Contact Information

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack-Yung Yu, D.Phil.

      Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Learn more about Chack-Yung Yu

Academic and Clinical Areas

Center for Microbial Pathogenesis

Principal Investigator

Rheumatology Fellowship

Faculty

Research

Lab(s)

Center for Microbial Pathogenesis

View My Publications

Publications

                  Coss SL, Zhou D, Chua GT, Aziz RA, Hoffman RP, Wu YL, Ardoin SP, Atkinson JP, Yu CY. The complement system and human autoimmune diseases. J Autoimmun. 2022 Dec 17;  102979.

                


                  Zhou D, King EH, Rothwell S, Krystufkova O, Notarnicola A, Coss S, Abdul-Aziz R, Miller KE, Dang A, Yu GR, Drew J, Lundström E, Pachman LM, Mamyrova G, Curiel RV, De Paepe B, De Bleecker JL, Payton A, Ollier W, O'Hanlon TP, Targoff IN, Flegel WA, Sivaraman V, Oberle E, Akoghlanian S, Driest K, Spencer CH, Wu YL, Nagaraja HN, Ardoin SP, Chinoy H, Rider LG, Miller FW, Lundberg IE, Padyukov L, Vencovský J, Lamb JA, Yu CY, for MYOGEN Investigators.. Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies. Ann Rheum Dis. 2022 Sep 28;  

                


                  Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d'Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Johnsen SJA, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K, DISSECT consortium., ImmunoArray consortium., Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Combined genetic deficiencies of the classical complement pathway are strongly associated with both systemic lupus erythematosus and primary Sjögren's syndrome. Arthritis Rheumatol. 2022 Jun 21;  

                


                  Diaz-Gallo LM, Oke V, Lundström E, Elvin K, Ling Wu Y, Eketjäll S, Zickert A, Gustafsson JT, Jönsen A, Leonard D, Birmingham DJ, Nordmark G, Bengtsson AA, Rönnblom L, Gunnarsson I, Yu CY, Padyukov L, Svenungsson E. Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations. ACR Open Rheumatol. 2022 Jan; 4: 27-39.

                


                  Yu CY. A Memory of Professor Robert B. Sim, D. Phil. Viruses. 2021 Aug 9; 13: 

                


                  Toy CR, Song H, Nagaraja HN, Scott J, Greco J, Zhang X, Yu CY, Tumlin JA, Rovin BH, Hebert LA, Birmingham DJ. The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare. Kidney Int Rep. 2021 Aug; 6: 2105-2113.

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Oral glucose tolerance response curve predicts disposition index but not other cardiometabolic risk factors in healthy adolescents. J Pediatr Endocrinol Metab. 2021 May 26; 34: 599-605.

                


                  Yu CY, Ardoin SP. Complement inhibitor for therapy of CHAPLE. Nat Immunol. 2021 Feb; 22: 106-108.

                


                  Zhou D, Rudnicki M, Chua GT, Lawrance SK, Zhou B, Drew JL, Barbar-Smiley F, Armstrong TK, Hilt ME, Birmingham DJ, Passler W, Auletta JJ, Bowden SA, Hoffman RP, Wu YL, Jarjour WN, Mok CC, Ardoin SP, Lau YL, Yu CY. Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases. Front Immunol. 2021; 12: 739430.

                


                  Copenhaver MM, Yu CY, Zhou D, Hoffman RP. Relationships of complement components C3 and C4 and their genetics to cardiometabolic risk in healthy, non-Hispanic white adolescents. Pediatr Res. 2019 Aug 12;  

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Increased body fat and reduced insulin sensitivity are associated with impaired endothelial function and subendocardial viability in healthy, non-Hispanic white adolescents. Pediatr Diabetes. 2019 Jul 22;  

                


                  Mulvihill E, Ardoin S, Thompson SD, Zhou B, Yu GR, King E, Singer N, Levy DM, Brunner H, Wu YL, Nagaraja HN, Schanberg LE, Yu CY. Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE). Lupus Sci Med. 2019; 6: e000333.

                


                  Savelli SL, Roubey RAS, Kitzmiller KJ, Zhou D, Nagaraja HN, Mulvihill E, Barbar-Smiley F, Ardoin SP, Wu YL, Yu CY. Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL). Front Immunol. 2019; 10: 885.

                


                  Copenhaver M, Yu CY, Hoffman RP. Complement Components, C3 and C4, and the Metabolic Syndrome. Curr Diabetes Rev. 2018 Apr 17;

View More Publications

Professional Experience

2006 - Present Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Professor1991 - Present Molecular, Cellular and Development Biology Program, The Ohio State University, Faculty Member1990 - Present The Research Institute at Nationwide Children’s Hospital, Principal Investigator1996 - 2006 Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Associate Professor1990 - 1996 Pediatrics, Medical Microbiology and Immunology, The Ohio State University, Assistant Professor1987 - 1990 MRC Laboratory of Molecular Biology, Research Fellow and Non-Clinical Scientific Staff1983 - 1987 Medical Research Council (MRC) Immunochemistry Unit, Oxford University, Research Student

Contact Information

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack Yung Yu

                    Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Contact Information

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack-Yung Yu, D.Phil.

      Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Learn more about Chack-Yung Yu

Academic and Clinical Areas

Center for Microbial Pathogenesis

Principal Investigator

Rheumatology Fellowship

Faculty

Research

Lab(s)

Center for Microbial Pathogenesis

View My Publications

Publications

                  Coss SL, Zhou D, Chua GT, Aziz RA, Hoffman RP, Wu YL, Ardoin SP, Atkinson JP, Yu CY. The complement system and human autoimmune diseases. J Autoimmun. 2022 Dec 17;  102979.

                


                  Zhou D, King EH, Rothwell S, Krystufkova O, Notarnicola A, Coss S, Abdul-Aziz R, Miller KE, Dang A, Yu GR, Drew J, Lundström E, Pachman LM, Mamyrova G, Curiel RV, De Paepe B, De Bleecker JL, Payton A, Ollier W, O'Hanlon TP, Targoff IN, Flegel WA, Sivaraman V, Oberle E, Akoghlanian S, Driest K, Spencer CH, Wu YL, Nagaraja HN, Ardoin SP, Chinoy H, Rider LG, Miller FW, Lundberg IE, Padyukov L, Vencovský J, Lamb JA, Yu CY, for MYOGEN Investigators.. Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies. Ann Rheum Dis. 2022 Sep 28;  

                


                  Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d'Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Johnsen SJA, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K, DISSECT consortium., ImmunoArray consortium., Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Combined genetic deficiencies of the classical complement pathway are strongly associated with both systemic lupus erythematosus and primary Sjögren's syndrome. Arthritis Rheumatol. 2022 Jun 21;  

                


                  Diaz-Gallo LM, Oke V, Lundström E, Elvin K, Ling Wu Y, Eketjäll S, Zickert A, Gustafsson JT, Jönsen A, Leonard D, Birmingham DJ, Nordmark G, Bengtsson AA, Rönnblom L, Gunnarsson I, Yu CY, Padyukov L, Svenungsson E. Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations. ACR Open Rheumatol. 2022 Jan; 4: 27-39.

                


                  Yu CY. A Memory of Professor Robert B. Sim, D. Phil. Viruses. 2021 Aug 9; 13: 

                


                  Toy CR, Song H, Nagaraja HN, Scott J, Greco J, Zhang X, Yu CY, Tumlin JA, Rovin BH, Hebert LA, Birmingham DJ. The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare. Kidney Int Rep. 2021 Aug; 6: 2105-2113.

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Oral glucose tolerance response curve predicts disposition index but not other cardiometabolic risk factors in healthy adolescents. J Pediatr Endocrinol Metab. 2021 May 26; 34: 599-605.

                


                  Yu CY, Ardoin SP. Complement inhibitor for therapy of CHAPLE. Nat Immunol. 2021 Feb; 22: 106-108.

                


                  Zhou D, Rudnicki M, Chua GT, Lawrance SK, Zhou B, Drew JL, Barbar-Smiley F, Armstrong TK, Hilt ME, Birmingham DJ, Passler W, Auletta JJ, Bowden SA, Hoffman RP, Wu YL, Jarjour WN, Mok CC, Ardoin SP, Lau YL, Yu CY. Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases. Front Immunol. 2021; 12: 739430.

                


                  Copenhaver MM, Yu CY, Zhou D, Hoffman RP. Relationships of complement components C3 and C4 and their genetics to cardiometabolic risk in healthy, non-Hispanic white adolescents. Pediatr Res. 2019 Aug 12;  

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Increased body fat and reduced insulin sensitivity are associated with impaired endothelial function and subendocardial viability in healthy, non-Hispanic white adolescents. Pediatr Diabetes. 2019 Jul 22;  

                


                  Mulvihill E, Ardoin S, Thompson SD, Zhou B, Yu GR, King E, Singer N, Levy DM, Brunner H, Wu YL, Nagaraja HN, Schanberg LE, Yu CY. Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE). Lupus Sci Med. 2019; 6: e000333.

                


                  Savelli SL, Roubey RAS, Kitzmiller KJ, Zhou D, Nagaraja HN, Mulvihill E, Barbar-Smiley F, Ardoin SP, Wu YL, Yu CY. Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL). Front Immunol. 2019; 10: 885.

                


                  Copenhaver M, Yu CY, Hoffman RP. Complement Components, C3 and C4, and the Metabolic Syndrome. Curr Diabetes Rev. 2018 Apr 17;

View More Publications

Professional Experience

2006 - Present Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Professor1991 - Present Molecular, Cellular and Development Biology Program, The Ohio State University, Faculty Member1990 - Present The Research Institute at Nationwide Children’s Hospital, Principal Investigator1996 - 2006 Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Associate Professor1990 - 1996 Pediatrics, Medical Microbiology and Immunology, The Ohio State University, Assistant Professor1987 - 1990 MRC Laboratory of Molecular Biology, Research Fellow and Non-Clinical Scientific Staff1983 - 1987 Medical Research Council (MRC) Immunochemistry Unit, Oxford University, Research Student

Contact Information

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack Yung Yu

                    Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Contact Information

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack-Yung Yu, D.Phil.

      Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Learn more about Chack-Yung Yu

Contact Information

  • Call us at:
  • (614)722.2821
  • Fax us at:
  • (614)722.2817
  • Email Chack-Yung Yu, D.Phil.
  • Abigail Wexner Research Institute700 Children’s DriveColumbus, Ohio 43205 (map)

Learn more about Chack-Yung Yu

Academic and Clinical Areas

Center for Microbial Pathogenesis

Principal Investigator

Rheumatology Fellowship

Faculty

Academic and Clinical Areas

Center for Microbial Pathogenesis

Principal Investigator

Rheumatology Fellowship

Faculty

Academic and Clinical Areas

Center for Microbial Pathogenesis

Principal Investigator

Rheumatology Fellowship

Faculty

Center for Microbial Pathogenesis

Principal Investigator

Rheumatology Fellowship

Faculty

  • Center for Microbial Pathogenesis
  • Principal Investigator
  • Rheumatology Fellowship
  • Faculty

Research

Lab(s)

Center for Microbial Pathogenesis

View My Publications

Publications

                  Coss SL, Zhou D, Chua GT, Aziz RA, Hoffman RP, Wu YL, Ardoin SP, Atkinson JP, Yu CY. The complement system and human autoimmune diseases. J Autoimmun. 2022 Dec 17;  102979.

                


                  Zhou D, King EH, Rothwell S, Krystufkova O, Notarnicola A, Coss S, Abdul-Aziz R, Miller KE, Dang A, Yu GR, Drew J, Lundström E, Pachman LM, Mamyrova G, Curiel RV, De Paepe B, De Bleecker JL, Payton A, Ollier W, O'Hanlon TP, Targoff IN, Flegel WA, Sivaraman V, Oberle E, Akoghlanian S, Driest K, Spencer CH, Wu YL, Nagaraja HN, Ardoin SP, Chinoy H, Rider LG, Miller FW, Lundberg IE, Padyukov L, Vencovský J, Lamb JA, Yu CY, for MYOGEN Investigators.. Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies. Ann Rheum Dis. 2022 Sep 28;  

                


                  Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d'Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Johnsen SJA, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K, DISSECT consortium., ImmunoArray consortium., Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Combined genetic deficiencies of the classical complement pathway are strongly associated with both systemic lupus erythematosus and primary Sjögren's syndrome. Arthritis Rheumatol. 2022 Jun 21;  

                


                  Diaz-Gallo LM, Oke V, Lundström E, Elvin K, Ling Wu Y, Eketjäll S, Zickert A, Gustafsson JT, Jönsen A, Leonard D, Birmingham DJ, Nordmark G, Bengtsson AA, Rönnblom L, Gunnarsson I, Yu CY, Padyukov L, Svenungsson E. Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations. ACR Open Rheumatol. 2022 Jan; 4: 27-39.

                


                  Yu CY. A Memory of Professor Robert B. Sim, D. Phil. Viruses. 2021 Aug 9; 13: 

                


                  Toy CR, Song H, Nagaraja HN, Scott J, Greco J, Zhang X, Yu CY, Tumlin JA, Rovin BH, Hebert LA, Birmingham DJ. The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare. Kidney Int Rep. 2021 Aug; 6: 2105-2113.

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Oral glucose tolerance response curve predicts disposition index but not other cardiometabolic risk factors in healthy adolescents. J Pediatr Endocrinol Metab. 2021 May 26; 34: 599-605.

                


                  Yu CY, Ardoin SP. Complement inhibitor for therapy of CHAPLE. Nat Immunol. 2021 Feb; 22: 106-108.

                


                  Zhou D, Rudnicki M, Chua GT, Lawrance SK, Zhou B, Drew JL, Barbar-Smiley F, Armstrong TK, Hilt ME, Birmingham DJ, Passler W, Auletta JJ, Bowden SA, Hoffman RP, Wu YL, Jarjour WN, Mok CC, Ardoin SP, Lau YL, Yu CY. Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases. Front Immunol. 2021; 12: 739430.

                


                  Copenhaver MM, Yu CY, Zhou D, Hoffman RP. Relationships of complement components C3 and C4 and their genetics to cardiometabolic risk in healthy, non-Hispanic white adolescents. Pediatr Res. 2019 Aug 12;  

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Increased body fat and reduced insulin sensitivity are associated with impaired endothelial function and subendocardial viability in healthy, non-Hispanic white adolescents. Pediatr Diabetes. 2019 Jul 22;  

                


                  Mulvihill E, Ardoin S, Thompson SD, Zhou B, Yu GR, King E, Singer N, Levy DM, Brunner H, Wu YL, Nagaraja HN, Schanberg LE, Yu CY. Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE). Lupus Sci Med. 2019; 6: e000333.

                


                  Savelli SL, Roubey RAS, Kitzmiller KJ, Zhou D, Nagaraja HN, Mulvihill E, Barbar-Smiley F, Ardoin SP, Wu YL, Yu CY. Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL). Front Immunol. 2019; 10: 885.

                


                  Copenhaver M, Yu CY, Hoffman RP. Complement Components, C3 and C4, and the Metabolic Syndrome. Curr Diabetes Rev. 2018 Apr 17;

View More Publications

Research

Lab(s)

Center for Microbial Pathogenesis

View My Publications

Publications

                  Coss SL, Zhou D, Chua GT, Aziz RA, Hoffman RP, Wu YL, Ardoin SP, Atkinson JP, Yu CY. The complement system and human autoimmune diseases. J Autoimmun. 2022 Dec 17;  102979.

                


                  Zhou D, King EH, Rothwell S, Krystufkova O, Notarnicola A, Coss S, Abdul-Aziz R, Miller KE, Dang A, Yu GR, Drew J, Lundström E, Pachman LM, Mamyrova G, Curiel RV, De Paepe B, De Bleecker JL, Payton A, Ollier W, O'Hanlon TP, Targoff IN, Flegel WA, Sivaraman V, Oberle E, Akoghlanian S, Driest K, Spencer CH, Wu YL, Nagaraja HN, Ardoin SP, Chinoy H, Rider LG, Miller FW, Lundberg IE, Padyukov L, Vencovský J, Lamb JA, Yu CY, for MYOGEN Investigators.. Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies. Ann Rheum Dis. 2022 Sep 28;  

                


                  Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d'Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Johnsen SJA, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K, DISSECT consortium., ImmunoArray consortium., Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Combined genetic deficiencies of the classical complement pathway are strongly associated with both systemic lupus erythematosus and primary Sjögren's syndrome. Arthritis Rheumatol. 2022 Jun 21;  

                


                  Diaz-Gallo LM, Oke V, Lundström E, Elvin K, Ling Wu Y, Eketjäll S, Zickert A, Gustafsson JT, Jönsen A, Leonard D, Birmingham DJ, Nordmark G, Bengtsson AA, Rönnblom L, Gunnarsson I, Yu CY, Padyukov L, Svenungsson E. Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations. ACR Open Rheumatol. 2022 Jan; 4: 27-39.

                


                  Yu CY. A Memory of Professor Robert B. Sim, D. Phil. Viruses. 2021 Aug 9; 13: 

                


                  Toy CR, Song H, Nagaraja HN, Scott J, Greco J, Zhang X, Yu CY, Tumlin JA, Rovin BH, Hebert LA, Birmingham DJ. The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare. Kidney Int Rep. 2021 Aug; 6: 2105-2113.

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Oral glucose tolerance response curve predicts disposition index but not other cardiometabolic risk factors in healthy adolescents. J Pediatr Endocrinol Metab. 2021 May 26; 34: 599-605.

                


                  Yu CY, Ardoin SP. Complement inhibitor for therapy of CHAPLE. Nat Immunol. 2021 Feb; 22: 106-108.

                


                  Zhou D, Rudnicki M, Chua GT, Lawrance SK, Zhou B, Drew JL, Barbar-Smiley F, Armstrong TK, Hilt ME, Birmingham DJ, Passler W, Auletta JJ, Bowden SA, Hoffman RP, Wu YL, Jarjour WN, Mok CC, Ardoin SP, Lau YL, Yu CY. Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases. Front Immunol. 2021; 12: 739430.

                


                  Copenhaver MM, Yu CY, Zhou D, Hoffman RP. Relationships of complement components C3 and C4 and their genetics to cardiometabolic risk in healthy, non-Hispanic white adolescents. Pediatr Res. 2019 Aug 12;  

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Increased body fat and reduced insulin sensitivity are associated with impaired endothelial function and subendocardial viability in healthy, non-Hispanic white adolescents. Pediatr Diabetes. 2019 Jul 22;  

                


                  Mulvihill E, Ardoin S, Thompson SD, Zhou B, Yu GR, King E, Singer N, Levy DM, Brunner H, Wu YL, Nagaraja HN, Schanberg LE, Yu CY. Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE). Lupus Sci Med. 2019; 6: e000333.

                


                  Savelli SL, Roubey RAS, Kitzmiller KJ, Zhou D, Nagaraja HN, Mulvihill E, Barbar-Smiley F, Ardoin SP, Wu YL, Yu CY. Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL). Front Immunol. 2019; 10: 885.

                


                  Copenhaver M, Yu CY, Hoffman RP. Complement Components, C3 and C4, and the Metabolic Syndrome. Curr Diabetes Rev. 2018 Apr 17;

View More Publications

Research

Lab(s)

Center for Microbial Pathogenesis

View My Publications

Publications

                  Coss SL, Zhou D, Chua GT, Aziz RA, Hoffman RP, Wu YL, Ardoin SP, Atkinson JP, Yu CY. The complement system and human autoimmune diseases. J Autoimmun. 2022 Dec 17;  102979.

                


                  Zhou D, King EH, Rothwell S, Krystufkova O, Notarnicola A, Coss S, Abdul-Aziz R, Miller KE, Dang A, Yu GR, Drew J, Lundström E, Pachman LM, Mamyrova G, Curiel RV, De Paepe B, De Bleecker JL, Payton A, Ollier W, O'Hanlon TP, Targoff IN, Flegel WA, Sivaraman V, Oberle E, Akoghlanian S, Driest K, Spencer CH, Wu YL, Nagaraja HN, Ardoin SP, Chinoy H, Rider LG, Miller FW, Lundberg IE, Padyukov L, Vencovský J, Lamb JA, Yu CY, for MYOGEN Investigators.. Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies. Ann Rheum Dis. 2022 Sep 28;  

                


                  Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d'Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Johnsen SJA, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K, DISSECT consortium., ImmunoArray consortium., Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Combined genetic deficiencies of the classical complement pathway are strongly associated with both systemic lupus erythematosus and primary Sjögren's syndrome. Arthritis Rheumatol. 2022 Jun 21;  

                


                  Diaz-Gallo LM, Oke V, Lundström E, Elvin K, Ling Wu Y, Eketjäll S, Zickert A, Gustafsson JT, Jönsen A, Leonard D, Birmingham DJ, Nordmark G, Bengtsson AA, Rönnblom L, Gunnarsson I, Yu CY, Padyukov L, Svenungsson E. Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations. ACR Open Rheumatol. 2022 Jan; 4: 27-39.

                


                  Yu CY. A Memory of Professor Robert B. Sim, D. Phil. Viruses. 2021 Aug 9; 13: 

                


                  Toy CR, Song H, Nagaraja HN, Scott J, Greco J, Zhang X, Yu CY, Tumlin JA, Rovin BH, Hebert LA, Birmingham DJ. The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare. Kidney Int Rep. 2021 Aug; 6: 2105-2113.

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Oral glucose tolerance response curve predicts disposition index but not other cardiometabolic risk factors in healthy adolescents. J Pediatr Endocrinol Metab. 2021 May 26; 34: 599-605.

                


                  Yu CY, Ardoin SP. Complement inhibitor for therapy of CHAPLE. Nat Immunol. 2021 Feb; 22: 106-108.

                


                  Zhou D, Rudnicki M, Chua GT, Lawrance SK, Zhou B, Drew JL, Barbar-Smiley F, Armstrong TK, Hilt ME, Birmingham DJ, Passler W, Auletta JJ, Bowden SA, Hoffman RP, Wu YL, Jarjour WN, Mok CC, Ardoin SP, Lau YL, Yu CY. Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases. Front Immunol. 2021; 12: 739430.

                


                  Copenhaver MM, Yu CY, Zhou D, Hoffman RP. Relationships of complement components C3 and C4 and their genetics to cardiometabolic risk in healthy, non-Hispanic white adolescents. Pediatr Res. 2019 Aug 12;  

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Increased body fat and reduced insulin sensitivity are associated with impaired endothelial function and subendocardial viability in healthy, non-Hispanic white adolescents. Pediatr Diabetes. 2019 Jul 22;  

                


                  Mulvihill E, Ardoin S, Thompson SD, Zhou B, Yu GR, King E, Singer N, Levy DM, Brunner H, Wu YL, Nagaraja HN, Schanberg LE, Yu CY. Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE). Lupus Sci Med. 2019; 6: e000333.

                


                  Savelli SL, Roubey RAS, Kitzmiller KJ, Zhou D, Nagaraja HN, Mulvihill E, Barbar-Smiley F, Ardoin SP, Wu YL, Yu CY. Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL). Front Immunol. 2019; 10: 885.

                


                  Copenhaver M, Yu CY, Hoffman RP. Complement Components, C3 and C4, and the Metabolic Syndrome. Curr Diabetes Rev. 2018 Apr 17;

View More Publications

Lab(s)

Center for Microbial Pathogenesis

View My Publications

Publications

                  Coss SL, Zhou D, Chua GT, Aziz RA, Hoffman RP, Wu YL, Ardoin SP, Atkinson JP, Yu CY. The complement system and human autoimmune diseases. J Autoimmun. 2022 Dec 17;  102979.

                


                  Zhou D, King EH, Rothwell S, Krystufkova O, Notarnicola A, Coss S, Abdul-Aziz R, Miller KE, Dang A, Yu GR, Drew J, Lundström E, Pachman LM, Mamyrova G, Curiel RV, De Paepe B, De Bleecker JL, Payton A, Ollier W, O'Hanlon TP, Targoff IN, Flegel WA, Sivaraman V, Oberle E, Akoghlanian S, Driest K, Spencer CH, Wu YL, Nagaraja HN, Ardoin SP, Chinoy H, Rider LG, Miller FW, Lundberg IE, Padyukov L, Vencovský J, Lamb JA, Yu CY, for MYOGEN Investigators.. Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies. Ann Rheum Dis. 2022 Sep 28;  

                


                  Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d'Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Johnsen SJA, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K, DISSECT consortium., ImmunoArray consortium., Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Combined genetic deficiencies of the classical complement pathway are strongly associated with both systemic lupus erythematosus and primary Sjögren's syndrome. Arthritis Rheumatol. 2022 Jun 21;  

                


                  Diaz-Gallo LM, Oke V, Lundström E, Elvin K, Ling Wu Y, Eketjäll S, Zickert A, Gustafsson JT, Jönsen A, Leonard D, Birmingham DJ, Nordmark G, Bengtsson AA, Rönnblom L, Gunnarsson I, Yu CY, Padyukov L, Svenungsson E. Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations. ACR Open Rheumatol. 2022 Jan; 4: 27-39.

                


                  Yu CY. A Memory of Professor Robert B. Sim, D. Phil. Viruses. 2021 Aug 9; 13: 

                


                  Toy CR, Song H, Nagaraja HN, Scott J, Greco J, Zhang X, Yu CY, Tumlin JA, Rovin BH, Hebert LA, Birmingham DJ. The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare. Kidney Int Rep. 2021 Aug; 6: 2105-2113.

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Oral glucose tolerance response curve predicts disposition index but not other cardiometabolic risk factors in healthy adolescents. J Pediatr Endocrinol Metab. 2021 May 26; 34: 599-605.

                


                  Yu CY, Ardoin SP. Complement inhibitor for therapy of CHAPLE. Nat Immunol. 2021 Feb; 22: 106-108.

                


                  Zhou D, Rudnicki M, Chua GT, Lawrance SK, Zhou B, Drew JL, Barbar-Smiley F, Armstrong TK, Hilt ME, Birmingham DJ, Passler W, Auletta JJ, Bowden SA, Hoffman RP, Wu YL, Jarjour WN, Mok CC, Ardoin SP, Lau YL, Yu CY. Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases. Front Immunol. 2021; 12: 739430.

                


                  Copenhaver MM, Yu CY, Zhou D, Hoffman RP. Relationships of complement components C3 and C4 and their genetics to cardiometabolic risk in healthy, non-Hispanic white adolescents. Pediatr Res. 2019 Aug 12;  

                


                  Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Increased body fat and reduced insulin sensitivity are associated with impaired endothelial function and subendocardial viability in healthy, non-Hispanic white adolescents. Pediatr Diabetes. 2019 Jul 22;  

                


                  Mulvihill E, Ardoin S, Thompson SD, Zhou B, Yu GR, King E, Singer N, Levy DM, Brunner H, Wu YL, Nagaraja HN, Schanberg LE, Yu CY. Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE). Lupus Sci Med. 2019; 6: e000333.

                


                  Savelli SL, Roubey RAS, Kitzmiller KJ, Zhou D, Nagaraja HN, Mulvihill E, Barbar-Smiley F, Ardoin SP, Wu YL, Yu CY. Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL). Front Immunol. 2019; 10: 885.

                


                  Copenhaver M, Yu CY, Hoffman RP. Complement Components, C3 and C4, and the Metabolic Syndrome. Curr Diabetes Rev. 2018 Apr 17;

View More Publications

Lab(s)

Center for Microbial Pathogenesis

  • View My Publications

                    Coss SL, Zhou D, Chua GT, Aziz RA, Hoffman RP, Wu YL, Ardoin SP, Atkinson JP, Yu CY. The complement system and human autoimmune diseases. J Autoimmun. 2022 Dec 17;  102979.



                Zhou D, King EH, Rothwell S, Krystufkova O, Notarnicola A, Coss S, Abdul-Aziz R, Miller KE, Dang A, Yu GR, Drew J, Lundström E, Pachman LM, Mamyrova G, Curiel RV, De Paepe B, De Bleecker JL, Payton A, Ollier W, O'Hanlon TP, Targoff IN, Flegel WA, Sivaraman V, Oberle E, Akoghlanian S, Driest K, Spencer CH, Wu YL, Nagaraja HN, Ardoin SP, Chinoy H, Rider LG, Miller FW, Lundberg IE, Padyukov L, Vencovský J, Lamb JA, Yu CY, for MYOGEN Investigators.. Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies. Ann Rheum Dis. 2022 Sep 28;  



                Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d'Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Johnsen SJA, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K, DISSECT consortium., ImmunoArray consortium., Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Combined genetic deficiencies of the classical complement pathway are strongly associated with both systemic lupus erythematosus and primary Sjögren's syndrome. Arthritis Rheumatol. 2022 Jun 21;  



                Diaz-Gallo LM, Oke V, Lundström E, Elvin K, Ling Wu Y, Eketjäll S, Zickert A, Gustafsson JT, Jönsen A, Leonard D, Birmingham DJ, Nordmark G, Bengtsson AA, Rönnblom L, Gunnarsson I, Yu CY, Padyukov L, Svenungsson E. Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations. ACR Open Rheumatol. 2022 Jan; 4: 27-39.



                Yu CY. A Memory of Professor Robert B. Sim, D. Phil. Viruses. 2021 Aug 9; 13: 



                Toy CR, Song H, Nagaraja HN, Scott J, Greco J, Zhang X, Yu CY, Tumlin JA, Rovin BH, Hebert LA, Birmingham DJ. The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare. Kidney Int Rep. 2021 Aug; 6: 2105-2113.



                Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Oral glucose tolerance response curve predicts disposition index but not other cardiometabolic risk factors in healthy adolescents. J Pediatr Endocrinol Metab. 2021 May 26; 34: 599-605.



                Yu CY, Ardoin SP. Complement inhibitor for therapy of CHAPLE. Nat Immunol. 2021 Feb; 22: 106-108.



                Zhou D, Rudnicki M, Chua GT, Lawrance SK, Zhou B, Drew JL, Barbar-Smiley F, Armstrong TK, Hilt ME, Birmingham DJ, Passler W, Auletta JJ, Bowden SA, Hoffman RP, Wu YL, Jarjour WN, Mok CC, Ardoin SP, Lau YL, Yu CY. Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases. Front Immunol. 2021; 12: 739430.



                Copenhaver MM, Yu CY, Zhou D, Hoffman RP. Relationships of complement components C3 and C4 and their genetics to cardiometabolic risk in healthy, non-Hispanic white adolescents. Pediatr Res. 2019 Aug 12;  



                Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Increased body fat and reduced insulin sensitivity are associated with impaired endothelial function and subendocardial viability in healthy, non-Hispanic white adolescents. Pediatr Diabetes. 2019 Jul 22;  



                Mulvihill E, Ardoin S, Thompson SD, Zhou B, Yu GR, King E, Singer N, Levy DM, Brunner H, Wu YL, Nagaraja HN, Schanberg LE, Yu CY. Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE). Lupus Sci Med. 2019; 6: e000333.



                Savelli SL, Roubey RAS, Kitzmiller KJ, Zhou D, Nagaraja HN, Mulvihill E, Barbar-Smiley F, Ardoin SP, Wu YL, Yu CY. Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL). Front Immunol. 2019; 10: 885.



                Copenhaver M, Yu CY, Hoffman RP. Complement Components, C3 and C4, and the Metabolic Syndrome. Curr Diabetes Rev. 2018 Apr 17;

View More Publications

Lab(s)

Center for Microbial Pathogenesis

  • Center for Microbial Pathogenesis

  • Coss SL, Zhou D, Chua GT, Aziz RA, Hoffman RP, Wu YL, Ardoin SP, Atkinson JP, Yu CY. The complement system and human autoimmune diseases. J Autoimmun. 2022 Dec 17; 102979.

  • Zhou D, King EH, Rothwell S, Krystufkova O, Notarnicola A, Coss S, Abdul-Aziz R, Miller KE, Dang A, Yu GR, Drew J, Lundström E, Pachman LM, Mamyrova G, Curiel RV, De Paepe B, De Bleecker JL, Payton A, Ollier W, O’Hanlon TP, Targoff IN, Flegel WA, Sivaraman V, Oberle E, Akoghlanian S, Driest K, Spencer CH, Wu YL, Nagaraja HN, Ardoin SP, Chinoy H, Rider LG, Miller FW, Lundberg IE, Padyukov L, Vencovský J, Lamb JA, Yu CY, for MYOGEN Investigators.. Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies. Ann Rheum Dis. 2022 Sep 28;

  • Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d’Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Johnsen SJA, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K, DISSECT consortium., ImmunoArray consortium., Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Combined genetic deficiencies of the classical complement pathway are strongly associated with both systemic lupus erythematosus and primary Sjögren’s syndrome. Arthritis Rheumatol. 2022 Jun 21;

  • Diaz-Gallo LM, Oke V, Lundström E, Elvin K, Ling Wu Y, Eketjäll S, Zickert A, Gustafsson JT, Jönsen A, Leonard D, Birmingham DJ, Nordmark G, Bengtsson AA, Rönnblom L, Gunnarsson I, Yu CY, Padyukov L, Svenungsson E. Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations. ACR Open Rheumatol. 2022 Jan; 4: 27-39.

  • Yu CY. A Memory of Professor Robert B. Sim, D. Phil. Viruses. 2021 Aug 9; 13:

  • Toy CR, Song H, Nagaraja HN, Scott J, Greco J, Zhang X, Yu CY, Tumlin JA, Rovin BH, Hebert LA, Birmingham DJ. The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare. Kidney Int Rep. 2021 Aug; 6: 2105-2113.

  • Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Oral glucose tolerance response curve predicts disposition index but not other cardiometabolic risk factors in healthy adolescents. J Pediatr Endocrinol Metab. 2021 May 26; 34: 599-605.

  • Yu CY, Ardoin SP. Complement inhibitor for therapy of CHAPLE. Nat Immunol. 2021 Feb; 22: 106-108.

  • Zhou D, Rudnicki M, Chua GT, Lawrance SK, Zhou B, Drew JL, Barbar-Smiley F, Armstrong TK, Hilt ME, Birmingham DJ, Passler W, Auletta JJ, Bowden SA, Hoffman RP, Wu YL, Jarjour WN, Mok CC, Ardoin SP, Lau YL, Yu CY. Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases. Front Immunol. 2021; 12: 739430.

  • Copenhaver MM, Yu CY, Zhou D, Hoffman RP. Relationships of complement components C3 and C4 and their genetics to cardiometabolic risk in healthy, non-Hispanic white adolescents. Pediatr Res. 2019 Aug 12;

  • Hoffman RP, Copenhaver MM, Zhou D, Yu CY. Increased body fat and reduced insulin sensitivity are associated with impaired endothelial function and subendocardial viability in healthy, non-Hispanic white adolescents. Pediatr Diabetes. 2019 Jul 22;

  • Mulvihill E, Ardoin S, Thompson SD, Zhou B, Yu GR, King E, Singer N, Levy DM, Brunner H, Wu YL, Nagaraja HN, Schanberg LE, Yu CY. Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE). Lupus Sci Med. 2019; 6: e000333.

  • Savelli SL, Roubey RAS, Kitzmiller KJ, Zhou D, Nagaraja HN, Mulvihill E, Barbar-Smiley F, Ardoin SP, Wu YL, Yu CY. Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL). Front Immunol. 2019; 10: 885.

  • Copenhaver M, Yu CY, Hoffman RP. Complement Components, C3 and C4, and the Metabolic Syndrome. Curr Diabetes Rev. 2018 Apr 17;

Professional Experience

2006 - Present Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Professor1991 - Present Molecular, Cellular and Development Biology Program, The Ohio State University, Faculty Member1990 - Present The Research Institute at Nationwide Children’s Hospital, Principal Investigator1996 - 2006 Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Associate Professor1990 - 1996 Pediatrics, Medical Microbiology and Immunology, The Ohio State University, Assistant Professor1987 - 1990 MRC Laboratory of Molecular Biology, Research Fellow and Non-Clinical Scientific Staff1983 - 1987 Medical Research Council (MRC) Immunochemistry Unit, Oxford University, Research Student

Professional Experience

2006 - Present Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Professor1991 - Present Molecular, Cellular and Development Biology Program, The Ohio State University, Faculty Member1990 - Present The Research Institute at Nationwide Children’s Hospital, Principal Investigator1996 - 2006 Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Associate Professor1990 - 1996 Pediatrics, Medical Microbiology and Immunology, The Ohio State University, Assistant Professor1987 - 1990 MRC Laboratory of Molecular Biology, Research Fellow and Non-Clinical Scientific Staff1983 - 1987 Medical Research Council (MRC) Immunochemistry Unit, Oxford University, Research Student

Professional Experience

2006 - Present Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Professor1991 - Present Molecular, Cellular and Development Biology Program, The Ohio State University, Faculty Member1990 - Present The Research Institute at Nationwide Children’s Hospital, Principal Investigator1996 - 2006 Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Associate Professor1990 - 1996 Pediatrics, Medical Microbiology and Immunology, The Ohio State University, Assistant Professor1987 - 1990 MRC Laboratory of Molecular Biology, Research Fellow and Non-Clinical Scientific Staff1983 - 1987 Medical Research Council (MRC) Immunochemistry Unit, Oxford University, Research Student

2006 - Present Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Professor1991 - Present Molecular, Cellular and Development Biology Program, The Ohio State University, Faculty Member1990 - Present The Research Institute at Nationwide Children’s Hospital, Principal Investigator1996 - 2006 Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Associate Professor1990 - 1996 Pediatrics, Medical Microbiology and Immunology, The Ohio State University, Assistant Professor1987 - 1990 MRC Laboratory of Molecular Biology, Research Fellow and Non-Clinical Scientific Staff1983 - 1987 Medical Research Council (MRC) Immunochemistry Unit, Oxford University, Research Student

2006 - Present Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Professor

Contact Information

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack Yung Yu

                    Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Contact Information

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack Yung Yu

                    Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Contact Information

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack Yung Yu

                    Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack Yung Yu

                    Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack Yung Yu

                    Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)

Call us at: (614)722.2821

Fax us at: (614)722.2817

Email Chack Yung Yu

                    Abigail Wexner Research Institute700 Children's DriveColumbus, Ohio 43205 (map)
  • Call us at:
  • (614)722.2821
  • Fax us at:
  • (614)722.2817
  • Email Chack Yung Yu
  • Abigail Wexner Research Institute700 Children’s DriveColumbus, Ohio 43205 (map)