Prenatal Magnesium Sulfate May Not Reduce Cerebral Palsy Severity As Once Believed
(COLUMBUS, Ohio) - A large randomized controlled trial showed in 2008 that when pregnant women at imminent risk of preterm delivery were given magnesium sulfate, their children had reduced rates of moderate or severe cerebral palsy. As a result of the trial, funded by Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health (NIH), many delivery hospitals implemented magnesium administration policies. But a new study from Nationwide Children’s Hospital and The Ohio State University Wexner Medical Center calls into question whether these labor-intensive magnesium administrations – which are given intravenously in a hospital over a 12 hour span before birth – have an effect outside of the controlled environment of a trial....