New Study Conducted By Nationwide Childrens Hospital Finds Compounds Show Promise In Blocking Stat3 Signaling As Treatment For Osteosarcoma
A study appearing in the journal Investigational New Drugs and conducted by researchers at Nationwide Children’s Hospital, discovered that two new small molecule inhibitors are showing promise in blocking STAT3, a protein linked to the most common malignant bone tumor, osteosarcoma. These small molecule inhibitors – one derived from a portion of the turmeric spice – may serve as a new, non-toxic treatment for these deadly tumors. Osteosarcoma is aggressive and its treatment outlook has not changed significantly over the last 20 years....