Contact Information

Call us at: (614) 355-3675

Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)

Learn more about Mariam Mathew

Biography

Mariam Mathew, PhD, FACMG is a clinical director within the Institute for Genomic Medicine. She received her PhD at the University of Toronto, Canada where she focused on variant fusions in acute promyelocytic leukemia. Her interest in clinical diagnostics expanded through the course of her post-doctoral work at the University Health Network - Advanced Molecular Diagnostics Laboratory in Toronto, where she led the analytical validation and implementation process for a targeted Next Generation Sequencing panel for hematological malignancies, and contributed to designing a variant classification system directed at interpreting somatic variant profiles. In 2019, Dr. Mathew completed an ABMGG Laboratory Genetics and Genomics fellowship at the University of Chicago. Her interests focus on the application of cytogenetic and molecular techniques to understand the genetic basis of hereditary and acquired disease.

See Mariam Mathew’s Curriculum Vitae (CV)

Awards, Honors & Organizations

Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award, Canadian Institutes of Health Research, 2009 Princess Margaret Hospital Foundation Graduate fellowship in Cancer Research, Dept. of Medical Biophysics, Univ. of Toronto, 2008 Invitation, Golden Key Honors Society, Univ. of Toronto, 2002 Fellow Member, American College of Medical Genetics, 2019 - Present Member, Association of Molecular Pathology, 2019 - Present

Research

Publications

                  Miller AR, Wijeratne S, McGrath SD, Schieffer KM, Miller KE, Lee K, Mathew M, LaHaye S, Fitch JR, Kelly BJ, White P, Mardis ER, Wilson RK, Cottrell CE, Magrini V. Pacific Biosciences Fusion and Long Isoform Pipeline for Cancer Transcriptome-Based Resolution of Isoform Complexity. J Mol Diagn. 2022 Sep 30;  

                


                  Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;  

                


                  Arredondo K, Myers C, Hansen-Kiss E, Mathew MT, Jayaraman V, Siemon A, Bartholomew D, Herman GE, Mori M. Phenotypic Spectrum in a Family Sharing a Heterozygous KCNQ3 Variant. J Child Neurol. 2022 Apr 6;  8830738221089741.

                


                  Melas M, Mathew MT, Mori M, Jayaraman V, Wilson SA, Martin C, Jacobson-Kelly AE, Kelly BJ, Magrini V, Mardis ER, Cottrell CE, Lee K. Somatic variation as an incidental finding in the pediatric next-generation sequencing era. Cold Spring Harb Mol Case Stud. 2021 Dec; 7: 

                


                  Li D, Wang Q, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Guillen Sacoto MJ, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala A, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez-Agosto JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y, Hakonarson H. Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. Sci Adv. 2021 May; 7: 

                


                  Garg S, Gernier S, Misyura M, Sukhai MA, Thomas M, Kamel-Reid S, Stockley T. Assessing the Diagnostic Yield of Targeted Next-Generation Sequencing for Melanoma and Gastrointestinal Tumors. J Mol Diagn. 2020 Feb 6;  

                


                  Sukhai MA, Misyura M, Thomas M, Garg S, Zhang T, Stickle N, Virtanen C, Bedard PL, Siu LL, Smets T, Thijs G, Van Vooren S, Kamel-Reid S, Stockley TL. Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels. J Mol Diagn. 2019 Mar; 21: 261-273.

                


                  Spiegel JY, McNamara C, Kennedy JA, Panzarella T, Arruda A, Stockley T, Sukhai M, Thomas M, Bartoszko J, Ho J, Siddiq N, Maze D, Schimmer A, Schuh A, Sibai H, Yee K, Claudio J, Devlin R, Minden MD, Kamel-Reid S, Gupta V. Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy. Blood Adv. 2017 Sep 12; 1: 1729-1738.

View More Publications

Education

Date of Appointment at Nationwide Children’s Hospital: 09/30/2019

Graduate School

UNIVERSITY OF TORONTO, FACULTY OF MEDICINE

Date Completed: 06/01/2013

Contact Information

Institute for Genomic Medicine

Call us at: (614) 355-3675

                    575 Children's CrossroadColumbus, OH 43215 (map)

Contact Information

Call us at: (614) 355-3675

Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)

Learn more about Mariam Mathew

Biography

Mariam Mathew, PhD, FACMG is a clinical director within the Institute for Genomic Medicine. She received her PhD at the University of Toronto, Canada where she focused on variant fusions in acute promyelocytic leukemia. Her interest in clinical diagnostics expanded through the course of her post-doctoral work at the University Health Network - Advanced Molecular Diagnostics Laboratory in Toronto, where she led the analytical validation and implementation process for a targeted Next Generation Sequencing panel for hematological malignancies, and contributed to designing a variant classification system directed at interpreting somatic variant profiles. In 2019, Dr. Mathew completed an ABMGG Laboratory Genetics and Genomics fellowship at the University of Chicago. Her interests focus on the application of cytogenetic and molecular techniques to understand the genetic basis of hereditary and acquired disease.

See Mariam Mathew’s Curriculum Vitae (CV)

Awards, Honors & Organizations

Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award, Canadian Institutes of Health Research, 2009 Princess Margaret Hospital Foundation Graduate fellowship in Cancer Research, Dept. of Medical Biophysics, Univ. of Toronto, 2008 Invitation, Golden Key Honors Society, Univ. of Toronto, 2002 Fellow Member, American College of Medical Genetics, 2019 - Present Member, Association of Molecular Pathology, 2019 - Present

Research

Publications

                  Miller AR, Wijeratne S, McGrath SD, Schieffer KM, Miller KE, Lee K, Mathew M, LaHaye S, Fitch JR, Kelly BJ, White P, Mardis ER, Wilson RK, Cottrell CE, Magrini V. Pacific Biosciences Fusion and Long Isoform Pipeline for Cancer Transcriptome-Based Resolution of Isoform Complexity. J Mol Diagn. 2022 Sep 30;  

                


                  Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;  

                


                  Arredondo K, Myers C, Hansen-Kiss E, Mathew MT, Jayaraman V, Siemon A, Bartholomew D, Herman GE, Mori M. Phenotypic Spectrum in a Family Sharing a Heterozygous KCNQ3 Variant. J Child Neurol. 2022 Apr 6;  8830738221089741.

                


                  Melas M, Mathew MT, Mori M, Jayaraman V, Wilson SA, Martin C, Jacobson-Kelly AE, Kelly BJ, Magrini V, Mardis ER, Cottrell CE, Lee K. Somatic variation as an incidental finding in the pediatric next-generation sequencing era. Cold Spring Harb Mol Case Stud. 2021 Dec; 7: 

                


                  Li D, Wang Q, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Guillen Sacoto MJ, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala A, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez-Agosto JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y, Hakonarson H. Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. Sci Adv. 2021 May; 7: 

                


                  Garg S, Gernier S, Misyura M, Sukhai MA, Thomas M, Kamel-Reid S, Stockley T. Assessing the Diagnostic Yield of Targeted Next-Generation Sequencing for Melanoma and Gastrointestinal Tumors. J Mol Diagn. 2020 Feb 6;  

                


                  Sukhai MA, Misyura M, Thomas M, Garg S, Zhang T, Stickle N, Virtanen C, Bedard PL, Siu LL, Smets T, Thijs G, Van Vooren S, Kamel-Reid S, Stockley TL. Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels. J Mol Diagn. 2019 Mar; 21: 261-273.

                


                  Spiegel JY, McNamara C, Kennedy JA, Panzarella T, Arruda A, Stockley T, Sukhai M, Thomas M, Bartoszko J, Ho J, Siddiq N, Maze D, Schimmer A, Schuh A, Sibai H, Yee K, Claudio J, Devlin R, Minden MD, Kamel-Reid S, Gupta V. Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy. Blood Adv. 2017 Sep 12; 1: 1729-1738.

View More Publications

Education

Date of Appointment at Nationwide Children’s Hospital: 09/30/2019

Graduate School

UNIVERSITY OF TORONTO, FACULTY OF MEDICINE

Date Completed: 06/01/2013

Contact Information

Institute for Genomic Medicine

Call us at: (614) 355-3675

                    575 Children's CrossroadColumbus, OH 43215 (map)

Contact Information

Call us at: (614) 355-3675

Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)

Learn more about Mariam Mathew

Contact Information

  • Call us at:
  • (614) 355-3675
  • Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)

Learn more about Mariam Mathew

Biography

Mariam Mathew, PhD, FACMG is a clinical director within the Institute for Genomic Medicine. She received her PhD at the University of Toronto, Canada where she focused on variant fusions in acute promyelocytic leukemia. Her interest in clinical diagnostics expanded through the course of her post-doctoral work at the University Health Network - Advanced Molecular Diagnostics Laboratory in Toronto, where she led the analytical validation and implementation process for a targeted Next Generation Sequencing panel for hematological malignancies, and contributed to designing a variant classification system directed at interpreting somatic variant profiles. In 2019, Dr. Mathew completed an ABMGG Laboratory Genetics and Genomics fellowship at the University of Chicago. Her interests focus on the application of cytogenetic and molecular techniques to understand the genetic basis of hereditary and acquired disease.

See Mariam Mathew’s Curriculum Vitae (CV)

Biography

Mariam Mathew, PhD, FACMG is a clinical director within the Institute for Genomic Medicine. She received her PhD at the University of Toronto, Canada where she focused on variant fusions in acute promyelocytic leukemia. Her interest in clinical diagnostics expanded through the course of her post-doctoral work at the University Health Network - Advanced Molecular Diagnostics Laboratory in Toronto, where she led the analytical validation and implementation process for a targeted Next Generation Sequencing panel for hematological malignancies, and contributed to designing a variant classification system directed at interpreting somatic variant profiles. In 2019, Dr. Mathew completed an ABMGG Laboratory Genetics and Genomics fellowship at the University of Chicago. Her interests focus on the application of cytogenetic and molecular techniques to understand the genetic basis of hereditary and acquired disease.

See Mariam Mathew’s Curriculum Vitae (CV)

Biography

Mariam Mathew, PhD, FACMG is a clinical director within the Institute for Genomic Medicine. She received her PhD at the University of Toronto, Canada where she focused on variant fusions in acute promyelocytic leukemia. Her interest in clinical diagnostics expanded through the course of her post-doctoral work at the University Health Network - Advanced Molecular Diagnostics Laboratory in Toronto, where she led the analytical validation and implementation process for a targeted Next Generation Sequencing panel for hematological malignancies, and contributed to designing a variant classification system directed at interpreting somatic variant profiles. In 2019, Dr. Mathew completed an ABMGG Laboratory Genetics and Genomics fellowship at the University of Chicago. Her interests focus on the application of cytogenetic and molecular techniques to understand the genetic basis of hereditary and acquired disease.

See Mariam Mathew’s Curriculum Vitae (CV)

Mariam Mathew, PhD, FACMG is a clinical director within the Institute for Genomic Medicine. She received her PhD at the University of Toronto, Canada where she focused on variant fusions in acute promyelocytic leukemia. Her interest in clinical diagnostics expanded through the course of her post-doctoral work at the University Health Network - Advanced Molecular Diagnostics Laboratory in Toronto, where she led the analytical validation and implementation process for a targeted Next Generation Sequencing panel for hematological malignancies, and contributed to designing a variant classification system directed at interpreting somatic variant profiles. In 2019, Dr. Mathew completed an ABMGG Laboratory Genetics and Genomics fellowship at the University of Chicago. Her interests focus on the application of cytogenetic and molecular techniques to understand the genetic basis of hereditary and acquired disease.

See Mariam Mathew’s Curriculum Vitae (CV)

Mariam Mathew, PhD, FACMG is a clinical director within the Institute for Genomic Medicine. She received her PhD at the University of Toronto, Canada where she focused on variant fusions in acute promyelocytic leukemia. Her interest in clinical diagnostics expanded through the course of her post-doctoral work at the University Health Network - Advanced Molecular Diagnostics Laboratory in Toronto, where she led the analytical validation and implementation process for a targeted Next Generation Sequencing panel for hematological malignancies, and contributed to designing a variant classification system directed at interpreting somatic variant profiles. In 2019, Dr. Mathew completed an ABMGG Laboratory Genetics and Genomics fellowship at the University of Chicago. Her interests focus on the application of cytogenetic and molecular techniques to understand the genetic basis of hereditary and acquired disease.

See Mariam Mathew’s Curriculum Vitae (CV)

Awards, Honors & Organizations

Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award, Canadian Institutes of Health Research, 2009 Princess Margaret Hospital Foundation Graduate fellowship in Cancer Research, Dept. of Medical Biophysics, Univ. of Toronto, 2008 Invitation, Golden Key Honors Society, Univ. of Toronto, 2002 Fellow Member, American College of Medical Genetics, 2019 - Present Member, Association of Molecular Pathology, 2019 - Present

Awards, Honors & Organizations

Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award, Canadian Institutes of Health Research, 2009 Princess Margaret Hospital Foundation Graduate fellowship in Cancer Research, Dept. of Medical Biophysics, Univ. of Toronto, 2008 Invitation, Golden Key Honors Society, Univ. of Toronto, 2002 Fellow Member, American College of Medical Genetics, 2019 - Present Member, Association of Molecular Pathology, 2019 - Present

Awards, Honors & Organizations

Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award, Canadian Institutes of Health Research, 2009 Princess Margaret Hospital Foundation Graduate fellowship in Cancer Research, Dept. of Medical Biophysics, Univ. of Toronto, 2008 Invitation, Golden Key Honors Society, Univ. of Toronto, 2002 Fellow Member, American College of Medical Genetics, 2019 - Present Member, Association of Molecular Pathology, 2019 - Present

Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award, Canadian Institutes of Health Research, 2009 Princess Margaret Hospital Foundation Graduate fellowship in Cancer Research, Dept. of Medical Biophysics, Univ. of Toronto, 2008 Invitation, Golden Key Honors Society, Univ. of Toronto, 2002 Fellow Member, American College of Medical Genetics, 2019 - Present Member, Association of Molecular Pathology, 2019 - Present

  • Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award, Canadian Institutes of Health Research, 2009
  • Princess Margaret Hospital Foundation Graduate fellowship in Cancer Research, Dept. of Medical Biophysics, Univ. of Toronto, 2008
  • Invitation, Golden Key Honors Society, Univ. of Toronto, 2002
  • Fellow Member, American College of Medical Genetics, 2019 - Present
  • Member, Association of Molecular Pathology, 2019 - Present

Research

Publications

                  Miller AR, Wijeratne S, McGrath SD, Schieffer KM, Miller KE, Lee K, Mathew M, LaHaye S, Fitch JR, Kelly BJ, White P, Mardis ER, Wilson RK, Cottrell CE, Magrini V. Pacific Biosciences Fusion and Long Isoform Pipeline for Cancer Transcriptome-Based Resolution of Isoform Complexity. J Mol Diagn. 2022 Sep 30;  

                


                  Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;  

                


                  Arredondo K, Myers C, Hansen-Kiss E, Mathew MT, Jayaraman V, Siemon A, Bartholomew D, Herman GE, Mori M. Phenotypic Spectrum in a Family Sharing a Heterozygous KCNQ3 Variant. J Child Neurol. 2022 Apr 6;  8830738221089741.

                


                  Melas M, Mathew MT, Mori M, Jayaraman V, Wilson SA, Martin C, Jacobson-Kelly AE, Kelly BJ, Magrini V, Mardis ER, Cottrell CE, Lee K. Somatic variation as an incidental finding in the pediatric next-generation sequencing era. Cold Spring Harb Mol Case Stud. 2021 Dec; 7: 

                


                  Li D, Wang Q, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Guillen Sacoto MJ, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala A, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez-Agosto JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y, Hakonarson H. Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. Sci Adv. 2021 May; 7: 

                


                  Garg S, Gernier S, Misyura M, Sukhai MA, Thomas M, Kamel-Reid S, Stockley T. Assessing the Diagnostic Yield of Targeted Next-Generation Sequencing for Melanoma and Gastrointestinal Tumors. J Mol Diagn. 2020 Feb 6;  

                


                  Sukhai MA, Misyura M, Thomas M, Garg S, Zhang T, Stickle N, Virtanen C, Bedard PL, Siu LL, Smets T, Thijs G, Van Vooren S, Kamel-Reid S, Stockley TL. Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels. J Mol Diagn. 2019 Mar; 21: 261-273.

                


                  Spiegel JY, McNamara C, Kennedy JA, Panzarella T, Arruda A, Stockley T, Sukhai M, Thomas M, Bartoszko J, Ho J, Siddiq N, Maze D, Schimmer A, Schuh A, Sibai H, Yee K, Claudio J, Devlin R, Minden MD, Kamel-Reid S, Gupta V. Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy. Blood Adv. 2017 Sep 12; 1: 1729-1738.

View More Publications

Research

Publications

                  Miller AR, Wijeratne S, McGrath SD, Schieffer KM, Miller KE, Lee K, Mathew M, LaHaye S, Fitch JR, Kelly BJ, White P, Mardis ER, Wilson RK, Cottrell CE, Magrini V. Pacific Biosciences Fusion and Long Isoform Pipeline for Cancer Transcriptome-Based Resolution of Isoform Complexity. J Mol Diagn. 2022 Sep 30;  

                


                  Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;  

                


                  Arredondo K, Myers C, Hansen-Kiss E, Mathew MT, Jayaraman V, Siemon A, Bartholomew D, Herman GE, Mori M. Phenotypic Spectrum in a Family Sharing a Heterozygous KCNQ3 Variant. J Child Neurol. 2022 Apr 6;  8830738221089741.

                


                  Melas M, Mathew MT, Mori M, Jayaraman V, Wilson SA, Martin C, Jacobson-Kelly AE, Kelly BJ, Magrini V, Mardis ER, Cottrell CE, Lee K. Somatic variation as an incidental finding in the pediatric next-generation sequencing era. Cold Spring Harb Mol Case Stud. 2021 Dec; 7: 

                


                  Li D, Wang Q, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Guillen Sacoto MJ, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala A, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez-Agosto JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y, Hakonarson H. Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. Sci Adv. 2021 May; 7: 

                


                  Garg S, Gernier S, Misyura M, Sukhai MA, Thomas M, Kamel-Reid S, Stockley T. Assessing the Diagnostic Yield of Targeted Next-Generation Sequencing for Melanoma and Gastrointestinal Tumors. J Mol Diagn. 2020 Feb 6;  

                


                  Sukhai MA, Misyura M, Thomas M, Garg S, Zhang T, Stickle N, Virtanen C, Bedard PL, Siu LL, Smets T, Thijs G, Van Vooren S, Kamel-Reid S, Stockley TL. Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels. J Mol Diagn. 2019 Mar; 21: 261-273.

                


                  Spiegel JY, McNamara C, Kennedy JA, Panzarella T, Arruda A, Stockley T, Sukhai M, Thomas M, Bartoszko J, Ho J, Siddiq N, Maze D, Schimmer A, Schuh A, Sibai H, Yee K, Claudio J, Devlin R, Minden MD, Kamel-Reid S, Gupta V. Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy. Blood Adv. 2017 Sep 12; 1: 1729-1738.

View More Publications

Research

Publications

                  Miller AR, Wijeratne S, McGrath SD, Schieffer KM, Miller KE, Lee K, Mathew M, LaHaye S, Fitch JR, Kelly BJ, White P, Mardis ER, Wilson RK, Cottrell CE, Magrini V. Pacific Biosciences Fusion and Long Isoform Pipeline for Cancer Transcriptome-Based Resolution of Isoform Complexity. J Mol Diagn. 2022 Sep 30;  

                


                  Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;  

                


                  Arredondo K, Myers C, Hansen-Kiss E, Mathew MT, Jayaraman V, Siemon A, Bartholomew D, Herman GE, Mori M. Phenotypic Spectrum in a Family Sharing a Heterozygous KCNQ3 Variant. J Child Neurol. 2022 Apr 6;  8830738221089741.

                


                  Melas M, Mathew MT, Mori M, Jayaraman V, Wilson SA, Martin C, Jacobson-Kelly AE, Kelly BJ, Magrini V, Mardis ER, Cottrell CE, Lee K. Somatic variation as an incidental finding in the pediatric next-generation sequencing era. Cold Spring Harb Mol Case Stud. 2021 Dec; 7: 

                


                  Li D, Wang Q, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Guillen Sacoto MJ, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala A, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez-Agosto JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y, Hakonarson H. Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. Sci Adv. 2021 May; 7: 

                


                  Garg S, Gernier S, Misyura M, Sukhai MA, Thomas M, Kamel-Reid S, Stockley T. Assessing the Diagnostic Yield of Targeted Next-Generation Sequencing for Melanoma and Gastrointestinal Tumors. J Mol Diagn. 2020 Feb 6;  

                


                  Sukhai MA, Misyura M, Thomas M, Garg S, Zhang T, Stickle N, Virtanen C, Bedard PL, Siu LL, Smets T, Thijs G, Van Vooren S, Kamel-Reid S, Stockley TL. Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels. J Mol Diagn. 2019 Mar; 21: 261-273.

                


                  Spiegel JY, McNamara C, Kennedy JA, Panzarella T, Arruda A, Stockley T, Sukhai M, Thomas M, Bartoszko J, Ho J, Siddiq N, Maze D, Schimmer A, Schuh A, Sibai H, Yee K, Claudio J, Devlin R, Minden MD, Kamel-Reid S, Gupta V. Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy. Blood Adv. 2017 Sep 12; 1: 1729-1738.

View More Publications

Publications

                  Miller AR, Wijeratne S, McGrath SD, Schieffer KM, Miller KE, Lee K, Mathew M, LaHaye S, Fitch JR, Kelly BJ, White P, Mardis ER, Wilson RK, Cottrell CE, Magrini V. Pacific Biosciences Fusion and Long Isoform Pipeline for Cancer Transcriptome-Based Resolution of Isoform Complexity. J Mol Diagn. 2022 Sep 30;  

                


                  Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;  

                


                  Arredondo K, Myers C, Hansen-Kiss E, Mathew MT, Jayaraman V, Siemon A, Bartholomew D, Herman GE, Mori M. Phenotypic Spectrum in a Family Sharing a Heterozygous KCNQ3 Variant. J Child Neurol. 2022 Apr 6;  8830738221089741.

                


                  Melas M, Mathew MT, Mori M, Jayaraman V, Wilson SA, Martin C, Jacobson-Kelly AE, Kelly BJ, Magrini V, Mardis ER, Cottrell CE, Lee K. Somatic variation as an incidental finding in the pediatric next-generation sequencing era. Cold Spring Harb Mol Case Stud. 2021 Dec; 7: 

                


                  Li D, Wang Q, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Guillen Sacoto MJ, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala A, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez-Agosto JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y, Hakonarson H. Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. Sci Adv. 2021 May; 7: 

                


                  Garg S, Gernier S, Misyura M, Sukhai MA, Thomas M, Kamel-Reid S, Stockley T. Assessing the Diagnostic Yield of Targeted Next-Generation Sequencing for Melanoma and Gastrointestinal Tumors. J Mol Diagn. 2020 Feb 6;  

                


                  Sukhai MA, Misyura M, Thomas M, Garg S, Zhang T, Stickle N, Virtanen C, Bedard PL, Siu LL, Smets T, Thijs G, Van Vooren S, Kamel-Reid S, Stockley TL. Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels. J Mol Diagn. 2019 Mar; 21: 261-273.

                


                  Spiegel JY, McNamara C, Kennedy JA, Panzarella T, Arruda A, Stockley T, Sukhai M, Thomas M, Bartoszko J, Ho J, Siddiq N, Maze D, Schimmer A, Schuh A, Sibai H, Yee K, Claudio J, Devlin R, Minden MD, Kamel-Reid S, Gupta V. Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy. Blood Adv. 2017 Sep 12; 1: 1729-1738.

View More Publications

                  Miller AR, Wijeratne S, McGrath SD, Schieffer KM, Miller KE, Lee K, Mathew M, LaHaye S, Fitch JR, Kelly BJ, White P, Mardis ER, Wilson RK, Cottrell CE, Magrini V. Pacific Biosciences Fusion and Long Isoform Pipeline for Cancer Transcriptome-Based Resolution of Isoform Complexity. J Mol Diagn. 2022 Sep 30;  

                


                  Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;  

                


                  Arredondo K, Myers C, Hansen-Kiss E, Mathew MT, Jayaraman V, Siemon A, Bartholomew D, Herman GE, Mori M. Phenotypic Spectrum in a Family Sharing a Heterozygous KCNQ3 Variant. J Child Neurol. 2022 Apr 6;  8830738221089741.

                


                  Melas M, Mathew MT, Mori M, Jayaraman V, Wilson SA, Martin C, Jacobson-Kelly AE, Kelly BJ, Magrini V, Mardis ER, Cottrell CE, Lee K. Somatic variation as an incidental finding in the pediatric next-generation sequencing era. Cold Spring Harb Mol Case Stud. 2021 Dec; 7: 

                


                  Li D, Wang Q, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Guillen Sacoto MJ, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala A, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez-Agosto JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y, Hakonarson H. Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. Sci Adv. 2021 May; 7: 

                


                  Garg S, Gernier S, Misyura M, Sukhai MA, Thomas M, Kamel-Reid S, Stockley T. Assessing the Diagnostic Yield of Targeted Next-Generation Sequencing for Melanoma and Gastrointestinal Tumors. J Mol Diagn. 2020 Feb 6;  

                


                  Sukhai MA, Misyura M, Thomas M, Garg S, Zhang T, Stickle N, Virtanen C, Bedard PL, Siu LL, Smets T, Thijs G, Van Vooren S, Kamel-Reid S, Stockley TL. Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels. J Mol Diagn. 2019 Mar; 21: 261-273.

                


                  Spiegel JY, McNamara C, Kennedy JA, Panzarella T, Arruda A, Stockley T, Sukhai M, Thomas M, Bartoszko J, Ho J, Siddiq N, Maze D, Schimmer A, Schuh A, Sibai H, Yee K, Claudio J, Devlin R, Minden MD, Kamel-Reid S, Gupta V. Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy. Blood Adv. 2017 Sep 12; 1: 1729-1738.

View More Publications

  • Miller AR, Wijeratne S, McGrath SD, Schieffer KM, Miller KE, Lee K, Mathew M, LaHaye S, Fitch JR, Kelly BJ, White P, Mardis ER, Wilson RK, Cottrell CE, Magrini V. Pacific Biosciences Fusion and Long Isoform Pipeline for Cancer Transcriptome-Based Resolution of Isoform Complexity. J Mol Diagn. 2022 Sep 30;
  • Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade’s Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;
  • Arredondo K, Myers C, Hansen-Kiss E, Mathew MT, Jayaraman V, Siemon A, Bartholomew D, Herman GE, Mori M. Phenotypic Spectrum in a Family Sharing a Heterozygous KCNQ3 Variant. J Child Neurol. 2022 Apr 6; 8830738221089741.
  • Melas M, Mathew MT, Mori M, Jayaraman V, Wilson SA, Martin C, Jacobson-Kelly AE, Kelly BJ, Magrini V, Mardis ER, Cottrell CE, Lee K. Somatic variation as an incidental finding in the pediatric next-generation sequencing era. Cold Spring Harb Mol Case Stud. 2021 Dec; 7:
  • Li D, Wang Q, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Guillen Sacoto MJ, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala A, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez-Agosto JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y, Hakonarson H. Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. Sci Adv. 2021 May; 7:
  • Garg S, Gernier S, Misyura M, Sukhai MA, Thomas M, Kamel-Reid S, Stockley T. Assessing the Diagnostic Yield of Targeted Next-Generation Sequencing for Melanoma and Gastrointestinal Tumors. J Mol Diagn. 2020 Feb 6;
  • Sukhai MA, Misyura M, Thomas M, Garg S, Zhang T, Stickle N, Virtanen C, Bedard PL, Siu LL, Smets T, Thijs G, Van Vooren S, Kamel-Reid S, Stockley TL. Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels. J Mol Diagn. 2019 Mar; 21: 261-273.
  • Spiegel JY, McNamara C, Kennedy JA, Panzarella T, Arruda A, Stockley T, Sukhai M, Thomas M, Bartoszko J, Ho J, Siddiq N, Maze D, Schimmer A, Schuh A, Sibai H, Yee K, Claudio J, Devlin R, Minden MD, Kamel-Reid S, Gupta V. Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy. Blood Adv. 2017 Sep 12; 1: 1729-1738.

Education

Date of Appointment at Nationwide Children’s Hospital: 09/30/2019

Graduate School

UNIVERSITY OF TORONTO, FACULTY OF MEDICINE

Date Completed: 06/01/2013

Education

Date of Appointment at Nationwide Children’s Hospital: 09/30/2019

Graduate School

UNIVERSITY OF TORONTO, FACULTY OF MEDICINE

Date Completed: 06/01/2013

Education

Date of Appointment at Nationwide Children’s Hospital: 09/30/2019

Graduate School

UNIVERSITY OF TORONTO, FACULTY OF MEDICINE

Date Completed: 06/01/2013

Date of Appointment at Nationwide Children’s Hospital: 09/30/2019

Graduate School

UNIVERSITY OF TORONTO, FACULTY OF MEDICINE

Date Completed: 06/01/2013

Date of Appointment at Nationwide Children’s Hospital: 09/30/2019

Graduate School

UNIVERSITY OF TORONTO, FACULTY OF MEDICINE

Date Completed: 06/01/2013

Contact Information

Institute for Genomic Medicine

Call us at: (614) 355-3675

                    575 Children's CrossroadColumbus, OH 43215 (map)

Contact Information

Institute for Genomic Medicine

Call us at: (614) 355-3675

                    575 Children's CrossroadColumbus, OH 43215 (map)

Contact Information

Institute for Genomic Medicine

Call us at: (614) 355-3675

                    575 Children's CrossroadColumbus, OH 43215 (map)

Institute for Genomic Medicine

Call us at: (614) 355-3675

                    575 Children's CrossroadColumbus, OH 43215 (map)

Call us at: (614) 355-3675

                    575 Children's CrossroadColumbus, OH 43215 (map)

Call us at: (614) 355-3675

                    575 Children's CrossroadColumbus, OH 43215 (map)
  • Call us at:
  • (614) 355-3675
  • 575 Children’s CrossroadColumbus, OH 43215 (map)