Contact Information
Call us at: (614) 355-5839
Email Marco L. Leung, PhD, FACMG
The Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)
Learn more about Marco L. Leung
Biography
Marco L. Leung, PhD, FACMG, is a clinical director within the Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital. He is an Assistant Professor - Clinical at the Department of Pathology at the Ohio State University College of Medicine. He is certified in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics (ABMGG). He finished his PhD studies under the supervision of Nicholas Navin, PhD, at The University of Texas MD Anderson Cancer Center. He then completed his ABMGG fellowship at The University of Chicago. He then served as the Assistant Director at Center for Applied Genomics (CAG) at Children’s Hospital of Philadelphia for two years. During his time at CAG, he helped to launch a carrier screening program for common and rare genetic diseases, as well as a pharmacogenetic screening test. Currently at IGM, he is actively involved in molecular genetic testing. His current research emphases include exome reanalysis, carrier screening, and molecular test development.
Awards, Honors & Organizations
Fellow, American College of Medical Genetics and Genomics, 2019 - Present Diplomate, American Board of Medical Genetics and Genomics, 2019 - Present
Research
Publications
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 Sep; 24: 1992.
Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee. Electronic address: documents@acmg.net.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 May 10;
Shao J, Gao L, Leung ML, Gallinger B, Inglese C, Meyn MS, Del Gaudio D, Das S, Li Z. Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma. Hematol Oncol. 2022 May 25;
Leung ML, Ji J, Baker S, Buchan JG, Sivakumaran TA, Krock BL, Hutchins R, Bayrak-Toydemir P, Pfeifer J, Cremona ML, Funke B, Santani AB. A Framework of Critical Considerations in Clinical Exome Reanalyses by Clinical and Laboratory Standards Institute. J Mol Diagn. 2022 Feb; 24: 177-188.
Ji J, Leung ML, Baker S, Deignan JL, Santani A. Clinical Exome Reanalysis: Current Practice and Beyond. Mol Diagn Ther. 2021 Sep; 25: 529-536.
Leung ML, McAdoo S, Watson D, Stumm K, Harr M, Wang X, Chung CH, Mafra F, Nesbitt AI, Hakonarson H, Santani A. A Transparent Approach to Calculate Detection Rate and Residual Risk for Carrier Screening. J Mol Diagn. 2021 Jan; 23: 91-102.
Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JS. Transient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 Nov 16; 11: 5799.
Pena LDM, Jiang YH, Schoch K, Spillmann RC, Walley N, Stong N, Rapisardo Horn S, Sullivan JA, McConkie-Rosell A, Kansagra S, Smith EC, El-Dairi M, Bellet J, Keels MA, Jasien J, Kranz PG, Noel R, Nagaraj SK, Lark RK, Wechsler DSG, Del Gaudio D, Leung ML, Hendon LG, Parker CC, Jones KL, Undiagnosed Diseases Network Members., Goldstein DB, Shashi V. Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. Genet Med. 2018 Apr; 20: 464-469.
Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin NE. Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Res. 2017 Aug; 27: 1287-1299.
View More Publications
Education
Date of Appointment at Nationwide Children’s Hospital: 05/11/2020
Fellowship
The University of Chicago
Date Completed: 06/30/2018
Graduate School
The University of Texas MD Anderson Cancer Center
Date Completed: 05/30/2016
Professional Experience
2020 - Present Nationwide Children’s Hospital2018 - Present Children’s Hospital of Philadelphia - Center for Applied Genomics, Assistant Director
Contact Information
The Institute for Genomic Medicine
Call us at: (614) 355-5839
Email Marco L Leung
575 Children's CrossroadColumbus, OH 43215 (map)
Connect with Marco L. Leung
Connect on Twitter
Contact Information
Call us at: (614) 355-5839
Email Marco L. Leung, PhD, FACMG
The Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)
Learn more about Marco L. Leung
Biography
Marco L. Leung, PhD, FACMG, is a clinical director within the Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital. He is an Assistant Professor - Clinical at the Department of Pathology at the Ohio State University College of Medicine. He is certified in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics (ABMGG). He finished his PhD studies under the supervision of Nicholas Navin, PhD, at The University of Texas MD Anderson Cancer Center. He then completed his ABMGG fellowship at The University of Chicago. He then served as the Assistant Director at Center for Applied Genomics (CAG) at Children’s Hospital of Philadelphia for two years. During his time at CAG, he helped to launch a carrier screening program for common and rare genetic diseases, as well as a pharmacogenetic screening test. Currently at IGM, he is actively involved in molecular genetic testing. His current research emphases include exome reanalysis, carrier screening, and molecular test development.
Awards, Honors & Organizations
Fellow, American College of Medical Genetics and Genomics, 2019 - Present Diplomate, American Board of Medical Genetics and Genomics, 2019 - Present
Research
Publications
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 Sep; 24: 1992.
Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee. Electronic address: documents@acmg.net.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 May 10;
Shao J, Gao L, Leung ML, Gallinger B, Inglese C, Meyn MS, Del Gaudio D, Das S, Li Z. Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma. Hematol Oncol. 2022 May 25;
Leung ML, Ji J, Baker S, Buchan JG, Sivakumaran TA, Krock BL, Hutchins R, Bayrak-Toydemir P, Pfeifer J, Cremona ML, Funke B, Santani AB. A Framework of Critical Considerations in Clinical Exome Reanalyses by Clinical and Laboratory Standards Institute. J Mol Diagn. 2022 Feb; 24: 177-188.
Ji J, Leung ML, Baker S, Deignan JL, Santani A. Clinical Exome Reanalysis: Current Practice and Beyond. Mol Diagn Ther. 2021 Sep; 25: 529-536.
Leung ML, McAdoo S, Watson D, Stumm K, Harr M, Wang X, Chung CH, Mafra F, Nesbitt AI, Hakonarson H, Santani A. A Transparent Approach to Calculate Detection Rate and Residual Risk for Carrier Screening. J Mol Diagn. 2021 Jan; 23: 91-102.
Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JS. Transient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 Nov 16; 11: 5799.
Pena LDM, Jiang YH, Schoch K, Spillmann RC, Walley N, Stong N, Rapisardo Horn S, Sullivan JA, McConkie-Rosell A, Kansagra S, Smith EC, El-Dairi M, Bellet J, Keels MA, Jasien J, Kranz PG, Noel R, Nagaraj SK, Lark RK, Wechsler DSG, Del Gaudio D, Leung ML, Hendon LG, Parker CC, Jones KL, Undiagnosed Diseases Network Members., Goldstein DB, Shashi V. Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. Genet Med. 2018 Apr; 20: 464-469.
Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin NE. Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Res. 2017 Aug; 27: 1287-1299.
View More Publications
Education
Date of Appointment at Nationwide Children’s Hospital: 05/11/2020
Fellowship
The University of Chicago
Date Completed: 06/30/2018
Graduate School
The University of Texas MD Anderson Cancer Center
Date Completed: 05/30/2016
Professional Experience
2020 - Present Nationwide Children’s Hospital2018 - Present Children’s Hospital of Philadelphia - Center for Applied Genomics, Assistant Director
Contact Information
The Institute for Genomic Medicine
Call us at: (614) 355-5839
Email Marco L Leung
575 Children's CrossroadColumbus, OH 43215 (map)
Connect with Marco L. Leung
Connect on Twitter
Contact Information
Call us at: (614) 355-5839
Email Marco L. Leung, PhD, FACMG
The Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)
Learn more about Marco L. Leung
Contact Information
- Call us at:
- (614) 355-5839
- Email Marco L. Leung, PhD, FACMG
- The Institute for Genomic Medicine575 Children’s CrossroadColumbus, OH 43215 (map)
Learn more about Marco L. Leung
Biography
Marco L. Leung, PhD, FACMG, is a clinical director within the Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital. He is an Assistant Professor - Clinical at the Department of Pathology at the Ohio State University College of Medicine. He is certified in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics (ABMGG). He finished his PhD studies under the supervision of Nicholas Navin, PhD, at The University of Texas MD Anderson Cancer Center. He then completed his ABMGG fellowship at The University of Chicago. He then served as the Assistant Director at Center for Applied Genomics (CAG) at Children’s Hospital of Philadelphia for two years. During his time at CAG, he helped to launch a carrier screening program for common and rare genetic diseases, as well as a pharmacogenetic screening test. Currently at IGM, he is actively involved in molecular genetic testing. His current research emphases include exome reanalysis, carrier screening, and molecular test development.
Biography
Marco L. Leung, PhD, FACMG, is a clinical director within the Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital. He is an Assistant Professor - Clinical at the Department of Pathology at the Ohio State University College of Medicine. He is certified in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics (ABMGG). He finished his PhD studies under the supervision of Nicholas Navin, PhD, at The University of Texas MD Anderson Cancer Center. He then completed his ABMGG fellowship at The University of Chicago. He then served as the Assistant Director at Center for Applied Genomics (CAG) at Children’s Hospital of Philadelphia for two years. During his time at CAG, he helped to launch a carrier screening program for common and rare genetic diseases, as well as a pharmacogenetic screening test. Currently at IGM, he is actively involved in molecular genetic testing. His current research emphases include exome reanalysis, carrier screening, and molecular test development.
Biography
Marco L. Leung, PhD, FACMG, is a clinical director within the Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital. He is an Assistant Professor - Clinical at the Department of Pathology at the Ohio State University College of Medicine. He is certified in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics (ABMGG). He finished his PhD studies under the supervision of Nicholas Navin, PhD, at The University of Texas MD Anderson Cancer Center. He then completed his ABMGG fellowship at The University of Chicago. He then served as the Assistant Director at Center for Applied Genomics (CAG) at Children’s Hospital of Philadelphia for two years. During his time at CAG, he helped to launch a carrier screening program for common and rare genetic diseases, as well as a pharmacogenetic screening test. Currently at IGM, he is actively involved in molecular genetic testing. His current research emphases include exome reanalysis, carrier screening, and molecular test development.
Marco L. Leung, PhD, FACMG, is a clinical director within the Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital. He is an Assistant Professor - Clinical at the Department of Pathology at the Ohio State University College of Medicine. He is certified in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics (ABMGG). He finished his PhD studies under the supervision of Nicholas Navin, PhD, at The University of Texas MD Anderson Cancer Center. He then completed his ABMGG fellowship at The University of Chicago. He then served as the Assistant Director at Center for Applied Genomics (CAG) at Children’s Hospital of Philadelphia for two years. During his time at CAG, he helped to launch a carrier screening program for common and rare genetic diseases, as well as a pharmacogenetic screening test. Currently at IGM, he is actively involved in molecular genetic testing. His current research emphases include exome reanalysis, carrier screening, and molecular test development.
Marco L. Leung, PhD, FACMG, is a clinical director within the Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital. He is an Assistant Professor - Clinical at the Department of Pathology at the Ohio State University College of Medicine. He is certified in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics (ABMGG). He finished his PhD studies under the supervision of Nicholas Navin, PhD, at The University of Texas MD Anderson Cancer Center. He then completed his ABMGG fellowship at The University of Chicago. He then served as the Assistant Director at Center for Applied Genomics (CAG) at Children’s Hospital of Philadelphia for two years. During his time at CAG, he helped to launch a carrier screening program for common and rare genetic diseases, as well as a pharmacogenetic screening test. Currently at IGM, he is actively involved in molecular genetic testing. His current research emphases include exome reanalysis, carrier screening, and molecular test development.
Awards, Honors & Organizations
Fellow, American College of Medical Genetics and Genomics, 2019 - Present Diplomate, American Board of Medical Genetics and Genomics, 2019 - Present
Awards, Honors & Organizations
Fellow, American College of Medical Genetics and Genomics, 2019 - Present Diplomate, American Board of Medical Genetics and Genomics, 2019 - Present
Awards, Honors & Organizations
Fellow, American College of Medical Genetics and Genomics, 2019 - Present Diplomate, American Board of Medical Genetics and Genomics, 2019 - Present
Fellow, American College of Medical Genetics and Genomics, 2019 - Present Diplomate, American Board of Medical Genetics and Genomics, 2019 - Present
- Fellow, American College of Medical Genetics and Genomics, 2019 - Present
- Diplomate, American Board of Medical Genetics and Genomics, 2019 - Present
Research
Publications
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 Sep; 24: 1992.
Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee. Electronic address: documents@acmg.net.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 May 10;
Shao J, Gao L, Leung ML, Gallinger B, Inglese C, Meyn MS, Del Gaudio D, Das S, Li Z. Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma. Hematol Oncol. 2022 May 25;
Leung ML, Ji J, Baker S, Buchan JG, Sivakumaran TA, Krock BL, Hutchins R, Bayrak-Toydemir P, Pfeifer J, Cremona ML, Funke B, Santani AB. A Framework of Critical Considerations in Clinical Exome Reanalyses by Clinical and Laboratory Standards Institute. J Mol Diagn. 2022 Feb; 24: 177-188.
Ji J, Leung ML, Baker S, Deignan JL, Santani A. Clinical Exome Reanalysis: Current Practice and Beyond. Mol Diagn Ther. 2021 Sep; 25: 529-536.
Leung ML, McAdoo S, Watson D, Stumm K, Harr M, Wang X, Chung CH, Mafra F, Nesbitt AI, Hakonarson H, Santani A. A Transparent Approach to Calculate Detection Rate and Residual Risk for Carrier Screening. J Mol Diagn. 2021 Jan; 23: 91-102.
Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JS. Transient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 Nov 16; 11: 5799.
Pena LDM, Jiang YH, Schoch K, Spillmann RC, Walley N, Stong N, Rapisardo Horn S, Sullivan JA, McConkie-Rosell A, Kansagra S, Smith EC, El-Dairi M, Bellet J, Keels MA, Jasien J, Kranz PG, Noel R, Nagaraj SK, Lark RK, Wechsler DSG, Del Gaudio D, Leung ML, Hendon LG, Parker CC, Jones KL, Undiagnosed Diseases Network Members., Goldstein DB, Shashi V. Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. Genet Med. 2018 Apr; 20: 464-469.
Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin NE. Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Res. 2017 Aug; 27: 1287-1299.
View More Publications
Research
Publications
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 Sep; 24: 1992.
Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee. Electronic address: documents@acmg.net.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 May 10;
Shao J, Gao L, Leung ML, Gallinger B, Inglese C, Meyn MS, Del Gaudio D, Das S, Li Z. Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma. Hematol Oncol. 2022 May 25;
Leung ML, Ji J, Baker S, Buchan JG, Sivakumaran TA, Krock BL, Hutchins R, Bayrak-Toydemir P, Pfeifer J, Cremona ML, Funke B, Santani AB. A Framework of Critical Considerations in Clinical Exome Reanalyses by Clinical and Laboratory Standards Institute. J Mol Diagn. 2022 Feb; 24: 177-188.
Ji J, Leung ML, Baker S, Deignan JL, Santani A. Clinical Exome Reanalysis: Current Practice and Beyond. Mol Diagn Ther. 2021 Sep; 25: 529-536.
Leung ML, McAdoo S, Watson D, Stumm K, Harr M, Wang X, Chung CH, Mafra F, Nesbitt AI, Hakonarson H, Santani A. A Transparent Approach to Calculate Detection Rate and Residual Risk for Carrier Screening. J Mol Diagn. 2021 Jan; 23: 91-102.
Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JS. Transient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 Nov 16; 11: 5799.
Pena LDM, Jiang YH, Schoch K, Spillmann RC, Walley N, Stong N, Rapisardo Horn S, Sullivan JA, McConkie-Rosell A, Kansagra S, Smith EC, El-Dairi M, Bellet J, Keels MA, Jasien J, Kranz PG, Noel R, Nagaraj SK, Lark RK, Wechsler DSG, Del Gaudio D, Leung ML, Hendon LG, Parker CC, Jones KL, Undiagnosed Diseases Network Members., Goldstein DB, Shashi V. Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. Genet Med. 2018 Apr; 20: 464-469.
Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin NE. Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Res. 2017 Aug; 27: 1287-1299.
View More Publications
Research
Publications
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 Sep; 24: 1992.
Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee. Electronic address: documents@acmg.net.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 May 10;
Shao J, Gao L, Leung ML, Gallinger B, Inglese C, Meyn MS, Del Gaudio D, Das S, Li Z. Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma. Hematol Oncol. 2022 May 25;
Leung ML, Ji J, Baker S, Buchan JG, Sivakumaran TA, Krock BL, Hutchins R, Bayrak-Toydemir P, Pfeifer J, Cremona ML, Funke B, Santani AB. A Framework of Critical Considerations in Clinical Exome Reanalyses by Clinical and Laboratory Standards Institute. J Mol Diagn. 2022 Feb; 24: 177-188.
Ji J, Leung ML, Baker S, Deignan JL, Santani A. Clinical Exome Reanalysis: Current Practice and Beyond. Mol Diagn Ther. 2021 Sep; 25: 529-536.
Leung ML, McAdoo S, Watson D, Stumm K, Harr M, Wang X, Chung CH, Mafra F, Nesbitt AI, Hakonarson H, Santani A. A Transparent Approach to Calculate Detection Rate and Residual Risk for Carrier Screening. J Mol Diagn. 2021 Jan; 23: 91-102.
Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JS. Transient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 Nov 16; 11: 5799.
Pena LDM, Jiang YH, Schoch K, Spillmann RC, Walley N, Stong N, Rapisardo Horn S, Sullivan JA, McConkie-Rosell A, Kansagra S, Smith EC, El-Dairi M, Bellet J, Keels MA, Jasien J, Kranz PG, Noel R, Nagaraj SK, Lark RK, Wechsler DSG, Del Gaudio D, Leung ML, Hendon LG, Parker CC, Jones KL, Undiagnosed Diseases Network Members., Goldstein DB, Shashi V. Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. Genet Med. 2018 Apr; 20: 464-469.
Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin NE. Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Res. 2017 Aug; 27: 1287-1299.
View More Publications
Publications
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 Sep; 24: 1992.
Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee. Electronic address: documents@acmg.net.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 May 10;
Shao J, Gao L, Leung ML, Gallinger B, Inglese C, Meyn MS, Del Gaudio D, Das S, Li Z. Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma. Hematol Oncol. 2022 May 25;
Leung ML, Ji J, Baker S, Buchan JG, Sivakumaran TA, Krock BL, Hutchins R, Bayrak-Toydemir P, Pfeifer J, Cremona ML, Funke B, Santani AB. A Framework of Critical Considerations in Clinical Exome Reanalyses by Clinical and Laboratory Standards Institute. J Mol Diagn. 2022 Feb; 24: 177-188.
Ji J, Leung ML, Baker S, Deignan JL, Santani A. Clinical Exome Reanalysis: Current Practice and Beyond. Mol Diagn Ther. 2021 Sep; 25: 529-536.
Leung ML, McAdoo S, Watson D, Stumm K, Harr M, Wang X, Chung CH, Mafra F, Nesbitt AI, Hakonarson H, Santani A. A Transparent Approach to Calculate Detection Rate and Residual Risk for Carrier Screening. J Mol Diagn. 2021 Jan; 23: 91-102.
Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JS. Transient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 Nov 16; 11: 5799.
Pena LDM, Jiang YH, Schoch K, Spillmann RC, Walley N, Stong N, Rapisardo Horn S, Sullivan JA, McConkie-Rosell A, Kansagra S, Smith EC, El-Dairi M, Bellet J, Keels MA, Jasien J, Kranz PG, Noel R, Nagaraj SK, Lark RK, Wechsler DSG, Del Gaudio D, Leung ML, Hendon LG, Parker CC, Jones KL, Undiagnosed Diseases Network Members., Goldstein DB, Shashi V. Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. Genet Med. 2018 Apr; 20: 464-469.
Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin NE. Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Res. 2017 Aug; 27: 1287-1299.
View More Publications
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 Sep; 24: 1992.
Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;
Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee. Electronic address: documents@acmg.net.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 May 10;
Shao J, Gao L, Leung ML, Gallinger B, Inglese C, Meyn MS, Del Gaudio D, Das S, Li Z. Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma. Hematol Oncol. 2022 May 25;
Leung ML, Ji J, Baker S, Buchan JG, Sivakumaran TA, Krock BL, Hutchins R, Bayrak-Toydemir P, Pfeifer J, Cremona ML, Funke B, Santani AB. A Framework of Critical Considerations in Clinical Exome Reanalyses by Clinical and Laboratory Standards Institute. J Mol Diagn. 2022 Feb; 24: 177-188.
Ji J, Leung ML, Baker S, Deignan JL, Santani A. Clinical Exome Reanalysis: Current Practice and Beyond. Mol Diagn Ther. 2021 Sep; 25: 529-536.
Leung ML, McAdoo S, Watson D, Stumm K, Harr M, Wang X, Chung CH, Mafra F, Nesbitt AI, Hakonarson H, Santani A. A Transparent Approach to Calculate Detection Rate and Residual Risk for Carrier Screening. J Mol Diagn. 2021 Jan; 23: 91-102.
Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JS. Transient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 Nov 16; 11: 5799.
Pena LDM, Jiang YH, Schoch K, Spillmann RC, Walley N, Stong N, Rapisardo Horn S, Sullivan JA, McConkie-Rosell A, Kansagra S, Smith EC, El-Dairi M, Bellet J, Keels MA, Jasien J, Kranz PG, Noel R, Nagaraj SK, Lark RK, Wechsler DSG, Del Gaudio D, Leung ML, Hendon LG, Parker CC, Jones KL, Undiagnosed Diseases Network Members., Goldstein DB, Shashi V. Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. Genet Med. 2018 Apr; 20: 464-469.
Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin NE. Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Res. 2017 Aug; 27: 1287-1299.
View More Publications
- Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 Sep; 24: 1992.
- Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung ML. A Decade’s Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 Jun 16;
- Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D, Leung ML, ACMG Professional Practice and Guidelines Committee. Electronic address: documents@acmg.net.. Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med. 2022 May 10;
- Shao J, Gao L, Leung ML, Gallinger B, Inglese C, Meyn MS, Del Gaudio D, Das S, Li Z. Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma. Hematol Oncol. 2022 May 25;
- Leung ML, Ji J, Baker S, Buchan JG, Sivakumaran TA, Krock BL, Hutchins R, Bayrak-Toydemir P, Pfeifer J, Cremona ML, Funke B, Santani AB. A Framework of Critical Considerations in Clinical Exome Reanalyses by Clinical and Laboratory Standards Institute. J Mol Diagn. 2022 Feb; 24: 177-188.
- Ji J, Leung ML, Baker S, Deignan JL, Santani A. Clinical Exome Reanalysis: Current Practice and Beyond. Mol Diagn Ther. 2021 Sep; 25: 529-536.
- Leung ML, McAdoo S, Watson D, Stumm K, Harr M, Wang X, Chung CH, Mafra F, Nesbitt AI, Hakonarson H, Santani A. A Transparent Approach to Calculate Detection Rate and Residual Risk for Carrier Screening. J Mol Diagn. 2021 Jan; 23: 91-102.
- Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JS. Transient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 Nov 16; 11: 5799.
- Pena LDM, Jiang YH, Schoch K, Spillmann RC, Walley N, Stong N, Rapisardo Horn S, Sullivan JA, McConkie-Rosell A, Kansagra S, Smith EC, El-Dairi M, Bellet J, Keels MA, Jasien J, Kranz PG, Noel R, Nagaraj SK, Lark RK, Wechsler DSG, Del Gaudio D, Leung ML, Hendon LG, Parker CC, Jones KL, Undiagnosed Diseases Network Members., Goldstein DB, Shashi V. Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. Genet Med. 2018 Apr; 20: 464-469.
- Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin NE. Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Res. 2017 Aug; 27: 1287-1299.
Education
Date of Appointment at Nationwide Children’s Hospital: 05/11/2020
Fellowship
The University of Chicago
Date Completed: 06/30/2018
Graduate School
The University of Texas MD Anderson Cancer Center
Date Completed: 05/30/2016
Education
Date of Appointment at Nationwide Children’s Hospital: 05/11/2020
Fellowship
The University of Chicago
Date Completed: 06/30/2018
Graduate School
The University of Texas MD Anderson Cancer Center
Date Completed: 05/30/2016
Education
Date of Appointment at Nationwide Children’s Hospital: 05/11/2020
Fellowship
The University of Chicago
Date Completed: 06/30/2018
Graduate School
The University of Texas MD Anderson Cancer Center
Date Completed: 05/30/2016
Date of Appointment at Nationwide Children’s Hospital: 05/11/2020
Fellowship
The University of Chicago
Date Completed: 06/30/2018
Graduate School
The University of Texas MD Anderson Cancer Center
Date Completed: 05/30/2016
Date of Appointment at Nationwide Children’s Hospital: 05/11/2020
Fellowship
The University of Chicago
Date Completed: 06/30/2018
Graduate School
The University of Texas MD Anderson Cancer Center
Date Completed: 05/30/2016
Professional Experience
2020 - Present Nationwide Children’s Hospital2018 - Present Children’s Hospital of Philadelphia - Center for Applied Genomics, Assistant Director
Professional Experience
2020 - Present Nationwide Children’s Hospital2018 - Present Children’s Hospital of Philadelphia - Center for Applied Genomics, Assistant Director
Professional Experience
2020 - Present Nationwide Children’s Hospital2018 - Present Children’s Hospital of Philadelphia - Center for Applied Genomics, Assistant Director
2020 - Present Nationwide Children’s Hospital2018 - Present Children’s Hospital of Philadelphia - Center for Applied Genomics, Assistant Director
2020 - Present Nationwide Children’s Hospital
Contact Information
The Institute for Genomic Medicine
Call us at: (614) 355-5839
Email Marco L Leung
575 Children's CrossroadColumbus, OH 43215 (map)
Contact Information
The Institute for Genomic Medicine
Call us at: (614) 355-5839
Email Marco L Leung
575 Children's CrossroadColumbus, OH 43215 (map)
Contact Information
The Institute for Genomic Medicine
Call us at: (614) 355-5839
Email Marco L Leung
575 Children's CrossroadColumbus, OH 43215 (map)
The Institute for Genomic Medicine
Call us at: (614) 355-5839
Email Marco L Leung
575 Children's CrossroadColumbus, OH 43215 (map)
Call us at: (614) 355-5839
Email Marco L Leung
575 Children's CrossroadColumbus, OH 43215 (map)
Call us at: (614) 355-5839
Email Marco L Leung
575 Children's CrossroadColumbus, OH 43215 (map)
- Call us at:
- (614) 355-5839
- Email Marco L Leung
- 575 Children’s CrossroadColumbus, OH 43215 (map)
Connect with Marco L. Leung
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