Amit Kapoor

Contact Information

Call us at: (614)722-2735

Fax us at: (614)722-3680

Center for Vaccines and Immunity700 Children’s DriveRoom WA4015Columbus, OH 43205 (map)

Learn more about Amit Kapoor

Research

Lab(s)

Center for Vaccines and Immunity

Dr. Kapoor identified the first non-primate homologs of Hepatitis C virus, including the well-known equine and rodent hepaciviruses. Absent immune-competent animal models for HCV, homolog hepaciviruses in their natural hosts could provide useful surrogate models to understand HCV pathogenesis and immunity. Currently, Dr Kapoor’s lab is characterizing the biological properties of these new HCV-like animal viruses using in vitro and reverse genetic systems paving the way for their detailed in vivo characterization. His main focus is to use these surrogate models to identify the determinants of HCV persistence and protective immunity.

View My Publications

Publications

                  Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters. J Virol. 2021 Sep 27; 95: e0059221.

                


                  Tomlinson JE, Wolfisberg R, Fahnøe U, Patel RS, Trivedi S, Kumar A, Sharma H, Nielsen L, McDonough SP, Bukh J, Tennant BC, Kapoor A, Rosenberg BR, Rice CM, Divers TJ, Van de Walle GR, Scheel TKH. Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology. 2021 Sep; 74: 1148-1163.

                


                  Hartlage AS, Kapoor A. Hepatitis C Virus Vaccine Research: Time to Put Up or Shut Up. Viruses. 2021 Aug 12; 13: 

                


                  Erdem G, Kaptsan I, Sharma H, Kumar A, Aylward SC, Kapoor A, Shimamura M. Cerebrospinal Fluid Analysis for Viruses by Metagenomic Next-Generation Sequencing in Pediatric Encephalitis: Not Yet Ready for Prime Time? J Child Neurol. 2021 Apr; 36: 350-356.

                


                  Hartlage AS, Dravid P, Walker CM, Kapoor A. Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats. PLoS Pathog. 2021 Mar; 17: e1009391.

                


                  Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike. Proc Natl Acad Sci U S A. 2021 Mar 23; 118: 

                


                  Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunisation strategies for HCV. Hepatology. 2019 Aug 10;  

                


                  Wolfisberg R, Holmbeck K, Nielsen L, Kapoor A, Rice CM, Bukh J, Scheel TKH. Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells. J Virol. 2019 Jul 10;  

                


                  Vandegrift KJ, Kapoor A. The Ecology of New Constituents of the Tick Virome and Their Relevance to Public Health. Viruses. 2019 Jun 7; 11: 

                


                  Hartlage AS, Murthy S, Kumar A, Trivedi S, Dravid P, Sharma H, Walker CM, Kapoor A. Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection. Nat Commun. 2019 Mar 7; 10: 1113.

                


                  Tomlinson JE, Kapoor A, Kumar A, Tennant BC, Laverack MA, Beard L, Delph K, Davis E, Schott Ii H, Lascola K, Holbrook TC, Johnson P, Taylor SD, McKenzie E, Carter-Arnold J, Setlakwe E, Fultz L, Brakenhoff J, Ruby R, Trivedi S, Van de Walle GR, Renshaw RW, Dubovi EJ, Divers TJ. Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 251-257.

                


                  Tomlinson JE, Tennant BC, Struzyna A, Mrad D, Browne N, Whelchel D, Johnson PJ, Jamieson C, Löhr CV, Bildfell R, McKenzie EC, Laverack M, Renshaw RW, Dubovi E, Kapoor A, Meirs RS, Belgrave R, Engiles J, Van de Walle GR, Divers TJ. Viral testing of 10 cases of Theiler's disease and 37 in-contact horses in the absence of equine biologic product administration: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 258-265.

                


                  Yu Y, Scheel TKH, Luna JM, Chung H, Nishiuchi E, Scull MA, Echeverría N, Ricardo-Lax I, Kapoor A, Lipkin WI, Divers TJ, Antczak DF, Tennant BC, Rice CM. Correction: miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathog. 2018 Sep; 14: e1007303.

                


                  Trivedi S, Murthy S, Sharma H, Hartlage AS, Kumar A, Gadi SV, Simmonds P, Chauhan LV, Scheel TKH, Billerbeck E, Burbelo PD, Rice CM, Lipkin WI, Vandegrift K, Cullen JM, Kapoor A. Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model. Hepatology. 2018 Aug; 68: 435-448.

                


                  Divers TJ, Tennant BC, Kumar A, McDonough S, Cullen J, Bhuva N, Jain K, Chauhan LS, Scheel TKH, Lipkin WI, Laverack M, Trivedi S, Srinivasa S, Beard L, Rice CM, Burbelo PD, Renshaw RW, Dubovi E, Kapoor A. New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product. Emerg Infect Dis. 2018 Feb; 24: 303-310.

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Biography

In 2015, Amit Kapoor, PhD, joined The Center for Vaccines & Immunity at The Research Institute at Nationwide Children’s Hospital as a principal investigator and The Ohio State University Department of Pediatrics as an Associate Professor. Dr. Kapoor’s work focuses on molecular characterization of polio and enteroviruses associated with acute flaccid paralysis in North Indian children. This work was part of an effort to eradicate wild polioviruses from India using vaccination and surveillance. Dr. Kapoor joined Dr. Eric Delwart (UCSF) in 2002 as post doc and helped in the identification of several new human and animal viruses, including human cosavirus, bocaviruses, astroviruses, parvoviruses and picornaviruses. Dr. Kapoor joined Columbia University as Assistant professor in 2010, where he identified more new human and animal viruses including the first non- human primate homologs of Hepatitis C virus. His most recent work was the identification of human hepegivirus (also known as Human Pegivirus 2) in blood transfusion recipients and the development of VirCapSeq (a pan virome sequencing enrichment method, similar to the exon capture method).

Academic and Clinical Areas

Center for Vaccines and Immunity

Principal Investigator

Primary Department

Center for Vaccines and Immunity

Awards, Honors & Organizations

One of two PNAS papers selected for the section “In this issue” and both articles were accompanied by commentaries Guest appearance, twice, “This week in virology” (TWiV.tv) – a widely popular science podcast Work highlighted by New York Times and other science media sites Two Journal of Virology papers selected for “Spotlight” section Work featured as cover page of The Journal of Infectious diseases and the ASM Journal mBio Journal of Virology paper selected, Faculty of 1000 Biology

Professional Experience

2015 - Present Vaccines & Immunity Center, The Research Institute at Nationwide Children’s Hospital,, Principal Investigator2015 - Present Department of Pediatrics, The Ohio State University,, Associate Professor2010 - 2015 Pathology & Cell Biology, Columbia University,, Assistant Professor2010 - 2010 Infection & Immunity Center, Columbia University,, Associate Research Scientist2006 - 2009 Molecular Virology, Blood Systems Research Institute, University of California,, Scientist

Contact Information

Center for Vaccines and Immunity

Call us at: (614)722-2735

Fax us at: (614)722-3680

                    700 Children's DriveRoom WA4015Columbus, OH 43205 (map)

Contact Information

Call us at: (614)722-2735

Fax us at: (614)722-3680

Center for Vaccines and Immunity700 Children’s DriveRoom WA4015Columbus, OH 43205 (map)

Learn more about Amit Kapoor

Research

Lab(s)

Center for Vaccines and Immunity

View My Publications

Publications

                  Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters. J Virol. 2021 Sep 27; 95: e0059221.

                


                  Tomlinson JE, Wolfisberg R, Fahnøe U, Patel RS, Trivedi S, Kumar A, Sharma H, Nielsen L, McDonough SP, Bukh J, Tennant BC, Kapoor A, Rosenberg BR, Rice CM, Divers TJ, Van de Walle GR, Scheel TKH. Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology. 2021 Sep; 74: 1148-1163.

                


                  Hartlage AS, Kapoor A. Hepatitis C Virus Vaccine Research: Time to Put Up or Shut Up. Viruses. 2021 Aug 12; 13: 

                


                  Erdem G, Kaptsan I, Sharma H, Kumar A, Aylward SC, Kapoor A, Shimamura M. Cerebrospinal Fluid Analysis for Viruses by Metagenomic Next-Generation Sequencing in Pediatric Encephalitis: Not Yet Ready for Prime Time? J Child Neurol. 2021 Apr; 36: 350-356.

                


                  Hartlage AS, Dravid P, Walker CM, Kapoor A. Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats. PLoS Pathog. 2021 Mar; 17: e1009391.

                


                  Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike. Proc Natl Acad Sci U S A. 2021 Mar 23; 118: 

                


                  Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunisation strategies for HCV. Hepatology. 2019 Aug 10;  

                


                  Wolfisberg R, Holmbeck K, Nielsen L, Kapoor A, Rice CM, Bukh J, Scheel TKH. Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells. J Virol. 2019 Jul 10;  

                


                  Vandegrift KJ, Kapoor A. The Ecology of New Constituents of the Tick Virome and Their Relevance to Public Health. Viruses. 2019 Jun 7; 11: 

                


                  Hartlage AS, Murthy S, Kumar A, Trivedi S, Dravid P, Sharma H, Walker CM, Kapoor A. Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection. Nat Commun. 2019 Mar 7; 10: 1113.

                


                  Tomlinson JE, Kapoor A, Kumar A, Tennant BC, Laverack MA, Beard L, Delph K, Davis E, Schott Ii H, Lascola K, Holbrook TC, Johnson P, Taylor SD, McKenzie E, Carter-Arnold J, Setlakwe E, Fultz L, Brakenhoff J, Ruby R, Trivedi S, Van de Walle GR, Renshaw RW, Dubovi EJ, Divers TJ. Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 251-257.

                


                  Tomlinson JE, Tennant BC, Struzyna A, Mrad D, Browne N, Whelchel D, Johnson PJ, Jamieson C, Löhr CV, Bildfell R, McKenzie EC, Laverack M, Renshaw RW, Dubovi E, Kapoor A, Meirs RS, Belgrave R, Engiles J, Van de Walle GR, Divers TJ. Viral testing of 10 cases of Theiler's disease and 37 in-contact horses in the absence of equine biologic product administration: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 258-265.

                


                  Yu Y, Scheel TKH, Luna JM, Chung H, Nishiuchi E, Scull MA, Echeverría N, Ricardo-Lax I, Kapoor A, Lipkin WI, Divers TJ, Antczak DF, Tennant BC, Rice CM. Correction: miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathog. 2018 Sep; 14: e1007303.

                


                  Trivedi S, Murthy S, Sharma H, Hartlage AS, Kumar A, Gadi SV, Simmonds P, Chauhan LV, Scheel TKH, Billerbeck E, Burbelo PD, Rice CM, Lipkin WI, Vandegrift K, Cullen JM, Kapoor A. Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model. Hepatology. 2018 Aug; 68: 435-448.

                


                  Divers TJ, Tennant BC, Kumar A, McDonough S, Cullen J, Bhuva N, Jain K, Chauhan LS, Scheel TKH, Lipkin WI, Laverack M, Trivedi S, Srinivasa S, Beard L, Rice CM, Burbelo PD, Renshaw RW, Dubovi E, Kapoor A. New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product. Emerg Infect Dis. 2018 Feb; 24: 303-310.

View More Publications

Biography

Academic and Clinical Areas

Center for Vaccines and Immunity

Principal Investigator

Primary Department

Center for Vaccines and Immunity

Awards, Honors & Organizations

Professional Experience

Contact Information

Center for Vaccines and Immunity

Call us at: (614)722-2735

Fax us at: (614)722-3680

                    700 Children's DriveRoom WA4015Columbus, OH 43205 (map)

Contact Information

Call us at: (614)722-2735

Fax us at: (614)722-3680

Center for Vaccines and Immunity700 Children’s DriveRoom WA4015Columbus, OH 43205 (map)

Learn more about Amit Kapoor

Contact Information

Call us at:
(614)722-2735
Fax us at:
(614)722-3680
Center for Vaccines and Immunity700 Children’s DriveRoom WA4015Columbus, OH 43205 (map)

Learn more about Amit Kapoor

Research

Lab(s)

Center for Vaccines and Immunity

View My Publications

Publications

                  Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters. J Virol. 2021 Sep 27; 95: e0059221.

                


                  Tomlinson JE, Wolfisberg R, Fahnøe U, Patel RS, Trivedi S, Kumar A, Sharma H, Nielsen L, McDonough SP, Bukh J, Tennant BC, Kapoor A, Rosenberg BR, Rice CM, Divers TJ, Van de Walle GR, Scheel TKH. Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology. 2021 Sep; 74: 1148-1163.

                


                  Hartlage AS, Kapoor A. Hepatitis C Virus Vaccine Research: Time to Put Up or Shut Up. Viruses. 2021 Aug 12; 13: 

                


                  Erdem G, Kaptsan I, Sharma H, Kumar A, Aylward SC, Kapoor A, Shimamura M. Cerebrospinal Fluid Analysis for Viruses by Metagenomic Next-Generation Sequencing in Pediatric Encephalitis: Not Yet Ready for Prime Time? J Child Neurol. 2021 Apr; 36: 350-356.

                


                  Hartlage AS, Dravid P, Walker CM, Kapoor A. Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats. PLoS Pathog. 2021 Mar; 17: e1009391.

                


                  Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike. Proc Natl Acad Sci U S A. 2021 Mar 23; 118: 

                


                  Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunisation strategies for HCV. Hepatology. 2019 Aug 10;  

                


                  Wolfisberg R, Holmbeck K, Nielsen L, Kapoor A, Rice CM, Bukh J, Scheel TKH. Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells. J Virol. 2019 Jul 10;  

                


                  Vandegrift KJ, Kapoor A. The Ecology of New Constituents of the Tick Virome and Their Relevance to Public Health. Viruses. 2019 Jun 7; 11: 

                


                  Hartlage AS, Murthy S, Kumar A, Trivedi S, Dravid P, Sharma H, Walker CM, Kapoor A. Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection. Nat Commun. 2019 Mar 7; 10: 1113.

                


                  Tomlinson JE, Kapoor A, Kumar A, Tennant BC, Laverack MA, Beard L, Delph K, Davis E, Schott Ii H, Lascola K, Holbrook TC, Johnson P, Taylor SD, McKenzie E, Carter-Arnold J, Setlakwe E, Fultz L, Brakenhoff J, Ruby R, Trivedi S, Van de Walle GR, Renshaw RW, Dubovi EJ, Divers TJ. Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 251-257.

                


                  Tomlinson JE, Tennant BC, Struzyna A, Mrad D, Browne N, Whelchel D, Johnson PJ, Jamieson C, Löhr CV, Bildfell R, McKenzie EC, Laverack M, Renshaw RW, Dubovi E, Kapoor A, Meirs RS, Belgrave R, Engiles J, Van de Walle GR, Divers TJ. Viral testing of 10 cases of Theiler's disease and 37 in-contact horses in the absence of equine biologic product administration: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 258-265.

                


                  Yu Y, Scheel TKH, Luna JM, Chung H, Nishiuchi E, Scull MA, Echeverría N, Ricardo-Lax I, Kapoor A, Lipkin WI, Divers TJ, Antczak DF, Tennant BC, Rice CM. Correction: miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathog. 2018 Sep; 14: e1007303.

                


                  Trivedi S, Murthy S, Sharma H, Hartlage AS, Kumar A, Gadi SV, Simmonds P, Chauhan LV, Scheel TKH, Billerbeck E, Burbelo PD, Rice CM, Lipkin WI, Vandegrift K, Cullen JM, Kapoor A. Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model. Hepatology. 2018 Aug; 68: 435-448.

                


                  Divers TJ, Tennant BC, Kumar A, McDonough S, Cullen J, Bhuva N, Jain K, Chauhan LS, Scheel TKH, Lipkin WI, Laverack M, Trivedi S, Srinivasa S, Beard L, Rice CM, Burbelo PD, Renshaw RW, Dubovi E, Kapoor A. New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product. Emerg Infect Dis. 2018 Feb; 24: 303-310.

View More Publications

Research

Lab(s)

Center for Vaccines and Immunity

View My Publications

Publications

                  Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters. J Virol. 2021 Sep 27; 95: e0059221.

                


                  Tomlinson JE, Wolfisberg R, Fahnøe U, Patel RS, Trivedi S, Kumar A, Sharma H, Nielsen L, McDonough SP, Bukh J, Tennant BC, Kapoor A, Rosenberg BR, Rice CM, Divers TJ, Van de Walle GR, Scheel TKH. Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology. 2021 Sep; 74: 1148-1163.

                


                  Hartlage AS, Kapoor A. Hepatitis C Virus Vaccine Research: Time to Put Up or Shut Up. Viruses. 2021 Aug 12; 13: 

                


                  Erdem G, Kaptsan I, Sharma H, Kumar A, Aylward SC, Kapoor A, Shimamura M. Cerebrospinal Fluid Analysis for Viruses by Metagenomic Next-Generation Sequencing in Pediatric Encephalitis: Not Yet Ready for Prime Time? J Child Neurol. 2021 Apr; 36: 350-356.

                


                  Hartlage AS, Dravid P, Walker CM, Kapoor A. Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats. PLoS Pathog. 2021 Mar; 17: e1009391.

                


                  Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike. Proc Natl Acad Sci U S A. 2021 Mar 23; 118: 

                


                  Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunisation strategies for HCV. Hepatology. 2019 Aug 10;  

                


                  Wolfisberg R, Holmbeck K, Nielsen L, Kapoor A, Rice CM, Bukh J, Scheel TKH. Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells. J Virol. 2019 Jul 10;  

                


                  Vandegrift KJ, Kapoor A. The Ecology of New Constituents of the Tick Virome and Their Relevance to Public Health. Viruses. 2019 Jun 7; 11: 

                


                  Hartlage AS, Murthy S, Kumar A, Trivedi S, Dravid P, Sharma H, Walker CM, Kapoor A. Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection. Nat Commun. 2019 Mar 7; 10: 1113.

                


                  Tomlinson JE, Kapoor A, Kumar A, Tennant BC, Laverack MA, Beard L, Delph K, Davis E, Schott Ii H, Lascola K, Holbrook TC, Johnson P, Taylor SD, McKenzie E, Carter-Arnold J, Setlakwe E, Fultz L, Brakenhoff J, Ruby R, Trivedi S, Van de Walle GR, Renshaw RW, Dubovi EJ, Divers TJ. Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 251-257.

                


                  Tomlinson JE, Tennant BC, Struzyna A, Mrad D, Browne N, Whelchel D, Johnson PJ, Jamieson C, Löhr CV, Bildfell R, McKenzie EC, Laverack M, Renshaw RW, Dubovi E, Kapoor A, Meirs RS, Belgrave R, Engiles J, Van de Walle GR, Divers TJ. Viral testing of 10 cases of Theiler's disease and 37 in-contact horses in the absence of equine biologic product administration: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 258-265.

                


                  Yu Y, Scheel TKH, Luna JM, Chung H, Nishiuchi E, Scull MA, Echeverría N, Ricardo-Lax I, Kapoor A, Lipkin WI, Divers TJ, Antczak DF, Tennant BC, Rice CM. Correction: miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathog. 2018 Sep; 14: e1007303.

                


                  Trivedi S, Murthy S, Sharma H, Hartlage AS, Kumar A, Gadi SV, Simmonds P, Chauhan LV, Scheel TKH, Billerbeck E, Burbelo PD, Rice CM, Lipkin WI, Vandegrift K, Cullen JM, Kapoor A. Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model. Hepatology. 2018 Aug; 68: 435-448.

                


                  Divers TJ, Tennant BC, Kumar A, McDonough S, Cullen J, Bhuva N, Jain K, Chauhan LS, Scheel TKH, Lipkin WI, Laverack M, Trivedi S, Srinivasa S, Beard L, Rice CM, Burbelo PD, Renshaw RW, Dubovi E, Kapoor A. New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product. Emerg Infect Dis. 2018 Feb; 24: 303-310.

View More Publications

Research

Lab(s)

Center for Vaccines and Immunity

View My Publications

Publications

                  Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters. J Virol. 2021 Sep 27; 95: e0059221.

                


                  Tomlinson JE, Wolfisberg R, Fahnøe U, Patel RS, Trivedi S, Kumar A, Sharma H, Nielsen L, McDonough SP, Bukh J, Tennant BC, Kapoor A, Rosenberg BR, Rice CM, Divers TJ, Van de Walle GR, Scheel TKH. Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology. 2021 Sep; 74: 1148-1163.

                


                  Hartlage AS, Kapoor A. Hepatitis C Virus Vaccine Research: Time to Put Up or Shut Up. Viruses. 2021 Aug 12; 13: 

                


                  Erdem G, Kaptsan I, Sharma H, Kumar A, Aylward SC, Kapoor A, Shimamura M. Cerebrospinal Fluid Analysis for Viruses by Metagenomic Next-Generation Sequencing in Pediatric Encephalitis: Not Yet Ready for Prime Time? J Child Neurol. 2021 Apr; 36: 350-356.

                


                  Hartlage AS, Dravid P, Walker CM, Kapoor A. Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats. PLoS Pathog. 2021 Mar; 17: e1009391.

                


                  Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike. Proc Natl Acad Sci U S A. 2021 Mar 23; 118: 

                


                  Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunisation strategies for HCV. Hepatology. 2019 Aug 10;  

                


                  Wolfisberg R, Holmbeck K, Nielsen L, Kapoor A, Rice CM, Bukh J, Scheel TKH. Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells. J Virol. 2019 Jul 10;  

                


                  Vandegrift KJ, Kapoor A. The Ecology of New Constituents of the Tick Virome and Their Relevance to Public Health. Viruses. 2019 Jun 7; 11: 

                


                  Hartlage AS, Murthy S, Kumar A, Trivedi S, Dravid P, Sharma H, Walker CM, Kapoor A. Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection. Nat Commun. 2019 Mar 7; 10: 1113.

                


                  Tomlinson JE, Kapoor A, Kumar A, Tennant BC, Laverack MA, Beard L, Delph K, Davis E, Schott Ii H, Lascola K, Holbrook TC, Johnson P, Taylor SD, McKenzie E, Carter-Arnold J, Setlakwe E, Fultz L, Brakenhoff J, Ruby R, Trivedi S, Van de Walle GR, Renshaw RW, Dubovi EJ, Divers TJ. Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 251-257.

                


                  Tomlinson JE, Tennant BC, Struzyna A, Mrad D, Browne N, Whelchel D, Johnson PJ, Jamieson C, Löhr CV, Bildfell R, McKenzie EC, Laverack M, Renshaw RW, Dubovi E, Kapoor A, Meirs RS, Belgrave R, Engiles J, Van de Walle GR, Divers TJ. Viral testing of 10 cases of Theiler's disease and 37 in-contact horses in the absence of equine biologic product administration: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 258-265.

                


                  Yu Y, Scheel TKH, Luna JM, Chung H, Nishiuchi E, Scull MA, Echeverría N, Ricardo-Lax I, Kapoor A, Lipkin WI, Divers TJ, Antczak DF, Tennant BC, Rice CM. Correction: miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathog. 2018 Sep; 14: e1007303.

                


                  Trivedi S, Murthy S, Sharma H, Hartlage AS, Kumar A, Gadi SV, Simmonds P, Chauhan LV, Scheel TKH, Billerbeck E, Burbelo PD, Rice CM, Lipkin WI, Vandegrift K, Cullen JM, Kapoor A. Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model. Hepatology. 2018 Aug; 68: 435-448.

                


                  Divers TJ, Tennant BC, Kumar A, McDonough S, Cullen J, Bhuva N, Jain K, Chauhan LS, Scheel TKH, Lipkin WI, Laverack M, Trivedi S, Srinivasa S, Beard L, Rice CM, Burbelo PD, Renshaw RW, Dubovi E, Kapoor A. New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product. Emerg Infect Dis. 2018 Feb; 24: 303-310.

View More Publications

Lab(s)

Center for Vaccines and Immunity

View My Publications

Publications

                  Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters. J Virol. 2021 Sep 27; 95: e0059221.

                


                  Tomlinson JE, Wolfisberg R, Fahnøe U, Patel RS, Trivedi S, Kumar A, Sharma H, Nielsen L, McDonough SP, Bukh J, Tennant BC, Kapoor A, Rosenberg BR, Rice CM, Divers TJ, Van de Walle GR, Scheel TKH. Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology. 2021 Sep; 74: 1148-1163.

                


                  Hartlage AS, Kapoor A. Hepatitis C Virus Vaccine Research: Time to Put Up or Shut Up. Viruses. 2021 Aug 12; 13: 

                


                  Erdem G, Kaptsan I, Sharma H, Kumar A, Aylward SC, Kapoor A, Shimamura M. Cerebrospinal Fluid Analysis for Viruses by Metagenomic Next-Generation Sequencing in Pediatric Encephalitis: Not Yet Ready for Prime Time? J Child Neurol. 2021 Apr; 36: 350-356.

                


                  Hartlage AS, Dravid P, Walker CM, Kapoor A. Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats. PLoS Pathog. 2021 Mar; 17: e1009391.

                


                  Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike. Proc Natl Acad Sci U S A. 2021 Mar 23; 118: 

                


                  Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunisation strategies for HCV. Hepatology. 2019 Aug 10;  

                


                  Wolfisberg R, Holmbeck K, Nielsen L, Kapoor A, Rice CM, Bukh J, Scheel TKH. Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells. J Virol. 2019 Jul 10;  

                


                  Vandegrift KJ, Kapoor A. The Ecology of New Constituents of the Tick Virome and Their Relevance to Public Health. Viruses. 2019 Jun 7; 11: 

                


                  Hartlage AS, Murthy S, Kumar A, Trivedi S, Dravid P, Sharma H, Walker CM, Kapoor A. Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection. Nat Commun. 2019 Mar 7; 10: 1113.

                


                  Tomlinson JE, Kapoor A, Kumar A, Tennant BC, Laverack MA, Beard L, Delph K, Davis E, Schott Ii H, Lascola K, Holbrook TC, Johnson P, Taylor SD, McKenzie E, Carter-Arnold J, Setlakwe E, Fultz L, Brakenhoff J, Ruby R, Trivedi S, Van de Walle GR, Renshaw RW, Dubovi EJ, Divers TJ. Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 251-257.

                


                  Tomlinson JE, Tennant BC, Struzyna A, Mrad D, Browne N, Whelchel D, Johnson PJ, Jamieson C, Löhr CV, Bildfell R, McKenzie EC, Laverack M, Renshaw RW, Dubovi E, Kapoor A, Meirs RS, Belgrave R, Engiles J, Van de Walle GR, Divers TJ. Viral testing of 10 cases of Theiler's disease and 37 in-contact horses in the absence of equine biologic product administration: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 258-265.

                


                  Yu Y, Scheel TKH, Luna JM, Chung H, Nishiuchi E, Scull MA, Echeverría N, Ricardo-Lax I, Kapoor A, Lipkin WI, Divers TJ, Antczak DF, Tennant BC, Rice CM. Correction: miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathog. 2018 Sep; 14: e1007303.

                


                  Trivedi S, Murthy S, Sharma H, Hartlage AS, Kumar A, Gadi SV, Simmonds P, Chauhan LV, Scheel TKH, Billerbeck E, Burbelo PD, Rice CM, Lipkin WI, Vandegrift K, Cullen JM, Kapoor A. Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model. Hepatology. 2018 Aug; 68: 435-448.

                


                  Divers TJ, Tennant BC, Kumar A, McDonough S, Cullen J, Bhuva N, Jain K, Chauhan LS, Scheel TKH, Lipkin WI, Laverack M, Trivedi S, Srinivasa S, Beard L, Rice CM, Burbelo PD, Renshaw RW, Dubovi E, Kapoor A. New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product. Emerg Infect Dis. 2018 Feb; 24: 303-310.

View More Publications

Lab(s)

Center for Vaccines and Immunity

Lab(s)

Center for Vaccines and Immunity

Center for Vaccines and Immunity

View My Publications

                Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters. J Virol. 2021 Sep 27; 95: e0059221.



                Tomlinson JE, Wolfisberg R, Fahnøe U, Patel RS, Trivedi S, Kumar A, Sharma H, Nielsen L, McDonough SP, Bukh J, Tennant BC, Kapoor A, Rosenberg BR, Rice CM, Divers TJ, Van de Walle GR, Scheel TKH. Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology. 2021 Sep; 74: 1148-1163.



                Hartlage AS, Kapoor A. Hepatitis C Virus Vaccine Research: Time to Put Up or Shut Up. Viruses. 2021 Aug 12; 13: 



                Erdem G, Kaptsan I, Sharma H, Kumar A, Aylward SC, Kapoor A, Shimamura M. Cerebrospinal Fluid Analysis for Viruses by Metagenomic Next-Generation Sequencing in Pediatric Encephalitis: Not Yet Ready for Prime Time? J Child Neurol. 2021 Apr; 36: 350-356.



                Hartlage AS, Dravid P, Walker CM, Kapoor A. Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats. PLoS Pathog. 2021 Mar; 17: e1009391.



                Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike. Proc Natl Acad Sci U S A. 2021 Mar 23; 118: 



                Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunisation strategies for HCV. Hepatology. 2019 Aug 10;  



                Wolfisberg R, Holmbeck K, Nielsen L, Kapoor A, Rice CM, Bukh J, Scheel TKH. Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells. J Virol. 2019 Jul 10;  



                Vandegrift KJ, Kapoor A. The Ecology of New Constituents of the Tick Virome and Their Relevance to Public Health. Viruses. 2019 Jun 7; 11: 



                Hartlage AS, Murthy S, Kumar A, Trivedi S, Dravid P, Sharma H, Walker CM, Kapoor A. Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection. Nat Commun. 2019 Mar 7; 10: 1113.



                Tomlinson JE, Kapoor A, Kumar A, Tennant BC, Laverack MA, Beard L, Delph K, Davis E, Schott Ii H, Lascola K, Holbrook TC, Johnson P, Taylor SD, McKenzie E, Carter-Arnold J, Setlakwe E, Fultz L, Brakenhoff J, Ruby R, Trivedi S, Van de Walle GR, Renshaw RW, Dubovi EJ, Divers TJ. Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 251-257.



                Tomlinson JE, Tennant BC, Struzyna A, Mrad D, Browne N, Whelchel D, Johnson PJ, Jamieson C, Löhr CV, Bildfell R, McKenzie EC, Laverack M, Renshaw RW, Dubovi E, Kapoor A, Meirs RS, Belgrave R, Engiles J, Van de Walle GR, Divers TJ. Viral testing of 10 cases of Theiler's disease and 37 in-contact horses in the absence of equine biologic product administration: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 258-265.



                Yu Y, Scheel TKH, Luna JM, Chung H, Nishiuchi E, Scull MA, Echeverría N, Ricardo-Lax I, Kapoor A, Lipkin WI, Divers TJ, Antczak DF, Tennant BC, Rice CM. Correction: miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathog. 2018 Sep; 14: e1007303.



                Trivedi S, Murthy S, Sharma H, Hartlage AS, Kumar A, Gadi SV, Simmonds P, Chauhan LV, Scheel TKH, Billerbeck E, Burbelo PD, Rice CM, Lipkin WI, Vandegrift K, Cullen JM, Kapoor A. Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model. Hepatology. 2018 Aug; 68: 435-448.



                Divers TJ, Tennant BC, Kumar A, McDonough S, Cullen J, Bhuva N, Jain K, Chauhan LS, Scheel TKH, Lipkin WI, Laverack M, Trivedi S, Srinivasa S, Beard L, Rice CM, Burbelo PD, Renshaw RW, Dubovi E, Kapoor A. New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product. Emerg Infect Dis. 2018 Feb; 24: 303-310.

View More Publications

Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters. J Virol. 2021 Sep 27; 95: e0059221.
Tomlinson JE, Wolfisberg R, Fahnøe U, Patel RS, Trivedi S, Kumar A, Sharma H, Nielsen L, McDonough SP, Bukh J, Tennant BC, Kapoor A, Rosenberg BR, Rice CM, Divers TJ, Van de Walle GR, Scheel TKH. Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology. 2021 Sep; 74: 1148-1163.
Hartlage AS, Kapoor A. Hepatitis C Virus Vaccine Research: Time to Put Up or Shut Up. Viruses. 2021 Aug 12; 13:
Erdem G, Kaptsan I, Sharma H, Kumar A, Aylward SC, Kapoor A, Shimamura M. Cerebrospinal Fluid Analysis for Viruses by Metagenomic Next-Generation Sequencing in Pediatric Encephalitis: Not Yet Ready for Prime Time? J Child Neurol. 2021 Apr; 36: 350-356.
Hartlage AS, Dravid P, Walker CM, Kapoor A. Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats. PLoS Pathog. 2021 Mar; 17: e1009391.
Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike. Proc Natl Acad Sci U S A. 2021 Mar 23; 118:
Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunisation strategies for HCV. Hepatology. 2019 Aug 10;
Wolfisberg R, Holmbeck K, Nielsen L, Kapoor A, Rice CM, Bukh J, Scheel TKH. Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells. J Virol. 2019 Jul 10;
Vandegrift KJ, Kapoor A. The Ecology of New Constituents of the Tick Virome and Their Relevance to Public Health. Viruses. 2019 Jun 7; 11:
Hartlage AS, Murthy S, Kumar A, Trivedi S, Dravid P, Sharma H, Walker CM, Kapoor A. Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection. Nat Commun. 2019 Mar 7; 10: 1113.
Tomlinson JE, Kapoor A, Kumar A, Tennant BC, Laverack MA, Beard L, Delph K, Davis E, Schott Ii H, Lascola K, Holbrook TC, Johnson P, Taylor SD, McKenzie E, Carter-Arnold J, Setlakwe E, Fultz L, Brakenhoff J, Ruby R, Trivedi S, Van de Walle GR, Renshaw RW, Dubovi EJ, Divers TJ. Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 251-257.
Tomlinson JE, Tennant BC, Struzyna A, Mrad D, Browne N, Whelchel D, Johnson PJ, Jamieson C, Löhr CV, Bildfell R, McKenzie EC, Laverack M, Renshaw RW, Dubovi E, Kapoor A, Meirs RS, Belgrave R, Engiles J, Van de Walle GR, Divers TJ. Viral testing of 10 cases of Theiler’s disease and 37 in-contact horses in the absence of equine biologic product administration: A prospective study (2014-2018). J Vet Intern Med. 2019 Jan; 33: 258-265.
Yu Y, Scheel TKH, Luna JM, Chung H, Nishiuchi E, Scull MA, Echeverría N, Ricardo-Lax I, Kapoor A, Lipkin WI, Divers TJ, Antczak DF, Tennant BC, Rice CM. Correction: miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathog. 2018 Sep; 14: e1007303.
Trivedi S, Murthy S, Sharma H, Hartlage AS, Kumar A, Gadi SV, Simmonds P, Chauhan LV, Scheel TKH, Billerbeck E, Burbelo PD, Rice CM, Lipkin WI, Vandegrift K, Cullen JM, Kapoor A. Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model. Hepatology. 2018 Aug; 68: 435-448.
Divers TJ, Tennant BC, Kumar A, McDonough S, Cullen J, Bhuva N, Jain K, Chauhan LS, Scheel TKH, Lipkin WI, Laverack M, Trivedi S, Srinivasa S, Beard L, Rice CM, Burbelo PD, Renshaw RW, Dubovi E, Kapoor A. New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product. Emerg Infect Dis. 2018 Feb; 24: 303-310.

Biography

Academic and Clinical Areas

Center for Vaccines and Immunity

Principal Investigator

Primary Department

Center for Vaccines and Immunity

Academic and Clinical Areas

Center for Vaccines and Immunity

Principal Investigator

Primary Department

Center for Vaccines and Immunity

Academic and Clinical Areas

Center for Vaccines and Immunity

Principal Investigator

Primary Department

Center for Vaccines and Immunity

Principal Investigator

Primary Department

Center for Vaccines and Immunity

Center for Vaccines and Immunity
Principal Investigator
Primary Department
Center for Vaccines and Immunity

Awards, Honors & Organizations

One of two PNAS papers selected for the section “In this issue” and both articles were accompanied by commentaries
Guest appearance, twice, “This week in virology” (TWiV.tv) – a widely popular science podcast
Work highlighted by New York Times and other science media sites
Two Journal of Virology papers selected for “Spotlight” section
Work featured as cover page of The Journal of Infectious diseases and the ASM Journal mBio
Journal of Virology paper selected, Faculty of 1000 Biology

Professional Experience

2015 - Present Vaccines & Immunity Center, The Research Institute at Nationwide Children’s Hospital,, Principal Investigator

Contact Information

Center for Vaccines and Immunity

Call us at: (614)722-2735

Fax us at: (614)722-3680

                    700 Children's DriveRoom WA4015Columbus, OH 43205 (map)

Contact Information

Center for Vaccines and Immunity

Call us at: (614)722-2735

Fax us at: (614)722-3680

                    700 Children's DriveRoom WA4015Columbus, OH 43205 (map)

Contact Information

Center for Vaccines and Immunity

Call us at: (614)722-2735

Fax us at: (614)722-3680

                    700 Children's DriveRoom WA4015Columbus, OH 43205 (map)

Center for Vaccines and Immunity

Call us at: (614)722-2735

Fax us at: (614)722-3680

                    700 Children's DriveRoom WA4015Columbus, OH 43205 (map)

Call us at: (614)722-2735

Fax us at: (614)722-3680

                    700 Children's DriveRoom WA4015Columbus, OH 43205 (map)

Call us at: (614)722-2735

Fax us at: (614)722-3680

                    700 Children's DriveRoom WA4015Columbus, OH 43205 (map)

Call us at:
(614)722-2735
Fax us at:
(614)722-3680
700 Children’s DriveRoom WA4015Columbus, OH 43205 (map)

Contact Information#

Contact Information