Contact Information
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Fax us at: (614) 722-3443
PediatricsCritical Care700 Children’s DrColumbus, OH 43205 (map)
Learn more about Mark W. Hall
Biography
Mark W. Hall, MD, FCCM, is a professor in the Department of Pediatrics, Division of Critical Care Medicine at Nationwide Children’s Hospital and The Ohio State University College of Medicine. He is the Chief of the Division of Critical Care Medicine at Nationwide Children’s Hospital, Development Board Endowed Chair in Critical Care Medicine and Director of the Immune Surveillance Laboratory at The Research Institute at Nationwide Children’s Hospital in the Center for Clinical and Translational Research. His primary area of research focuses on the immunobiology of pediatric critical illness, with active projects investigating measures of immune function, mechanisms and risk factors for critical illness-induced immune suppression, and clinical trials of immunostimulatory therapies to restore immune function in the ICU. Dr. Hall’s immunology work spans the spectrum of basic, translational, and clinical science and includes clinical conditions such as trauma, burns, sepsis, and cardiopulmonary bypass. Dr. Hall is the Principal Investigator for Nationwide Children’s Hospital in the NICHD’s Collaborative Pediatric Critical Care Research Network (CPCCRN) and is an active member of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) research network.
“In the Division of Critical Care Medicine at Nationwide Children's Hospital, we strive to provide the highest quality, safest care in the country to critically ill children and their families while generating new, cutting-edge knowledge, and training the next generation of clinician-scientists.”
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Academic and Clinical Areas
Critical Care
Division Chief
Pediatric Critical Care Fellowship
Faculty
Center for Clinical and Translational Research
Principal Investigator
Neonatology
Principal Investigator
Center for Pediatric Trauma Research
Affiliate Faculty
Primary Department
Pediatrics
Primary Section
Critical Care
Awards, Honors & Organizations
Golden Stethoscope Award, Nationwide Children’s Hospital, 2019 Outstanding Faculty Educator, Department of Pediatrics, Nationwide Children’s Hospital, 2018 Distinguished CHEST Educator, American College of Chest Physicians, 2017 Distinguished Alumnus Award, University of Pittsburgh Department of Critical Care Medicine, 2016 Development Board Endowed Chair in Critical Care, Nationwide Children’s Hospital, 2015 Immunology Specialty Award, Society of Critical Care Medicine, 2013 Presidential Citation, Society of Critical Care Medicine, 2013 Excellence in Teaching Award, The Ohio State University College of Medicine, 2013 Poster Competition Winner, Clinical Fellow Category, Nationwide Children’s Hospital (Awarded to Ryan Nofziger MD: Fellow, Mark W. Hall: Mentor), 2012 Pediatric Critical Care Award (Hall: Senior Author), World Congress of Pediatric Intensive and Critical Care, 2012 Presidential Citation, Society of Critical Care Medicine, 2012 Scientific Award, Society of Critical Care Medicine, 2012 Outstanding Clinical/Translational Fellow Publication Award, Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Presidential Citation, Society of Critical Care Medicine, 2011 Poster Competition Winner, The Research Institute at Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Annual Scientific Award, SCCM, 2010 Clinical Research Award, Pediatric Critical Care Colloquium (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2010 Renal Specialty Award, SCCM, 2008 Fellow’s Patient Oriented Research Award (Awarded to David J. Marquardt, MD: Fellow; Mark W. Hall: Mentor), Nationwide Children’s Hospital, 2007 Research Citation Award, SCCM, 2006 Grant Morrow III Award for Outstanding Teaching and Clinical Practice, Nationwide Children’s Hospital House Staff, 2004 Educational Scholarship Award, SCCM, 2004 Educational Scholarship Award, SCCM, 2002 Educational Scholarship Award, SCCM, 2001 SCCM Pediatric Research Award, 2000 Jeffrey Farkas Memorial Intern Teaching Award, Children’s Hospital of Pittsburgh, 1995 Listed, Best Doctors in America Fellow, American College of Critical Care Medicine, 2012 - Present Member, Society of Pediatric Research, 2009 - Present Member, American Thoracic Society, 2006 - Present Fellow, American Academy of Pediatrics, 2003 - Present Member, Society of Critical Care Medicine (SCCM), 1999 - Present Chief Resident, Children’s Hospital of Pittsburgh, 1998 - Present Member, Alpha Omega Alpha Medical Honor Society, University of Virginia School of Medicine, 1993 - Present
Research
Lab(s)
Center for Clinical and Translational Research
The Immune Surveillance Laboratory at The Research institute at Nationwide Children’s Hospital is a high-throughput clinical and translational research laboratory dedicated to understanding the immune response to critical illness. The laboratory provides immune function testing services for single- and multi-center studies of immune function in critically ill children across North America. Publications
Berg RA, Morgan RW, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM. Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study. Crit Care Med. 2023 Jan 1; 51: 91-102.
Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Michael Dean J, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, KirkpatrickN T, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, NaimCE MY, Notterman D, Page K, Pollack MM, Qunibi D, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Calcium Use during Paediatric In-hospital Cardiac Arrest is Associated with Worse Outcomes. Resuscitation. 2022 Dec 21; 109673.
Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC Jr, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators. Association of Asthma with Treatments and Outcomes in Children with Critical Influenza. J Allergy Clin Immunol Pract. 2022 Nov 12;
LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS Jr, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2022 Nov 7;
Ross CE, Burns JP, Grossestreuer AV, Bhattarai P, McKiernan CA, Franks JD, Lehmann S, Sorcher JL, Sharron MP, Wai K, Al-Wahab H, Boukas K, Hall MW, Ru G, Sen AI, Rajasekhar HR, Kleinman LC, McGuire JK, Arrington AS, Munoz-Rivas F, Osborne CM, Shekerdemian LS. Trends in Disease Severity Among Critically Ill Children With Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Multicenter Cohort Study in the United States. Pediatr Crit Care Med. 2022 Nov 17;
Horvat CM, Fabio A, Nagin DS, Banks RK, Qin Y, Park HJ, Kernan KF, Canna SW, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Sward K, Holubkov R, Notterman DA, Dean JM, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels. Pediatr Crit Care Med. 2022 Sep 30;
Zambrano LD, Ly KN, Link-Gelles R, Newhams MM, Akande M, Wu MJ, Feldstein LR, Tarquinio KM, Sahni LC, Riggs BJ, Singh AR, Fitzgerald JC, Schuster JE, Giuliano JS Jr, Englund JA, Hume JR, Hall MW, Osborne CM, Doymaz S, Rowan CM, Babbitt CJ, Clouser KN, Horwitz SM, Chou J, Patel MM, Hobbs C, Randolph AG, Campbell AP, Overcoming COVID-19 Investigators.. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. Pediatr Infect Dis J. 2022 Sep 7;
Bline KE, Muszynski JA, Guess AJ, Menocha S, Moore-Clingenpeel MD, Popelka JK, Hensley JM, Steele LM, Goldthwaite IC, Jedreski KJ, Hall MW. Novel Identification of Myeloid-Derived Suppressor Cells in Children With Septic Shock. Pediatr Crit Care Med. 2022 Sep 8;
Morgan RW, Wolfe HA, Reeder RW, Alvey JS, Frazier AH, Friess SH, Maa T, McQuillen PS, Meert KL, Nadkarni VM, Sharron MP, Siems A, Yates AR, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Hall M, Hehir D, Horvat CM, Huard LL, Manga A, Mourani PM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa AF, Berg RA, Sutton RM. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022 Sep 2;
Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFlu) Investigators and the TOPMed Investigators.. DDX58 is Associated with Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 Aug 20;
Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host respiratory transcriptome signature associated with poor outcome in children with influenza-Staphylococcus aureus pneumonia. J Infect Dis. 2022 Jul 28;
Cashen K, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators.. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 Jul 26;
Morin L, Hall M, de Souza D, Guoping L, Jabornisky R, Shime N, Ranjit S, Gilholm P, Nakagawa S, Zimmerman JJ, Sorce LR, Argent A, Kissoon N, Tissières P, Watson RS, Schlapbach LJ, Pediatric Sepsis Definition Taskforce.. The Current and Future State of Pediatric Sepsis Definitions: An International Survey. Pediatrics. 2022 Jun 1; 149:
Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Soma VL, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG, Pediatric Intensive Care Influenza., Overcoming COVID-19 Investigators.. Life-Threatening Complications of Influenza versus COVID-19 in U.S. Children. Clin Infect Dis. 2022 Jun 19;
Salud D, Reeder RW, Banks RK, Meert KL, Berg RA, Zuppa A, Newth CJ, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Varni JW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med. 2022 Jun 10;
Qin Y, Kernan KF, Fan Z, Park HJ, Kim S, Canna SW, Kellum JA, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Michael Dean J, Carcillo JA. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 May 7; 26: 128.
Ames SG, Banks RK, Zinter MS, Fink EL, McQuillen PS, Hall MW, Zuppa A, Meert KL, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Berg RA, Mareboina M, Holubkov R, Dean JM, Notterman DA, Sapru A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2022 Apr 22;
Thakkar RK, Penatzer J, Simon S, Steele L, Fabia R, Groner JI, Keesari R, Hall M. Measures of Adaptive Immune Function Predict the Risk of Nosocomial Infection in Pediatric Burn Patients. J Burn Care Res. 2022 Apr 18;
Tsitsiklis A, Osborne CM, Kamm J, Williamson K, Kalantar K, Dudas G, Caldera S, Lyden A, Tan M, Neff N, Soesanto V, Harris JK, Ambroggio L, Maddux AB, Carpenter TC, Reeder RW, Locandro C, Simões EAF, Leroue MK, Hall MW, Zuppa AF, Carcillo J, Meert KL, Sapru A, Pollack MM, McQuillen PS, Notterman DA, Dean JM, Zinter MS, Wagner BD, DeRisi JL, Mourani PM, Langelier CR. Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics. Lancet Microbe. 2022 Apr; 3: e284-e293.
ICU-RESUS and Eunice Kennedy Shriver National Institute of Child Health., Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups., Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bishop R, Bochkoris M, Burns C, Diddle JW, Federman M, Fernandez R, Franzon D, Frazier AH, Friess SH, Graham K, Hehir D, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Schneiter C, Sharron MP, Siems A, Srivastava N, Tabbutt S, Tilford B, Viteri S, Berg RA, Bell MJ, Carcillo JA, Carpenter TC, Dean JM, Fink EL, Hall M, McQuillen PS, Meert KL, Mourani PM, Notterman D, Pollack MM, Sapru A, Wessel D, Yates AR, Zuppa AF. Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial. JAMA. 2022 Mar 8; 327: 934-945.
Yates AR, Berger JT, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Notterman DA, Holubkov R, Dean JM, Wessel DL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients. Pediatr Crit Care Med. 2022 Feb 23;
Farhat MH, Shadley JD, Halligan NLN, Hall MW, Popova AP, Quasney MW, Dahmer MK. Differences in the Genomic Profiles of Immunoparalyzed and Nonimmunoparalyzed Children With Sepsis: A Pilot Study. Pediatr Crit Care Med. 2022 Feb 1; 23: 79-88.
Sribnick EA, Popovich PG, Hall MW. Central nervous system injury-induced immune suppression. Neurosurg Focus. 2022 Feb; 52: E10.
Olson SM, Newhams MM, Halasa NB, Feldstein LR, Novak T, Weiss SL, Coates BM, Schuster JE, Schwarz AJ, Maddux AB, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Stewart LS, Barnes JR, Patel MM, Randolph AG, Pediatric Intensive Care Influenza Investigators .. Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. Clin Infect Dis. 2022 Jan 13;
Schuster JE, Halasa NB, Nakamura M, Levy ER, Fitzgerald JC, Young CC, Newhams MM, Bourgeois F, Staat MA, Hobbs CV, Dapul H, Feldstein LR, Jackson AM, Mack EH, Walker TC, Maddux AB, Spinella PC, Loftis LL, Kong M, Rowan CM, Bembea MM, McLaughlin GE, Hall MW, Babbitt CJ, Maamari M, Zinter MS, Cvijanovich NZ, Michelson KN, Gertz SJ, Carroll CL, Thomas NJ, Giuliano JS, Singh AR, Hymes SR, Schwarz AJ, McGuire JK, Nofziger RA, Flori HR, Clouser KN, Wellnitz K, Cullimore ML, Hume JR, Patel M, Randolph AG, Overcoming COVID-19 Investigators.. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 Jan 12;
Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo JA. Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis. J Clin Immunol. 2022 Jan 1;
Hall MW, Carcillo JA, Cornell T, Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative.. Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022 Jan 1; 149: S91-S98.
Bembea MM, Agus M, Akcan-Arikan A, Alexander P, Basu R, Bennett TD, Bohn D, Brandão LR, Brown AM, Carcillo JA, Checchia P, Cholette J, Cheifetz IM, Cornell T, Doctor A, Eckerle M, Erickson S, Farris RWD, Faustino EVS, Fitzgerald JC, Fuhrman DY, Giuliano JS, Guilliams K, Gaies M, Gorga SM, Hall M, Hanson SJ, Hartman M, Hassinger AB, Irving SY, Jeffries H, Jouvet P, Kannan S, Karam O, Khemani RG, Kissoon N, Lacroix J, Laussen P, Leclerc F, Lee JH, Leteurtre S, Lobner K, McKiernan PJ, Menon K, Monagle P, Muszynski JA, Odetola F, Parker R, Pathan N, Pierce RW, Pineda J, Prince JM, Robinson KA, Rowan CM, Ryerson LM, Sanchez-Pinto LN, Schlapbach LJ, Selewski DT, Shekerdemian LS, Simon D, Smith LS, Squires JE, Squires RH, Sutherland SM, Ouellette Y, Spaeder MC, Srinivasan V, Steiner ME, Tasker RC, Thiagarajan R, Thomas N, Tissieres P, Traube C, Tucci M, Typpo KV, Wainwright MS, Ward SL, Watson RS, Weiss S, Whitney J, Willson D, Wynn JL, Yeyha N, Zimmerman JJ. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics. 2022 Jan 1; 149: S1-S12.
Muszynski JA, Banks R, Reeder RW, Hall MW, Berg RA, Zuppa A, Shanley TP, Cornell TT, Newth CJL, Pollack MM, Wessel D, Doctor A, Lin JC, Harrison RE, Meert KL, Dean JM, Holubkov R, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Outcomes Associated With Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study. Shock. 2022 Jan 1; 57: 88-94.
Mertz C, Glowinski R, Cohen SH, Mertz S, Ye F, Hall MW, Peeples ME, King T, Wang H, Leber AL, Sanchez PJ, Ramilo O, Mejias A. Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019. J Infect Dis. 2022 Jan 18; 225: 208-213.
Mukherjee R, Tompkins CA, Ostberg NP, Joshi AU, Massis LM, Vijayan V, Gera K, Monack D, Cornell TT, Hall MW, Mochly-Rosen D, Haileselassie B. Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance. Crit Care Med. 2022 Jan 24;
Penatzer JA, Alexander R, Simon S, Wolfe A, Breuer J, Hensley J, Fabia R, Hall M, Thakkar RK. Early detection of soluble CD27, BTLA, and TIM-3 predicts the development of nosocomial infection in pediatric burn patients. Front Immunol. 2022; 13: 940835.
Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2021 Dec 21;
Sribnick EA, Warner T, Hall MW. Traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma leads to immunosuppression and splenic alterations. J Neuroimmunol. 2021 Dec 15; 361: 577723.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Notterman DA, Colville G, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Post-Traumatic Growth in Parents following Their Child's Death in a Pediatric Intensive Care Unit. J Palliat Med. 2021 Oct 5;
Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, Overcoming COVID-19 Investigators.. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40: 101112.
Bline KE, Hall MW. Immune Function in Critically Ill Septic Children. Pathogens. 2021 Sep 25; 10:
Diaz-Diaz A, Bunsow E, Garcia-Maurino C, Moore-Clingenpeel M, Naples J, Juergensen A, Mertz S, Wang H, Leber AL, Gern J, Hall MW, Cohen DM, Ramilo O, Mejias A. Nasopharyngeal Codetection of H. influenzae and S. pneumoniae and Respiratory Syncytial Virus Disease Outcomes in Children. J Infect Dis. 2021 Sep 20;
Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators., Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates AR. Factors Associated With Functional Impairment After Pediatric Injury. JAMA Surg. 2021 Aug 1; 156: e212058.
Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS Jr, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 Jul 1; 385: 23-34.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Complicated Grief, Depression and Post-Traumatic Stress Symptoms Among Bereaved Parents following their Child's Death in the Pediatric Intensive Care Unit: A Follow-Up Study. Am J Hosp Palliat Care. 2021 May 5; 10499091211015913.
Snyder A, Jedreski K, Fitch J, Wijeratne S, Wetzel A, Hensley J, Flowers M, Bline K, Hall MW, Muszynski JA. Transcriptomic Profiles in Children With Septic Shock With or Without Immunoparalysis. Front Immunol. 2021; 12: 733834.
Pinto NP, Berg RA, Zuppa AF, Newth CJ, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Nadkarni VM, Reeder RW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Front Pediatr. 2021; 9: 675374.
Srouji LS, Moore-Clingenpeel M, Hensley J, Steele L, Greathouse K, Anglim L, Hanson-Huber L, Nateri J, Nicol K, Hall MW, Ramilo O, Muszynski JA. Shock Severity Modifies Associations Between RBC Transfusion in the First 48 Hours of Sepsis Onset and the Duration of Organ Dysfunction in Critically Ill Septic Children. Pediatr Crit Care Med. 2020 Aug; 21: e475-e484.
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 Aug; 48: 1120-1128.
Hall MW, Joshi I, Leal L, Ooi EE. Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention. Clin Infect Dis. 2020 Jul 1;
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 May 11;
Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, Heidemann SM, Kleinman LC, Sen AI, Hall MW, Priestley MA, McGuire JK, Boukas K, Sharron MP, Burns JP, International COVID-19 PICU Collaborative.. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. 2020 May 11;
Sribnick EA, Hensley J, Moore-Clingenpeel M, Muszynski JA, Thakkar RK, Hall MW. Nosocomial Infection Following Severe Traumatic Injury in Children. Pediatr Crit Care Med. 2020 May; 21: 443-450.
Gertz SJ, McArthur J, Hsing DD, Nitu ME, Smith LS, Loomis A, Fitzgerald JC, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Cheifetz IM, Rowan CM, Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network.. Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant. Transpl Infect Dis. 2020 Apr 19; e13297.
Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Apr 21;
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 329-337.
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 319-328.
Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators.. RIG-I and TLR4 Responses and Adverse Outcomes in Pediatric Influenza-Related Critical Illness. J Allergy Clin Immunol. 2020 Feb 5;
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: e52-e106.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: 186-195.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 Feb; 46: 10-67.
Sribnick EA, Weber MD, Hall MW. Innate immune suppression after traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma. J Neuroimmunol. 2019 Dec 15; 337: 577073.
Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure. Pediatr Crit Care Med. 2019 Sep 18;
La Count S, Lovett ME, Zhao S, Kline D, O'Brien NF, Hall MW, Sribnick EA. Factors Associated With Poor Outcome in Pediatric Near-Hanging Injuries. J Emerg Med. 2019 Jul; 57: 21-28.
Hungerford JL, O'Brien N, Moore-Clingenpeel M, Sribnick EA, Sargel C, Hall M, Leonard JR, Tobias JD. Remifentanil for Sedation of Children With Traumatic Brain Injury. J Intensive Care Med. 2019 Jul; 34: 557-562.
Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Zuppa AF, Graham K, Twelves C, Diliberto MA, Landis WP, Tomanio E, Kwok J, Bell MJ, Abraham A, Sapru A, Alkhouli MF, Heidemann S, Pawluszka A, Hall MW, Steele L, Shanley TP, Weber M, Dalton HJ, Bell A, Mourani PM, Malone K, Locandro C, Coleman W, Peterson A, Thelen J, Doctor A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators.. The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation. 2019 Jun 6; 141: 88-95.
Thakkar RK, Weiss SL, Fitzgerald JC, Keele L, Thomas NJ, Nadkarni VM, Muszynski JA, Hall MW, SPROUT Investigators., Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis. J Surg Res. 2019 May 7; 242: 100-110.
Hall MW. Immune Modulation in Pediatric Sepsis. J Pediatr Intensive Care. 2019 Mar; 8: 42-50.
Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, Han Y, Easley KA, Knezevic A, Dai T, Paden M, Carcillo JA, Thrombocytopenia-Associated Multiple Organ Failure (TAMOF) Network Study Group.. Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience. Crit Care Med. 2019 Mar; 47: e173-e181.
Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, PALISI PICFLU Investigators., Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10: 1005.
Karsies T, Moore-Clingenpeel M, Hall M. Development and Validation of a Model to Predict Growth of Potentially Antibiotic-Resistant Gram-Negative Bacilli in Critically Ill Children With Suspected Infection. Open Forum Infect Dis. 2018 Nov; 5: ofy278.
Rowan CM, McArthur J, Hsing DD, Gertz SJ, Smith LS, Loomis A, Fitzgerald JC, Nitu ME, Moser EAS, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. Acute Respiratory Failure in Pediatric Hematopoietic Cell Transplantation: A Multicenter Study. Crit Care Med. 2018 Oct; 46: e967-e974.
Stenson EK, Cvijanovich NZ, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Jain PN, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Wong HR, Anas N. Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock. Intensive Care Med. 2018 Oct 15;
Willson DF, Hall M, Beardsley A, Hoot M, Kirby A, Hays S, Erickson S, Truemper E, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Pediatric Ventilator-Associated Events: Analysis of the Pediatric Ventilator-Associated Infection Data. Pediatr Crit Care Med. 2018 Sep 18;
Muszynski JA, Nofziger R, Moore-Clingenpeel M, Greathouse K, Anglim L, Steele L, Hensley J, Hanson-Huber L, Nateri J, Ramilo O, Hall MW. Early Immune Function and Duration of Organ Dysfunction in Critically III Children with Sepsis. Am J Respir Crit Care Med. 2018 Aug 1; 198: 361-369.
Thakkar RK, Diltz Z, Drews JD, Wheeler KK, Shi J, Devine R, Fabia R, Hall M. Abnormal lymphocyte response after pediatric thermal injury is associated with adverse outcomes. J Surg Res. 2018 Aug; 228: 221-227.
Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt K, Pediatric Intensive Care Influenza (PICFLU) Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network.. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children with Influenza-Related Critical Illness. Clin Infect Dis. 2018 Jun 9;
Rowan CM, Loomis A, McArthur J, Smith LS, Gertz SJ, Fitzgerald JC, Nitu ME, Moser EA, Hsing DD, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient. Respir Care. 2018 Apr; 63: 404-411.
Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR. Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. Pediatr Crit Care Med. 2018 Feb; 19: 155-160.
Devine RA, Diltz Z, Hall MW, Thakkar RK. The systemic immune response to pediatric thermal injury. Int J Burns Trauma. 2018; 8: 6-16.
Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK. The Functional Immune Response of Patients on Extracorporeal Life Support. ASAIO J. 2018 Jan 10;
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Education
Date of Appointment at Nationwide Children’s Hospital: 09/27/2002
Board Certifications
Pediatric Critical Care Pediatrics
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2002
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2001
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/23/1998
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1997
Internship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1995
Medical School
University of Virginia
Date Completed: 05/22/1994
Professional Experience
2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2012 - 2020 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Associate Professor of Pediatrics2002 - 2012 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Assistant Professor of Pediatrics2001 - 2002 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Research Fellow/Instructor1998 - 2001 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Fellow1997 - 1998 Pediatrics,Children’s Hospital of Pittsburgh, Chief Resident/Instructor1994 - 1997 Pediatrics, Children’s Hospital of Pittsburgh, Resident
Contact Information
Pediatrics
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
Critical Care700 Children's DrColumbus, OH 43205 (map)
Contact Information
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
PediatricsCritical Care700 Children’s DrColumbus, OH 43205 (map)
Learn more about Mark W. Hall
Biography
Mark W. Hall, MD, FCCM, is a professor in the Department of Pediatrics, Division of Critical Care Medicine at Nationwide Children’s Hospital and The Ohio State University College of Medicine. He is the Chief of the Division of Critical Care Medicine at Nationwide Children’s Hospital, Development Board Endowed Chair in Critical Care Medicine and Director of the Immune Surveillance Laboratory at The Research Institute at Nationwide Children’s Hospital in the Center for Clinical and Translational Research. His primary area of research focuses on the immunobiology of pediatric critical illness, with active projects investigating measures of immune function, mechanisms and risk factors for critical illness-induced immune suppression, and clinical trials of immunostimulatory therapies to restore immune function in the ICU. Dr. Hall’s immunology work spans the spectrum of basic, translational, and clinical science and includes clinical conditions such as trauma, burns, sepsis, and cardiopulmonary bypass. Dr. Hall is the Principal Investigator for Nationwide Children’s Hospital in the NICHD’s Collaborative Pediatric Critical Care Research Network (CPCCRN) and is an active member of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) research network.
“In the Division of Critical Care Medicine at Nationwide Children's Hospital, we strive to provide the highest quality, safest care in the country to critically ill children and their families while generating new, cutting-edge knowledge, and training the next generation of clinician-scientists.”
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Academic and Clinical Areas
Critical Care
Division Chief
Pediatric Critical Care Fellowship
Faculty
Center for Clinical and Translational Research
Principal Investigator
Neonatology
Principal Investigator
Center for Pediatric Trauma Research
Affiliate Faculty
Primary Department
Pediatrics
Primary Section
Critical Care
Awards, Honors & Organizations
Golden Stethoscope Award, Nationwide Children’s Hospital, 2019 Outstanding Faculty Educator, Department of Pediatrics, Nationwide Children’s Hospital, 2018 Distinguished CHEST Educator, American College of Chest Physicians, 2017 Distinguished Alumnus Award, University of Pittsburgh Department of Critical Care Medicine, 2016 Development Board Endowed Chair in Critical Care, Nationwide Children’s Hospital, 2015 Immunology Specialty Award, Society of Critical Care Medicine, 2013 Presidential Citation, Society of Critical Care Medicine, 2013 Excellence in Teaching Award, The Ohio State University College of Medicine, 2013 Poster Competition Winner, Clinical Fellow Category, Nationwide Children’s Hospital (Awarded to Ryan Nofziger MD: Fellow, Mark W. Hall: Mentor), 2012 Pediatric Critical Care Award (Hall: Senior Author), World Congress of Pediatric Intensive and Critical Care, 2012 Presidential Citation, Society of Critical Care Medicine, 2012 Scientific Award, Society of Critical Care Medicine, 2012 Outstanding Clinical/Translational Fellow Publication Award, Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Presidential Citation, Society of Critical Care Medicine, 2011 Poster Competition Winner, The Research Institute at Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Annual Scientific Award, SCCM, 2010 Clinical Research Award, Pediatric Critical Care Colloquium (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2010 Renal Specialty Award, SCCM, 2008 Fellow’s Patient Oriented Research Award (Awarded to David J. Marquardt, MD: Fellow; Mark W. Hall: Mentor), Nationwide Children’s Hospital, 2007 Research Citation Award, SCCM, 2006 Grant Morrow III Award for Outstanding Teaching and Clinical Practice, Nationwide Children’s Hospital House Staff, 2004 Educational Scholarship Award, SCCM, 2004 Educational Scholarship Award, SCCM, 2002 Educational Scholarship Award, SCCM, 2001 SCCM Pediatric Research Award, 2000 Jeffrey Farkas Memorial Intern Teaching Award, Children’s Hospital of Pittsburgh, 1995 Listed, Best Doctors in America Fellow, American College of Critical Care Medicine, 2012 - Present Member, Society of Pediatric Research, 2009 - Present Member, American Thoracic Society, 2006 - Present Fellow, American Academy of Pediatrics, 2003 - Present Member, Society of Critical Care Medicine (SCCM), 1999 - Present Chief Resident, Children’s Hospital of Pittsburgh, 1998 - Present Member, Alpha Omega Alpha Medical Honor Society, University of Virginia School of Medicine, 1993 - Present
Research
Lab(s)
Center for Clinical and Translational Research
The Immune Surveillance Laboratory at The Research institute at Nationwide Children’s Hospital is a high-throughput clinical and translational research laboratory dedicated to understanding the immune response to critical illness. The laboratory provides immune function testing services for single- and multi-center studies of immune function in critically ill children across North America. Publications
Berg RA, Morgan RW, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM. Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study. Crit Care Med. 2023 Jan 1; 51: 91-102.
Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Michael Dean J, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, KirkpatrickN T, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, NaimCE MY, Notterman D, Page K, Pollack MM, Qunibi D, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Calcium Use during Paediatric In-hospital Cardiac Arrest is Associated with Worse Outcomes. Resuscitation. 2022 Dec 21; 109673.
Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC Jr, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators. Association of Asthma with Treatments and Outcomes in Children with Critical Influenza. J Allergy Clin Immunol Pract. 2022 Nov 12;
LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS Jr, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2022 Nov 7;
Ross CE, Burns JP, Grossestreuer AV, Bhattarai P, McKiernan CA, Franks JD, Lehmann S, Sorcher JL, Sharron MP, Wai K, Al-Wahab H, Boukas K, Hall MW, Ru G, Sen AI, Rajasekhar HR, Kleinman LC, McGuire JK, Arrington AS, Munoz-Rivas F, Osborne CM, Shekerdemian LS. Trends in Disease Severity Among Critically Ill Children With Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Multicenter Cohort Study in the United States. Pediatr Crit Care Med. 2022 Nov 17;
Horvat CM, Fabio A, Nagin DS, Banks RK, Qin Y, Park HJ, Kernan KF, Canna SW, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Sward K, Holubkov R, Notterman DA, Dean JM, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels. Pediatr Crit Care Med. 2022 Sep 30;
Zambrano LD, Ly KN, Link-Gelles R, Newhams MM, Akande M, Wu MJ, Feldstein LR, Tarquinio KM, Sahni LC, Riggs BJ, Singh AR, Fitzgerald JC, Schuster JE, Giuliano JS Jr, Englund JA, Hume JR, Hall MW, Osborne CM, Doymaz S, Rowan CM, Babbitt CJ, Clouser KN, Horwitz SM, Chou J, Patel MM, Hobbs C, Randolph AG, Campbell AP, Overcoming COVID-19 Investigators.. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. Pediatr Infect Dis J. 2022 Sep 7;
Bline KE, Muszynski JA, Guess AJ, Menocha S, Moore-Clingenpeel MD, Popelka JK, Hensley JM, Steele LM, Goldthwaite IC, Jedreski KJ, Hall MW. Novel Identification of Myeloid-Derived Suppressor Cells in Children With Septic Shock. Pediatr Crit Care Med. 2022 Sep 8;
Morgan RW, Wolfe HA, Reeder RW, Alvey JS, Frazier AH, Friess SH, Maa T, McQuillen PS, Meert KL, Nadkarni VM, Sharron MP, Siems A, Yates AR, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Hall M, Hehir D, Horvat CM, Huard LL, Manga A, Mourani PM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa AF, Berg RA, Sutton RM. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022 Sep 2;
Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFlu) Investigators and the TOPMed Investigators.. DDX58 is Associated with Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 Aug 20;
Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host respiratory transcriptome signature associated with poor outcome in children with influenza-Staphylococcus aureus pneumonia. J Infect Dis. 2022 Jul 28;
Cashen K, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators.. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 Jul 26;
Morin L, Hall M, de Souza D, Guoping L, Jabornisky R, Shime N, Ranjit S, Gilholm P, Nakagawa S, Zimmerman JJ, Sorce LR, Argent A, Kissoon N, Tissières P, Watson RS, Schlapbach LJ, Pediatric Sepsis Definition Taskforce.. The Current and Future State of Pediatric Sepsis Definitions: An International Survey. Pediatrics. 2022 Jun 1; 149:
Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Soma VL, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG, Pediatric Intensive Care Influenza., Overcoming COVID-19 Investigators.. Life-Threatening Complications of Influenza versus COVID-19 in U.S. Children. Clin Infect Dis. 2022 Jun 19;
Salud D, Reeder RW, Banks RK, Meert KL, Berg RA, Zuppa A, Newth CJ, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Varni JW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med. 2022 Jun 10;
Qin Y, Kernan KF, Fan Z, Park HJ, Kim S, Canna SW, Kellum JA, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Michael Dean J, Carcillo JA. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 May 7; 26: 128.
Ames SG, Banks RK, Zinter MS, Fink EL, McQuillen PS, Hall MW, Zuppa A, Meert KL, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Berg RA, Mareboina M, Holubkov R, Dean JM, Notterman DA, Sapru A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2022 Apr 22;
Thakkar RK, Penatzer J, Simon S, Steele L, Fabia R, Groner JI, Keesari R, Hall M. Measures of Adaptive Immune Function Predict the Risk of Nosocomial Infection in Pediatric Burn Patients. J Burn Care Res. 2022 Apr 18;
Tsitsiklis A, Osborne CM, Kamm J, Williamson K, Kalantar K, Dudas G, Caldera S, Lyden A, Tan M, Neff N, Soesanto V, Harris JK, Ambroggio L, Maddux AB, Carpenter TC, Reeder RW, Locandro C, Simões EAF, Leroue MK, Hall MW, Zuppa AF, Carcillo J, Meert KL, Sapru A, Pollack MM, McQuillen PS, Notterman DA, Dean JM, Zinter MS, Wagner BD, DeRisi JL, Mourani PM, Langelier CR. Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics. Lancet Microbe. 2022 Apr; 3: e284-e293.
ICU-RESUS and Eunice Kennedy Shriver National Institute of Child Health., Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups., Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bishop R, Bochkoris M, Burns C, Diddle JW, Federman M, Fernandez R, Franzon D, Frazier AH, Friess SH, Graham K, Hehir D, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Schneiter C, Sharron MP, Siems A, Srivastava N, Tabbutt S, Tilford B, Viteri S, Berg RA, Bell MJ, Carcillo JA, Carpenter TC, Dean JM, Fink EL, Hall M, McQuillen PS, Meert KL, Mourani PM, Notterman D, Pollack MM, Sapru A, Wessel D, Yates AR, Zuppa AF. Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial. JAMA. 2022 Mar 8; 327: 934-945.
Yates AR, Berger JT, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Notterman DA, Holubkov R, Dean JM, Wessel DL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients. Pediatr Crit Care Med. 2022 Feb 23;
Farhat MH, Shadley JD, Halligan NLN, Hall MW, Popova AP, Quasney MW, Dahmer MK. Differences in the Genomic Profiles of Immunoparalyzed and Nonimmunoparalyzed Children With Sepsis: A Pilot Study. Pediatr Crit Care Med. 2022 Feb 1; 23: 79-88.
Sribnick EA, Popovich PG, Hall MW. Central nervous system injury-induced immune suppression. Neurosurg Focus. 2022 Feb; 52: E10.
Olson SM, Newhams MM, Halasa NB, Feldstein LR, Novak T, Weiss SL, Coates BM, Schuster JE, Schwarz AJ, Maddux AB, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Stewart LS, Barnes JR, Patel MM, Randolph AG, Pediatric Intensive Care Influenza Investigators .. Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. Clin Infect Dis. 2022 Jan 13;
Schuster JE, Halasa NB, Nakamura M, Levy ER, Fitzgerald JC, Young CC, Newhams MM, Bourgeois F, Staat MA, Hobbs CV, Dapul H, Feldstein LR, Jackson AM, Mack EH, Walker TC, Maddux AB, Spinella PC, Loftis LL, Kong M, Rowan CM, Bembea MM, McLaughlin GE, Hall MW, Babbitt CJ, Maamari M, Zinter MS, Cvijanovich NZ, Michelson KN, Gertz SJ, Carroll CL, Thomas NJ, Giuliano JS, Singh AR, Hymes SR, Schwarz AJ, McGuire JK, Nofziger RA, Flori HR, Clouser KN, Wellnitz K, Cullimore ML, Hume JR, Patel M, Randolph AG, Overcoming COVID-19 Investigators.. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 Jan 12;
Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo JA. Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis. J Clin Immunol. 2022 Jan 1;
Hall MW, Carcillo JA, Cornell T, Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative.. Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022 Jan 1; 149: S91-S98.
Bembea MM, Agus M, Akcan-Arikan A, Alexander P, Basu R, Bennett TD, Bohn D, Brandão LR, Brown AM, Carcillo JA, Checchia P, Cholette J, Cheifetz IM, Cornell T, Doctor A, Eckerle M, Erickson S, Farris RWD, Faustino EVS, Fitzgerald JC, Fuhrman DY, Giuliano JS, Guilliams K, Gaies M, Gorga SM, Hall M, Hanson SJ, Hartman M, Hassinger AB, Irving SY, Jeffries H, Jouvet P, Kannan S, Karam O, Khemani RG, Kissoon N, Lacroix J, Laussen P, Leclerc F, Lee JH, Leteurtre S, Lobner K, McKiernan PJ, Menon K, Monagle P, Muszynski JA, Odetola F, Parker R, Pathan N, Pierce RW, Pineda J, Prince JM, Robinson KA, Rowan CM, Ryerson LM, Sanchez-Pinto LN, Schlapbach LJ, Selewski DT, Shekerdemian LS, Simon D, Smith LS, Squires JE, Squires RH, Sutherland SM, Ouellette Y, Spaeder MC, Srinivasan V, Steiner ME, Tasker RC, Thiagarajan R, Thomas N, Tissieres P, Traube C, Tucci M, Typpo KV, Wainwright MS, Ward SL, Watson RS, Weiss S, Whitney J, Willson D, Wynn JL, Yeyha N, Zimmerman JJ. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics. 2022 Jan 1; 149: S1-S12.
Muszynski JA, Banks R, Reeder RW, Hall MW, Berg RA, Zuppa A, Shanley TP, Cornell TT, Newth CJL, Pollack MM, Wessel D, Doctor A, Lin JC, Harrison RE, Meert KL, Dean JM, Holubkov R, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Outcomes Associated With Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study. Shock. 2022 Jan 1; 57: 88-94.
Mertz C, Glowinski R, Cohen SH, Mertz S, Ye F, Hall MW, Peeples ME, King T, Wang H, Leber AL, Sanchez PJ, Ramilo O, Mejias A. Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019. J Infect Dis. 2022 Jan 18; 225: 208-213.
Mukherjee R, Tompkins CA, Ostberg NP, Joshi AU, Massis LM, Vijayan V, Gera K, Monack D, Cornell TT, Hall MW, Mochly-Rosen D, Haileselassie B. Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance. Crit Care Med. 2022 Jan 24;
Penatzer JA, Alexander R, Simon S, Wolfe A, Breuer J, Hensley J, Fabia R, Hall M, Thakkar RK. Early detection of soluble CD27, BTLA, and TIM-3 predicts the development of nosocomial infection in pediatric burn patients. Front Immunol. 2022; 13: 940835.
Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2021 Dec 21;
Sribnick EA, Warner T, Hall MW. Traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma leads to immunosuppression and splenic alterations. J Neuroimmunol. 2021 Dec 15; 361: 577723.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Notterman DA, Colville G, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Post-Traumatic Growth in Parents following Their Child's Death in a Pediatric Intensive Care Unit. J Palliat Med. 2021 Oct 5;
Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, Overcoming COVID-19 Investigators.. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40: 101112.
Bline KE, Hall MW. Immune Function in Critically Ill Septic Children. Pathogens. 2021 Sep 25; 10:
Diaz-Diaz A, Bunsow E, Garcia-Maurino C, Moore-Clingenpeel M, Naples J, Juergensen A, Mertz S, Wang H, Leber AL, Gern J, Hall MW, Cohen DM, Ramilo O, Mejias A. Nasopharyngeal Codetection of H. influenzae and S. pneumoniae and Respiratory Syncytial Virus Disease Outcomes in Children. J Infect Dis. 2021 Sep 20;
Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators., Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates AR. Factors Associated With Functional Impairment After Pediatric Injury. JAMA Surg. 2021 Aug 1; 156: e212058.
Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS Jr, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 Jul 1; 385: 23-34.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Complicated Grief, Depression and Post-Traumatic Stress Symptoms Among Bereaved Parents following their Child's Death in the Pediatric Intensive Care Unit: A Follow-Up Study. Am J Hosp Palliat Care. 2021 May 5; 10499091211015913.
Snyder A, Jedreski K, Fitch J, Wijeratne S, Wetzel A, Hensley J, Flowers M, Bline K, Hall MW, Muszynski JA. Transcriptomic Profiles in Children With Septic Shock With or Without Immunoparalysis. Front Immunol. 2021; 12: 733834.
Pinto NP, Berg RA, Zuppa AF, Newth CJ, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Nadkarni VM, Reeder RW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Front Pediatr. 2021; 9: 675374.
Srouji LS, Moore-Clingenpeel M, Hensley J, Steele L, Greathouse K, Anglim L, Hanson-Huber L, Nateri J, Nicol K, Hall MW, Ramilo O, Muszynski JA. Shock Severity Modifies Associations Between RBC Transfusion in the First 48 Hours of Sepsis Onset and the Duration of Organ Dysfunction in Critically Ill Septic Children. Pediatr Crit Care Med. 2020 Aug; 21: e475-e484.
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 Aug; 48: 1120-1128.
Hall MW, Joshi I, Leal L, Ooi EE. Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention. Clin Infect Dis. 2020 Jul 1;
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 May 11;
Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, Heidemann SM, Kleinman LC, Sen AI, Hall MW, Priestley MA, McGuire JK, Boukas K, Sharron MP, Burns JP, International COVID-19 PICU Collaborative.. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. 2020 May 11;
Sribnick EA, Hensley J, Moore-Clingenpeel M, Muszynski JA, Thakkar RK, Hall MW. Nosocomial Infection Following Severe Traumatic Injury in Children. Pediatr Crit Care Med. 2020 May; 21: 443-450.
Gertz SJ, McArthur J, Hsing DD, Nitu ME, Smith LS, Loomis A, Fitzgerald JC, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Cheifetz IM, Rowan CM, Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network.. Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant. Transpl Infect Dis. 2020 Apr 19; e13297.
Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Apr 21;
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 329-337.
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 319-328.
Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators.. RIG-I and TLR4 Responses and Adverse Outcomes in Pediatric Influenza-Related Critical Illness. J Allergy Clin Immunol. 2020 Feb 5;
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: e52-e106.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: 186-195.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 Feb; 46: 10-67.
Sribnick EA, Weber MD, Hall MW. Innate immune suppression after traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma. J Neuroimmunol. 2019 Dec 15; 337: 577073.
Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure. Pediatr Crit Care Med. 2019 Sep 18;
La Count S, Lovett ME, Zhao S, Kline D, O'Brien NF, Hall MW, Sribnick EA. Factors Associated With Poor Outcome in Pediatric Near-Hanging Injuries. J Emerg Med. 2019 Jul; 57: 21-28.
Hungerford JL, O'Brien N, Moore-Clingenpeel M, Sribnick EA, Sargel C, Hall M, Leonard JR, Tobias JD. Remifentanil for Sedation of Children With Traumatic Brain Injury. J Intensive Care Med. 2019 Jul; 34: 557-562.
Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Zuppa AF, Graham K, Twelves C, Diliberto MA, Landis WP, Tomanio E, Kwok J, Bell MJ, Abraham A, Sapru A, Alkhouli MF, Heidemann S, Pawluszka A, Hall MW, Steele L, Shanley TP, Weber M, Dalton HJ, Bell A, Mourani PM, Malone K, Locandro C, Coleman W, Peterson A, Thelen J, Doctor A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators.. The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation. 2019 Jun 6; 141: 88-95.
Thakkar RK, Weiss SL, Fitzgerald JC, Keele L, Thomas NJ, Nadkarni VM, Muszynski JA, Hall MW, SPROUT Investigators., Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis. J Surg Res. 2019 May 7; 242: 100-110.
Hall MW. Immune Modulation in Pediatric Sepsis. J Pediatr Intensive Care. 2019 Mar; 8: 42-50.
Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, Han Y, Easley KA, Knezevic A, Dai T, Paden M, Carcillo JA, Thrombocytopenia-Associated Multiple Organ Failure (TAMOF) Network Study Group.. Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience. Crit Care Med. 2019 Mar; 47: e173-e181.
Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, PALISI PICFLU Investigators., Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10: 1005.
Karsies T, Moore-Clingenpeel M, Hall M. Development and Validation of a Model to Predict Growth of Potentially Antibiotic-Resistant Gram-Negative Bacilli in Critically Ill Children With Suspected Infection. Open Forum Infect Dis. 2018 Nov; 5: ofy278.
Rowan CM, McArthur J, Hsing DD, Gertz SJ, Smith LS, Loomis A, Fitzgerald JC, Nitu ME, Moser EAS, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. Acute Respiratory Failure in Pediatric Hematopoietic Cell Transplantation: A Multicenter Study. Crit Care Med. 2018 Oct; 46: e967-e974.
Stenson EK, Cvijanovich NZ, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Jain PN, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Wong HR, Anas N. Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock. Intensive Care Med. 2018 Oct 15;
Willson DF, Hall M, Beardsley A, Hoot M, Kirby A, Hays S, Erickson S, Truemper E, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Pediatric Ventilator-Associated Events: Analysis of the Pediatric Ventilator-Associated Infection Data. Pediatr Crit Care Med. 2018 Sep 18;
Muszynski JA, Nofziger R, Moore-Clingenpeel M, Greathouse K, Anglim L, Steele L, Hensley J, Hanson-Huber L, Nateri J, Ramilo O, Hall MW. Early Immune Function and Duration of Organ Dysfunction in Critically III Children with Sepsis. Am J Respir Crit Care Med. 2018 Aug 1; 198: 361-369.
Thakkar RK, Diltz Z, Drews JD, Wheeler KK, Shi J, Devine R, Fabia R, Hall M. Abnormal lymphocyte response after pediatric thermal injury is associated with adverse outcomes. J Surg Res. 2018 Aug; 228: 221-227.
Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt K, Pediatric Intensive Care Influenza (PICFLU) Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network.. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children with Influenza-Related Critical Illness. Clin Infect Dis. 2018 Jun 9;
Rowan CM, Loomis A, McArthur J, Smith LS, Gertz SJ, Fitzgerald JC, Nitu ME, Moser EA, Hsing DD, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient. Respir Care. 2018 Apr; 63: 404-411.
Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR. Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. Pediatr Crit Care Med. 2018 Feb; 19: 155-160.
Devine RA, Diltz Z, Hall MW, Thakkar RK. The systemic immune response to pediatric thermal injury. Int J Burns Trauma. 2018; 8: 6-16.
Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK. The Functional Immune Response of Patients on Extracorporeal Life Support. ASAIO J. 2018 Jan 10;
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Education
Date of Appointment at Nationwide Children’s Hospital: 09/27/2002
Board Certifications
Pediatric Critical Care Pediatrics
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2002
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2001
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/23/1998
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1997
Internship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1995
Medical School
University of Virginia
Date Completed: 05/22/1994
Professional Experience
2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2012 - 2020 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Associate Professor of Pediatrics2002 - 2012 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Assistant Professor of Pediatrics2001 - 2002 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Research Fellow/Instructor1998 - 2001 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Fellow1997 - 1998 Pediatrics,Children’s Hospital of Pittsburgh, Chief Resident/Instructor1994 - 1997 Pediatrics, Children’s Hospital of Pittsburgh, Resident
Contact Information
Pediatrics
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
Critical Care700 Children's DrColumbus, OH 43205 (map)
Contact Information
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
PediatricsCritical Care700 Children’s DrColumbus, OH 43205 (map)
Learn more about Mark W. Hall
Contact Information
- Call us at:
- (614) 722-3435
- Fax us at:
- (614) 722-3443
- PediatricsCritical Care700 Children’s DrColumbus, OH 43205 (map)
Learn more about Mark W. Hall
Biography
Mark W. Hall, MD, FCCM, is a professor in the Department of Pediatrics, Division of Critical Care Medicine at Nationwide Children’s Hospital and The Ohio State University College of Medicine. He is the Chief of the Division of Critical Care Medicine at Nationwide Children’s Hospital, Development Board Endowed Chair in Critical Care Medicine and Director of the Immune Surveillance Laboratory at The Research Institute at Nationwide Children’s Hospital in the Center for Clinical and Translational Research. His primary area of research focuses on the immunobiology of pediatric critical illness, with active projects investigating measures of immune function, mechanisms and risk factors for critical illness-induced immune suppression, and clinical trials of immunostimulatory therapies to restore immune function in the ICU. Dr. Hall’s immunology work spans the spectrum of basic, translational, and clinical science and includes clinical conditions such as trauma, burns, sepsis, and cardiopulmonary bypass. Dr. Hall is the Principal Investigator for Nationwide Children’s Hospital in the NICHD’s Collaborative Pediatric Critical Care Research Network (CPCCRN) and is an active member of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) research network.
Biography
Mark W. Hall, MD, FCCM, is a professor in the Department of Pediatrics, Division of Critical Care Medicine at Nationwide Children’s Hospital and The Ohio State University College of Medicine. He is the Chief of the Division of Critical Care Medicine at Nationwide Children’s Hospital, Development Board Endowed Chair in Critical Care Medicine and Director of the Immune Surveillance Laboratory at The Research Institute at Nationwide Children’s Hospital in the Center for Clinical and Translational Research. His primary area of research focuses on the immunobiology of pediatric critical illness, with active projects investigating measures of immune function, mechanisms and risk factors for critical illness-induced immune suppression, and clinical trials of immunostimulatory therapies to restore immune function in the ICU. Dr. Hall’s immunology work spans the spectrum of basic, translational, and clinical science and includes clinical conditions such as trauma, burns, sepsis, and cardiopulmonary bypass. Dr. Hall is the Principal Investigator for Nationwide Children’s Hospital in the NICHD’s Collaborative Pediatric Critical Care Research Network (CPCCRN) and is an active member of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) research network.
Biography
Mark W. Hall, MD, FCCM, is a professor in the Department of Pediatrics, Division of Critical Care Medicine at Nationwide Children’s Hospital and The Ohio State University College of Medicine. He is the Chief of the Division of Critical Care Medicine at Nationwide Children’s Hospital, Development Board Endowed Chair in Critical Care Medicine and Director of the Immune Surveillance Laboratory at The Research Institute at Nationwide Children’s Hospital in the Center for Clinical and Translational Research. His primary area of research focuses on the immunobiology of pediatric critical illness, with active projects investigating measures of immune function, mechanisms and risk factors for critical illness-induced immune suppression, and clinical trials of immunostimulatory therapies to restore immune function in the ICU. Dr. Hall’s immunology work spans the spectrum of basic, translational, and clinical science and includes clinical conditions such as trauma, burns, sepsis, and cardiopulmonary bypass. Dr. Hall is the Principal Investigator for Nationwide Children’s Hospital in the NICHD’s Collaborative Pediatric Critical Care Research Network (CPCCRN) and is an active member of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) research network.
Mark W. Hall, MD, FCCM, is a professor in the Department of Pediatrics, Division of Critical Care Medicine at Nationwide Children’s Hospital and The Ohio State University College of Medicine. He is the Chief of the Division of Critical Care Medicine at Nationwide Children’s Hospital, Development Board Endowed Chair in Critical Care Medicine and Director of the Immune Surveillance Laboratory at The Research Institute at Nationwide Children’s Hospital in the Center for Clinical and Translational Research. His primary area of research focuses on the immunobiology of pediatric critical illness, with active projects investigating measures of immune function, mechanisms and risk factors for critical illness-induced immune suppression, and clinical trials of immunostimulatory therapies to restore immune function in the ICU. Dr. Hall’s immunology work spans the spectrum of basic, translational, and clinical science and includes clinical conditions such as trauma, burns, sepsis, and cardiopulmonary bypass. Dr. Hall is the Principal Investigator for Nationwide Children’s Hospital in the NICHD’s Collaborative Pediatric Critical Care Research Network (CPCCRN) and is an active member of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) research network.
Mark W. Hall, MD, FCCM, is a professor in the Department of Pediatrics, Division of Critical Care Medicine at Nationwide Children’s Hospital and The Ohio State University College of Medicine. He is the Chief of the Division of Critical Care Medicine at Nationwide Children’s Hospital, Development Board Endowed Chair in Critical Care Medicine and Director of the Immune Surveillance Laboratory at The Research Institute at Nationwide Children’s Hospital in the Center for Clinical and Translational Research.
His primary area of research focuses on the immunobiology of pediatric critical illness, with active projects investigating measures of immune function, mechanisms and risk factors for critical illness-induced immune suppression, and clinical trials of immunostimulatory therapies to restore immune function in the ICU. Dr. Hall’s immunology work spans the spectrum of basic, translational, and clinical science and includes clinical conditions such as trauma, burns, sepsis, and cardiopulmonary bypass. Dr. Hall is the Principal Investigator for Nationwide Children’s Hospital in the NICHD’s Collaborative Pediatric Critical Care Research Network (CPCCRN) and is an active member of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) research network.
“In the Division of Critical Care Medicine at Nationwide Children's Hospital, we strive to provide the highest quality, safest care in the country to critically ill children and their families while generating new, cutting-edge knowledge, and training the next generation of clinician-scientists.”
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Locations
Main Campus of Nationwide Children’s Hospital
Locations
Main Campus of Nationwide Children’s Hospital
Locations
Main Campus of Nationwide Children’s Hospital
- Main Campus of Nationwide Children’s Hospital
Academic and Clinical Areas
Critical Care
Division Chief
Pediatric Critical Care Fellowship
Faculty
Center for Clinical and Translational Research
Principal Investigator
Neonatology
Principal Investigator
Center for Pediatric Trauma Research
Affiliate Faculty
Primary Department
Pediatrics
Primary Section
Critical Care
Academic and Clinical Areas
Critical Care
Division Chief
Pediatric Critical Care Fellowship
Faculty
Center for Clinical and Translational Research
Principal Investigator
Neonatology
Principal Investigator
Center for Pediatric Trauma Research
Affiliate Faculty
Primary Department
Pediatrics
Primary Section
Critical Care
Academic and Clinical Areas
Critical Care
Division Chief
Pediatric Critical Care Fellowship
Faculty
Center for Clinical and Translational Research
Principal Investigator
Neonatology
Principal Investigator
Center for Pediatric Trauma Research
Affiliate Faculty
Primary Department
Pediatrics
Primary Section
Critical Care
Critical Care
Division Chief
Pediatric Critical Care Fellowship
Faculty
Center for Clinical and Translational Research
Principal Investigator
Neonatology
Principal Investigator
Center for Pediatric Trauma Research
Affiliate Faculty
Primary Department
Pediatrics
Primary Section
Critical Care
- Critical Care
- Division Chief
- Pediatric Critical Care Fellowship
- Faculty
- Center for Clinical and Translational Research
- Principal Investigator
- Neonatology
- Principal Investigator
- Center for Pediatric Trauma Research
- Affiliate Faculty
- Primary Department
- Pediatrics
- Primary Section
- Critical Care
Awards, Honors & Organizations
Golden Stethoscope Award, Nationwide Children’s Hospital, 2019 Outstanding Faculty Educator, Department of Pediatrics, Nationwide Children’s Hospital, 2018 Distinguished CHEST Educator, American College of Chest Physicians, 2017 Distinguished Alumnus Award, University of Pittsburgh Department of Critical Care Medicine, 2016 Development Board Endowed Chair in Critical Care, Nationwide Children’s Hospital, 2015 Immunology Specialty Award, Society of Critical Care Medicine, 2013 Presidential Citation, Society of Critical Care Medicine, 2013 Excellence in Teaching Award, The Ohio State University College of Medicine, 2013 Poster Competition Winner, Clinical Fellow Category, Nationwide Children’s Hospital (Awarded to Ryan Nofziger MD: Fellow, Mark W. Hall: Mentor), 2012 Pediatric Critical Care Award (Hall: Senior Author), World Congress of Pediatric Intensive and Critical Care, 2012 Presidential Citation, Society of Critical Care Medicine, 2012 Scientific Award, Society of Critical Care Medicine, 2012 Outstanding Clinical/Translational Fellow Publication Award, Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Presidential Citation, Society of Critical Care Medicine, 2011 Poster Competition Winner, The Research Institute at Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Annual Scientific Award, SCCM, 2010 Clinical Research Award, Pediatric Critical Care Colloquium (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2010 Renal Specialty Award, SCCM, 2008 Fellow’s Patient Oriented Research Award (Awarded to David J. Marquardt, MD: Fellow; Mark W. Hall: Mentor), Nationwide Children’s Hospital, 2007 Research Citation Award, SCCM, 2006 Grant Morrow III Award for Outstanding Teaching and Clinical Practice, Nationwide Children’s Hospital House Staff, 2004 Educational Scholarship Award, SCCM, 2004 Educational Scholarship Award, SCCM, 2002 Educational Scholarship Award, SCCM, 2001 SCCM Pediatric Research Award, 2000 Jeffrey Farkas Memorial Intern Teaching Award, Children’s Hospital of Pittsburgh, 1995 Listed, Best Doctors in America Fellow, American College of Critical Care Medicine, 2012 - Present Member, Society of Pediatric Research, 2009 - Present Member, American Thoracic Society, 2006 - Present Fellow, American Academy of Pediatrics, 2003 - Present Member, Society of Critical Care Medicine (SCCM), 1999 - Present Chief Resident, Children’s Hospital of Pittsburgh, 1998 - Present Member, Alpha Omega Alpha Medical Honor Society, University of Virginia School of Medicine, 1993 - Present
Awards, Honors & Organizations
Golden Stethoscope Award, Nationwide Children’s Hospital, 2019 Outstanding Faculty Educator, Department of Pediatrics, Nationwide Children’s Hospital, 2018 Distinguished CHEST Educator, American College of Chest Physicians, 2017 Distinguished Alumnus Award, University of Pittsburgh Department of Critical Care Medicine, 2016 Development Board Endowed Chair in Critical Care, Nationwide Children’s Hospital, 2015 Immunology Specialty Award, Society of Critical Care Medicine, 2013 Presidential Citation, Society of Critical Care Medicine, 2013 Excellence in Teaching Award, The Ohio State University College of Medicine, 2013 Poster Competition Winner, Clinical Fellow Category, Nationwide Children’s Hospital (Awarded to Ryan Nofziger MD: Fellow, Mark W. Hall: Mentor), 2012 Pediatric Critical Care Award (Hall: Senior Author), World Congress of Pediatric Intensive and Critical Care, 2012 Presidential Citation, Society of Critical Care Medicine, 2012 Scientific Award, Society of Critical Care Medicine, 2012 Outstanding Clinical/Translational Fellow Publication Award, Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Presidential Citation, Society of Critical Care Medicine, 2011 Poster Competition Winner, The Research Institute at Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Annual Scientific Award, SCCM, 2010 Clinical Research Award, Pediatric Critical Care Colloquium (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2010 Renal Specialty Award, SCCM, 2008 Fellow’s Patient Oriented Research Award (Awarded to David J. Marquardt, MD: Fellow; Mark W. Hall: Mentor), Nationwide Children’s Hospital, 2007 Research Citation Award, SCCM, 2006 Grant Morrow III Award for Outstanding Teaching and Clinical Practice, Nationwide Children’s Hospital House Staff, 2004 Educational Scholarship Award, SCCM, 2004 Educational Scholarship Award, SCCM, 2002 Educational Scholarship Award, SCCM, 2001 SCCM Pediatric Research Award, 2000 Jeffrey Farkas Memorial Intern Teaching Award, Children’s Hospital of Pittsburgh, 1995 Listed, Best Doctors in America Fellow, American College of Critical Care Medicine, 2012 - Present Member, Society of Pediatric Research, 2009 - Present Member, American Thoracic Society, 2006 - Present Fellow, American Academy of Pediatrics, 2003 - Present Member, Society of Critical Care Medicine (SCCM), 1999 - Present Chief Resident, Children’s Hospital of Pittsburgh, 1998 - Present Member, Alpha Omega Alpha Medical Honor Society, University of Virginia School of Medicine, 1993 - Present
Awards, Honors & Organizations
Golden Stethoscope Award, Nationwide Children’s Hospital, 2019 Outstanding Faculty Educator, Department of Pediatrics, Nationwide Children’s Hospital, 2018 Distinguished CHEST Educator, American College of Chest Physicians, 2017 Distinguished Alumnus Award, University of Pittsburgh Department of Critical Care Medicine, 2016 Development Board Endowed Chair in Critical Care, Nationwide Children’s Hospital, 2015 Immunology Specialty Award, Society of Critical Care Medicine, 2013 Presidential Citation, Society of Critical Care Medicine, 2013 Excellence in Teaching Award, The Ohio State University College of Medicine, 2013 Poster Competition Winner, Clinical Fellow Category, Nationwide Children’s Hospital (Awarded to Ryan Nofziger MD: Fellow, Mark W. Hall: Mentor), 2012 Pediatric Critical Care Award (Hall: Senior Author), World Congress of Pediatric Intensive and Critical Care, 2012 Presidential Citation, Society of Critical Care Medicine, 2012 Scientific Award, Society of Critical Care Medicine, 2012 Outstanding Clinical/Translational Fellow Publication Award, Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Presidential Citation, Society of Critical Care Medicine, 2011 Poster Competition Winner, The Research Institute at Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Annual Scientific Award, SCCM, 2010 Clinical Research Award, Pediatric Critical Care Colloquium (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2010 Renal Specialty Award, SCCM, 2008 Fellow’s Patient Oriented Research Award (Awarded to David J. Marquardt, MD: Fellow; Mark W. Hall: Mentor), Nationwide Children’s Hospital, 2007 Research Citation Award, SCCM, 2006 Grant Morrow III Award for Outstanding Teaching and Clinical Practice, Nationwide Children’s Hospital House Staff, 2004 Educational Scholarship Award, SCCM, 2004 Educational Scholarship Award, SCCM, 2002 Educational Scholarship Award, SCCM, 2001 SCCM Pediatric Research Award, 2000 Jeffrey Farkas Memorial Intern Teaching Award, Children’s Hospital of Pittsburgh, 1995 Listed, Best Doctors in America Fellow, American College of Critical Care Medicine, 2012 - Present Member, Society of Pediatric Research, 2009 - Present Member, American Thoracic Society, 2006 - Present Fellow, American Academy of Pediatrics, 2003 - Present Member, Society of Critical Care Medicine (SCCM), 1999 - Present Chief Resident, Children’s Hospital of Pittsburgh, 1998 - Present Member, Alpha Omega Alpha Medical Honor Society, University of Virginia School of Medicine, 1993 - Present
Golden Stethoscope Award, Nationwide Children’s Hospital, 2019 Outstanding Faculty Educator, Department of Pediatrics, Nationwide Children’s Hospital, 2018 Distinguished CHEST Educator, American College of Chest Physicians, 2017 Distinguished Alumnus Award, University of Pittsburgh Department of Critical Care Medicine, 2016 Development Board Endowed Chair in Critical Care, Nationwide Children’s Hospital, 2015 Immunology Specialty Award, Society of Critical Care Medicine, 2013 Presidential Citation, Society of Critical Care Medicine, 2013 Excellence in Teaching Award, The Ohio State University College of Medicine, 2013 Poster Competition Winner, Clinical Fellow Category, Nationwide Children’s Hospital (Awarded to Ryan Nofziger MD: Fellow, Mark W. Hall: Mentor), 2012 Pediatric Critical Care Award (Hall: Senior Author), World Congress of Pediatric Intensive and Critical Care, 2012 Presidential Citation, Society of Critical Care Medicine, 2012 Scientific Award, Society of Critical Care Medicine, 2012 Outstanding Clinical/Translational Fellow Publication Award, Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Presidential Citation, Society of Critical Care Medicine, 2011 Poster Competition Winner, The Research Institute at Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011 Annual Scientific Award, SCCM, 2010 Clinical Research Award, Pediatric Critical Care Colloquium (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2010 Renal Specialty Award, SCCM, 2008 Fellow’s Patient Oriented Research Award (Awarded to David J. Marquardt, MD: Fellow; Mark W. Hall: Mentor), Nationwide Children’s Hospital, 2007 Research Citation Award, SCCM, 2006 Grant Morrow III Award for Outstanding Teaching and Clinical Practice, Nationwide Children’s Hospital House Staff, 2004 Educational Scholarship Award, SCCM, 2004 Educational Scholarship Award, SCCM, 2002 Educational Scholarship Award, SCCM, 2001 SCCM Pediatric Research Award, 2000 Jeffrey Farkas Memorial Intern Teaching Award, Children’s Hospital of Pittsburgh, 1995 Listed, Best Doctors in America Fellow, American College of Critical Care Medicine, 2012 - Present Member, Society of Pediatric Research, 2009 - Present Member, American Thoracic Society, 2006 - Present Fellow, American Academy of Pediatrics, 2003 - Present Member, Society of Critical Care Medicine (SCCM), 1999 - Present Chief Resident, Children’s Hospital of Pittsburgh, 1998 - Present Member, Alpha Omega Alpha Medical Honor Society, University of Virginia School of Medicine, 1993 - Present
- Golden Stethoscope Award, Nationwide Children’s Hospital, 2019
- Outstanding Faculty Educator, Department of Pediatrics, Nationwide Children’s Hospital, 2018
- Distinguished CHEST Educator, American College of Chest Physicians, 2017
- Distinguished Alumnus Award, University of Pittsburgh Department of Critical Care Medicine, 2016
- Development Board Endowed Chair in Critical Care, Nationwide Children’s Hospital, 2015
- Immunology Specialty Award, Society of Critical Care Medicine, 2013
- Presidential Citation, Society of Critical Care Medicine, 2013
- Excellence in Teaching Award, The Ohio State University College of Medicine, 2013
- Poster Competition Winner, Clinical Fellow Category, Nationwide Children’s Hospital (Awarded to Ryan Nofziger MD: Fellow, Mark W. Hall: Mentor), 2012
- Pediatric Critical Care Award (Hall: Senior Author), World Congress of Pediatric Intensive and Critical Care, 2012
- Presidential Citation, Society of Critical Care Medicine, 2012
- Scientific Award, Society of Critical Care Medicine, 2012
- Outstanding Clinical/Translational Fellow Publication Award, Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011
- Presidential Citation, Society of Critical Care Medicine, 2011
- Poster Competition Winner, The Research Institute at Nationwide Children’s Hospital (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2011
- Annual Scientific Award, SCCM, 2010
- Clinical Research Award, Pediatric Critical Care Colloquium (Awarded to Jennifer A. Muszynski MD: Fellow; Mark W. Hall: Mentor), 2010
- Renal Specialty Award, SCCM, 2008
- Fellow’s Patient Oriented Research Award (Awarded to David J. Marquardt, MD: Fellow; Mark W. Hall: Mentor), Nationwide Children’s Hospital, 2007
- Research Citation Award, SCCM, 2006
- Grant Morrow III Award for Outstanding Teaching and Clinical Practice, Nationwide Children’s Hospital House Staff, 2004
- Educational Scholarship Award, SCCM, 2004
- Educational Scholarship Award, SCCM, 2002
- Educational Scholarship Award, SCCM, 2001
- SCCM Pediatric Research Award, 2000
- Jeffrey Farkas Memorial Intern Teaching Award, Children’s Hospital of Pittsburgh, 1995
- Listed, Best Doctors in America
- Fellow, American College of Critical Care Medicine, 2012 - Present
- Member, Society of Pediatric Research, 2009 - Present
- Member, American Thoracic Society, 2006 - Present
- Fellow, American Academy of Pediatrics, 2003 - Present
- Member, Society of Critical Care Medicine (SCCM), 1999 - Present
- Chief Resident, Children’s Hospital of Pittsburgh, 1998 - Present
- Member, Alpha Omega Alpha Medical Honor Society, University of Virginia School of Medicine, 1993 - Present
Research
Lab(s)
Center for Clinical and Translational Research
The Immune Surveillance Laboratory at The Research institute at Nationwide Children’s Hospital is a high-throughput clinical and translational research laboratory dedicated to understanding the immune response to critical illness. The laboratory provides immune function testing services for single- and multi-center studies of immune function in critically ill children across North America. Publications
Berg RA, Morgan RW, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM. Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study. Crit Care Med. 2023 Jan 1; 51: 91-102.
Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Michael Dean J, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, KirkpatrickN T, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, NaimCE MY, Notterman D, Page K, Pollack MM, Qunibi D, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Calcium Use during Paediatric In-hospital Cardiac Arrest is Associated with Worse Outcomes. Resuscitation. 2022 Dec 21; 109673.
Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC Jr, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators. Association of Asthma with Treatments and Outcomes in Children with Critical Influenza. J Allergy Clin Immunol Pract. 2022 Nov 12;
LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS Jr, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2022 Nov 7;
Ross CE, Burns JP, Grossestreuer AV, Bhattarai P, McKiernan CA, Franks JD, Lehmann S, Sorcher JL, Sharron MP, Wai K, Al-Wahab H, Boukas K, Hall MW, Ru G, Sen AI, Rajasekhar HR, Kleinman LC, McGuire JK, Arrington AS, Munoz-Rivas F, Osborne CM, Shekerdemian LS. Trends in Disease Severity Among Critically Ill Children With Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Multicenter Cohort Study in the United States. Pediatr Crit Care Med. 2022 Nov 17;
Horvat CM, Fabio A, Nagin DS, Banks RK, Qin Y, Park HJ, Kernan KF, Canna SW, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Sward K, Holubkov R, Notterman DA, Dean JM, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels. Pediatr Crit Care Med. 2022 Sep 30;
Zambrano LD, Ly KN, Link-Gelles R, Newhams MM, Akande M, Wu MJ, Feldstein LR, Tarquinio KM, Sahni LC, Riggs BJ, Singh AR, Fitzgerald JC, Schuster JE, Giuliano JS Jr, Englund JA, Hume JR, Hall MW, Osborne CM, Doymaz S, Rowan CM, Babbitt CJ, Clouser KN, Horwitz SM, Chou J, Patel MM, Hobbs C, Randolph AG, Campbell AP, Overcoming COVID-19 Investigators.. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. Pediatr Infect Dis J. 2022 Sep 7;
Bline KE, Muszynski JA, Guess AJ, Menocha S, Moore-Clingenpeel MD, Popelka JK, Hensley JM, Steele LM, Goldthwaite IC, Jedreski KJ, Hall MW. Novel Identification of Myeloid-Derived Suppressor Cells in Children With Septic Shock. Pediatr Crit Care Med. 2022 Sep 8;
Morgan RW, Wolfe HA, Reeder RW, Alvey JS, Frazier AH, Friess SH, Maa T, McQuillen PS, Meert KL, Nadkarni VM, Sharron MP, Siems A, Yates AR, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Hall M, Hehir D, Horvat CM, Huard LL, Manga A, Mourani PM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa AF, Berg RA, Sutton RM. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022 Sep 2;
Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFlu) Investigators and the TOPMed Investigators.. DDX58 is Associated with Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 Aug 20;
Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host respiratory transcriptome signature associated with poor outcome in children with influenza-Staphylococcus aureus pneumonia. J Infect Dis. 2022 Jul 28;
Cashen K, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators.. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 Jul 26;
Morin L, Hall M, de Souza D, Guoping L, Jabornisky R, Shime N, Ranjit S, Gilholm P, Nakagawa S, Zimmerman JJ, Sorce LR, Argent A, Kissoon N, Tissières P, Watson RS, Schlapbach LJ, Pediatric Sepsis Definition Taskforce.. The Current and Future State of Pediatric Sepsis Definitions: An International Survey. Pediatrics. 2022 Jun 1; 149:
Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Soma VL, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG, Pediatric Intensive Care Influenza., Overcoming COVID-19 Investigators.. Life-Threatening Complications of Influenza versus COVID-19 in U.S. Children. Clin Infect Dis. 2022 Jun 19;
Salud D, Reeder RW, Banks RK, Meert KL, Berg RA, Zuppa A, Newth CJ, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Varni JW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med. 2022 Jun 10;
Qin Y, Kernan KF, Fan Z, Park HJ, Kim S, Canna SW, Kellum JA, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Michael Dean J, Carcillo JA. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 May 7; 26: 128.
Ames SG, Banks RK, Zinter MS, Fink EL, McQuillen PS, Hall MW, Zuppa A, Meert KL, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Berg RA, Mareboina M, Holubkov R, Dean JM, Notterman DA, Sapru A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2022 Apr 22;
Thakkar RK, Penatzer J, Simon S, Steele L, Fabia R, Groner JI, Keesari R, Hall M. Measures of Adaptive Immune Function Predict the Risk of Nosocomial Infection in Pediatric Burn Patients. J Burn Care Res. 2022 Apr 18;
Tsitsiklis A, Osborne CM, Kamm J, Williamson K, Kalantar K, Dudas G, Caldera S, Lyden A, Tan M, Neff N, Soesanto V, Harris JK, Ambroggio L, Maddux AB, Carpenter TC, Reeder RW, Locandro C, Simões EAF, Leroue MK, Hall MW, Zuppa AF, Carcillo J, Meert KL, Sapru A, Pollack MM, McQuillen PS, Notterman DA, Dean JM, Zinter MS, Wagner BD, DeRisi JL, Mourani PM, Langelier CR. Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics. Lancet Microbe. 2022 Apr; 3: e284-e293.
ICU-RESUS and Eunice Kennedy Shriver National Institute of Child Health., Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups., Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bishop R, Bochkoris M, Burns C, Diddle JW, Federman M, Fernandez R, Franzon D, Frazier AH, Friess SH, Graham K, Hehir D, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Schneiter C, Sharron MP, Siems A, Srivastava N, Tabbutt S, Tilford B, Viteri S, Berg RA, Bell MJ, Carcillo JA, Carpenter TC, Dean JM, Fink EL, Hall M, McQuillen PS, Meert KL, Mourani PM, Notterman D, Pollack MM, Sapru A, Wessel D, Yates AR, Zuppa AF. Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial. JAMA. 2022 Mar 8; 327: 934-945.
Yates AR, Berger JT, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Notterman DA, Holubkov R, Dean JM, Wessel DL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients. Pediatr Crit Care Med. 2022 Feb 23;
Farhat MH, Shadley JD, Halligan NLN, Hall MW, Popova AP, Quasney MW, Dahmer MK. Differences in the Genomic Profiles of Immunoparalyzed and Nonimmunoparalyzed Children With Sepsis: A Pilot Study. Pediatr Crit Care Med. 2022 Feb 1; 23: 79-88.
Sribnick EA, Popovich PG, Hall MW. Central nervous system injury-induced immune suppression. Neurosurg Focus. 2022 Feb; 52: E10.
Olson SM, Newhams MM, Halasa NB, Feldstein LR, Novak T, Weiss SL, Coates BM, Schuster JE, Schwarz AJ, Maddux AB, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Stewart LS, Barnes JR, Patel MM, Randolph AG, Pediatric Intensive Care Influenza Investigators .. Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. Clin Infect Dis. 2022 Jan 13;
Schuster JE, Halasa NB, Nakamura M, Levy ER, Fitzgerald JC, Young CC, Newhams MM, Bourgeois F, Staat MA, Hobbs CV, Dapul H, Feldstein LR, Jackson AM, Mack EH, Walker TC, Maddux AB, Spinella PC, Loftis LL, Kong M, Rowan CM, Bembea MM, McLaughlin GE, Hall MW, Babbitt CJ, Maamari M, Zinter MS, Cvijanovich NZ, Michelson KN, Gertz SJ, Carroll CL, Thomas NJ, Giuliano JS, Singh AR, Hymes SR, Schwarz AJ, McGuire JK, Nofziger RA, Flori HR, Clouser KN, Wellnitz K, Cullimore ML, Hume JR, Patel M, Randolph AG, Overcoming COVID-19 Investigators.. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 Jan 12;
Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo JA. Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis. J Clin Immunol. 2022 Jan 1;
Hall MW, Carcillo JA, Cornell T, Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative.. Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022 Jan 1; 149: S91-S98.
Bembea MM, Agus M, Akcan-Arikan A, Alexander P, Basu R, Bennett TD, Bohn D, Brandão LR, Brown AM, Carcillo JA, Checchia P, Cholette J, Cheifetz IM, Cornell T, Doctor A, Eckerle M, Erickson S, Farris RWD, Faustino EVS, Fitzgerald JC, Fuhrman DY, Giuliano JS, Guilliams K, Gaies M, Gorga SM, Hall M, Hanson SJ, Hartman M, Hassinger AB, Irving SY, Jeffries H, Jouvet P, Kannan S, Karam O, Khemani RG, Kissoon N, Lacroix J, Laussen P, Leclerc F, Lee JH, Leteurtre S, Lobner K, McKiernan PJ, Menon K, Monagle P, Muszynski JA, Odetola F, Parker R, Pathan N, Pierce RW, Pineda J, Prince JM, Robinson KA, Rowan CM, Ryerson LM, Sanchez-Pinto LN, Schlapbach LJ, Selewski DT, Shekerdemian LS, Simon D, Smith LS, Squires JE, Squires RH, Sutherland SM, Ouellette Y, Spaeder MC, Srinivasan V, Steiner ME, Tasker RC, Thiagarajan R, Thomas N, Tissieres P, Traube C, Tucci M, Typpo KV, Wainwright MS, Ward SL, Watson RS, Weiss S, Whitney J, Willson D, Wynn JL, Yeyha N, Zimmerman JJ. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics. 2022 Jan 1; 149: S1-S12.
Muszynski JA, Banks R, Reeder RW, Hall MW, Berg RA, Zuppa A, Shanley TP, Cornell TT, Newth CJL, Pollack MM, Wessel D, Doctor A, Lin JC, Harrison RE, Meert KL, Dean JM, Holubkov R, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Outcomes Associated With Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study. Shock. 2022 Jan 1; 57: 88-94.
Mertz C, Glowinski R, Cohen SH, Mertz S, Ye F, Hall MW, Peeples ME, King T, Wang H, Leber AL, Sanchez PJ, Ramilo O, Mejias A. Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019. J Infect Dis. 2022 Jan 18; 225: 208-213.
Mukherjee R, Tompkins CA, Ostberg NP, Joshi AU, Massis LM, Vijayan V, Gera K, Monack D, Cornell TT, Hall MW, Mochly-Rosen D, Haileselassie B. Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance. Crit Care Med. 2022 Jan 24;
Penatzer JA, Alexander R, Simon S, Wolfe A, Breuer J, Hensley J, Fabia R, Hall M, Thakkar RK. Early detection of soluble CD27, BTLA, and TIM-3 predicts the development of nosocomial infection in pediatric burn patients. Front Immunol. 2022; 13: 940835.
Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2021 Dec 21;
Sribnick EA, Warner T, Hall MW. Traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma leads to immunosuppression and splenic alterations. J Neuroimmunol. 2021 Dec 15; 361: 577723.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Notterman DA, Colville G, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Post-Traumatic Growth in Parents following Their Child's Death in a Pediatric Intensive Care Unit. J Palliat Med. 2021 Oct 5;
Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, Overcoming COVID-19 Investigators.. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40: 101112.
Bline KE, Hall MW. Immune Function in Critically Ill Septic Children. Pathogens. 2021 Sep 25; 10:
Diaz-Diaz A, Bunsow E, Garcia-Maurino C, Moore-Clingenpeel M, Naples J, Juergensen A, Mertz S, Wang H, Leber AL, Gern J, Hall MW, Cohen DM, Ramilo O, Mejias A. Nasopharyngeal Codetection of H. influenzae and S. pneumoniae and Respiratory Syncytial Virus Disease Outcomes in Children. J Infect Dis. 2021 Sep 20;
Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators., Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates AR. Factors Associated With Functional Impairment After Pediatric Injury. JAMA Surg. 2021 Aug 1; 156: e212058.
Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS Jr, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 Jul 1; 385: 23-34.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Complicated Grief, Depression and Post-Traumatic Stress Symptoms Among Bereaved Parents following their Child's Death in the Pediatric Intensive Care Unit: A Follow-Up Study. Am J Hosp Palliat Care. 2021 May 5; 10499091211015913.
Snyder A, Jedreski K, Fitch J, Wijeratne S, Wetzel A, Hensley J, Flowers M, Bline K, Hall MW, Muszynski JA. Transcriptomic Profiles in Children With Septic Shock With or Without Immunoparalysis. Front Immunol. 2021; 12: 733834.
Pinto NP, Berg RA, Zuppa AF, Newth CJ, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Nadkarni VM, Reeder RW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Front Pediatr. 2021; 9: 675374.
Srouji LS, Moore-Clingenpeel M, Hensley J, Steele L, Greathouse K, Anglim L, Hanson-Huber L, Nateri J, Nicol K, Hall MW, Ramilo O, Muszynski JA. Shock Severity Modifies Associations Between RBC Transfusion in the First 48 Hours of Sepsis Onset and the Duration of Organ Dysfunction in Critically Ill Septic Children. Pediatr Crit Care Med. 2020 Aug; 21: e475-e484.
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 Aug; 48: 1120-1128.
Hall MW, Joshi I, Leal L, Ooi EE. Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention. Clin Infect Dis. 2020 Jul 1;
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 May 11;
Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, Heidemann SM, Kleinman LC, Sen AI, Hall MW, Priestley MA, McGuire JK, Boukas K, Sharron MP, Burns JP, International COVID-19 PICU Collaborative.. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. 2020 May 11;
Sribnick EA, Hensley J, Moore-Clingenpeel M, Muszynski JA, Thakkar RK, Hall MW. Nosocomial Infection Following Severe Traumatic Injury in Children. Pediatr Crit Care Med. 2020 May; 21: 443-450.
Gertz SJ, McArthur J, Hsing DD, Nitu ME, Smith LS, Loomis A, Fitzgerald JC, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Cheifetz IM, Rowan CM, Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network.. Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant. Transpl Infect Dis. 2020 Apr 19; e13297.
Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Apr 21;
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 329-337.
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 319-328.
Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators.. RIG-I and TLR4 Responses and Adverse Outcomes in Pediatric Influenza-Related Critical Illness. J Allergy Clin Immunol. 2020 Feb 5;
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: e52-e106.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: 186-195.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 Feb; 46: 10-67.
Sribnick EA, Weber MD, Hall MW. Innate immune suppression after traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma. J Neuroimmunol. 2019 Dec 15; 337: 577073.
Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure. Pediatr Crit Care Med. 2019 Sep 18;
La Count S, Lovett ME, Zhao S, Kline D, O'Brien NF, Hall MW, Sribnick EA. Factors Associated With Poor Outcome in Pediatric Near-Hanging Injuries. J Emerg Med. 2019 Jul; 57: 21-28.
Hungerford JL, O'Brien N, Moore-Clingenpeel M, Sribnick EA, Sargel C, Hall M, Leonard JR, Tobias JD. Remifentanil for Sedation of Children With Traumatic Brain Injury. J Intensive Care Med. 2019 Jul; 34: 557-562.
Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Zuppa AF, Graham K, Twelves C, Diliberto MA, Landis WP, Tomanio E, Kwok J, Bell MJ, Abraham A, Sapru A, Alkhouli MF, Heidemann S, Pawluszka A, Hall MW, Steele L, Shanley TP, Weber M, Dalton HJ, Bell A, Mourani PM, Malone K, Locandro C, Coleman W, Peterson A, Thelen J, Doctor A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators.. The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation. 2019 Jun 6; 141: 88-95.
Thakkar RK, Weiss SL, Fitzgerald JC, Keele L, Thomas NJ, Nadkarni VM, Muszynski JA, Hall MW, SPROUT Investigators., Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis. J Surg Res. 2019 May 7; 242: 100-110.
Hall MW. Immune Modulation in Pediatric Sepsis. J Pediatr Intensive Care. 2019 Mar; 8: 42-50.
Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, Han Y, Easley KA, Knezevic A, Dai T, Paden M, Carcillo JA, Thrombocytopenia-Associated Multiple Organ Failure (TAMOF) Network Study Group.. Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience. Crit Care Med. 2019 Mar; 47: e173-e181.
Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, PALISI PICFLU Investigators., Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10: 1005.
Karsies T, Moore-Clingenpeel M, Hall M. Development and Validation of a Model to Predict Growth of Potentially Antibiotic-Resistant Gram-Negative Bacilli in Critically Ill Children With Suspected Infection. Open Forum Infect Dis. 2018 Nov; 5: ofy278.
Rowan CM, McArthur J, Hsing DD, Gertz SJ, Smith LS, Loomis A, Fitzgerald JC, Nitu ME, Moser EAS, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. Acute Respiratory Failure in Pediatric Hematopoietic Cell Transplantation: A Multicenter Study. Crit Care Med. 2018 Oct; 46: e967-e974.
Stenson EK, Cvijanovich NZ, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Jain PN, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Wong HR, Anas N. Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock. Intensive Care Med. 2018 Oct 15;
Willson DF, Hall M, Beardsley A, Hoot M, Kirby A, Hays S, Erickson S, Truemper E, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Pediatric Ventilator-Associated Events: Analysis of the Pediatric Ventilator-Associated Infection Data. Pediatr Crit Care Med. 2018 Sep 18;
Muszynski JA, Nofziger R, Moore-Clingenpeel M, Greathouse K, Anglim L, Steele L, Hensley J, Hanson-Huber L, Nateri J, Ramilo O, Hall MW. Early Immune Function and Duration of Organ Dysfunction in Critically III Children with Sepsis. Am J Respir Crit Care Med. 2018 Aug 1; 198: 361-369.
Thakkar RK, Diltz Z, Drews JD, Wheeler KK, Shi J, Devine R, Fabia R, Hall M. Abnormal lymphocyte response after pediatric thermal injury is associated with adverse outcomes. J Surg Res. 2018 Aug; 228: 221-227.
Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt K, Pediatric Intensive Care Influenza (PICFLU) Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network.. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children with Influenza-Related Critical Illness. Clin Infect Dis. 2018 Jun 9;
Rowan CM, Loomis A, McArthur J, Smith LS, Gertz SJ, Fitzgerald JC, Nitu ME, Moser EA, Hsing DD, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient. Respir Care. 2018 Apr; 63: 404-411.
Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR. Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. Pediatr Crit Care Med. 2018 Feb; 19: 155-160.
Devine RA, Diltz Z, Hall MW, Thakkar RK. The systemic immune response to pediatric thermal injury. Int J Burns Trauma. 2018; 8: 6-16.
Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK. The Functional Immune Response of Patients on Extracorporeal Life Support. ASAIO J. 2018 Jan 10;
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Center for Clinical and Translational Research
The Immune Surveillance Laboratory at The Research institute at Nationwide Children’s Hospital is a high-throughput clinical and translational research laboratory dedicated to understanding the immune response to critical illness. The laboratory provides immune function testing services for single- and multi-center studies of immune function in critically ill children across North America. Publications
Berg RA, Morgan RW, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM. Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study. Crit Care Med. 2023 Jan 1; 51: 91-102.
Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Michael Dean J, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, KirkpatrickN T, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, NaimCE MY, Notterman D, Page K, Pollack MM, Qunibi D, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Calcium Use during Paediatric In-hospital Cardiac Arrest is Associated with Worse Outcomes. Resuscitation. 2022 Dec 21; 109673.
Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC Jr, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators. Association of Asthma with Treatments and Outcomes in Children with Critical Influenza. J Allergy Clin Immunol Pract. 2022 Nov 12;
LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS Jr, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2022 Nov 7;
Ross CE, Burns JP, Grossestreuer AV, Bhattarai P, McKiernan CA, Franks JD, Lehmann S, Sorcher JL, Sharron MP, Wai K, Al-Wahab H, Boukas K, Hall MW, Ru G, Sen AI, Rajasekhar HR, Kleinman LC, McGuire JK, Arrington AS, Munoz-Rivas F, Osborne CM, Shekerdemian LS. Trends in Disease Severity Among Critically Ill Children With Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Multicenter Cohort Study in the United States. Pediatr Crit Care Med. 2022 Nov 17;
Horvat CM, Fabio A, Nagin DS, Banks RK, Qin Y, Park HJ, Kernan KF, Canna SW, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Sward K, Holubkov R, Notterman DA, Dean JM, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels. Pediatr Crit Care Med. 2022 Sep 30;
Zambrano LD, Ly KN, Link-Gelles R, Newhams MM, Akande M, Wu MJ, Feldstein LR, Tarquinio KM, Sahni LC, Riggs BJ, Singh AR, Fitzgerald JC, Schuster JE, Giuliano JS Jr, Englund JA, Hume JR, Hall MW, Osborne CM, Doymaz S, Rowan CM, Babbitt CJ, Clouser KN, Horwitz SM, Chou J, Patel MM, Hobbs C, Randolph AG, Campbell AP, Overcoming COVID-19 Investigators.. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. Pediatr Infect Dis J. 2022 Sep 7;
Bline KE, Muszynski JA, Guess AJ, Menocha S, Moore-Clingenpeel MD, Popelka JK, Hensley JM, Steele LM, Goldthwaite IC, Jedreski KJ, Hall MW. Novel Identification of Myeloid-Derived Suppressor Cells in Children With Septic Shock. Pediatr Crit Care Med. 2022 Sep 8;
Morgan RW, Wolfe HA, Reeder RW, Alvey JS, Frazier AH, Friess SH, Maa T, McQuillen PS, Meert KL, Nadkarni VM, Sharron MP, Siems A, Yates AR, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Hall M, Hehir D, Horvat CM, Huard LL, Manga A, Mourani PM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa AF, Berg RA, Sutton RM. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022 Sep 2;
Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFlu) Investigators and the TOPMed Investigators.. DDX58 is Associated with Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 Aug 20;
Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host respiratory transcriptome signature associated with poor outcome in children with influenza-Staphylococcus aureus pneumonia. J Infect Dis. 2022 Jul 28;
Cashen K, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators.. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 Jul 26;
Morin L, Hall M, de Souza D, Guoping L, Jabornisky R, Shime N, Ranjit S, Gilholm P, Nakagawa S, Zimmerman JJ, Sorce LR, Argent A, Kissoon N, Tissières P, Watson RS, Schlapbach LJ, Pediatric Sepsis Definition Taskforce.. The Current and Future State of Pediatric Sepsis Definitions: An International Survey. Pediatrics. 2022 Jun 1; 149:
Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Soma VL, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG, Pediatric Intensive Care Influenza., Overcoming COVID-19 Investigators.. Life-Threatening Complications of Influenza versus COVID-19 in U.S. Children. Clin Infect Dis. 2022 Jun 19;
Salud D, Reeder RW, Banks RK, Meert KL, Berg RA, Zuppa A, Newth CJ, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Varni JW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med. 2022 Jun 10;
Qin Y, Kernan KF, Fan Z, Park HJ, Kim S, Canna SW, Kellum JA, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Michael Dean J, Carcillo JA. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 May 7; 26: 128.
Ames SG, Banks RK, Zinter MS, Fink EL, McQuillen PS, Hall MW, Zuppa A, Meert KL, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Berg RA, Mareboina M, Holubkov R, Dean JM, Notterman DA, Sapru A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2022 Apr 22;
Thakkar RK, Penatzer J, Simon S, Steele L, Fabia R, Groner JI, Keesari R, Hall M. Measures of Adaptive Immune Function Predict the Risk of Nosocomial Infection in Pediatric Burn Patients. J Burn Care Res. 2022 Apr 18;
Tsitsiklis A, Osborne CM, Kamm J, Williamson K, Kalantar K, Dudas G, Caldera S, Lyden A, Tan M, Neff N, Soesanto V, Harris JK, Ambroggio L, Maddux AB, Carpenter TC, Reeder RW, Locandro C, Simões EAF, Leroue MK, Hall MW, Zuppa AF, Carcillo J, Meert KL, Sapru A, Pollack MM, McQuillen PS, Notterman DA, Dean JM, Zinter MS, Wagner BD, DeRisi JL, Mourani PM, Langelier CR. Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics. Lancet Microbe. 2022 Apr; 3: e284-e293.
ICU-RESUS and Eunice Kennedy Shriver National Institute of Child Health., Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups., Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bishop R, Bochkoris M, Burns C, Diddle JW, Federman M, Fernandez R, Franzon D, Frazier AH, Friess SH, Graham K, Hehir D, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Schneiter C, Sharron MP, Siems A, Srivastava N, Tabbutt S, Tilford B, Viteri S, Berg RA, Bell MJ, Carcillo JA, Carpenter TC, Dean JM, Fink EL, Hall M, McQuillen PS, Meert KL, Mourani PM, Notterman D, Pollack MM, Sapru A, Wessel D, Yates AR, Zuppa AF. Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial. JAMA. 2022 Mar 8; 327: 934-945.
Yates AR, Berger JT, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Notterman DA, Holubkov R, Dean JM, Wessel DL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients. Pediatr Crit Care Med. 2022 Feb 23;
Farhat MH, Shadley JD, Halligan NLN, Hall MW, Popova AP, Quasney MW, Dahmer MK. Differences in the Genomic Profiles of Immunoparalyzed and Nonimmunoparalyzed Children With Sepsis: A Pilot Study. Pediatr Crit Care Med. 2022 Feb 1; 23: 79-88.
Sribnick EA, Popovich PG, Hall MW. Central nervous system injury-induced immune suppression. Neurosurg Focus. 2022 Feb; 52: E10.
Olson SM, Newhams MM, Halasa NB, Feldstein LR, Novak T, Weiss SL, Coates BM, Schuster JE, Schwarz AJ, Maddux AB, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Stewart LS, Barnes JR, Patel MM, Randolph AG, Pediatric Intensive Care Influenza Investigators .. Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. Clin Infect Dis. 2022 Jan 13;
Schuster JE, Halasa NB, Nakamura M, Levy ER, Fitzgerald JC, Young CC, Newhams MM, Bourgeois F, Staat MA, Hobbs CV, Dapul H, Feldstein LR, Jackson AM, Mack EH, Walker TC, Maddux AB, Spinella PC, Loftis LL, Kong M, Rowan CM, Bembea MM, McLaughlin GE, Hall MW, Babbitt CJ, Maamari M, Zinter MS, Cvijanovich NZ, Michelson KN, Gertz SJ, Carroll CL, Thomas NJ, Giuliano JS, Singh AR, Hymes SR, Schwarz AJ, McGuire JK, Nofziger RA, Flori HR, Clouser KN, Wellnitz K, Cullimore ML, Hume JR, Patel M, Randolph AG, Overcoming COVID-19 Investigators.. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 Jan 12;
Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo JA. Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis. J Clin Immunol. 2022 Jan 1;
Hall MW, Carcillo JA, Cornell T, Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative.. Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022 Jan 1; 149: S91-S98.
Bembea MM, Agus M, Akcan-Arikan A, Alexander P, Basu R, Bennett TD, Bohn D, Brandão LR, Brown AM, Carcillo JA, Checchia P, Cholette J, Cheifetz IM, Cornell T, Doctor A, Eckerle M, Erickson S, Farris RWD, Faustino EVS, Fitzgerald JC, Fuhrman DY, Giuliano JS, Guilliams K, Gaies M, Gorga SM, Hall M, Hanson SJ, Hartman M, Hassinger AB, Irving SY, Jeffries H, Jouvet P, Kannan S, Karam O, Khemani RG, Kissoon N, Lacroix J, Laussen P, Leclerc F, Lee JH, Leteurtre S, Lobner K, McKiernan PJ, Menon K, Monagle P, Muszynski JA, Odetola F, Parker R, Pathan N, Pierce RW, Pineda J, Prince JM, Robinson KA, Rowan CM, Ryerson LM, Sanchez-Pinto LN, Schlapbach LJ, Selewski DT, Shekerdemian LS, Simon D, Smith LS, Squires JE, Squires RH, Sutherland SM, Ouellette Y, Spaeder MC, Srinivasan V, Steiner ME, Tasker RC, Thiagarajan R, Thomas N, Tissieres P, Traube C, Tucci M, Typpo KV, Wainwright MS, Ward SL, Watson RS, Weiss S, Whitney J, Willson D, Wynn JL, Yeyha N, Zimmerman JJ. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics. 2022 Jan 1; 149: S1-S12.
Muszynski JA, Banks R, Reeder RW, Hall MW, Berg RA, Zuppa A, Shanley TP, Cornell TT, Newth CJL, Pollack MM, Wessel D, Doctor A, Lin JC, Harrison RE, Meert KL, Dean JM, Holubkov R, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Outcomes Associated With Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study. Shock. 2022 Jan 1; 57: 88-94.
Mertz C, Glowinski R, Cohen SH, Mertz S, Ye F, Hall MW, Peeples ME, King T, Wang H, Leber AL, Sanchez PJ, Ramilo O, Mejias A. Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019. J Infect Dis. 2022 Jan 18; 225: 208-213.
Mukherjee R, Tompkins CA, Ostberg NP, Joshi AU, Massis LM, Vijayan V, Gera K, Monack D, Cornell TT, Hall MW, Mochly-Rosen D, Haileselassie B. Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance. Crit Care Med. 2022 Jan 24;
Penatzer JA, Alexander R, Simon S, Wolfe A, Breuer J, Hensley J, Fabia R, Hall M, Thakkar RK. Early detection of soluble CD27, BTLA, and TIM-3 predicts the development of nosocomial infection in pediatric burn patients. Front Immunol. 2022; 13: 940835.
Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2021 Dec 21;
Sribnick EA, Warner T, Hall MW. Traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma leads to immunosuppression and splenic alterations. J Neuroimmunol. 2021 Dec 15; 361: 577723.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Notterman DA, Colville G, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Post-Traumatic Growth in Parents following Their Child's Death in a Pediatric Intensive Care Unit. J Palliat Med. 2021 Oct 5;
Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, Overcoming COVID-19 Investigators.. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40: 101112.
Bline KE, Hall MW. Immune Function in Critically Ill Septic Children. Pathogens. 2021 Sep 25; 10:
Diaz-Diaz A, Bunsow E, Garcia-Maurino C, Moore-Clingenpeel M, Naples J, Juergensen A, Mertz S, Wang H, Leber AL, Gern J, Hall MW, Cohen DM, Ramilo O, Mejias A. Nasopharyngeal Codetection of H. influenzae and S. pneumoniae and Respiratory Syncytial Virus Disease Outcomes in Children. J Infect Dis. 2021 Sep 20;
Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators., Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates AR. Factors Associated With Functional Impairment After Pediatric Injury. JAMA Surg. 2021 Aug 1; 156: e212058.
Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS Jr, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 Jul 1; 385: 23-34.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Complicated Grief, Depression and Post-Traumatic Stress Symptoms Among Bereaved Parents following their Child's Death in the Pediatric Intensive Care Unit: A Follow-Up Study. Am J Hosp Palliat Care. 2021 May 5; 10499091211015913.
Snyder A, Jedreski K, Fitch J, Wijeratne S, Wetzel A, Hensley J, Flowers M, Bline K, Hall MW, Muszynski JA. Transcriptomic Profiles in Children With Septic Shock With or Without Immunoparalysis. Front Immunol. 2021; 12: 733834.
Pinto NP, Berg RA, Zuppa AF, Newth CJ, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Nadkarni VM, Reeder RW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Front Pediatr. 2021; 9: 675374.
Srouji LS, Moore-Clingenpeel M, Hensley J, Steele L, Greathouse K, Anglim L, Hanson-Huber L, Nateri J, Nicol K, Hall MW, Ramilo O, Muszynski JA. Shock Severity Modifies Associations Between RBC Transfusion in the First 48 Hours of Sepsis Onset and the Duration of Organ Dysfunction in Critically Ill Septic Children. Pediatr Crit Care Med. 2020 Aug; 21: e475-e484.
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 Aug; 48: 1120-1128.
Hall MW, Joshi I, Leal L, Ooi EE. Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention. Clin Infect Dis. 2020 Jul 1;
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 May 11;
Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, Heidemann SM, Kleinman LC, Sen AI, Hall MW, Priestley MA, McGuire JK, Boukas K, Sharron MP, Burns JP, International COVID-19 PICU Collaborative.. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. 2020 May 11;
Sribnick EA, Hensley J, Moore-Clingenpeel M, Muszynski JA, Thakkar RK, Hall MW. Nosocomial Infection Following Severe Traumatic Injury in Children. Pediatr Crit Care Med. 2020 May; 21: 443-450.
Gertz SJ, McArthur J, Hsing DD, Nitu ME, Smith LS, Loomis A, Fitzgerald JC, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Cheifetz IM, Rowan CM, Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network.. Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant. Transpl Infect Dis. 2020 Apr 19; e13297.
Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Apr 21;
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 329-337.
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 319-328.
Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators.. RIG-I and TLR4 Responses and Adverse Outcomes in Pediatric Influenza-Related Critical Illness. J Allergy Clin Immunol. 2020 Feb 5;
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: e52-e106.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: 186-195.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 Feb; 46: 10-67.
Sribnick EA, Weber MD, Hall MW. Innate immune suppression after traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma. J Neuroimmunol. 2019 Dec 15; 337: 577073.
Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure. Pediatr Crit Care Med. 2019 Sep 18;
La Count S, Lovett ME, Zhao S, Kline D, O'Brien NF, Hall MW, Sribnick EA. Factors Associated With Poor Outcome in Pediatric Near-Hanging Injuries. J Emerg Med. 2019 Jul; 57: 21-28.
Hungerford JL, O'Brien N, Moore-Clingenpeel M, Sribnick EA, Sargel C, Hall M, Leonard JR, Tobias JD. Remifentanil for Sedation of Children With Traumatic Brain Injury. J Intensive Care Med. 2019 Jul; 34: 557-562.
Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Zuppa AF, Graham K, Twelves C, Diliberto MA, Landis WP, Tomanio E, Kwok J, Bell MJ, Abraham A, Sapru A, Alkhouli MF, Heidemann S, Pawluszka A, Hall MW, Steele L, Shanley TP, Weber M, Dalton HJ, Bell A, Mourani PM, Malone K, Locandro C, Coleman W, Peterson A, Thelen J, Doctor A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators.. The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation. 2019 Jun 6; 141: 88-95.
Thakkar RK, Weiss SL, Fitzgerald JC, Keele L, Thomas NJ, Nadkarni VM, Muszynski JA, Hall MW, SPROUT Investigators., Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis. J Surg Res. 2019 May 7; 242: 100-110.
Hall MW. Immune Modulation in Pediatric Sepsis. J Pediatr Intensive Care. 2019 Mar; 8: 42-50.
Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, Han Y, Easley KA, Knezevic A, Dai T, Paden M, Carcillo JA, Thrombocytopenia-Associated Multiple Organ Failure (TAMOF) Network Study Group.. Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience. Crit Care Med. 2019 Mar; 47: e173-e181.
Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, PALISI PICFLU Investigators., Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10: 1005.
Karsies T, Moore-Clingenpeel M, Hall M. Development and Validation of a Model to Predict Growth of Potentially Antibiotic-Resistant Gram-Negative Bacilli in Critically Ill Children With Suspected Infection. Open Forum Infect Dis. 2018 Nov; 5: ofy278.
Rowan CM, McArthur J, Hsing DD, Gertz SJ, Smith LS, Loomis A, Fitzgerald JC, Nitu ME, Moser EAS, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. Acute Respiratory Failure in Pediatric Hematopoietic Cell Transplantation: A Multicenter Study. Crit Care Med. 2018 Oct; 46: e967-e974.
Stenson EK, Cvijanovich NZ, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Jain PN, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Wong HR, Anas N. Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock. Intensive Care Med. 2018 Oct 15;
Willson DF, Hall M, Beardsley A, Hoot M, Kirby A, Hays S, Erickson S, Truemper E, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Pediatric Ventilator-Associated Events: Analysis of the Pediatric Ventilator-Associated Infection Data. Pediatr Crit Care Med. 2018 Sep 18;
Muszynski JA, Nofziger R, Moore-Clingenpeel M, Greathouse K, Anglim L, Steele L, Hensley J, Hanson-Huber L, Nateri J, Ramilo O, Hall MW. Early Immune Function and Duration of Organ Dysfunction in Critically III Children with Sepsis. Am J Respir Crit Care Med. 2018 Aug 1; 198: 361-369.
Thakkar RK, Diltz Z, Drews JD, Wheeler KK, Shi J, Devine R, Fabia R, Hall M. Abnormal lymphocyte response after pediatric thermal injury is associated with adverse outcomes. J Surg Res. 2018 Aug; 228: 221-227.
Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt K, Pediatric Intensive Care Influenza (PICFLU) Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network.. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children with Influenza-Related Critical Illness. Clin Infect Dis. 2018 Jun 9;
Rowan CM, Loomis A, McArthur J, Smith LS, Gertz SJ, Fitzgerald JC, Nitu ME, Moser EA, Hsing DD, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient. Respir Care. 2018 Apr; 63: 404-411.
Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR. Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. Pediatr Crit Care Med. 2018 Feb; 19: 155-160.
Devine RA, Diltz Z, Hall MW, Thakkar RK. The systemic immune response to pediatric thermal injury. Int J Burns Trauma. 2018; 8: 6-16.
Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK. The Functional Immune Response of Patients on Extracorporeal Life Support. ASAIO J. 2018 Jan 10;
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Center for Clinical and Translational Research
The Immune Surveillance Laboratory at The Research institute at Nationwide Children’s Hospital is a high-throughput clinical and translational research laboratory dedicated to understanding the immune response to critical illness. The laboratory provides immune function testing services for single- and multi-center studies of immune function in critically ill children across North America. Publications
Berg RA, Morgan RW, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM. Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study. Crit Care Med. 2023 Jan 1; 51: 91-102.
Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Michael Dean J, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, KirkpatrickN T, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, NaimCE MY, Notterman D, Page K, Pollack MM, Qunibi D, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Calcium Use during Paediatric In-hospital Cardiac Arrest is Associated with Worse Outcomes. Resuscitation. 2022 Dec 21; 109673.
Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC Jr, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators. Association of Asthma with Treatments and Outcomes in Children with Critical Influenza. J Allergy Clin Immunol Pract. 2022 Nov 12;
LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS Jr, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2022 Nov 7;
Ross CE, Burns JP, Grossestreuer AV, Bhattarai P, McKiernan CA, Franks JD, Lehmann S, Sorcher JL, Sharron MP, Wai K, Al-Wahab H, Boukas K, Hall MW, Ru G, Sen AI, Rajasekhar HR, Kleinman LC, McGuire JK, Arrington AS, Munoz-Rivas F, Osborne CM, Shekerdemian LS. Trends in Disease Severity Among Critically Ill Children With Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Multicenter Cohort Study in the United States. Pediatr Crit Care Med. 2022 Nov 17;
Horvat CM, Fabio A, Nagin DS, Banks RK, Qin Y, Park HJ, Kernan KF, Canna SW, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Sward K, Holubkov R, Notterman DA, Dean JM, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels. Pediatr Crit Care Med. 2022 Sep 30;
Zambrano LD, Ly KN, Link-Gelles R, Newhams MM, Akande M, Wu MJ, Feldstein LR, Tarquinio KM, Sahni LC, Riggs BJ, Singh AR, Fitzgerald JC, Schuster JE, Giuliano JS Jr, Englund JA, Hume JR, Hall MW, Osborne CM, Doymaz S, Rowan CM, Babbitt CJ, Clouser KN, Horwitz SM, Chou J, Patel MM, Hobbs C, Randolph AG, Campbell AP, Overcoming COVID-19 Investigators.. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. Pediatr Infect Dis J. 2022 Sep 7;
Bline KE, Muszynski JA, Guess AJ, Menocha S, Moore-Clingenpeel MD, Popelka JK, Hensley JM, Steele LM, Goldthwaite IC, Jedreski KJ, Hall MW. Novel Identification of Myeloid-Derived Suppressor Cells in Children With Septic Shock. Pediatr Crit Care Med. 2022 Sep 8;
Morgan RW, Wolfe HA, Reeder RW, Alvey JS, Frazier AH, Friess SH, Maa T, McQuillen PS, Meert KL, Nadkarni VM, Sharron MP, Siems A, Yates AR, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Hall M, Hehir D, Horvat CM, Huard LL, Manga A, Mourani PM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa AF, Berg RA, Sutton RM. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022 Sep 2;
Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFlu) Investigators and the TOPMed Investigators.. DDX58 is Associated with Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 Aug 20;
Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host respiratory transcriptome signature associated with poor outcome in children with influenza-Staphylococcus aureus pneumonia. J Infect Dis. 2022 Jul 28;
Cashen K, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators.. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 Jul 26;
Morin L, Hall M, de Souza D, Guoping L, Jabornisky R, Shime N, Ranjit S, Gilholm P, Nakagawa S, Zimmerman JJ, Sorce LR, Argent A, Kissoon N, Tissières P, Watson RS, Schlapbach LJ, Pediatric Sepsis Definition Taskforce.. The Current and Future State of Pediatric Sepsis Definitions: An International Survey. Pediatrics. 2022 Jun 1; 149:
Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Soma VL, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG, Pediatric Intensive Care Influenza., Overcoming COVID-19 Investigators.. Life-Threatening Complications of Influenza versus COVID-19 in U.S. Children. Clin Infect Dis. 2022 Jun 19;
Salud D, Reeder RW, Banks RK, Meert KL, Berg RA, Zuppa A, Newth CJ, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Varni JW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med. 2022 Jun 10;
Qin Y, Kernan KF, Fan Z, Park HJ, Kim S, Canna SW, Kellum JA, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Michael Dean J, Carcillo JA. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 May 7; 26: 128.
Ames SG, Banks RK, Zinter MS, Fink EL, McQuillen PS, Hall MW, Zuppa A, Meert KL, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Berg RA, Mareboina M, Holubkov R, Dean JM, Notterman DA, Sapru A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2022 Apr 22;
Thakkar RK, Penatzer J, Simon S, Steele L, Fabia R, Groner JI, Keesari R, Hall M. Measures of Adaptive Immune Function Predict the Risk of Nosocomial Infection in Pediatric Burn Patients. J Burn Care Res. 2022 Apr 18;
Tsitsiklis A, Osborne CM, Kamm J, Williamson K, Kalantar K, Dudas G, Caldera S, Lyden A, Tan M, Neff N, Soesanto V, Harris JK, Ambroggio L, Maddux AB, Carpenter TC, Reeder RW, Locandro C, Simões EAF, Leroue MK, Hall MW, Zuppa AF, Carcillo J, Meert KL, Sapru A, Pollack MM, McQuillen PS, Notterman DA, Dean JM, Zinter MS, Wagner BD, DeRisi JL, Mourani PM, Langelier CR. Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics. Lancet Microbe. 2022 Apr; 3: e284-e293.
ICU-RESUS and Eunice Kennedy Shriver National Institute of Child Health., Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups., Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bishop R, Bochkoris M, Burns C, Diddle JW, Federman M, Fernandez R, Franzon D, Frazier AH, Friess SH, Graham K, Hehir D, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Schneiter C, Sharron MP, Siems A, Srivastava N, Tabbutt S, Tilford B, Viteri S, Berg RA, Bell MJ, Carcillo JA, Carpenter TC, Dean JM, Fink EL, Hall M, McQuillen PS, Meert KL, Mourani PM, Notterman D, Pollack MM, Sapru A, Wessel D, Yates AR, Zuppa AF. Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial. JAMA. 2022 Mar 8; 327: 934-945.
Yates AR, Berger JT, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Notterman DA, Holubkov R, Dean JM, Wessel DL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients. Pediatr Crit Care Med. 2022 Feb 23;
Farhat MH, Shadley JD, Halligan NLN, Hall MW, Popova AP, Quasney MW, Dahmer MK. Differences in the Genomic Profiles of Immunoparalyzed and Nonimmunoparalyzed Children With Sepsis: A Pilot Study. Pediatr Crit Care Med. 2022 Feb 1; 23: 79-88.
Sribnick EA, Popovich PG, Hall MW. Central nervous system injury-induced immune suppression. Neurosurg Focus. 2022 Feb; 52: E10.
Olson SM, Newhams MM, Halasa NB, Feldstein LR, Novak T, Weiss SL, Coates BM, Schuster JE, Schwarz AJ, Maddux AB, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Stewart LS, Barnes JR, Patel MM, Randolph AG, Pediatric Intensive Care Influenza Investigators .. Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. Clin Infect Dis. 2022 Jan 13;
Schuster JE, Halasa NB, Nakamura M, Levy ER, Fitzgerald JC, Young CC, Newhams MM, Bourgeois F, Staat MA, Hobbs CV, Dapul H, Feldstein LR, Jackson AM, Mack EH, Walker TC, Maddux AB, Spinella PC, Loftis LL, Kong M, Rowan CM, Bembea MM, McLaughlin GE, Hall MW, Babbitt CJ, Maamari M, Zinter MS, Cvijanovich NZ, Michelson KN, Gertz SJ, Carroll CL, Thomas NJ, Giuliano JS, Singh AR, Hymes SR, Schwarz AJ, McGuire JK, Nofziger RA, Flori HR, Clouser KN, Wellnitz K, Cullimore ML, Hume JR, Patel M, Randolph AG, Overcoming COVID-19 Investigators.. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 Jan 12;
Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo JA. Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis. J Clin Immunol. 2022 Jan 1;
Hall MW, Carcillo JA, Cornell T, Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative.. Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022 Jan 1; 149: S91-S98.
Bembea MM, Agus M, Akcan-Arikan A, Alexander P, Basu R, Bennett TD, Bohn D, Brandão LR, Brown AM, Carcillo JA, Checchia P, Cholette J, Cheifetz IM, Cornell T, Doctor A, Eckerle M, Erickson S, Farris RWD, Faustino EVS, Fitzgerald JC, Fuhrman DY, Giuliano JS, Guilliams K, Gaies M, Gorga SM, Hall M, Hanson SJ, Hartman M, Hassinger AB, Irving SY, Jeffries H, Jouvet P, Kannan S, Karam O, Khemani RG, Kissoon N, Lacroix J, Laussen P, Leclerc F, Lee JH, Leteurtre S, Lobner K, McKiernan PJ, Menon K, Monagle P, Muszynski JA, Odetola F, Parker R, Pathan N, Pierce RW, Pineda J, Prince JM, Robinson KA, Rowan CM, Ryerson LM, Sanchez-Pinto LN, Schlapbach LJ, Selewski DT, Shekerdemian LS, Simon D, Smith LS, Squires JE, Squires RH, Sutherland SM, Ouellette Y, Spaeder MC, Srinivasan V, Steiner ME, Tasker RC, Thiagarajan R, Thomas N, Tissieres P, Traube C, Tucci M, Typpo KV, Wainwright MS, Ward SL, Watson RS, Weiss S, Whitney J, Willson D, Wynn JL, Yeyha N, Zimmerman JJ. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics. 2022 Jan 1; 149: S1-S12.
Muszynski JA, Banks R, Reeder RW, Hall MW, Berg RA, Zuppa A, Shanley TP, Cornell TT, Newth CJL, Pollack MM, Wessel D, Doctor A, Lin JC, Harrison RE, Meert KL, Dean JM, Holubkov R, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Outcomes Associated With Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study. Shock. 2022 Jan 1; 57: 88-94.
Mertz C, Glowinski R, Cohen SH, Mertz S, Ye F, Hall MW, Peeples ME, King T, Wang H, Leber AL, Sanchez PJ, Ramilo O, Mejias A. Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019. J Infect Dis. 2022 Jan 18; 225: 208-213.
Mukherjee R, Tompkins CA, Ostberg NP, Joshi AU, Massis LM, Vijayan V, Gera K, Monack D, Cornell TT, Hall MW, Mochly-Rosen D, Haileselassie B. Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance. Crit Care Med. 2022 Jan 24;
Penatzer JA, Alexander R, Simon S, Wolfe A, Breuer J, Hensley J, Fabia R, Hall M, Thakkar RK. Early detection of soluble CD27, BTLA, and TIM-3 predicts the development of nosocomial infection in pediatric burn patients. Front Immunol. 2022; 13: 940835.
Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2021 Dec 21;
Sribnick EA, Warner T, Hall MW. Traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma leads to immunosuppression and splenic alterations. J Neuroimmunol. 2021 Dec 15; 361: 577723.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Notterman DA, Colville G, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Post-Traumatic Growth in Parents following Their Child's Death in a Pediatric Intensive Care Unit. J Palliat Med. 2021 Oct 5;
Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, Overcoming COVID-19 Investigators.. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40: 101112.
Bline KE, Hall MW. Immune Function in Critically Ill Septic Children. Pathogens. 2021 Sep 25; 10:
Diaz-Diaz A, Bunsow E, Garcia-Maurino C, Moore-Clingenpeel M, Naples J, Juergensen A, Mertz S, Wang H, Leber AL, Gern J, Hall MW, Cohen DM, Ramilo O, Mejias A. Nasopharyngeal Codetection of H. influenzae and S. pneumoniae and Respiratory Syncytial Virus Disease Outcomes in Children. J Infect Dis. 2021 Sep 20;
Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators., Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates AR. Factors Associated With Functional Impairment After Pediatric Injury. JAMA Surg. 2021 Aug 1; 156: e212058.
Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS Jr, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 Jul 1; 385: 23-34.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Complicated Grief, Depression and Post-Traumatic Stress Symptoms Among Bereaved Parents following their Child's Death in the Pediatric Intensive Care Unit: A Follow-Up Study. Am J Hosp Palliat Care. 2021 May 5; 10499091211015913.
Snyder A, Jedreski K, Fitch J, Wijeratne S, Wetzel A, Hensley J, Flowers M, Bline K, Hall MW, Muszynski JA. Transcriptomic Profiles in Children With Septic Shock With or Without Immunoparalysis. Front Immunol. 2021; 12: 733834.
Pinto NP, Berg RA, Zuppa AF, Newth CJ, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Nadkarni VM, Reeder RW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Front Pediatr. 2021; 9: 675374.
Srouji LS, Moore-Clingenpeel M, Hensley J, Steele L, Greathouse K, Anglim L, Hanson-Huber L, Nateri J, Nicol K, Hall MW, Ramilo O, Muszynski JA. Shock Severity Modifies Associations Between RBC Transfusion in the First 48 Hours of Sepsis Onset and the Duration of Organ Dysfunction in Critically Ill Septic Children. Pediatr Crit Care Med. 2020 Aug; 21: e475-e484.
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 Aug; 48: 1120-1128.
Hall MW, Joshi I, Leal L, Ooi EE. Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention. Clin Infect Dis. 2020 Jul 1;
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 May 11;
Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, Heidemann SM, Kleinman LC, Sen AI, Hall MW, Priestley MA, McGuire JK, Boukas K, Sharron MP, Burns JP, International COVID-19 PICU Collaborative.. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. 2020 May 11;
Sribnick EA, Hensley J, Moore-Clingenpeel M, Muszynski JA, Thakkar RK, Hall MW. Nosocomial Infection Following Severe Traumatic Injury in Children. Pediatr Crit Care Med. 2020 May; 21: 443-450.
Gertz SJ, McArthur J, Hsing DD, Nitu ME, Smith LS, Loomis A, Fitzgerald JC, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Cheifetz IM, Rowan CM, Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network.. Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant. Transpl Infect Dis. 2020 Apr 19; e13297.
Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Apr 21;
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 329-337.
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 319-328.
Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators.. RIG-I and TLR4 Responses and Adverse Outcomes in Pediatric Influenza-Related Critical Illness. J Allergy Clin Immunol. 2020 Feb 5;
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: e52-e106.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: 186-195.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 Feb; 46: 10-67.
Sribnick EA, Weber MD, Hall MW. Innate immune suppression after traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma. J Neuroimmunol. 2019 Dec 15; 337: 577073.
Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure. Pediatr Crit Care Med. 2019 Sep 18;
La Count S, Lovett ME, Zhao S, Kline D, O'Brien NF, Hall MW, Sribnick EA. Factors Associated With Poor Outcome in Pediatric Near-Hanging Injuries. J Emerg Med. 2019 Jul; 57: 21-28.
Hungerford JL, O'Brien N, Moore-Clingenpeel M, Sribnick EA, Sargel C, Hall M, Leonard JR, Tobias JD. Remifentanil for Sedation of Children With Traumatic Brain Injury. J Intensive Care Med. 2019 Jul; 34: 557-562.
Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Zuppa AF, Graham K, Twelves C, Diliberto MA, Landis WP, Tomanio E, Kwok J, Bell MJ, Abraham A, Sapru A, Alkhouli MF, Heidemann S, Pawluszka A, Hall MW, Steele L, Shanley TP, Weber M, Dalton HJ, Bell A, Mourani PM, Malone K, Locandro C, Coleman W, Peterson A, Thelen J, Doctor A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators.. The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation. 2019 Jun 6; 141: 88-95.
Thakkar RK, Weiss SL, Fitzgerald JC, Keele L, Thomas NJ, Nadkarni VM, Muszynski JA, Hall MW, SPROUT Investigators., Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis. J Surg Res. 2019 May 7; 242: 100-110.
Hall MW. Immune Modulation in Pediatric Sepsis. J Pediatr Intensive Care. 2019 Mar; 8: 42-50.
Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, Han Y, Easley KA, Knezevic A, Dai T, Paden M, Carcillo JA, Thrombocytopenia-Associated Multiple Organ Failure (TAMOF) Network Study Group.. Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience. Crit Care Med. 2019 Mar; 47: e173-e181.
Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, PALISI PICFLU Investigators., Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10: 1005.
Karsies T, Moore-Clingenpeel M, Hall M. Development and Validation of a Model to Predict Growth of Potentially Antibiotic-Resistant Gram-Negative Bacilli in Critically Ill Children With Suspected Infection. Open Forum Infect Dis. 2018 Nov; 5: ofy278.
Rowan CM, McArthur J, Hsing DD, Gertz SJ, Smith LS, Loomis A, Fitzgerald JC, Nitu ME, Moser EAS, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. Acute Respiratory Failure in Pediatric Hematopoietic Cell Transplantation: A Multicenter Study. Crit Care Med. 2018 Oct; 46: e967-e974.
Stenson EK, Cvijanovich NZ, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Jain PN, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Wong HR, Anas N. Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock. Intensive Care Med. 2018 Oct 15;
Willson DF, Hall M, Beardsley A, Hoot M, Kirby A, Hays S, Erickson S, Truemper E, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Pediatric Ventilator-Associated Events: Analysis of the Pediatric Ventilator-Associated Infection Data. Pediatr Crit Care Med. 2018 Sep 18;
Muszynski JA, Nofziger R, Moore-Clingenpeel M, Greathouse K, Anglim L, Steele L, Hensley J, Hanson-Huber L, Nateri J, Ramilo O, Hall MW. Early Immune Function and Duration of Organ Dysfunction in Critically III Children with Sepsis. Am J Respir Crit Care Med. 2018 Aug 1; 198: 361-369.
Thakkar RK, Diltz Z, Drews JD, Wheeler KK, Shi J, Devine R, Fabia R, Hall M. Abnormal lymphocyte response after pediatric thermal injury is associated with adverse outcomes. J Surg Res. 2018 Aug; 228: 221-227.
Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt K, Pediatric Intensive Care Influenza (PICFLU) Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network.. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children with Influenza-Related Critical Illness. Clin Infect Dis. 2018 Jun 9;
Rowan CM, Loomis A, McArthur J, Smith LS, Gertz SJ, Fitzgerald JC, Nitu ME, Moser EA, Hsing DD, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient. Respir Care. 2018 Apr; 63: 404-411.
Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR. Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. Pediatr Crit Care Med. 2018 Feb; 19: 155-160.
Devine RA, Diltz Z, Hall MW, Thakkar RK. The systemic immune response to pediatric thermal injury. Int J Burns Trauma. 2018; 8: 6-16.
Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK. The Functional Immune Response of Patients on Extracorporeal Life Support. ASAIO J. 2018 Jan 10;
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Lab(s)
Center for Clinical and Translational Research
The Immune Surveillance Laboratory at The Research institute at Nationwide Children’s Hospital is a high-throughput clinical and translational research laboratory dedicated to understanding the immune response to critical illness. The laboratory provides immune function testing services for single- and multi-center studies of immune function in critically ill children across North America. Publications
Berg RA, Morgan RW, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM. Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study. Crit Care Med. 2023 Jan 1; 51: 91-102.
Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Michael Dean J, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, KirkpatrickN T, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, NaimCE MY, Notterman D, Page K, Pollack MM, Qunibi D, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Calcium Use during Paediatric In-hospital Cardiac Arrest is Associated with Worse Outcomes. Resuscitation. 2022 Dec 21; 109673.
Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC Jr, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators. Association of Asthma with Treatments and Outcomes in Children with Critical Influenza. J Allergy Clin Immunol Pract. 2022 Nov 12;
LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS Jr, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2022 Nov 7;
Ross CE, Burns JP, Grossestreuer AV, Bhattarai P, McKiernan CA, Franks JD, Lehmann S, Sorcher JL, Sharron MP, Wai K, Al-Wahab H, Boukas K, Hall MW, Ru G, Sen AI, Rajasekhar HR, Kleinman LC, McGuire JK, Arrington AS, Munoz-Rivas F, Osborne CM, Shekerdemian LS. Trends in Disease Severity Among Critically Ill Children With Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Multicenter Cohort Study in the United States. Pediatr Crit Care Med. 2022 Nov 17;
Horvat CM, Fabio A, Nagin DS, Banks RK, Qin Y, Park HJ, Kernan KF, Canna SW, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Sward K, Holubkov R, Notterman DA, Dean JM, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels. Pediatr Crit Care Med. 2022 Sep 30;
Zambrano LD, Ly KN, Link-Gelles R, Newhams MM, Akande M, Wu MJ, Feldstein LR, Tarquinio KM, Sahni LC, Riggs BJ, Singh AR, Fitzgerald JC, Schuster JE, Giuliano JS Jr, Englund JA, Hume JR, Hall MW, Osborne CM, Doymaz S, Rowan CM, Babbitt CJ, Clouser KN, Horwitz SM, Chou J, Patel MM, Hobbs C, Randolph AG, Campbell AP, Overcoming COVID-19 Investigators.. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. Pediatr Infect Dis J. 2022 Sep 7;
Bline KE, Muszynski JA, Guess AJ, Menocha S, Moore-Clingenpeel MD, Popelka JK, Hensley JM, Steele LM, Goldthwaite IC, Jedreski KJ, Hall MW. Novel Identification of Myeloid-Derived Suppressor Cells in Children With Septic Shock. Pediatr Crit Care Med. 2022 Sep 8;
Morgan RW, Wolfe HA, Reeder RW, Alvey JS, Frazier AH, Friess SH, Maa T, McQuillen PS, Meert KL, Nadkarni VM, Sharron MP, Siems A, Yates AR, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Hall M, Hehir D, Horvat CM, Huard LL, Manga A, Mourani PM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa AF, Berg RA, Sutton RM. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022 Sep 2;
Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFlu) Investigators and the TOPMed Investigators.. DDX58 is Associated with Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 Aug 20;
Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host respiratory transcriptome signature associated with poor outcome in children with influenza-Staphylococcus aureus pneumonia. J Infect Dis. 2022 Jul 28;
Cashen K, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators.. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 Jul 26;
Morin L, Hall M, de Souza D, Guoping L, Jabornisky R, Shime N, Ranjit S, Gilholm P, Nakagawa S, Zimmerman JJ, Sorce LR, Argent A, Kissoon N, Tissières P, Watson RS, Schlapbach LJ, Pediatric Sepsis Definition Taskforce.. The Current and Future State of Pediatric Sepsis Definitions: An International Survey. Pediatrics. 2022 Jun 1; 149:
Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Soma VL, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG, Pediatric Intensive Care Influenza., Overcoming COVID-19 Investigators.. Life-Threatening Complications of Influenza versus COVID-19 in U.S. Children. Clin Infect Dis. 2022 Jun 19;
Salud D, Reeder RW, Banks RK, Meert KL, Berg RA, Zuppa A, Newth CJ, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Varni JW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med. 2022 Jun 10;
Qin Y, Kernan KF, Fan Z, Park HJ, Kim S, Canna SW, Kellum JA, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Michael Dean J, Carcillo JA. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 May 7; 26: 128.
Ames SG, Banks RK, Zinter MS, Fink EL, McQuillen PS, Hall MW, Zuppa A, Meert KL, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Berg RA, Mareboina M, Holubkov R, Dean JM, Notterman DA, Sapru A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2022 Apr 22;
Thakkar RK, Penatzer J, Simon S, Steele L, Fabia R, Groner JI, Keesari R, Hall M. Measures of Adaptive Immune Function Predict the Risk of Nosocomial Infection in Pediatric Burn Patients. J Burn Care Res. 2022 Apr 18;
Tsitsiklis A, Osborne CM, Kamm J, Williamson K, Kalantar K, Dudas G, Caldera S, Lyden A, Tan M, Neff N, Soesanto V, Harris JK, Ambroggio L, Maddux AB, Carpenter TC, Reeder RW, Locandro C, Simões EAF, Leroue MK, Hall MW, Zuppa AF, Carcillo J, Meert KL, Sapru A, Pollack MM, McQuillen PS, Notterman DA, Dean JM, Zinter MS, Wagner BD, DeRisi JL, Mourani PM, Langelier CR. Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics. Lancet Microbe. 2022 Apr; 3: e284-e293.
ICU-RESUS and Eunice Kennedy Shriver National Institute of Child Health., Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups., Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bishop R, Bochkoris M, Burns C, Diddle JW, Federman M, Fernandez R, Franzon D, Frazier AH, Friess SH, Graham K, Hehir D, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Schneiter C, Sharron MP, Siems A, Srivastava N, Tabbutt S, Tilford B, Viteri S, Berg RA, Bell MJ, Carcillo JA, Carpenter TC, Dean JM, Fink EL, Hall M, McQuillen PS, Meert KL, Mourani PM, Notterman D, Pollack MM, Sapru A, Wessel D, Yates AR, Zuppa AF. Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial. JAMA. 2022 Mar 8; 327: 934-945.
Yates AR, Berger JT, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Notterman DA, Holubkov R, Dean JM, Wessel DL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients. Pediatr Crit Care Med. 2022 Feb 23;
Farhat MH, Shadley JD, Halligan NLN, Hall MW, Popova AP, Quasney MW, Dahmer MK. Differences in the Genomic Profiles of Immunoparalyzed and Nonimmunoparalyzed Children With Sepsis: A Pilot Study. Pediatr Crit Care Med. 2022 Feb 1; 23: 79-88.
Sribnick EA, Popovich PG, Hall MW. Central nervous system injury-induced immune suppression. Neurosurg Focus. 2022 Feb; 52: E10.
Olson SM, Newhams MM, Halasa NB, Feldstein LR, Novak T, Weiss SL, Coates BM, Schuster JE, Schwarz AJ, Maddux AB, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Stewart LS, Barnes JR, Patel MM, Randolph AG, Pediatric Intensive Care Influenza Investigators .. Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. Clin Infect Dis. 2022 Jan 13;
Schuster JE, Halasa NB, Nakamura M, Levy ER, Fitzgerald JC, Young CC, Newhams MM, Bourgeois F, Staat MA, Hobbs CV, Dapul H, Feldstein LR, Jackson AM, Mack EH, Walker TC, Maddux AB, Spinella PC, Loftis LL, Kong M, Rowan CM, Bembea MM, McLaughlin GE, Hall MW, Babbitt CJ, Maamari M, Zinter MS, Cvijanovich NZ, Michelson KN, Gertz SJ, Carroll CL, Thomas NJ, Giuliano JS, Singh AR, Hymes SR, Schwarz AJ, McGuire JK, Nofziger RA, Flori HR, Clouser KN, Wellnitz K, Cullimore ML, Hume JR, Patel M, Randolph AG, Overcoming COVID-19 Investigators.. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 Jan 12;
Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo JA. Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis. J Clin Immunol. 2022 Jan 1;
Hall MW, Carcillo JA, Cornell T, Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative.. Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022 Jan 1; 149: S91-S98.
Bembea MM, Agus M, Akcan-Arikan A, Alexander P, Basu R, Bennett TD, Bohn D, Brandão LR, Brown AM, Carcillo JA, Checchia P, Cholette J, Cheifetz IM, Cornell T, Doctor A, Eckerle M, Erickson S, Farris RWD, Faustino EVS, Fitzgerald JC, Fuhrman DY, Giuliano JS, Guilliams K, Gaies M, Gorga SM, Hall M, Hanson SJ, Hartman M, Hassinger AB, Irving SY, Jeffries H, Jouvet P, Kannan S, Karam O, Khemani RG, Kissoon N, Lacroix J, Laussen P, Leclerc F, Lee JH, Leteurtre S, Lobner K, McKiernan PJ, Menon K, Monagle P, Muszynski JA, Odetola F, Parker R, Pathan N, Pierce RW, Pineda J, Prince JM, Robinson KA, Rowan CM, Ryerson LM, Sanchez-Pinto LN, Schlapbach LJ, Selewski DT, Shekerdemian LS, Simon D, Smith LS, Squires JE, Squires RH, Sutherland SM, Ouellette Y, Spaeder MC, Srinivasan V, Steiner ME, Tasker RC, Thiagarajan R, Thomas N, Tissieres P, Traube C, Tucci M, Typpo KV, Wainwright MS, Ward SL, Watson RS, Weiss S, Whitney J, Willson D, Wynn JL, Yeyha N, Zimmerman JJ. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics. 2022 Jan 1; 149: S1-S12.
Muszynski JA, Banks R, Reeder RW, Hall MW, Berg RA, Zuppa A, Shanley TP, Cornell TT, Newth CJL, Pollack MM, Wessel D, Doctor A, Lin JC, Harrison RE, Meert KL, Dean JM, Holubkov R, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Outcomes Associated With Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study. Shock. 2022 Jan 1; 57: 88-94.
Mertz C, Glowinski R, Cohen SH, Mertz S, Ye F, Hall MW, Peeples ME, King T, Wang H, Leber AL, Sanchez PJ, Ramilo O, Mejias A. Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019. J Infect Dis. 2022 Jan 18; 225: 208-213.
Mukherjee R, Tompkins CA, Ostberg NP, Joshi AU, Massis LM, Vijayan V, Gera K, Monack D, Cornell TT, Hall MW, Mochly-Rosen D, Haileselassie B. Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance. Crit Care Med. 2022 Jan 24;
Penatzer JA, Alexander R, Simon S, Wolfe A, Breuer J, Hensley J, Fabia R, Hall M, Thakkar RK. Early detection of soluble CD27, BTLA, and TIM-3 predicts the development of nosocomial infection in pediatric burn patients. Front Immunol. 2022; 13: 940835.
Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2021 Dec 21;
Sribnick EA, Warner T, Hall MW. Traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma leads to immunosuppression and splenic alterations. J Neuroimmunol. 2021 Dec 15; 361: 577723.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Notterman DA, Colville G, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Post-Traumatic Growth in Parents following Their Child's Death in a Pediatric Intensive Care Unit. J Palliat Med. 2021 Oct 5;
Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, Overcoming COVID-19 Investigators.. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40: 101112.
Bline KE, Hall MW. Immune Function in Critically Ill Septic Children. Pathogens. 2021 Sep 25; 10:
Diaz-Diaz A, Bunsow E, Garcia-Maurino C, Moore-Clingenpeel M, Naples J, Juergensen A, Mertz S, Wang H, Leber AL, Gern J, Hall MW, Cohen DM, Ramilo O, Mejias A. Nasopharyngeal Codetection of H. influenzae and S. pneumoniae and Respiratory Syncytial Virus Disease Outcomes in Children. J Infect Dis. 2021 Sep 20;
Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators., Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates AR. Factors Associated With Functional Impairment After Pediatric Injury. JAMA Surg. 2021 Aug 1; 156: e212058.
Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS Jr, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 Jul 1; 385: 23-34.
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Complicated Grief, Depression and Post-Traumatic Stress Symptoms Among Bereaved Parents following their Child's Death in the Pediatric Intensive Care Unit: A Follow-Up Study. Am J Hosp Palliat Care. 2021 May 5; 10499091211015913.
Snyder A, Jedreski K, Fitch J, Wijeratne S, Wetzel A, Hensley J, Flowers M, Bline K, Hall MW, Muszynski JA. Transcriptomic Profiles in Children With Septic Shock With or Without Immunoparalysis. Front Immunol. 2021; 12: 733834.
Pinto NP, Berg RA, Zuppa AF, Newth CJ, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Nadkarni VM, Reeder RW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Front Pediatr. 2021; 9: 675374.
Srouji LS, Moore-Clingenpeel M, Hensley J, Steele L, Greathouse K, Anglim L, Hanson-Huber L, Nateri J, Nicol K, Hall MW, Ramilo O, Muszynski JA. Shock Severity Modifies Associations Between RBC Transfusion in the First 48 Hours of Sepsis Onset and the Duration of Organ Dysfunction in Critically Ill Septic Children. Pediatr Crit Care Med. 2020 Aug; 21: e475-e484.
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 Aug; 48: 1120-1128.
Hall MW, Joshi I, Leal L, Ooi EE. Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention. Clin Infect Dis. 2020 Jul 1;
Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 May 11;
Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, Heidemann SM, Kleinman LC, Sen AI, Hall MW, Priestley MA, McGuire JK, Boukas K, Sharron MP, Burns JP, International COVID-19 PICU Collaborative.. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. 2020 May 11;
Sribnick EA, Hensley J, Moore-Clingenpeel M, Muszynski JA, Thakkar RK, Hall MW. Nosocomial Infection Following Severe Traumatic Injury in Children. Pediatr Crit Care Med. 2020 May; 21: 443-450.
Gertz SJ, McArthur J, Hsing DD, Nitu ME, Smith LS, Loomis A, Fitzgerald JC, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Cheifetz IM, Rowan CM, Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network.. Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant. Transpl Infect Dis. 2020 Apr 19; e13297.
Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Apr 21;
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 329-337.
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 319-328.
Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators.. RIG-I and TLR4 Responses and Adverse Outcomes in Pediatric Influenza-Related Critical Illness. J Allergy Clin Immunol. 2020 Feb 5;
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: e52-e106.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: 186-195.
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 Feb; 46: 10-67.
Sribnick EA, Weber MD, Hall MW. Innate immune suppression after traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma. J Neuroimmunol. 2019 Dec 15; 337: 577073.
Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure. Pediatr Crit Care Med. 2019 Sep 18;
La Count S, Lovett ME, Zhao S, Kline D, O'Brien NF, Hall MW, Sribnick EA. Factors Associated With Poor Outcome in Pediatric Near-Hanging Injuries. J Emerg Med. 2019 Jul; 57: 21-28.
Hungerford JL, O'Brien N, Moore-Clingenpeel M, Sribnick EA, Sargel C, Hall M, Leonard JR, Tobias JD. Remifentanil for Sedation of Children With Traumatic Brain Injury. J Intensive Care Med. 2019 Jul; 34: 557-562.
Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Zuppa AF, Graham K, Twelves C, Diliberto MA, Landis WP, Tomanio E, Kwok J, Bell MJ, Abraham A, Sapru A, Alkhouli MF, Heidemann S, Pawluszka A, Hall MW, Steele L, Shanley TP, Weber M, Dalton HJ, Bell A, Mourani PM, Malone K, Locandro C, Coleman W, Peterson A, Thelen J, Doctor A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators.. The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation. 2019 Jun 6; 141: 88-95.
Thakkar RK, Weiss SL, Fitzgerald JC, Keele L, Thomas NJ, Nadkarni VM, Muszynski JA, Hall MW, SPROUT Investigators., Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis. J Surg Res. 2019 May 7; 242: 100-110.
Hall MW. Immune Modulation in Pediatric Sepsis. J Pediatr Intensive Care. 2019 Mar; 8: 42-50.
Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, Han Y, Easley KA, Knezevic A, Dai T, Paden M, Carcillo JA, Thrombocytopenia-Associated Multiple Organ Failure (TAMOF) Network Study Group.. Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience. Crit Care Med. 2019 Mar; 47: e173-e181.
Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, PALISI PICFLU Investigators., Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10: 1005.
Karsies T, Moore-Clingenpeel M, Hall M. Development and Validation of a Model to Predict Growth of Potentially Antibiotic-Resistant Gram-Negative Bacilli in Critically Ill Children With Suspected Infection. Open Forum Infect Dis. 2018 Nov; 5: ofy278.
Rowan CM, McArthur J, Hsing DD, Gertz SJ, Smith LS, Loomis A, Fitzgerald JC, Nitu ME, Moser EAS, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. Acute Respiratory Failure in Pediatric Hematopoietic Cell Transplantation: A Multicenter Study. Crit Care Med. 2018 Oct; 46: e967-e974.
Stenson EK, Cvijanovich NZ, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Jain PN, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Wong HR, Anas N. Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock. Intensive Care Med. 2018 Oct 15;
Willson DF, Hall M, Beardsley A, Hoot M, Kirby A, Hays S, Erickson S, Truemper E, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Pediatric Ventilator-Associated Events: Analysis of the Pediatric Ventilator-Associated Infection Data. Pediatr Crit Care Med. 2018 Sep 18;
Muszynski JA, Nofziger R, Moore-Clingenpeel M, Greathouse K, Anglim L, Steele L, Hensley J, Hanson-Huber L, Nateri J, Ramilo O, Hall MW. Early Immune Function and Duration of Organ Dysfunction in Critically III Children with Sepsis. Am J Respir Crit Care Med. 2018 Aug 1; 198: 361-369.
Thakkar RK, Diltz Z, Drews JD, Wheeler KK, Shi J, Devine R, Fabia R, Hall M. Abnormal lymphocyte response after pediatric thermal injury is associated with adverse outcomes. J Surg Res. 2018 Aug; 228: 221-227.
Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt K, Pediatric Intensive Care Influenza (PICFLU) Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network.. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children with Influenza-Related Critical Illness. Clin Infect Dis. 2018 Jun 9;
Rowan CM, Loomis A, McArthur J, Smith LS, Gertz SJ, Fitzgerald JC, Nitu ME, Moser EA, Hsing DD, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient. Respir Care. 2018 Apr; 63: 404-411.
Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR. Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. Pediatr Crit Care Med. 2018 Feb; 19: 155-160.
Devine RA, Diltz Z, Hall MW, Thakkar RK. The systemic immune response to pediatric thermal injury. Int J Burns Trauma. 2018; 8: 6-16.
Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK. The Functional Immune Response of Patients on Extracorporeal Life Support. ASAIO J. 2018 Jan 10;
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Lab(s)
Center for Clinical and Translational Research
The Immune Surveillance Laboratory at The Research institute at Nationwide Children’s Hospital is a high-throughput clinical and translational research laboratory dedicated to understanding the immune response to critical illness. The laboratory provides immune function testing services for single- and multi-center studies of immune function in critically ill children across North America.
Lab(s)
Center for Clinical and Translational Research
Center for Clinical and Translational Research
Berg RA, Morgan RW, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM. Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study. Crit Care Med. 2023 Jan 1; 51: 91-102. Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Michael Dean J, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, KirkpatrickN T, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, NaimCE MY, Notterman D, Page K, Pollack MM, Qunibi D, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Calcium Use during Paediatric In-hospital Cardiac Arrest is Associated with Worse Outcomes. Resuscitation. 2022 Dec 21; 109673. Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC Jr, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators. Association of Asthma with Treatments and Outcomes in Children with Critical Influenza. J Allergy Clin Immunol Pract. 2022 Nov 12; LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS Jr, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2022 Nov 7; Ross CE, Burns JP, Grossestreuer AV, Bhattarai P, McKiernan CA, Franks JD, Lehmann S, Sorcher JL, Sharron MP, Wai K, Al-Wahab H, Boukas K, Hall MW, Ru G, Sen AI, Rajasekhar HR, Kleinman LC, McGuire JK, Arrington AS, Munoz-Rivas F, Osborne CM, Shekerdemian LS. Trends in Disease Severity Among Critically Ill Children With Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Multicenter Cohort Study in the United States. Pediatr Crit Care Med. 2022 Nov 17; Horvat CM, Fabio A, Nagin DS, Banks RK, Qin Y, Park HJ, Kernan KF, Canna SW, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Sward K, Holubkov R, Notterman DA, Dean JM, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels. Pediatr Crit Care Med. 2022 Sep 30; Zambrano LD, Ly KN, Link-Gelles R, Newhams MM, Akande M, Wu MJ, Feldstein LR, Tarquinio KM, Sahni LC, Riggs BJ, Singh AR, Fitzgerald JC, Schuster JE, Giuliano JS Jr, Englund JA, Hume JR, Hall MW, Osborne CM, Doymaz S, Rowan CM, Babbitt CJ, Clouser KN, Horwitz SM, Chou J, Patel MM, Hobbs C, Randolph AG, Campbell AP, Overcoming COVID-19 Investigators.. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. Pediatr Infect Dis J. 2022 Sep 7; Bline KE, Muszynski JA, Guess AJ, Menocha S, Moore-Clingenpeel MD, Popelka JK, Hensley JM, Steele LM, Goldthwaite IC, Jedreski KJ, Hall MW. Novel Identification of Myeloid-Derived Suppressor Cells in Children With Septic Shock. Pediatr Crit Care Med. 2022 Sep 8; Morgan RW, Wolfe HA, Reeder RW, Alvey JS, Frazier AH, Friess SH, Maa T, McQuillen PS, Meert KL, Nadkarni VM, Sharron MP, Siems A, Yates AR, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Hall M, Hehir D, Horvat CM, Huard LL, Manga A, Mourani PM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa AF, Berg RA, Sutton RM. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022 Sep 2; Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFlu) Investigators and the TOPMed Investigators.. DDX58 is Associated with Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 Aug 20; Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host respiratory transcriptome signature associated with poor outcome in children with influenza-Staphylococcus aureus pneumonia. J Infect Dis. 2022 Jul 28; Cashen K, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators.. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 Jul 26; Morin L, Hall M, de Souza D, Guoping L, Jabornisky R, Shime N, Ranjit S, Gilholm P, Nakagawa S, Zimmerman JJ, Sorce LR, Argent A, Kissoon N, Tissières P, Watson RS, Schlapbach LJ, Pediatric Sepsis Definition Taskforce.. The Current and Future State of Pediatric Sepsis Definitions: An International Survey. Pediatrics. 2022 Jun 1; 149: Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Soma VL, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG, Pediatric Intensive Care Influenza., Overcoming COVID-19 Investigators.. Life-Threatening Complications of Influenza versus COVID-19 in U.S. Children. Clin Infect Dis. 2022 Jun 19; Salud D, Reeder RW, Banks RK, Meert KL, Berg RA, Zuppa A, Newth CJ, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Varni JW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med. 2022 Jun 10; Qin Y, Kernan KF, Fan Z, Park HJ, Kim S, Canna SW, Kellum JA, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Michael Dean J, Carcillo JA. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 May 7; 26: 128. Ames SG, Banks RK, Zinter MS, Fink EL, McQuillen PS, Hall MW, Zuppa A, Meert KL, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Berg RA, Mareboina M, Holubkov R, Dean JM, Notterman DA, Sapru A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2022 Apr 22; Thakkar RK, Penatzer J, Simon S, Steele L, Fabia R, Groner JI, Keesari R, Hall M. Measures of Adaptive Immune Function Predict the Risk of Nosocomial Infection in Pediatric Burn Patients. J Burn Care Res. 2022 Apr 18; Tsitsiklis A, Osborne CM, Kamm J, Williamson K, Kalantar K, Dudas G, Caldera S, Lyden A, Tan M, Neff N, Soesanto V, Harris JK, Ambroggio L, Maddux AB, Carpenter TC, Reeder RW, Locandro C, Simões EAF, Leroue MK, Hall MW, Zuppa AF, Carcillo J, Meert KL, Sapru A, Pollack MM, McQuillen PS, Notterman DA, Dean JM, Zinter MS, Wagner BD, DeRisi JL, Mourani PM, Langelier CR. Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics. Lancet Microbe. 2022 Apr; 3: e284-e293. ICU-RESUS and Eunice Kennedy Shriver National Institute of Child Health., Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups., Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bishop R, Bochkoris M, Burns C, Diddle JW, Federman M, Fernandez R, Franzon D, Frazier AH, Friess SH, Graham K, Hehir D, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Schneiter C, Sharron MP, Siems A, Srivastava N, Tabbutt S, Tilford B, Viteri S, Berg RA, Bell MJ, Carcillo JA, Carpenter TC, Dean JM, Fink EL, Hall M, McQuillen PS, Meert KL, Mourani PM, Notterman D, Pollack MM, Sapru A, Wessel D, Yates AR, Zuppa AF. Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial. JAMA. 2022 Mar 8; 327: 934-945. Yates AR, Berger JT, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Notterman DA, Holubkov R, Dean JM, Wessel DL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients. Pediatr Crit Care Med. 2022 Feb 23; Farhat MH, Shadley JD, Halligan NLN, Hall MW, Popova AP, Quasney MW, Dahmer MK. Differences in the Genomic Profiles of Immunoparalyzed and Nonimmunoparalyzed Children With Sepsis: A Pilot Study. Pediatr Crit Care Med. 2022 Feb 1; 23: 79-88. Sribnick EA, Popovich PG, Hall MW. Central nervous system injury-induced immune suppression. Neurosurg Focus. 2022 Feb; 52: E10. Olson SM, Newhams MM, Halasa NB, Feldstein LR, Novak T, Weiss SL, Coates BM, Schuster JE, Schwarz AJ, Maddux AB, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Stewart LS, Barnes JR, Patel MM, Randolph AG, Pediatric Intensive Care Influenza Investigators .. Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. Clin Infect Dis. 2022 Jan 13; Schuster JE, Halasa NB, Nakamura M, Levy ER, Fitzgerald JC, Young CC, Newhams MM, Bourgeois F, Staat MA, Hobbs CV, Dapul H, Feldstein LR, Jackson AM, Mack EH, Walker TC, Maddux AB, Spinella PC, Loftis LL, Kong M, Rowan CM, Bembea MM, McLaughlin GE, Hall MW, Babbitt CJ, Maamari M, Zinter MS, Cvijanovich NZ, Michelson KN, Gertz SJ, Carroll CL, Thomas NJ, Giuliano JS, Singh AR, Hymes SR, Schwarz AJ, McGuire JK, Nofziger RA, Flori HR, Clouser KN, Wellnitz K, Cullimore ML, Hume JR, Patel M, Randolph AG, Overcoming COVID-19 Investigators.. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 Jan 12; Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo JA. Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis. J Clin Immunol. 2022 Jan 1; Hall MW, Carcillo JA, Cornell T, Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative.. Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022 Jan 1; 149: S91-S98. Bembea MM, Agus M, Akcan-Arikan A, Alexander P, Basu R, Bennett TD, Bohn D, Brandão LR, Brown AM, Carcillo JA, Checchia P, Cholette J, Cheifetz IM, Cornell T, Doctor A, Eckerle M, Erickson S, Farris RWD, Faustino EVS, Fitzgerald JC, Fuhrman DY, Giuliano JS, Guilliams K, Gaies M, Gorga SM, Hall M, Hanson SJ, Hartman M, Hassinger AB, Irving SY, Jeffries H, Jouvet P, Kannan S, Karam O, Khemani RG, Kissoon N, Lacroix J, Laussen P, Leclerc F, Lee JH, Leteurtre S, Lobner K, McKiernan PJ, Menon K, Monagle P, Muszynski JA, Odetola F, Parker R, Pathan N, Pierce RW, Pineda J, Prince JM, Robinson KA, Rowan CM, Ryerson LM, Sanchez-Pinto LN, Schlapbach LJ, Selewski DT, Shekerdemian LS, Simon D, Smith LS, Squires JE, Squires RH, Sutherland SM, Ouellette Y, Spaeder MC, Srinivasan V, Steiner ME, Tasker RC, Thiagarajan R, Thomas N, Tissieres P, Traube C, Tucci M, Typpo KV, Wainwright MS, Ward SL, Watson RS, Weiss S, Whitney J, Willson D, Wynn JL, Yeyha N, Zimmerman JJ. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics. 2022 Jan 1; 149: S1-S12. Muszynski JA, Banks R, Reeder RW, Hall MW, Berg RA, Zuppa A, Shanley TP, Cornell TT, Newth CJL, Pollack MM, Wessel D, Doctor A, Lin JC, Harrison RE, Meert KL, Dean JM, Holubkov R, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Outcomes Associated With Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study. Shock. 2022 Jan 1; 57: 88-94. Mertz C, Glowinski R, Cohen SH, Mertz S, Ye F, Hall MW, Peeples ME, King T, Wang H, Leber AL, Sanchez PJ, Ramilo O, Mejias A. Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019. J Infect Dis. 2022 Jan 18; 225: 208-213. Mukherjee R, Tompkins CA, Ostberg NP, Joshi AU, Massis LM, Vijayan V, Gera K, Monack D, Cornell TT, Hall MW, Mochly-Rosen D, Haileselassie B. Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance. Crit Care Med. 2022 Jan 24; Penatzer JA, Alexander R, Simon S, Wolfe A, Breuer J, Hensley J, Fabia R, Hall M, Thakkar RK. Early detection of soluble CD27, BTLA, and TIM-3 predicts the development of nosocomial infection in pediatric burn patients. Front Immunol. 2022; 13: 940835. Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2021 Dec 21; Sribnick EA, Warner T, Hall MW. Traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma leads to immunosuppression and splenic alterations. J Neuroimmunol. 2021 Dec 15; 361: 577723. Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Notterman DA, Colville G, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Post-Traumatic Growth in Parents following Their Child's Death in a Pediatric Intensive Care Unit. J Palliat Med. 2021 Oct 5; Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, Overcoming COVID-19 Investigators.. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40: 101112. Bline KE, Hall MW. Immune Function in Critically Ill Septic Children. Pathogens. 2021 Sep 25; 10: Diaz-Diaz A, Bunsow E, Garcia-Maurino C, Moore-Clingenpeel M, Naples J, Juergensen A, Mertz S, Wang H, Leber AL, Gern J, Hall MW, Cohen DM, Ramilo O, Mejias A. Nasopharyngeal Codetection of H. influenzae and S. pneumoniae and Respiratory Syncytial Virus Disease Outcomes in Children. J Infect Dis. 2021 Sep 20; Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators., Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates AR. Factors Associated With Functional Impairment After Pediatric Injury. JAMA Surg. 2021 Aug 1; 156: e212058. Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS Jr, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 Jul 1; 385: 23-34. Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Complicated Grief, Depression and Post-Traumatic Stress Symptoms Among Bereaved Parents following their Child's Death in the Pediatric Intensive Care Unit: A Follow-Up Study. Am J Hosp Palliat Care. 2021 May 5; 10499091211015913. Snyder A, Jedreski K, Fitch J, Wijeratne S, Wetzel A, Hensley J, Flowers M, Bline K, Hall MW, Muszynski JA. Transcriptomic Profiles in Children With Septic Shock With or Without Immunoparalysis. Front Immunol. 2021; 12: 733834. Pinto NP, Berg RA, Zuppa AF, Newth CJ, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Nadkarni VM, Reeder RW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Front Pediatr. 2021; 9: 675374. Srouji LS, Moore-Clingenpeel M, Hensley J, Steele L, Greathouse K, Anglim L, Hanson-Huber L, Nateri J, Nicol K, Hall MW, Ramilo O, Muszynski JA. Shock Severity Modifies Associations Between RBC Transfusion in the First 48 Hours of Sepsis Onset and the Duration of Organ Dysfunction in Critically Ill Septic Children. Pediatr Crit Care Med. 2020 Aug; 21: e475-e484. Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 Aug; 48: 1120-1128. Hall MW, Joshi I, Leal L, Ooi EE. Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention. Clin Infect Dis. 2020 Jul 1; Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 May 11; Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, Heidemann SM, Kleinman LC, Sen AI, Hall MW, Priestley MA, McGuire JK, Boukas K, Sharron MP, Burns JP, International COVID-19 PICU Collaborative.. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. 2020 May 11; Sribnick EA, Hensley J, Moore-Clingenpeel M, Muszynski JA, Thakkar RK, Hall MW. Nosocomial Infection Following Severe Traumatic Injury in Children. Pediatr Crit Care Med. 2020 May; 21: 443-450. Gertz SJ, McArthur J, Hsing DD, Nitu ME, Smith LS, Loomis A, Fitzgerald JC, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Cheifetz IM, Rowan CM, Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network.. Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant. Transpl Infect Dis. 2020 Apr 19; e13297. Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Apr 21; Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 329-337. Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 319-328. Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators.. RIG-I and TLR4 Responses and Adverse Outcomes in Pediatric Influenza-Related Critical Illness. J Allergy Clin Immunol. 2020 Feb 5; Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: e52-e106. Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: 186-195. Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 Feb; 46: 10-67. Sribnick EA, Weber MD, Hall MW. Innate immune suppression after traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma. J Neuroimmunol. 2019 Dec 15; 337: 577073. Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure. Pediatr Crit Care Med. 2019 Sep 18; La Count S, Lovett ME, Zhao S, Kline D, O'Brien NF, Hall MW, Sribnick EA. Factors Associated With Poor Outcome in Pediatric Near-Hanging Injuries. J Emerg Med. 2019 Jul; 57: 21-28. Hungerford JL, O'Brien N, Moore-Clingenpeel M, Sribnick EA, Sargel C, Hall M, Leonard JR, Tobias JD. Remifentanil for Sedation of Children With Traumatic Brain Injury. J Intensive Care Med. 2019 Jul; 34: 557-562. Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Zuppa AF, Graham K, Twelves C, Diliberto MA, Landis WP, Tomanio E, Kwok J, Bell MJ, Abraham A, Sapru A, Alkhouli MF, Heidemann S, Pawluszka A, Hall MW, Steele L, Shanley TP, Weber M, Dalton HJ, Bell A, Mourani PM, Malone K, Locandro C, Coleman W, Peterson A, Thelen J, Doctor A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators.. The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation. 2019 Jun 6; 141: 88-95. Thakkar RK, Weiss SL, Fitzgerald JC, Keele L, Thomas NJ, Nadkarni VM, Muszynski JA, Hall MW, SPROUT Investigators., Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis. J Surg Res. 2019 May 7; 242: 100-110. Hall MW. Immune Modulation in Pediatric Sepsis. J Pediatr Intensive Care. 2019 Mar; 8: 42-50. Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, Han Y, Easley KA, Knezevic A, Dai T, Paden M, Carcillo JA, Thrombocytopenia-Associated Multiple Organ Failure (TAMOF) Network Study Group.. Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience. Crit Care Med. 2019 Mar; 47: e173-e181. Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, PALISI PICFLU Investigators., Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10: 1005. Karsies T, Moore-Clingenpeel M, Hall M. Development and Validation of a Model to Predict Growth of Potentially Antibiotic-Resistant Gram-Negative Bacilli in Critically Ill Children With Suspected Infection. Open Forum Infect Dis. 2018 Nov; 5: ofy278. Rowan CM, McArthur J, Hsing DD, Gertz SJ, Smith LS, Loomis A, Fitzgerald JC, Nitu ME, Moser EAS, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. Acute Respiratory Failure in Pediatric Hematopoietic Cell Transplantation: A Multicenter Study. Crit Care Med. 2018 Oct; 46: e967-e974. Stenson EK, Cvijanovich NZ, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Jain PN, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Wong HR, Anas N. Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock. Intensive Care Med. 2018 Oct 15; Willson DF, Hall M, Beardsley A, Hoot M, Kirby A, Hays S, Erickson S, Truemper E, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Pediatric Ventilator-Associated Events: Analysis of the Pediatric Ventilator-Associated Infection Data. Pediatr Crit Care Med. 2018 Sep 18; Muszynski JA, Nofziger R, Moore-Clingenpeel M, Greathouse K, Anglim L, Steele L, Hensley J, Hanson-Huber L, Nateri J, Ramilo O, Hall MW. Early Immune Function and Duration of Organ Dysfunction in Critically III Children with Sepsis. Am J Respir Crit Care Med. 2018 Aug 1; 198: 361-369. Thakkar RK, Diltz Z, Drews JD, Wheeler KK, Shi J, Devine R, Fabia R, Hall M. Abnormal lymphocyte response after pediatric thermal injury is associated with adverse outcomes. J Surg Res. 2018 Aug; 228: 221-227. Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt K, Pediatric Intensive Care Influenza (PICFLU) Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network.. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children with Influenza-Related Critical Illness. Clin Infect Dis. 2018 Jun 9; Rowan CM, Loomis A, McArthur J, Smith LS, Gertz SJ, Fitzgerald JC, Nitu ME, Moser EA, Hsing DD, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient. Respir Care. 2018 Apr; 63: 404-411. Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR. Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. Pediatr Crit Care Med. 2018 Feb; 19: 155-160. Devine RA, Diltz Z, Hall MW, Thakkar RK. The systemic immune response to pediatric thermal injury. Int J Burns Trauma. 2018; 8: 6-16. Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK. The Functional Immune Response of Patients on Extracorporeal Life Support. ASAIO J. 2018 Jan 10;
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- Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo JA. Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis. J Clin Immunol. 2022 Jan 1;
- Hall MW, Carcillo JA, Cornell T, Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative.. Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022 Jan 1; 149: S91-S98.
- Bembea MM, Agus M, Akcan-Arikan A, Alexander P, Basu R, Bennett TD, Bohn D, Brandão LR, Brown AM, Carcillo JA, Checchia P, Cholette J, Cheifetz IM, Cornell T, Doctor A, Eckerle M, Erickson S, Farris RWD, Faustino EVS, Fitzgerald JC, Fuhrman DY, Giuliano JS, Guilliams K, Gaies M, Gorga SM, Hall M, Hanson SJ, Hartman M, Hassinger AB, Irving SY, Jeffries H, Jouvet P, Kannan S, Karam O, Khemani RG, Kissoon N, Lacroix J, Laussen P, Leclerc F, Lee JH, Leteurtre S, Lobner K, McKiernan PJ, Menon K, Monagle P, Muszynski JA, Odetola F, Parker R, Pathan N, Pierce RW, Pineda J, Prince JM, Robinson KA, Rowan CM, Ryerson LM, Sanchez-Pinto LN, Schlapbach LJ, Selewski DT, Shekerdemian LS, Simon D, Smith LS, Squires JE, Squires RH, Sutherland SM, Ouellette Y, Spaeder MC, Srinivasan V, Steiner ME, Tasker RC, Thiagarajan R, Thomas N, Tissieres P, Traube C, Tucci M, Typpo KV, Wainwright MS, Ward SL, Watson RS, Weiss S, Whitney J, Willson D, Wynn JL, Yeyha N, Zimmerman JJ. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics. 2022 Jan 1; 149: S1-S12.
- Muszynski JA, Banks R, Reeder RW, Hall MW, Berg RA, Zuppa A, Shanley TP, Cornell TT, Newth CJL, Pollack MM, Wessel D, Doctor A, Lin JC, Harrison RE, Meert KL, Dean JM, Holubkov R, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Outcomes Associated With Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study. Shock. 2022 Jan 1; 57: 88-94.
- Mertz C, Glowinski R, Cohen SH, Mertz S, Ye F, Hall MW, Peeples ME, King T, Wang H, Leber AL, Sanchez PJ, Ramilo O, Mejias A. Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019. J Infect Dis. 2022 Jan 18; 225: 208-213.
- Mukherjee R, Tompkins CA, Ostberg NP, Joshi AU, Massis LM, Vijayan V, Gera K, Monack D, Cornell TT, Hall MW, Mochly-Rosen D, Haileselassie B. Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance. Crit Care Med. 2022 Jan 24;
- Penatzer JA, Alexander R, Simon S, Wolfe A, Breuer J, Hensley J, Fabia R, Hall M, Thakkar RK. Early detection of soluble CD27, BTLA, and TIM-3 predicts the development of nosocomial infection in pediatric burn patients. Front Immunol. 2022; 13: 940835.
- Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2021 Dec 21;
- Sribnick EA, Warner T, Hall MW. Traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma leads to immunosuppression and splenic alterations. J Neuroimmunol. 2021 Dec 15; 361: 577723.
- Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Notterman DA, Colville G, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Post-Traumatic Growth in Parents following Their Child’s Death in a Pediatric Intensive Care Unit. J Palliat Med. 2021 Oct 5;
- Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, Overcoming COVID-19 Investigators.. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40: 101112.
- Bline KE, Hall MW. Immune Function in Critically Ill Septic Children. Pathogens. 2021 Sep 25; 10:
- Diaz-Diaz A, Bunsow E, Garcia-Maurino C, Moore-Clingenpeel M, Naples J, Juergensen A, Mertz S, Wang H, Leber AL, Gern J, Hall MW, Cohen DM, Ramilo O, Mejias A. Nasopharyngeal Codetection of H. influenzae and S. pneumoniae and Respiratory Syncytial Virus Disease Outcomes in Children. J Infect Dis. 2021 Sep 20;
- Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators., Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates AR. Factors Associated With Functional Impairment After Pediatric Injury. JAMA Surg. 2021 Aug 1; 156: e212058.
- Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS Jr, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG, Overcoming COVID-19 Investigators.. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 Jul 1; 385: 23-34.
- Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).. Complicated Grief, Depression and Post-Traumatic Stress Symptoms Among Bereaved Parents following their Child’s Death in the Pediatric Intensive Care Unit: A Follow-Up Study. Am J Hosp Palliat Care. 2021 May 5; 10499091211015913.
- Snyder A, Jedreski K, Fitch J, Wijeratne S, Wetzel A, Hensley J, Flowers M, Bline K, Hall MW, Muszynski JA. Transcriptomic Profiles in Children With Septic Shock With or Without Immunoparalysis. Front Immunol. 2021; 12: 733834.
- Pinto NP, Berg RA, Zuppa AF, Newth CJ, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Nadkarni VM, Reeder RW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Front Pediatr. 2021; 9: 675374.
- Srouji LS, Moore-Clingenpeel M, Hensley J, Steele L, Greathouse K, Anglim L, Hanson-Huber L, Nateri J, Nicol K, Hall MW, Ramilo O, Muszynski JA. Shock Severity Modifies Associations Between RBC Transfusion in the First 48 Hours of Sepsis Onset and the Duration of Organ Dysfunction in Critically Ill Septic Children. Pediatr Crit Care Med. 2020 Aug; 21: e475-e484.
- Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 Aug; 48: 1120-1128.
- Hall MW, Joshi I, Leal L, Ooi EE. Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention. Clin Infect Dis. 2020 Jul 1;
- Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 May 11;
- Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, Heidemann SM, Kleinman LC, Sen AI, Hall MW, Priestley MA, McGuire JK, Boukas K, Sharron MP, Burns JP, International COVID-19 PICU Collaborative.. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. 2020 May 11;
- Sribnick EA, Hensley J, Moore-Clingenpeel M, Muszynski JA, Thakkar RK, Hall MW. Nosocomial Infection Following Severe Traumatic Injury in Children. Pediatr Crit Care Med. 2020 May; 21: 443-450.
- Gertz SJ, McArthur J, Hsing DD, Nitu ME, Smith LS, Loomis A, Fitzgerald JC, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Cheifetz IM, Rowan CM, Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network.. Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant. Transpl Infect Dis. 2020 Apr 19; e13297.
- Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Apr 21;
- Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 329-337.
- Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.. Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar; 48: 319-328.
- Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators.. RIG-I and TLR4 Responses and Adverse Outcomes in Pediatric Influenza-Related Critical Illness. J Allergy Clin Immunol. 2020 Feb 5;
- Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: e52-e106.
- Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb; 21: 186-195.
- Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 Feb; 46: 10-67.
- Sribnick EA, Weber MD, Hall MW. Innate immune suppression after traumatic brain injury and hemorrhage in a juvenile rat model of polytrauma. J Neuroimmunol. 2019 Dec 15; 337: 577073.
- Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.. A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure. Pediatr Crit Care Med. 2019 Sep 18;
- La Count S, Lovett ME, Zhao S, Kline D, O’Brien NF, Hall MW, Sribnick EA. Factors Associated With Poor Outcome in Pediatric Near-Hanging Injuries. J Emerg Med. 2019 Jul; 57: 21-28.
- Hungerford JL, O’Brien N, Moore-Clingenpeel M, Sribnick EA, Sargel C, Hall M, Leonard JR, Tobias JD. Remifentanil for Sedation of Children With Traumatic Brain Injury. J Intensive Care Med. 2019 Jul; 34: 557-562.
- Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Zuppa AF, Graham K, Twelves C, Diliberto MA, Landis WP, Tomanio E, Kwok J, Bell MJ, Abraham A, Sapru A, Alkhouli MF, Heidemann S, Pawluszka A, Hall MW, Steele L, Shanley TP, Weber M, Dalton HJ, Bell A, Mourani PM, Malone K, Locandro C, Coleman W, Peterson A, Thelen J, Doctor A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators.. The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation. 2019 Jun 6; 141: 88-95.
- Thakkar RK, Weiss SL, Fitzgerald JC, Keele L, Thomas NJ, Nadkarni VM, Muszynski JA, Hall MW, SPROUT Investigators., Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis. J Surg Res. 2019 May 7; 242: 100-110.
- Hall MW. Immune Modulation in Pediatric Sepsis. J Pediatr Intensive Care. 2019 Mar; 8: 42-50.
- Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, Han Y, Easley KA, Knezevic A, Dai T, Paden M, Carcillo JA, Thrombocytopenia-Associated Multiple Organ Failure (TAMOF) Network Study Group.. Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience. Crit Care Med. 2019 Mar; 47: e173-e181.
- Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, PALISI PICFLU Investigators., Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10: 1005.
- Karsies T, Moore-Clingenpeel M, Hall M. Development and Validation of a Model to Predict Growth of Potentially Antibiotic-Resistant Gram-Negative Bacilli in Critically Ill Children With Suspected Infection. Open Forum Infect Dis. 2018 Nov; 5: ofy278.
- Rowan CM, McArthur J, Hsing DD, Gertz SJ, Smith LS, Loomis A, Fitzgerald JC, Nitu ME, Moser EAS, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. Acute Respiratory Failure in Pediatric Hematopoietic Cell Transplantation: A Multicenter Study. Crit Care Med. 2018 Oct; 46: e967-e974.
- Stenson EK, Cvijanovich NZ, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Jain PN, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Wong HR, Anas N. Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock. Intensive Care Med. 2018 Oct 15;
- Willson DF, Hall M, Beardsley A, Hoot M, Kirby A, Hays S, Erickson S, Truemper E, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.. Pediatric Ventilator-Associated Events: Analysis of the Pediatric Ventilator-Associated Infection Data. Pediatr Crit Care Med. 2018 Sep 18;
- Muszynski JA, Nofziger R, Moore-Clingenpeel M, Greathouse K, Anglim L, Steele L, Hensley J, Hanson-Huber L, Nateri J, Ramilo O, Hall MW. Early Immune Function and Duration of Organ Dysfunction in Critically III Children with Sepsis. Am J Respir Crit Care Med. 2018 Aug 1; 198: 361-369.
- Thakkar RK, Diltz Z, Drews JD, Wheeler KK, Shi J, Devine R, Fabia R, Hall M. Abnormal lymphocyte response after pediatric thermal injury is associated with adverse outcomes. J Surg Res. 2018 Aug; 228: 221-227.
- Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt K, Pediatric Intensive Care Influenza (PICFLU) Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network.. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children with Influenza-Related Critical Illness. Clin Infect Dis. 2018 Jun 9;
- Rowan CM, Loomis A, McArthur J, Smith LS, Gertz SJ, Fitzgerald JC, Nitu ME, Moser EA, Hsing DD, Duncan CN, Mahadeo KM, Moffet J, Hall MW, Pinos EL, Tamburro RF, Cheifetz IM, Investigators of the Pediatric Acute Lung Injury and Sepsis Network.. High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient. Respir Care. 2018 Apr; 63: 404-411.
- Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR. Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. Pediatr Crit Care Med. 2018 Feb; 19: 155-160.
- Devine RA, Diltz Z, Hall MW, Thakkar RK. The systemic immune response to pediatric thermal injury. Int J Burns Trauma. 2018; 8: 6-16.
- Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK. The Functional Immune Response of Patients on Extracorporeal Life Support. ASAIO J. 2018 Jan 10;
Education
Date of Appointment at Nationwide Children’s Hospital: 09/27/2002
Board Certifications
Pediatric Critical Care Pediatrics
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2002
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2001
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/23/1998
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1997
Internship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1995
Medical School
University of Virginia
Date Completed: 05/22/1994
Education
Date of Appointment at Nationwide Children’s Hospital: 09/27/2002
Board Certifications
Pediatric Critical Care Pediatrics
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2002
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2001
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/23/1998
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1997
Internship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1995
Medical School
University of Virginia
Date Completed: 05/22/1994
Education
Date of Appointment at Nationwide Children’s Hospital: 09/27/2002
Board Certifications
Pediatric Critical Care Pediatrics
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2002
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2001
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/23/1998
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1997
Internship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1995
Medical School
University of Virginia
Date Completed: 05/22/1994
Date of Appointment at Nationwide Children’s Hospital: 09/27/2002
Board Certifications
Pediatric Critical Care Pediatrics
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2002
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2001
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/23/1998
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1997
Internship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1995
Medical School
University of Virginia
Date Completed: 05/22/1994
Date of Appointment at Nationwide Children’s Hospital: 09/27/2002
Board Certifications
Pediatric Critical Care Pediatrics
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2002
Fellowship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/2001
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/23/1998
Residency
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1997
Internship
Children’s Hospital of Pittsburgh of UPMC
Date Completed: 06/30/1995
Medical School
University of Virginia
Date Completed: 05/22/1994
- Pediatric Critical Care
- Pediatrics
Professional Experience
2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2012 - 2020 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Associate Professor of Pediatrics2002 - 2012 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Assistant Professor of Pediatrics2001 - 2002 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Research Fellow/Instructor1998 - 2001 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Fellow1997 - 1998 Pediatrics,Children’s Hospital of Pittsburgh, Chief Resident/Instructor1994 - 1997 Pediatrics, Children’s Hospital of Pittsburgh, Resident
Professional Experience
2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2012 - 2020 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Associate Professor of Pediatrics2002 - 2012 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Assistant Professor of Pediatrics2001 - 2002 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Research Fellow/Instructor1998 - 2001 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Fellow1997 - 1998 Pediatrics,Children’s Hospital of Pittsburgh, Chief Resident/Instructor1994 - 1997 Pediatrics, Children’s Hospital of Pittsburgh, Resident
Professional Experience
2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2012 - 2020 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Associate Professor of Pediatrics2002 - 2012 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Assistant Professor of Pediatrics2001 - 2002 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Research Fellow/Instructor1998 - 2001 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Fellow1997 - 1998 Pediatrics,Children’s Hospital of Pittsburgh, Chief Resident/Instructor1994 - 1997 Pediatrics, Children’s Hospital of Pittsburgh, Resident
2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics2012 - 2020 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Associate Professor of Pediatrics2002 - 2012 The Ohio State University College of Medicine, Nationwide Children’s Hospital, Assistant Professor of Pediatrics2001 - 2002 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Research Fellow/Instructor1998 - 2001 Pediatric Critical Care Med, Children’s Hospital of Pittsburgh, Fellow1997 - 1998 Pediatrics,Children’s Hospital of Pittsburgh, Chief Resident/Instructor1994 - 1997 Pediatrics, Children’s Hospital of Pittsburgh, Resident
2020 - Present The Ohio State University College of Medicine, Nationwide Children’s Hospital, Professor of Pediatrics
Contact Information
Pediatrics
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
Critical Care700 Children's DrColumbus, OH 43205 (map)
Contact Information
Pediatrics
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
Critical Care700 Children's DrColumbus, OH 43205 (map)
Contact Information
Pediatrics
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
Critical Care700 Children's DrColumbus, OH 43205 (map)
Pediatrics
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
Critical Care700 Children's DrColumbus, OH 43205 (map)
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
Critical Care700 Children's DrColumbus, OH 43205 (map)
Call us at: (614) 722-3435
Fax us at: (614) 722-3443
Critical Care700 Children's DrColumbus, OH 43205 (map)
- Call us at:
- (614) 722-3435
- Fax us at:
- (614) 722-3443
- Critical Care700 Children’s DrColumbus, OH 43205 (map)
