Diana Zepeda Orozco

Contact Information

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

PediatricsNephrology700 Children’s DrColumbus, OH 43205 (map)

Learn more about Diana Zepeda-Orozco

Biography

Diana Zepeda-Orozco, MD, is the Co-Director of the Acute Kidney Injury program at Nationwide Children’s Hospital, a Principal Investigator in the Kidney and Urinary Tract Research Center within The Abigail Wexner Research Institute at Nationwide Children’s Hospital, an Attending Physician for the Division of Pediatric Nephrology and Hypertension, and an assistant professor of pediatrics at The Ohio State University College of Medicine. Dr. Zepeda-Orozco earned her medical degree at the University of Guadalajara, Mexico. She performed her Pediatrics training at LeBonheur Children’s Hospital, and her Pediatric Nephrology and Renal Transplant Fellowships at UT Southwestern Medical Center Dallas. After completion of her fellowships, she was recruited to the University of Iowa as Director of the Pediatric Kidney Transplant program. During that time, she did her Master of Science in Translational Biomedicine. Dr. Zepeda-Orozco joined Nationwide Children’s hospital in 2020. Her laboratory studies mitochondrial contributions to kidney injury. With her training, Dr. Zepeda-Orozco is interested in developing novel mitochondrial therapeutic approaches to prevent and treat kidney injury with deep understanding of the pathophysiology using murine pre-clinical models of kidney injury. As a physician scientist, she is devoted to the development of novel diagnostic approaches that will facilitate targeted treatment for kidney injury using clinical samples. Outside work, Dr. Zepeda-Orozco enjoys outdoor activities with her family, cooking and eating different types of foods, and reading a good book.

Academic and Clinical Areas

Nephrology and Hypertension

Physician Team

Primary Department

Pediatrics

Primary Section

Nephrology and Hypertension

Research

Publications

                  Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29; 11: 

                


                  Mapuskar KA, Steinbach EJ, Zaher A, Riley DP, Beardsley RA, Keene JL, Holmlund JT, Anderson CM, Zepeda-Orozco D, Buatti JM, Spitz DR, Allen BG. Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury. Antioxidants (Basel). 2021 Aug 24; 10: 

                


                  Petronek MS, Steinbach EJ, Kalen AL, Builta ZJ, Callaghan CM, Hyer DE, Spitz DR, Flynn RT, Buatti JM, Magnotta VA, Zepeda-Orozco D, St-Aubin JJ, Allen BG. Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model. Radiat Res. 2021 Mar 1; 195: 230-234.

                


                  Perrenoud L, Kruse NT, Andrews E, You Z, Chonchol M, Wu C, Ten Eyck P, Zepeda-Orozco D, Jalal D. Uric Acid Lowering and Biomarkers of Kidney Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney Med. 2020 Mar-Apr; 2: 155-161.

                


                  Jin H, Zhang Y, Ding Q, Wang SS, Rastogi P, Dai DF, Lu D, Purvis M, Cao C, Wang A, Liu D, Ren C, Elhadi S, Hu MC, Chai Y, Zepeda-Orozco D, Campisi J, Attanasio M. Epithelial innate immunity mediates tubular cell senescence after kidney injury. JCI Insight. 2019 Jan 24; 4: 

                


                  Mapuskar KA, Wen H, Holanda DG, Rastogi P, Steinbach E, Han R, Coleman MC, Attanasio M, Riley DP, Spitz DR, Allen BG, Zepeda-Orozco D. Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease. Redox Biol. 2019 Jan; 20: 98-106.

                


                  Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017 Sep; 5: 

View More Publications

Education

Date of Appointment at Nationwide Children’s Hospital: 02/28/2020

Board Certifications

Pediatric Nephrology Pediatrics

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 06/30/2012

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 07/30/2011

Residency

Le Bonheur Children’s Hospital

Date Completed: 06/30/2008

Medical School

University of Guadalajara

Date Completed: 08/01/2004

Contact Information

Pediatrics

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

                    Nephrology700 Children's DrColumbus, OH 43205 (map)

Contact Information

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

PediatricsNephrology700 Children’s DrColumbus, OH 43205 (map)

Learn more about Diana Zepeda-Orozco

Biography

Diana Zepeda-Orozco, MD, is the Co-Director of the Acute Kidney Injury program at Nationwide Children’s Hospital, a Principal Investigator in the Kidney and Urinary Tract Research Center within The Abigail Wexner Research Institute at Nationwide Children’s Hospital, an Attending Physician for the Division of Pediatric Nephrology and Hypertension, and an assistant professor of pediatrics at The Ohio State University College of Medicine. Dr. Zepeda-Orozco earned her medical degree at the University of Guadalajara, Mexico. She performed her Pediatrics training at LeBonheur Children’s Hospital, and her Pediatric Nephrology and Renal Transplant Fellowships at UT Southwestern Medical Center Dallas. After completion of her fellowships, she was recruited to the University of Iowa as Director of the Pediatric Kidney Transplant program. During that time, she did her Master of Science in Translational Biomedicine. Dr. Zepeda-Orozco joined Nationwide Children’s hospital in 2020. Her laboratory studies mitochondrial contributions to kidney injury. With her training, Dr. Zepeda-Orozco is interested in developing novel mitochondrial therapeutic approaches to prevent and treat kidney injury with deep understanding of the pathophysiology using murine pre-clinical models of kidney injury. As a physician scientist, she is devoted to the development of novel diagnostic approaches that will facilitate targeted treatment for kidney injury using clinical samples. Outside work, Dr. Zepeda-Orozco enjoys outdoor activities with her family, cooking and eating different types of foods, and reading a good book.

Academic and Clinical Areas

Nephrology and Hypertension

Physician Team

Primary Department

Pediatrics

Primary Section

Nephrology and Hypertension

Research

Publications

                  Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29; 11: 

                


                  Mapuskar KA, Steinbach EJ, Zaher A, Riley DP, Beardsley RA, Keene JL, Holmlund JT, Anderson CM, Zepeda-Orozco D, Buatti JM, Spitz DR, Allen BG. Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury. Antioxidants (Basel). 2021 Aug 24; 10: 

                


                  Petronek MS, Steinbach EJ, Kalen AL, Builta ZJ, Callaghan CM, Hyer DE, Spitz DR, Flynn RT, Buatti JM, Magnotta VA, Zepeda-Orozco D, St-Aubin JJ, Allen BG. Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model. Radiat Res. 2021 Mar 1; 195: 230-234.

                


                  Perrenoud L, Kruse NT, Andrews E, You Z, Chonchol M, Wu C, Ten Eyck P, Zepeda-Orozco D, Jalal D. Uric Acid Lowering and Biomarkers of Kidney Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney Med. 2020 Mar-Apr; 2: 155-161.

                


                  Jin H, Zhang Y, Ding Q, Wang SS, Rastogi P, Dai DF, Lu D, Purvis M, Cao C, Wang A, Liu D, Ren C, Elhadi S, Hu MC, Chai Y, Zepeda-Orozco D, Campisi J, Attanasio M. Epithelial innate immunity mediates tubular cell senescence after kidney injury. JCI Insight. 2019 Jan 24; 4: 

                


                  Mapuskar KA, Wen H, Holanda DG, Rastogi P, Steinbach E, Han R, Coleman MC, Attanasio M, Riley DP, Spitz DR, Allen BG, Zepeda-Orozco D. Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease. Redox Biol. 2019 Jan; 20: 98-106.

                


                  Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017 Sep; 5: 

View More Publications

Education

Date of Appointment at Nationwide Children’s Hospital: 02/28/2020

Board Certifications

Pediatric Nephrology Pediatrics

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 06/30/2012

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 07/30/2011

Residency

Le Bonheur Children’s Hospital

Date Completed: 06/30/2008

Medical School

University of Guadalajara

Date Completed: 08/01/2004

Contact Information

Pediatrics

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

                    Nephrology700 Children's DrColumbus, OH 43205 (map)

Contact Information

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

PediatricsNephrology700 Children’s DrColumbus, OH 43205 (map)

Learn more about Diana Zepeda-Orozco

Contact Information

• Call us at:
• (614) 722-4360
• Fax us at:
• (614) 722-6482
• PediatricsNephrology700 Children’s DrColumbus, OH 43205 (map)

Learn more about Diana Zepeda-Orozco

Biography

Diana Zepeda-Orozco, MD, is the Co-Director of the Acute Kidney Injury program at Nationwide Children’s Hospital, a Principal Investigator in the Kidney and Urinary Tract Research Center within The Abigail Wexner Research Institute at Nationwide Children’s Hospital, an Attending Physician for the Division of Pediatric Nephrology and Hypertension, and an assistant professor of pediatrics at The Ohio State University College of Medicine. Dr. Zepeda-Orozco earned her medical degree at the University of Guadalajara, Mexico. She performed her Pediatrics training at LeBonheur Children’s Hospital, and her Pediatric Nephrology and Renal Transplant Fellowships at UT Southwestern Medical Center Dallas. After completion of her fellowships, she was recruited to the University of Iowa as Director of the Pediatric Kidney Transplant program. During that time, she did her Master of Science in Translational Biomedicine. Dr. Zepeda-Orozco joined Nationwide Children’s hospital in 2020. Her laboratory studies mitochondrial contributions to kidney injury. With her training, Dr. Zepeda-Orozco is interested in developing novel mitochondrial therapeutic approaches to prevent and treat kidney injury with deep understanding of the pathophysiology using murine pre-clinical models of kidney injury. As a physician scientist, she is devoted to the development of novel diagnostic approaches that will facilitate targeted treatment for kidney injury using clinical samples. Outside work, Dr. Zepeda-Orozco enjoys outdoor activities with her family, cooking and eating different types of foods, and reading a good book.

Biography

Diana Zepeda-Orozco, MD, is the Co-Director of the Acute Kidney Injury program at Nationwide Children’s Hospital, a Principal Investigator in the Kidney and Urinary Tract Research Center within The Abigail Wexner Research Institute at Nationwide Children’s Hospital, an Attending Physician for the Division of Pediatric Nephrology and Hypertension, and an assistant professor of pediatrics at The Ohio State University College of Medicine. Dr. Zepeda-Orozco earned her medical degree at the University of Guadalajara, Mexico. She performed her Pediatrics training at LeBonheur Children’s Hospital, and her Pediatric Nephrology and Renal Transplant Fellowships at UT Southwestern Medical Center Dallas. After completion of her fellowships, she was recruited to the University of Iowa as Director of the Pediatric Kidney Transplant program. During that time, she did her Master of Science in Translational Biomedicine. Dr. Zepeda-Orozco joined Nationwide Children’s hospital in 2020. Her laboratory studies mitochondrial contributions to kidney injury. With her training, Dr. Zepeda-Orozco is interested in developing novel mitochondrial therapeutic approaches to prevent and treat kidney injury with deep understanding of the pathophysiology using murine pre-clinical models of kidney injury. As a physician scientist, she is devoted to the development of novel diagnostic approaches that will facilitate targeted treatment for kidney injury using clinical samples. Outside work, Dr. Zepeda-Orozco enjoys outdoor activities with her family, cooking and eating different types of foods, and reading a good book.

Biography

Diana Zepeda-Orozco, MD, is the Co-Director of the Acute Kidney Injury program at Nationwide Children’s Hospital, a Principal Investigator in the Kidney and Urinary Tract Research Center within The Abigail Wexner Research Institute at Nationwide Children’s Hospital, an Attending Physician for the Division of Pediatric Nephrology and Hypertension, and an assistant professor of pediatrics at The Ohio State University College of Medicine. Dr. Zepeda-Orozco earned her medical degree at the University of Guadalajara, Mexico. She performed her Pediatrics training at LeBonheur Children’s Hospital, and her Pediatric Nephrology and Renal Transplant Fellowships at UT Southwestern Medical Center Dallas. After completion of her fellowships, she was recruited to the University of Iowa as Director of the Pediatric Kidney Transplant program. During that time, she did her Master of Science in Translational Biomedicine. Dr. Zepeda-Orozco joined Nationwide Children’s hospital in 2020. Her laboratory studies mitochondrial contributions to kidney injury. With her training, Dr. Zepeda-Orozco is interested in developing novel mitochondrial therapeutic approaches to prevent and treat kidney injury with deep understanding of the pathophysiology using murine pre-clinical models of kidney injury. As a physician scientist, she is devoted to the development of novel diagnostic approaches that will facilitate targeted treatment for kidney injury using clinical samples. Outside work, Dr. Zepeda-Orozco enjoys outdoor activities with her family, cooking and eating different types of foods, and reading a good book.

Diana Zepeda-Orozco, MD, is the Co-Director of the Acute Kidney Injury program at Nationwide Children’s Hospital, a Principal Investigator in the Kidney and Urinary Tract Research Center within The Abigail Wexner Research Institute at Nationwide Children’s Hospital, an Attending Physician for the Division of Pediatric Nephrology and Hypertension, and an assistant professor of pediatrics at The Ohio State University College of Medicine. Dr. Zepeda-Orozco earned her medical degree at the University of Guadalajara, Mexico. She performed her Pediatrics training at LeBonheur Children’s Hospital, and her Pediatric Nephrology and Renal Transplant Fellowships at UT Southwestern Medical Center Dallas. After completion of her fellowships, she was recruited to the University of Iowa as Director of the Pediatric Kidney Transplant program. During that time, she did her Master of Science in Translational Biomedicine. Dr. Zepeda-Orozco joined Nationwide Children’s hospital in 2020. Her laboratory studies mitochondrial contributions to kidney injury. With her training, Dr. Zepeda-Orozco is interested in developing novel mitochondrial therapeutic approaches to prevent and treat kidney injury with deep understanding of the pathophysiology using murine pre-clinical models of kidney injury. As a physician scientist, she is devoted to the development of novel diagnostic approaches that will facilitate targeted treatment for kidney injury using clinical samples. Outside work, Dr. Zepeda-Orozco enjoys outdoor activities with her family, cooking and eating different types of foods, and reading a good book.

Diana Zepeda-Orozco, MD, is the Co-Director of the Acute Kidney Injury program at Nationwide Children’s Hospital, a Principal Investigator in the Kidney and Urinary Tract Research Center within The Abigail Wexner Research Institute at Nationwide Children’s Hospital, an Attending Physician for the Division of Pediatric Nephrology and Hypertension, and an assistant professor of pediatrics at The Ohio State University College of Medicine.

Dr. Zepeda-Orozco earned her medical degree at the University of Guadalajara, Mexico. She performed her Pediatrics training at LeBonheur Children’s Hospital, and her Pediatric Nephrology and Renal Transplant Fellowships at UT Southwestern Medical Center Dallas. After completion of her fellowships, she was recruited to the University of Iowa as Director of the Pediatric Kidney Transplant program. During that time, she did her Master of Science in Translational Biomedicine.

Dr. Zepeda-Orozco joined Nationwide Children’s hospital in 2020. Her laboratory studies mitochondrial contributions to kidney injury. With her training, Dr. Zepeda-Orozco is interested in developing novel mitochondrial therapeutic approaches to prevent and treat kidney injury with deep understanding of the pathophysiology using murine pre-clinical models of kidney injury. As a physician scientist, she is devoted to the development of novel diagnostic approaches that will facilitate targeted treatment for kidney injury using clinical samples.

Outside work, Dr. Zepeda-Orozco enjoys outdoor activities with her family, cooking and eating different types of foods, and reading a good book.

Academic and Clinical Areas

Nephrology and Hypertension

Physician Team

Primary Department

Pediatrics

Primary Section

Nephrology and Hypertension

Academic and Clinical Areas

Nephrology and Hypertension

Physician Team

Primary Department

Pediatrics

Primary Section

Nephrology and Hypertension

Academic and Clinical Areas

Nephrology and Hypertension

Physician Team

Primary Department

Pediatrics

Primary Section

Nephrology and Hypertension

Nephrology and Hypertension

Physician Team

Primary Department

Pediatrics

Primary Section

Nephrology and Hypertension

• Nephrology and Hypertension
• Physician Team
• Primary Department
• Pediatrics
• Primary Section
• Nephrology and Hypertension

Research

Publications

                  Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29; 11: 

                


                  Mapuskar KA, Steinbach EJ, Zaher A, Riley DP, Beardsley RA, Keene JL, Holmlund JT, Anderson CM, Zepeda-Orozco D, Buatti JM, Spitz DR, Allen BG. Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury. Antioxidants (Basel). 2021 Aug 24; 10: 

                


                  Petronek MS, Steinbach EJ, Kalen AL, Builta ZJ, Callaghan CM, Hyer DE, Spitz DR, Flynn RT, Buatti JM, Magnotta VA, Zepeda-Orozco D, St-Aubin JJ, Allen BG. Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model. Radiat Res. 2021 Mar 1; 195: 230-234.

                


                  Perrenoud L, Kruse NT, Andrews E, You Z, Chonchol M, Wu C, Ten Eyck P, Zepeda-Orozco D, Jalal D. Uric Acid Lowering and Biomarkers of Kidney Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney Med. 2020 Mar-Apr; 2: 155-161.

                


                  Jin H, Zhang Y, Ding Q, Wang SS, Rastogi P, Dai DF, Lu D, Purvis M, Cao C, Wang A, Liu D, Ren C, Elhadi S, Hu MC, Chai Y, Zepeda-Orozco D, Campisi J, Attanasio M. Epithelial innate immunity mediates tubular cell senescence after kidney injury. JCI Insight. 2019 Jan 24; 4: 

                


                  Mapuskar KA, Wen H, Holanda DG, Rastogi P, Steinbach E, Han R, Coleman MC, Attanasio M, Riley DP, Spitz DR, Allen BG, Zepeda-Orozco D. Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease. Redox Biol. 2019 Jan; 20: 98-106.

                


                  Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017 Sep; 5: 

View More Publications

Research

Publications

                  Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29; 11: 

                


                  Mapuskar KA, Steinbach EJ, Zaher A, Riley DP, Beardsley RA, Keene JL, Holmlund JT, Anderson CM, Zepeda-Orozco D, Buatti JM, Spitz DR, Allen BG. Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury. Antioxidants (Basel). 2021 Aug 24; 10: 

                


                  Petronek MS, Steinbach EJ, Kalen AL, Builta ZJ, Callaghan CM, Hyer DE, Spitz DR, Flynn RT, Buatti JM, Magnotta VA, Zepeda-Orozco D, St-Aubin JJ, Allen BG. Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model. Radiat Res. 2021 Mar 1; 195: 230-234.

                


                  Perrenoud L, Kruse NT, Andrews E, You Z, Chonchol M, Wu C, Ten Eyck P, Zepeda-Orozco D, Jalal D. Uric Acid Lowering and Biomarkers of Kidney Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney Med. 2020 Mar-Apr; 2: 155-161.

                


                  Jin H, Zhang Y, Ding Q, Wang SS, Rastogi P, Dai DF, Lu D, Purvis M, Cao C, Wang A, Liu D, Ren C, Elhadi S, Hu MC, Chai Y, Zepeda-Orozco D, Campisi J, Attanasio M. Epithelial innate immunity mediates tubular cell senescence after kidney injury. JCI Insight. 2019 Jan 24; 4: 

                


                  Mapuskar KA, Wen H, Holanda DG, Rastogi P, Steinbach E, Han R, Coleman MC, Attanasio M, Riley DP, Spitz DR, Allen BG, Zepeda-Orozco D. Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease. Redox Biol. 2019 Jan; 20: 98-106.

                


                  Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017 Sep; 5: 

View More Publications

Research

Publications

                  Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29; 11: 

                


                  Mapuskar KA, Steinbach EJ, Zaher A, Riley DP, Beardsley RA, Keene JL, Holmlund JT, Anderson CM, Zepeda-Orozco D, Buatti JM, Spitz DR, Allen BG. Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury. Antioxidants (Basel). 2021 Aug 24; 10: 

                


                  Petronek MS, Steinbach EJ, Kalen AL, Builta ZJ, Callaghan CM, Hyer DE, Spitz DR, Flynn RT, Buatti JM, Magnotta VA, Zepeda-Orozco D, St-Aubin JJ, Allen BG. Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model. Radiat Res. 2021 Mar 1; 195: 230-234.

                


                  Perrenoud L, Kruse NT, Andrews E, You Z, Chonchol M, Wu C, Ten Eyck P, Zepeda-Orozco D, Jalal D. Uric Acid Lowering and Biomarkers of Kidney Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney Med. 2020 Mar-Apr; 2: 155-161.

                


                  Jin H, Zhang Y, Ding Q, Wang SS, Rastogi P, Dai DF, Lu D, Purvis M, Cao C, Wang A, Liu D, Ren C, Elhadi S, Hu MC, Chai Y, Zepeda-Orozco D, Campisi J, Attanasio M. Epithelial innate immunity mediates tubular cell senescence after kidney injury. JCI Insight. 2019 Jan 24; 4: 

                


                  Mapuskar KA, Wen H, Holanda DG, Rastogi P, Steinbach E, Han R, Coleman MC, Attanasio M, Riley DP, Spitz DR, Allen BG, Zepeda-Orozco D. Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease. Redox Biol. 2019 Jan; 20: 98-106.

                


                  Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017 Sep; 5: 

View More Publications

Publications

                  Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29; 11: 

                


                  Mapuskar KA, Steinbach EJ, Zaher A, Riley DP, Beardsley RA, Keene JL, Holmlund JT, Anderson CM, Zepeda-Orozco D, Buatti JM, Spitz DR, Allen BG. Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury. Antioxidants (Basel). 2021 Aug 24; 10: 

                


                  Petronek MS, Steinbach EJ, Kalen AL, Builta ZJ, Callaghan CM, Hyer DE, Spitz DR, Flynn RT, Buatti JM, Magnotta VA, Zepeda-Orozco D, St-Aubin JJ, Allen BG. Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model. Radiat Res. 2021 Mar 1; 195: 230-234.

                


                  Perrenoud L, Kruse NT, Andrews E, You Z, Chonchol M, Wu C, Ten Eyck P, Zepeda-Orozco D, Jalal D. Uric Acid Lowering and Biomarkers of Kidney Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney Med. 2020 Mar-Apr; 2: 155-161.

                


                  Jin H, Zhang Y, Ding Q, Wang SS, Rastogi P, Dai DF, Lu D, Purvis M, Cao C, Wang A, Liu D, Ren C, Elhadi S, Hu MC, Chai Y, Zepeda-Orozco D, Campisi J, Attanasio M. Epithelial innate immunity mediates tubular cell senescence after kidney injury. JCI Insight. 2019 Jan 24; 4: 

                


                  Mapuskar KA, Wen H, Holanda DG, Rastogi P, Steinbach E, Han R, Coleman MC, Attanasio M, Riley DP, Spitz DR, Allen BG, Zepeda-Orozco D. Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease. Redox Biol. 2019 Jan; 20: 98-106.

                


                  Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017 Sep; 5: 

View More Publications

                  Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29; 11: 

                


                  Mapuskar KA, Steinbach EJ, Zaher A, Riley DP, Beardsley RA, Keene JL, Holmlund JT, Anderson CM, Zepeda-Orozco D, Buatti JM, Spitz DR, Allen BG. Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury. Antioxidants (Basel). 2021 Aug 24; 10: 

                


                  Petronek MS, Steinbach EJ, Kalen AL, Builta ZJ, Callaghan CM, Hyer DE, Spitz DR, Flynn RT, Buatti JM, Magnotta VA, Zepeda-Orozco D, St-Aubin JJ, Allen BG. Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model. Radiat Res. 2021 Mar 1; 195: 230-234.

                


                  Perrenoud L, Kruse NT, Andrews E, You Z, Chonchol M, Wu C, Ten Eyck P, Zepeda-Orozco D, Jalal D. Uric Acid Lowering and Biomarkers of Kidney Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney Med. 2020 Mar-Apr; 2: 155-161.

                


                  Jin H, Zhang Y, Ding Q, Wang SS, Rastogi P, Dai DF, Lu D, Purvis M, Cao C, Wang A, Liu D, Ren C, Elhadi S, Hu MC, Chai Y, Zepeda-Orozco D, Campisi J, Attanasio M. Epithelial innate immunity mediates tubular cell senescence after kidney injury. JCI Insight. 2019 Jan 24; 4: 

                


                  Mapuskar KA, Wen H, Holanda DG, Rastogi P, Steinbach E, Han R, Coleman MC, Attanasio M, Riley DP, Spitz DR, Allen BG, Zepeda-Orozco D. Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease. Redox Biol. 2019 Jan; 20: 98-106.

                


                  Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017 Sep; 5: 

View More Publications

• Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29; 11:
• Mapuskar KA, Steinbach EJ, Zaher A, Riley DP, Beardsley RA, Keene JL, Holmlund JT, Anderson CM, Zepeda-Orozco D, Buatti JM, Spitz DR, Allen BG. Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury. Antioxidants (Basel). 2021 Aug 24; 10:
• Petronek MS, Steinbach EJ, Kalen AL, Builta ZJ, Callaghan CM, Hyer DE, Spitz DR, Flynn RT, Buatti JM, Magnotta VA, Zepeda-Orozco D, St-Aubin JJ, Allen BG. Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model. Radiat Res. 2021 Mar 1; 195: 230-234.
• Perrenoud L, Kruse NT, Andrews E, You Z, Chonchol M, Wu C, Ten Eyck P, Zepeda-Orozco D, Jalal D. Uric Acid Lowering and Biomarkers of Kidney Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney Med. 2020 Mar-Apr; 2: 155-161.
• Jin H, Zhang Y, Ding Q, Wang SS, Rastogi P, Dai DF, Lu D, Purvis M, Cao C, Wang A, Liu D, Ren C, Elhadi S, Hu MC, Chai Y, Zepeda-Orozco D, Campisi J, Attanasio M. Epithelial innate immunity mediates tubular cell senescence after kidney injury. JCI Insight. 2019 Jan 24; 4:
• Mapuskar KA, Wen H, Holanda DG, Rastogi P, Steinbach E, Han R, Coleman MC, Attanasio M, Riley DP, Spitz DR, Allen BG, Zepeda-Orozco D. Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease. Redox Biol. 2019 Jan; 20: 98-106.
• Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017 Sep; 5:

Education

Date of Appointment at Nationwide Children’s Hospital: 02/28/2020

Board Certifications

Pediatric Nephrology Pediatrics

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 06/30/2012

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 07/30/2011

Residency

Le Bonheur Children’s Hospital

Date Completed: 06/30/2008

Medical School

University of Guadalajara

Date Completed: 08/01/2004

Education

Date of Appointment at Nationwide Children’s Hospital: 02/28/2020

Board Certifications

Pediatric Nephrology Pediatrics

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 06/30/2012

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 07/30/2011

Residency

Le Bonheur Children’s Hospital

Date Completed: 06/30/2008

Medical School

University of Guadalajara

Date Completed: 08/01/2004

Education

Date of Appointment at Nationwide Children’s Hospital: 02/28/2020

Board Certifications

Pediatric Nephrology Pediatrics

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 06/30/2012

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 07/30/2011

Residency

Le Bonheur Children’s Hospital

Date Completed: 06/30/2008

Medical School

University of Guadalajara

Date Completed: 08/01/2004

Date of Appointment at Nationwide Children’s Hospital: 02/28/2020

Board Certifications

Pediatric Nephrology Pediatrics

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 06/30/2012

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 07/30/2011

Residency

Le Bonheur Children’s Hospital

Date Completed: 06/30/2008

Medical School

University of Guadalajara

Date Completed: 08/01/2004

Date of Appointment at Nationwide Children’s Hospital: 02/28/2020

Board Certifications

Pediatric Nephrology Pediatrics

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 06/30/2012

Fellowship

University of Texas Southwestern Medical Center

Date Completed: 07/30/2011

Residency

Le Bonheur Children’s Hospital

Date Completed: 06/30/2008

Medical School

University of Guadalajara

Date Completed: 08/01/2004

• Pediatric Nephrology
• Pediatrics

Contact Information

Pediatrics

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

                    Nephrology700 Children's DrColumbus, OH 43205 (map)

Contact Information

Pediatrics

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

                    Nephrology700 Children's DrColumbus, OH 43205 (map)

Contact Information

Pediatrics

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

                    Nephrology700 Children's DrColumbus, OH 43205 (map)

Pediatrics

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

                    Nephrology700 Children's DrColumbus, OH 43205 (map)

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

                    Nephrology700 Children's DrColumbus, OH 43205 (map)

Call us at: (614) 722-4360

Fax us at: (614) 722-6482

                    Nephrology700 Children's DrColumbus, OH 43205 (map)

• Call us at:
• (614) 722-4360
• Fax us at:
• (614) 722-6482
• Nephrology700 Children’s DrColumbus, OH 43205 (map)