disorders of Somatic Mosaicism. Genet Med. 2022 Nov 29;
Starosta RT, Hou YC, Leestma K, Singh P, Viehl L, Manwaring L, Granadillo JL, Schroeder MC, Colombo JN, Whitehead H, Dickson PI, Hulbert ML, Nguyen HT. Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations. Front Pediatr. 2022; 10: 944178.
Sams EI, Ng JK, Tate V, Claire Hou YC, Cao Y, Antonacci-Fulton L, Belhassan K, Neidich J, Mitra RD, Cole FS, Dickson P, Milbrandt J, Turner TN. From karyotypes to precision genomics in 9p deletion and duplication syndromes. HGG Adv. 2022 Jan 13; 3: 100081.
Hou YC, Yu HC, Martin R, Cirulli ET, Schenker-Ahmed NM, Hicks M, Cohen IV, Jönsson TJ, Heister R, Napier L, Swisher CL, Dominguez S, Tang H, Li W, Perkins BA, Barea J, Rybak C, Smith E, Duchicela K, Doney M, Brar P, Hernandez N, Kirkness EF, Kahn AM, Venter JC, Karow DS, Caskey CT. Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging. Proc Natl Acad Sci U S A. 2020 Feb 11; 117: 3053-3062.
Perkins BA, Caskey CT, Brar P, Dec E, Karow DS, Kahn AM, Hou YC, Shah N, Boeldt D, Coughlin E, Hands G, Lavrenko V, Yu J, Procko A, Appis J, Dale AM, Guo L, Jönsson TJ, Wittmann BM, Bartha I, Ramakrishnan S, Bernal A, Brewer JB, Brewerton S, Biggs WH, Turpaz Y, Venter JC. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 Apr 3; 115: 3686-3691.
Shah N, Hou YC, Yu HC, Sainger R, Caskey CT, Venter JC, Telenti A. Identification of Misclassified ClinVar Variants via Disease Population Prevalence. Am J Hum Genet. 2018 Apr 5; 102: 609-619.
Tang H, Kirkness EF, Lippert C, Biggs WH, Fabani M, Guzman E, Ramakrishnan S, Lavrenko V, Kakaradov B, Hou C, Hicks B, Heckerman D, Och FJ, Caskey CT, Venter JC, Telenti A. Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes. Am J Hum Genet. 2017 Nov 2; 101: 700-715.
View More Publications
Hou YC, Neidich JA, Duncavage EJ, Spencer DH, Schroeder MC. Clinical whole-genome sequencing in cancer diagnosis. Hum Mutat. 2022 Nov; 43: 1519-1530.
Hou YC, Evenson MJ, Corliss MM, Mahapatra L, Aldawood A, Carpentieri DF, Chamlin SL, Kulungowski AM, Madan-Khetarpal S, Sebastian J, Pet MA, Coughlin CC, Willing MC, Pearson GD, Setty BA, El-Haffaf Z, Cottrell CE, Parikh BA, Krysiak K, Schroeder MC, Heusel JW, Neidich JA, Cao Y. A Comparative Analysis of RAS Variants in Patients with Disorders of Somatic Mosaicism. Genet Med. 2022 Nov 29;
Starosta RT, Hou YC, Leestma K, Singh P, Viehl L, Manwaring L, Granadillo JL, Schroeder MC, Colombo JN, Whitehead H, Dickson PI, Hulbert ML, Nguyen HT. Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations. Front Pediatr. 2022; 10: 944178.
Sams EI, Ng JK, Tate V, Claire Hou YC, Cao Y, Antonacci-Fulton L, Belhassan K, Neidich J, Mitra RD, Cole FS, Dickson P, Milbrandt J, Turner TN. From karyotypes to precision genomics in 9p deletion and duplication syndromes. HGG Adv. 2022 Jan 13; 3: 100081.
Hou YC, Yu HC, Martin R, Cirulli ET, Schenker-Ahmed NM, Hicks M, Cohen IV, Jönsson TJ, Heister R, Napier L, Swisher CL, Dominguez S, Tang H, Li W, Perkins BA, Barea J, Rybak C, Smith E, Duchicela K, Doney M, Brar P, Hernandez N, Kirkness EF, Kahn AM, Venter JC, Karow DS, Caskey CT. Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging. Proc Natl Acad Sci U S A. 2020 Feb 11; 117: 3053-3062.
Perkins BA, Caskey CT, Brar P, Dec E, Karow DS, Kahn AM, Hou YC, Shah N, Boeldt D, Coughlin E, Hands G, Lavrenko V, Yu J, Procko A, Appis J, Dale AM, Guo L, Jönsson TJ, Wittmann BM, Bartha I, Ramakrishnan S, Bernal A, Brewer JB, Brewerton S, Biggs WH, Turpaz Y, Venter JC. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 Apr 3; 115: 3686-3691.
Shah N, Hou YC, Yu HC, Sainger R, Caskey CT, Venter JC, Telenti A. Identification of Misclassified ClinVar Variants via Disease Population Prevalence. Am J Hum Genet. 2018 Apr 5; 102: 609-619.
Tang H, Kirkness EF, Lippert C, Biggs WH, Fabani M, Guzman E, Ramakrishnan S, Lavrenko V, Kakaradov B, Hou C, Hicks B, Heckerman D, Och FJ, Caskey CT, Venter JC, Telenti A. Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes. Am J Hum Genet. 2017 Nov 2; 101: 700-715.
View More Publications
- Hou YC, Neidich JA, Duncavage EJ, Spencer DH, Schroeder MC. Clinical whole-genome sequencing in cancer diagnosis. Hum Mutat. 2022 Nov; 43: 1519-1530.
- Hou YC, Evenson MJ, Corliss MM, Mahapatra L, Aldawood A, Carpentieri DF, Chamlin SL, Kulungowski AM, Madan-Khetarpal S, Sebastian J, Pet MA, Coughlin CC, Willing MC, Pearson GD, Setty BA, El-Haffaf Z, Cottrell CE, Parikh BA, Krysiak K, Schroeder MC, Heusel JW, Neidich JA, Cao Y. A Comparative Analysis of RAS Variants in Patients with Disorders of Somatic Mosaicism. Genet Med. 2022 Nov 29;
- Starosta RT, Hou YC, Leestma K, Singh P, Viehl L, Manwaring L, Granadillo JL, Schroeder MC, Colombo JN, Whitehead H, Dickson PI, Hulbert ML, Nguyen HT. Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations. Front Pediatr. 2022; 10: 944178.
- Sams EI, Ng JK, Tate V, Claire Hou YC, Cao Y, Antonacci-Fulton L, Belhassan K, Neidich J, Mitra RD, Cole FS, Dickson P, Milbrandt J, Turner TN. From karyotypes to precision genomics in 9p deletion and duplication syndromes. HGG Adv. 2022 Jan 13; 3: 100081.
- Hou YC, Yu HC, Martin R, Cirulli ET, Schenker-Ahmed NM, Hicks M, Cohen IV, Jönsson TJ, Heister R, Napier L, Swisher CL, Dominguez S, Tang H, Li W, Perkins BA, Barea J, Rybak C, Smith E, Duchicela K, Doney M, Brar P, Hernandez N, Kirkness EF, Kahn AM, Venter JC, Karow DS, Caskey CT. Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging. Proc Natl Acad Sci U S A. 2020 Feb 11; 117: 3053-3062.
- Perkins BA, Caskey CT, Brar P, Dec E, Karow DS, Kahn AM, Hou YC, Shah N, Boeldt D, Coughlin E, Hands G, Lavrenko V, Yu J, Procko A, Appis J, Dale AM, Guo L, Jönsson TJ, Wittmann BM, Bartha I, Ramakrishnan S, Bernal A, Brewer JB, Brewerton S, Biggs WH, Turpaz Y, Venter JC. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 Apr 3; 115: 3686-3691.
- Shah N, Hou YC, Yu HC, Sainger R, Caskey CT, Venter JC, Telenti A. Identification of Misclassified ClinVar Variants via Disease Population Prevalence. Am J Hum Genet. 2018 Apr 5; 102: 609-619.
- Tang H, Kirkness EF, Lippert C, Biggs WH, Fabani M, Guzman E, Ramakrishnan S, Lavrenko V, Kakaradov B, Hou C, Hicks B, Heckerman D, Och FJ, Caskey CT, Venter JC, Telenti A. Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes. Am J Hum Genet. 2017 Nov 2; 101: 700-715.
Education
Fellowship
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Date Completed: 06/30/2022
Graduate School
The University of British Columbia
Date Completed: 07/01/2009
Education
Fellowship
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Date Completed: 06/30/2022
Graduate School
The University of British Columbia
Date Completed: 07/01/2009
Education
Fellowship
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Date Completed: 06/30/2022
Graduate School
The University of British Columbia
Date Completed: 07/01/2009
Fellowship
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Date Completed: 06/30/2022
Graduate School
The University of British Columbia
Date Completed: 07/01/2009
Fellowship
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Date Completed: 06/30/2022
Graduate School
The University of British Columbia
Date Completed: 07/01/2009
Professional Experience
2015 - 2020 Human Longevity Inc., Principal Scientist, Clinical Genetics2014 - 2015 Pathway Genomics, Genetics Scientist R&D
Professional Experience
2015 - 2020 Human Longevity Inc., Principal Scientist, Clinical Genetics2014 - 2015 Pathway Genomics, Genetics Scientist R&D
Professional Experience
2015 - 2020 Human Longevity Inc., Principal Scientist, Clinical Genetics2014 - 2015 Pathway Genomics, Genetics Scientist R&D
2015 - 2020 Human Longevity Inc., Principal Scientist, Clinical Genetics2014 - 2015 Pathway Genomics, Genetics Scientist R&D
2015 - 2020 Human Longevity Inc., Principal Scientist, Clinical Genetics
Contact Information
Institute for Genomic Medicine
Call us at: (614) 355-5907
Email Ying ChenClaire Hou
575 Children’s CrossroadColumbus, OH 43215 (map)
Contact Information
Institute for Genomic Medicine
Call us at: (614) 355-5907
Email Ying ChenClaire Hou
575 Children’s CrossroadColumbus, OH 43215 (map)
Contact Information
Institute for Genomic Medicine
Call us at: (614) 355-5907
Email Ying ChenClaire Hou
575 Children’s CrossroadColumbus, OH 43215 (map)
Institute for Genomic Medicine
Call us at: (614) 355-5907
Email Ying ChenClaire Hou
575 Children’s CrossroadColumbus, OH 43215 (map)
Call us at: (614) 355-5907
Email Ying ChenClaire Hou
575 Children’s CrossroadColumbus, OH 43215 (map)
Call us at: (614) 355-5907
Email Ying ChenClaire Hou
575 Children’s CrossroadColumbus, OH 43215 (map)
- Call us at:
- (614) 355-5907
- Email Ying ChenClaire Hou
- 575 Children’s CrossroadColumbus, OH 43215 (map)
