Contact Information
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
PediatricsNeurology700 Children’s DrColumbus, OH 43205 (map)
Learn more about John R. Mytinger
Biography
John R. Mytinger, MD, is an attending child neurologist at Nationwide Children’s and Assistant Professor of Clinical Pediatrics and Neurology at The Ohio State University College of Medicine. He completed his pediatric and child neurology residencies as well as his clinical neurophysiology and epilepsy fellowships at the University of Virginia. He has a special interest in infantile spasms and epileptic encephalopathy.
“My mission is to improve your child’s quality of life and to bring hope and joy to your family. I will treat your child as if they were one of my own children.”
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Dublin Close To Home Center at 5665 Venture Drive
Academic and Clinical Areas
Neurology
Physician Team
Neurology Residency
Faculty
Clinical Neurophysiology Fellowship
Faculty
Primary Department
Pediatrics
Primary Section
Neurology
Awards, Honors & Organizations
Department of Pediatrics William Osler Award, Nationwide Children’s Hospital, 2020 Infantile Spasms Heroes Award, On behalf of the Child Neurology Foundation Board of Directors, presented at the 2015 Annual Meeting of the Child Neurology Society, 2015 Listed, Best Doctors in America
Research
Dr. Mytinger is a clinical research scientist with a special interest in children with developmental and epileptic encephalopathy including but not limited to West syndrome. His publications have focused on the use of first-line (standard) therapies for infantile spasms and the use of clinical EEG to monitor treatment response. He and his team have also developed a reliable method of determining the presence or absence of epileptic encephalopathy using electroencephalography. Publications
Mytinger JR, Parker W, Rust SW, Ahrens SM, Albert DV, Beatty CW, Chrisman J, Clark DJ, Debs A, Denney D, Karn M, Herbst J, Ostendorf AP, Taylor MC, Twanow J, Vidaurre J, Patel AD. Prioritizing Hormone Therapy Over Vigabatrin as the First Treatment for Infantile Spasms: A Quality Improvement Initiative. Neurology. 2022 Aug 29;
Yuskaitis CJ, Mytinger JR, Baumer FM, Zhang B, Liu S, Samanta D, Hussain SA, Yozawitz EG, Keator CG, Joshi C, Singh RK, Bhatia S, Bhalla S, Shellhaas R, Harini C, Pediatric Epilepsy Research Consortium.. Association of Time to Clinical Remission With Sustained Resolution in Children With New-Onset Infantile Spasms. Neurology. 2022 Aug 29;
Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium., National Infantile Spasms Consortium.. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 Apr 7;
Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 Jan 19; 8830738211073400.
Romero Milà B, Remakanthakurup Sindhu K, Mytinger JR, Shrey DW, Lopour BA. EEG biomarkers for the diagnosis and treatment of infantile spasms. Front Neurol. 2022; 13: 960454.
Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Jul 15;
Mytinger JR. Definitions and Diagnostic Criteria for Infantile Spasms and West Syndrome - Historical Perspectives and Practical Considerations. Semin Pediatr Neurol. 2021 Jul; 38: 100893.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF. A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score. Epilepsy Res. 2021 Jul; 173: 106631.
Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 Nov; 35: 924-933.
Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 Oct; 35: 828-834.
Mytinger JR. High-Dose Prednisolone as a First-line Treatment for Infantile Spasms. Pediatr Neurol. 2018 Oct; 87: 3-4.
Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 Apr 1; 172: 352-360.
Mytinger JR, Weber A, Vidaurre J. High Amplitude Background Slow Waves in Normal Children Aged 3 to 18 Months: Implications for the Consideration of Hypsarhythmia. J Clin Neurophysiol. 2018 Mar; 35: 151-154.
Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13: e0193599.
Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75: 73-79.
Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 Sep 1; 171: 863-871.
View More Publications
Education
Date of Appointment at Nationwide Children’s Hospital: 07/01/2012
Board Certifications
Child Neurology Clinical Neurophysiology Epilepsy Neurology
Fellowship
University of Virginia Health Systems
Date Completed: 06/30/2011
Residency
University of Virginia Health Systems
Date Completed: 06/30/2010
Residency
University of Virginia Health Systems
Date Completed: 06/30/2007
Medical School
Albany Medical College
Date Completed: 05/26/2005
Contact Information
Pediatrics
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
Neurology700 Children's DrColumbus, OH 43205 (map)
Contact Information
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
PediatricsNeurology700 Children’s DrColumbus, OH 43205 (map)
Learn more about John R. Mytinger
Biography
John R. Mytinger, MD, is an attending child neurologist at Nationwide Children’s and Assistant Professor of Clinical Pediatrics and Neurology at The Ohio State University College of Medicine. He completed his pediatric and child neurology residencies as well as his clinical neurophysiology and epilepsy fellowships at the University of Virginia. He has a special interest in infantile spasms and epileptic encephalopathy.
“My mission is to improve your child’s quality of life and to bring hope and joy to your family. I will treat your child as if they were one of my own children.”
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Dublin Close To Home Center at 5665 Venture Drive
Academic and Clinical Areas
Neurology
Physician Team
Neurology Residency
Faculty
Clinical Neurophysiology Fellowship
Faculty
Primary Department
Pediatrics
Primary Section
Neurology
Awards, Honors & Organizations
Department of Pediatrics William Osler Award, Nationwide Children’s Hospital, 2020 Infantile Spasms Heroes Award, On behalf of the Child Neurology Foundation Board of Directors, presented at the 2015 Annual Meeting of the Child Neurology Society, 2015 Listed, Best Doctors in America
Research
Dr. Mytinger is a clinical research scientist with a special interest in children with developmental and epileptic encephalopathy including but not limited to West syndrome. His publications have focused on the use of first-line (standard) therapies for infantile spasms and the use of clinical EEG to monitor treatment response. He and his team have also developed a reliable method of determining the presence or absence of epileptic encephalopathy using electroencephalography. Publications
Mytinger JR, Parker W, Rust SW, Ahrens SM, Albert DV, Beatty CW, Chrisman J, Clark DJ, Debs A, Denney D, Karn M, Herbst J, Ostendorf AP, Taylor MC, Twanow J, Vidaurre J, Patel AD. Prioritizing Hormone Therapy Over Vigabatrin as the First Treatment for Infantile Spasms: A Quality Improvement Initiative. Neurology. 2022 Aug 29;
Yuskaitis CJ, Mytinger JR, Baumer FM, Zhang B, Liu S, Samanta D, Hussain SA, Yozawitz EG, Keator CG, Joshi C, Singh RK, Bhatia S, Bhalla S, Shellhaas R, Harini C, Pediatric Epilepsy Research Consortium.. Association of Time to Clinical Remission With Sustained Resolution in Children With New-Onset Infantile Spasms. Neurology. 2022 Aug 29;
Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium., National Infantile Spasms Consortium.. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 Apr 7;
Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 Jan 19; 8830738211073400.
Romero Milà B, Remakanthakurup Sindhu K, Mytinger JR, Shrey DW, Lopour BA. EEG biomarkers for the diagnosis and treatment of infantile spasms. Front Neurol. 2022; 13: 960454.
Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Jul 15;
Mytinger JR. Definitions and Diagnostic Criteria for Infantile Spasms and West Syndrome - Historical Perspectives and Practical Considerations. Semin Pediatr Neurol. 2021 Jul; 38: 100893.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF. A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score. Epilepsy Res. 2021 Jul; 173: 106631.
Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 Nov; 35: 924-933.
Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 Oct; 35: 828-834.
Mytinger JR. High-Dose Prednisolone as a First-line Treatment for Infantile Spasms. Pediatr Neurol. 2018 Oct; 87: 3-4.
Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 Apr 1; 172: 352-360.
Mytinger JR, Weber A, Vidaurre J. High Amplitude Background Slow Waves in Normal Children Aged 3 to 18 Months: Implications for the Consideration of Hypsarhythmia. J Clin Neurophysiol. 2018 Mar; 35: 151-154.
Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13: e0193599.
Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75: 73-79.
Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 Sep 1; 171: 863-871.
View More Publications
Education
Date of Appointment at Nationwide Children’s Hospital: 07/01/2012
Board Certifications
Child Neurology Clinical Neurophysiology Epilepsy Neurology
Fellowship
University of Virginia Health Systems
Date Completed: 06/30/2011
Residency
University of Virginia Health Systems
Date Completed: 06/30/2010
Residency
University of Virginia Health Systems
Date Completed: 06/30/2007
Medical School
Albany Medical College
Date Completed: 05/26/2005
Contact Information
Pediatrics
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
Neurology700 Children's DrColumbus, OH 43205 (map)
Contact Information
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
PediatricsNeurology700 Children’s DrColumbus, OH 43205 (map)
Learn more about John R. Mytinger
Contact Information
- Call us at:
- (614) 722-4625
- Fax us at:
- (614) 722-4633
- PediatricsNeurology700 Children’s DrColumbus, OH 43205 (map)
Learn more about John R. Mytinger
Biography
John R. Mytinger, MD, is an attending child neurologist at Nationwide Children’s and Assistant Professor of Clinical Pediatrics and Neurology at The Ohio State University College of Medicine. He completed his pediatric and child neurology residencies as well as his clinical neurophysiology and epilepsy fellowships at the University of Virginia. He has a special interest in infantile spasms and epileptic encephalopathy.
Biography
John R. Mytinger, MD, is an attending child neurologist at Nationwide Children’s and Assistant Professor of Clinical Pediatrics and Neurology at The Ohio State University College of Medicine. He completed his pediatric and child neurology residencies as well as his clinical neurophysiology and epilepsy fellowships at the University of Virginia. He has a special interest in infantile spasms and epileptic encephalopathy.
Biography
John R. Mytinger, MD, is an attending child neurologist at Nationwide Children’s and Assistant Professor of Clinical Pediatrics and Neurology at The Ohio State University College of Medicine. He completed his pediatric and child neurology residencies as well as his clinical neurophysiology and epilepsy fellowships at the University of Virginia. He has a special interest in infantile spasms and epileptic encephalopathy.
John R. Mytinger, MD, is an attending child neurologist at Nationwide Children’s and Assistant Professor of Clinical Pediatrics and Neurology at The Ohio State University College of Medicine. He completed his pediatric and child neurology residencies as well as his clinical neurophysiology and epilepsy fellowships at the University of Virginia. He has a special interest in infantile spasms and epileptic encephalopathy.
John R. Mytinger, MD, is an attending child neurologist at Nationwide Children’s and Assistant Professor of Clinical Pediatrics and Neurology at The Ohio State University College of Medicine. He completed his pediatric and child neurology residencies as well as his clinical neurophysiology and epilepsy fellowships at the University of Virginia. He has a special interest in infantile spasms and epileptic encephalopathy.
“My mission is to improve your child’s quality of life and to bring hope and joy to your family. I will treat your child as if they were one of my own children.”
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Dublin Close To Home Center at 5665 Venture Drive
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Dublin Close To Home Center at 5665 Venture Drive
Patient Care
Locations
Main Campus of Nationwide Children’s Hospital
Dublin Close To Home Center at 5665 Venture Drive
Locations
Main Campus of Nationwide Children’s Hospital
Dublin Close To Home Center at 5665 Venture Drive
Locations
Main Campus of Nationwide Children’s Hospital
Dublin Close To Home Center at 5665 Venture Drive
Locations
Main Campus of Nationwide Children’s Hospital
Dublin Close To Home Center at 5665 Venture Drive
- Main Campus of Nationwide Children’s Hospital
- Dublin Close To Home Center at 5665 Venture Drive
Academic and Clinical Areas
Neurology
Physician Team
Neurology Residency
Faculty
Clinical Neurophysiology Fellowship
Faculty
Primary Department
Pediatrics
Primary Section
Neurology
Academic and Clinical Areas
Neurology
Physician Team
Neurology Residency
Faculty
Clinical Neurophysiology Fellowship
Faculty
Primary Department
Pediatrics
Primary Section
Neurology
Academic and Clinical Areas
Neurology
Physician Team
Neurology Residency
Faculty
Clinical Neurophysiology Fellowship
Faculty
Primary Department
Pediatrics
Primary Section
Neurology
Neurology
Physician Team
Neurology Residency
Faculty
Clinical Neurophysiology Fellowship
Faculty
Primary Department
Pediatrics
Primary Section
Neurology
- Neurology
- Physician Team
- Neurology Residency
- Faculty
- Clinical Neurophysiology Fellowship
- Faculty
- Primary Department
- Pediatrics
- Primary Section
- Neurology
Awards, Honors & Organizations
Department of Pediatrics William Osler Award, Nationwide Children’s Hospital, 2020 Infantile Spasms Heroes Award, On behalf of the Child Neurology Foundation Board of Directors, presented at the 2015 Annual Meeting of the Child Neurology Society, 2015 Listed, Best Doctors in America
Awards, Honors & Organizations
Department of Pediatrics William Osler Award, Nationwide Children’s Hospital, 2020 Infantile Spasms Heroes Award, On behalf of the Child Neurology Foundation Board of Directors, presented at the 2015 Annual Meeting of the Child Neurology Society, 2015 Listed, Best Doctors in America
Awards, Honors & Organizations
Department of Pediatrics William Osler Award, Nationwide Children’s Hospital, 2020 Infantile Spasms Heroes Award, On behalf of the Child Neurology Foundation Board of Directors, presented at the 2015 Annual Meeting of the Child Neurology Society, 2015 Listed, Best Doctors in America
Department of Pediatrics William Osler Award, Nationwide Children’s Hospital, 2020 Infantile Spasms Heroes Award, On behalf of the Child Neurology Foundation Board of Directors, presented at the 2015 Annual Meeting of the Child Neurology Society, 2015 Listed, Best Doctors in America
- Department of Pediatrics William Osler Award, Nationwide Children’s Hospital, 2020
- Infantile Spasms Heroes Award, On behalf of the Child Neurology Foundation Board of Directors, presented at the 2015 Annual Meeting of the Child Neurology Society, 2015
- Listed, Best Doctors in America
Research
Dr. Mytinger is a clinical research scientist with a special interest in children with developmental and epileptic encephalopathy including but not limited to West syndrome. His publications have focused on the use of first-line (standard) therapies for infantile spasms and the use of clinical EEG to monitor treatment response. He and his team have also developed a reliable method of determining the presence or absence of epileptic encephalopathy using electroencephalography. Publications
Mytinger JR, Parker W, Rust SW, Ahrens SM, Albert DV, Beatty CW, Chrisman J, Clark DJ, Debs A, Denney D, Karn M, Herbst J, Ostendorf AP, Taylor MC, Twanow J, Vidaurre J, Patel AD. Prioritizing Hormone Therapy Over Vigabatrin as the First Treatment for Infantile Spasms: A Quality Improvement Initiative. Neurology. 2022 Aug 29;
Yuskaitis CJ, Mytinger JR, Baumer FM, Zhang B, Liu S, Samanta D, Hussain SA, Yozawitz EG, Keator CG, Joshi C, Singh RK, Bhatia S, Bhalla S, Shellhaas R, Harini C, Pediatric Epilepsy Research Consortium.. Association of Time to Clinical Remission With Sustained Resolution in Children With New-Onset Infantile Spasms. Neurology. 2022 Aug 29;
Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium., National Infantile Spasms Consortium.. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 Apr 7;
Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 Jan 19; 8830738211073400.
Romero Milà B, Remakanthakurup Sindhu K, Mytinger JR, Shrey DW, Lopour BA. EEG biomarkers for the diagnosis and treatment of infantile spasms. Front Neurol. 2022; 13: 960454.
Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Jul 15;
Mytinger JR. Definitions and Diagnostic Criteria for Infantile Spasms and West Syndrome - Historical Perspectives and Practical Considerations. Semin Pediatr Neurol. 2021 Jul; 38: 100893.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF. A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score. Epilepsy Res. 2021 Jul; 173: 106631.
Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 Nov; 35: 924-933.
Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 Oct; 35: 828-834.
Mytinger JR. High-Dose Prednisolone as a First-line Treatment for Infantile Spasms. Pediatr Neurol. 2018 Oct; 87: 3-4.
Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 Apr 1; 172: 352-360.
Mytinger JR, Weber A, Vidaurre J. High Amplitude Background Slow Waves in Normal Children Aged 3 to 18 Months: Implications for the Consideration of Hypsarhythmia. J Clin Neurophysiol. 2018 Mar; 35: 151-154.
Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13: e0193599.
Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75: 73-79.
Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 Sep 1; 171: 863-871.
View More Publications
Research
Dr. Mytinger is a clinical research scientist with a special interest in children with developmental and epileptic encephalopathy including but not limited to West syndrome. His publications have focused on the use of first-line (standard) therapies for infantile spasms and the use of clinical EEG to monitor treatment response. He and his team have also developed a reliable method of determining the presence or absence of epileptic encephalopathy using electroencephalography. Publications
Mytinger JR, Parker W, Rust SW, Ahrens SM, Albert DV, Beatty CW, Chrisman J, Clark DJ, Debs A, Denney D, Karn M, Herbst J, Ostendorf AP, Taylor MC, Twanow J, Vidaurre J, Patel AD. Prioritizing Hormone Therapy Over Vigabatrin as the First Treatment for Infantile Spasms: A Quality Improvement Initiative. Neurology. 2022 Aug 29;
Yuskaitis CJ, Mytinger JR, Baumer FM, Zhang B, Liu S, Samanta D, Hussain SA, Yozawitz EG, Keator CG, Joshi C, Singh RK, Bhatia S, Bhalla S, Shellhaas R, Harini C, Pediatric Epilepsy Research Consortium.. Association of Time to Clinical Remission With Sustained Resolution in Children With New-Onset Infantile Spasms. Neurology. 2022 Aug 29;
Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium., National Infantile Spasms Consortium.. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 Apr 7;
Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 Jan 19; 8830738211073400.
Romero Milà B, Remakanthakurup Sindhu K, Mytinger JR, Shrey DW, Lopour BA. EEG biomarkers for the diagnosis and treatment of infantile spasms. Front Neurol. 2022; 13: 960454.
Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Jul 15;
Mytinger JR. Definitions and Diagnostic Criteria for Infantile Spasms and West Syndrome - Historical Perspectives and Practical Considerations. Semin Pediatr Neurol. 2021 Jul; 38: 100893.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF. A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score. Epilepsy Res. 2021 Jul; 173: 106631.
Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 Nov; 35: 924-933.
Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 Oct; 35: 828-834.
Mytinger JR. High-Dose Prednisolone as a First-line Treatment for Infantile Spasms. Pediatr Neurol. 2018 Oct; 87: 3-4.
Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 Apr 1; 172: 352-360.
Mytinger JR, Weber A, Vidaurre J. High Amplitude Background Slow Waves in Normal Children Aged 3 to 18 Months: Implications for the Consideration of Hypsarhythmia. J Clin Neurophysiol. 2018 Mar; 35: 151-154.
Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13: e0193599.
Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75: 73-79.
Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 Sep 1; 171: 863-871.
View More Publications
Research
Dr. Mytinger is a clinical research scientist with a special interest in children with developmental and epileptic encephalopathy including but not limited to West syndrome. His publications have focused on the use of first-line (standard) therapies for infantile spasms and the use of clinical EEG to monitor treatment response. He and his team have also developed a reliable method of determining the presence or absence of epileptic encephalopathy using electroencephalography. Publications
Mytinger JR, Parker W, Rust SW, Ahrens SM, Albert DV, Beatty CW, Chrisman J, Clark DJ, Debs A, Denney D, Karn M, Herbst J, Ostendorf AP, Taylor MC, Twanow J, Vidaurre J, Patel AD. Prioritizing Hormone Therapy Over Vigabatrin as the First Treatment for Infantile Spasms: A Quality Improvement Initiative. Neurology. 2022 Aug 29;
Yuskaitis CJ, Mytinger JR, Baumer FM, Zhang B, Liu S, Samanta D, Hussain SA, Yozawitz EG, Keator CG, Joshi C, Singh RK, Bhatia S, Bhalla S, Shellhaas R, Harini C, Pediatric Epilepsy Research Consortium.. Association of Time to Clinical Remission With Sustained Resolution in Children With New-Onset Infantile Spasms. Neurology. 2022 Aug 29;
Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium., National Infantile Spasms Consortium.. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 Apr 7;
Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 Jan 19; 8830738211073400.
Romero Milà B, Remakanthakurup Sindhu K, Mytinger JR, Shrey DW, Lopour BA. EEG biomarkers for the diagnosis and treatment of infantile spasms. Front Neurol. 2022; 13: 960454.
Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Jul 15;
Mytinger JR. Definitions and Diagnostic Criteria for Infantile Spasms and West Syndrome - Historical Perspectives and Practical Considerations. Semin Pediatr Neurol. 2021 Jul; 38: 100893.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF. A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score. Epilepsy Res. 2021 Jul; 173: 106631.
Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 Nov; 35: 924-933.
Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 Oct; 35: 828-834.
Mytinger JR. High-Dose Prednisolone as a First-line Treatment for Infantile Spasms. Pediatr Neurol. 2018 Oct; 87: 3-4.
Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 Apr 1; 172: 352-360.
Mytinger JR, Weber A, Vidaurre J. High Amplitude Background Slow Waves in Normal Children Aged 3 to 18 Months: Implications for the Consideration of Hypsarhythmia. J Clin Neurophysiol. 2018 Mar; 35: 151-154.
Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13: e0193599.
Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75: 73-79.
Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 Sep 1; 171: 863-871.
View More Publications
Dr. Mytinger is a clinical research scientist with a special interest in children with developmental and epileptic encephalopathy including but not limited to West syndrome. His publications have focused on the use of first-line (standard) therapies for infantile spasms and the use of clinical EEG to monitor treatment response. He and his team have also developed a reliable method of determining the presence or absence of epileptic encephalopathy using electroencephalography. Publications
Mytinger JR, Parker W, Rust SW, Ahrens SM, Albert DV, Beatty CW, Chrisman J, Clark DJ, Debs A, Denney D, Karn M, Herbst J, Ostendorf AP, Taylor MC, Twanow J, Vidaurre J, Patel AD. Prioritizing Hormone Therapy Over Vigabatrin as the First Treatment for Infantile Spasms: A Quality Improvement Initiative. Neurology. 2022 Aug 29;
Yuskaitis CJ, Mytinger JR, Baumer FM, Zhang B, Liu S, Samanta D, Hussain SA, Yozawitz EG, Keator CG, Joshi C, Singh RK, Bhatia S, Bhalla S, Shellhaas R, Harini C, Pediatric Epilepsy Research Consortium.. Association of Time to Clinical Remission With Sustained Resolution in Children With New-Onset Infantile Spasms. Neurology. 2022 Aug 29;
Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium., National Infantile Spasms Consortium.. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 Apr 7;
Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 Jan 19; 8830738211073400.
Romero Milà B, Remakanthakurup Sindhu K, Mytinger JR, Shrey DW, Lopour BA. EEG biomarkers for the diagnosis and treatment of infantile spasms. Front Neurol. 2022; 13: 960454.
Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Jul 15;
Mytinger JR. Definitions and Diagnostic Criteria for Infantile Spasms and West Syndrome - Historical Perspectives and Practical Considerations. Semin Pediatr Neurol. 2021 Jul; 38: 100893.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF. A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score. Epilepsy Res. 2021 Jul; 173: 106631.
Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 Nov; 35: 924-933.
Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 Oct; 35: 828-834.
Mytinger JR. High-Dose Prednisolone as a First-line Treatment for Infantile Spasms. Pediatr Neurol. 2018 Oct; 87: 3-4.
Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 Apr 1; 172: 352-360.
Mytinger JR, Weber A, Vidaurre J. High Amplitude Background Slow Waves in Normal Children Aged 3 to 18 Months: Implications for the Consideration of Hypsarhythmia. J Clin Neurophysiol. 2018 Mar; 35: 151-154.
Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13: e0193599.
Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75: 73-79.
Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 Sep 1; 171: 863-871.
View More Publications
Dr. Mytinger is a clinical research scientist with a special interest in children with developmental and epileptic encephalopathy including but not limited to West syndrome. His publications have focused on the use of first-line (standard) therapies for infantile spasms and the use of clinical EEG to monitor treatment response. He and his team have also developed a reliable method of determining the presence or absence of epileptic encephalopathy using electroencephalography.
Mytinger JR, Parker W, Rust SW, Ahrens SM, Albert DV, Beatty CW, Chrisman J, Clark DJ, Debs A, Denney D, Karn M, Herbst J, Ostendorf AP, Taylor MC, Twanow J, Vidaurre J, Patel AD. Prioritizing Hormone Therapy Over Vigabatrin as the First Treatment for Infantile Spasms: A Quality Improvement Initiative. Neurology. 2022 Aug 29;
Yuskaitis CJ, Mytinger JR, Baumer FM, Zhang B, Liu S, Samanta D, Hussain SA, Yozawitz EG, Keator CG, Joshi C, Singh RK, Bhatia S, Bhalla S, Shellhaas R, Harini C, Pediatric Epilepsy Research Consortium.. Association of Time to Clinical Remission With Sustained Resolution in Children With New-Onset Infantile Spasms. Neurology. 2022 Aug 29;
Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium., National Infantile Spasms Consortium.. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 Apr 7;
Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 Jan 19; 8830738211073400.
Romero Milà B, Remakanthakurup Sindhu K, Mytinger JR, Shrey DW, Lopour BA. EEG biomarkers for the diagnosis and treatment of infantile spasms. Front Neurol. 2022; 13: 960454.
Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Jul 15;
Mytinger JR. Definitions and Diagnostic Criteria for Infantile Spasms and West Syndrome - Historical Perspectives and Practical Considerations. Semin Pediatr Neurol. 2021 Jul; 38: 100893.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF. A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score. Epilepsy Res. 2021 Jul; 173: 106631.
Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 Nov; 35: 924-933.
Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 Oct; 35: 828-834.
Mytinger JR. High-Dose Prednisolone as a First-line Treatment for Infantile Spasms. Pediatr Neurol. 2018 Oct; 87: 3-4.
Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 Apr 1; 172: 352-360.
Mytinger JR, Weber A, Vidaurre J. High Amplitude Background Slow Waves in Normal Children Aged 3 to 18 Months: Implications for the Consideration of Hypsarhythmia. J Clin Neurophysiol. 2018 Mar; 35: 151-154.
Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13: e0193599.
Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75: 73-79.
Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 Sep 1; 171: 863-871.
View More Publications
- Mytinger JR, Parker W, Rust SW, Ahrens SM, Albert DV, Beatty CW, Chrisman J, Clark DJ, Debs A, Denney D, Karn M, Herbst J, Ostendorf AP, Taylor MC, Twanow J, Vidaurre J, Patel AD. Prioritizing Hormone Therapy Over Vigabatrin as the First Treatment for Infantile Spasms: A Quality Improvement Initiative. Neurology. 2022 Aug 29;
- Yuskaitis CJ, Mytinger JR, Baumer FM, Zhang B, Liu S, Samanta D, Hussain SA, Yozawitz EG, Keator CG, Joshi C, Singh RK, Bhatia S, Bhalla S, Shellhaas R, Harini C, Pediatric Epilepsy Research Consortium.. Association of Time to Clinical Remission With Sustained Resolution in Children With New-Onset Infantile Spasms. Neurology. 2022 Aug 29;
- Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium., National Infantile Spasms Consortium.. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 Apr 7;
- Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 Jan 19; 8830738211073400.
- Romero Milà B, Remakanthakurup Sindhu K, Mytinger JR, Shrey DW, Lopour BA. EEG biomarkers for the diagnosis and treatment of infantile spasms. Front Neurol. 2022; 13: 960454.
- Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Jul 15;
- Mytinger JR. Definitions and Diagnostic Criteria for Infantile Spasms and West Syndrome - Historical Perspectives and Practical Considerations. Semin Pediatr Neurol. 2021 Jul; 38: 100893.
- Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF. A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score. Epilepsy Res. 2021 Jul; 173: 106631.
- Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 Nov; 35: 924-933.
- Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 Oct; 35: 828-834.
- Mytinger JR. High-Dose Prednisolone as a First-line Treatment for Infantile Spasms. Pediatr Neurol. 2018 Oct; 87: 3-4.
- Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 Apr 1; 172: 352-360.
- Mytinger JR, Weber A, Vidaurre J. High Amplitude Background Slow Waves in Normal Children Aged 3 to 18 Months: Implications for the Consideration of Hypsarhythmia. J Clin Neurophysiol. 2018 Mar; 35: 151-154.
- Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13: e0193599.
- Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75: 73-79.
- Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 Sep 1; 171: 863-871.
Education
Date of Appointment at Nationwide Children’s Hospital: 07/01/2012
Board Certifications
Child Neurology Clinical Neurophysiology Epilepsy Neurology
Fellowship
University of Virginia Health Systems
Date Completed: 06/30/2011
Residency
University of Virginia Health Systems
Date Completed: 06/30/2010
Residency
University of Virginia Health Systems
Date Completed: 06/30/2007
Medical School
Albany Medical College
Date Completed: 05/26/2005
Education
Date of Appointment at Nationwide Children’s Hospital: 07/01/2012
Board Certifications
Child Neurology Clinical Neurophysiology Epilepsy Neurology
Fellowship
University of Virginia Health Systems
Date Completed: 06/30/2011
Residency
University of Virginia Health Systems
Date Completed: 06/30/2010
Residency
University of Virginia Health Systems
Date Completed: 06/30/2007
Medical School
Albany Medical College
Date Completed: 05/26/2005
Education
Date of Appointment at Nationwide Children’s Hospital: 07/01/2012
Board Certifications
Child Neurology Clinical Neurophysiology Epilepsy Neurology
Fellowship
University of Virginia Health Systems
Date Completed: 06/30/2011
Residency
University of Virginia Health Systems
Date Completed: 06/30/2010
Residency
University of Virginia Health Systems
Date Completed: 06/30/2007
Medical School
Albany Medical College
Date Completed: 05/26/2005
Date of Appointment at Nationwide Children’s Hospital: 07/01/2012
Board Certifications
Child Neurology Clinical Neurophysiology Epilepsy Neurology
Fellowship
University of Virginia Health Systems
Date Completed: 06/30/2011
Residency
University of Virginia Health Systems
Date Completed: 06/30/2010
Residency
University of Virginia Health Systems
Date Completed: 06/30/2007
Medical School
Albany Medical College
Date Completed: 05/26/2005
Date of Appointment at Nationwide Children’s Hospital: 07/01/2012
Board Certifications
Child Neurology Clinical Neurophysiology Epilepsy Neurology
Fellowship
University of Virginia Health Systems
Date Completed: 06/30/2011
Residency
University of Virginia Health Systems
Date Completed: 06/30/2010
Residency
University of Virginia Health Systems
Date Completed: 06/30/2007
Medical School
Albany Medical College
Date Completed: 05/26/2005
- Child Neurology
- Clinical Neurophysiology
- Epilepsy
- Neurology
Contact Information
Pediatrics
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
Neurology700 Children's DrColumbus, OH 43205 (map)
Contact Information
Pediatrics
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
Neurology700 Children's DrColumbus, OH 43205 (map)
Contact Information
Pediatrics
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
Neurology700 Children's DrColumbus, OH 43205 (map)
Pediatrics
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
Neurology700 Children's DrColumbus, OH 43205 (map)
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
Neurology700 Children's DrColumbus, OH 43205 (map)
Call us at: (614) 722-4625
Fax us at: (614) 722-4633
Neurology700 Children's DrColumbus, OH 43205 (map)
- Call us at:
- (614) 722-4625
- Fax us at:
- (614) 722-4633
- Neurology700 Children’s DrColumbus, OH 43205 (map)
