Aaron J Trask

Contact Information

Call us at: (614)355-5760

Fax us at: (614)355-5725

      Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Learn more about Aaron J. Trask

Research

Lab(s)

Center for Cardiovascular Research

Publications

                  Bartlett CW, Bossenbroek J, Ueyama Y, McCallinhart P, Peters OA, Santillan DA, Santillan MK, Trask AJ, Ray WC. Invasive or More Direct Measurements Can Provide an Objective Early-Stopping Ceiling for Training Deep Neural Networks on Non-invasive or Less-Direct Biomedical Data. SN Comput Sci. 2023; 4: 161.

                


                  Tune JD, Goodwill AG, Baker HE, Dick GM, Warne CM, Tucker SM, Essajee SI, Bailey CA, Klasing JA, Russell JJ, McCallinhart PE, Trask AJ, Bender SB. Chronic high-rate pacing induces heart failure with preserved ejection fraction-like phenotype in Ossabaw swine. Basic Res Cardiol. 2022 Oct 12; 117: 50.

                


                  Breikaa RM, Denman K, Ueyama Y, McCallinhart PE, Khan AQ, Agarwal G, Trask AJ, Garg V, Lilly B. Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes. Vascul Pharmacol. 2022 Jul 2; 145: 107087.

                


                  Ogola BO, Abshire CM, Visniauskas B, Kiley JX, Horton AC, Clark GL, Kilanowski-Doroh I, Diaz Z, Bicego AN, McNally AB, Zimmerman MA, Groban L, Trask AJ, Miller KS, Lindsey SH. Sex Differences in Vascular Aging and Impact of GPER Deletion. Am J Physiol Heart Circ Physiol. 2022 Jun 24;  

                


                  Bossenbroek J, Ueyama Y, McCallinhart PE, Bartlett CW, Ray WC, Trask AJ. Improvement of automated analysis of coronary Doppler echocardiograms. Sci Rep. 2022 May 6; 12: 7490.

                


                  Blum KM, Zbinden JC, Ramachandra AB, Lindsey SE, Szafron JM, Reinhardt JW, Heitkemper M, Best CA, Mirhaidari GJM, Chang YC, Ulziibayar A, Kelly J, Shah KV, Drews JD, Zakko J, Miyamoto S, Matsuzaki Y, Iwaki R, Ahmad H, Daulton R, Musgrave D, Wiet MG, Heuer E, Lawson E, Schwarz E, McDermott MR, Krishnamurthy R, Krishnamurthy R, Hor K, Armstrong AK, Boe BA, Berman DP, Trask AJ, Humphrey JD, Marsden AL, Shinoka T, Breuer CK. Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth. Commun Med (Lond). 2022; 2: 3.

                


                  Nordquist EM, Dutta P, Kodigepalli KM, Mattern C, McDermott MR, Trask AJ, LaHaye S, Lindner V, Lincoln J. Tgfß1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. Arterioscler Thromb Vasc Biol. 2021 Dec; 41: 2923-2942.

                


                  Ernzen K, Trask AJ, Peeples ME, Garg V, Zhao MT. Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System. Stem Cell Rev Rep. 2021 Dec; 17: 2107-2119.

                


                  Childers RC, Trask AJ, Liu J, Lucchesi PA, Gooch KJ. Paired Pressure-Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts. J Biomech Eng. 2021 Aug 1; 143: 

                


                  Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Guidelines for the measurement of vascular function and structure in isolated arteries and veins. Am J Physiol Heart Circ Physiol. 2021 Jul 1; 321: H77-H111.

                


                  Wang H, Marrosu E, Brayson D, Wasala NB, Johnson EK, Scott CS, Yue Y, Hau KL, Trask AJ, Froehner SC, Adams ME, Zhang L, Duan D, Montanaro F. Proteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin. Hum Mol Genet. 2021 Jun 26; 30: 1321-1336.

                


                  Goodwill AG, Baker HE, Dick GM, McCallinhart PE, Bailey CA, Brown SM, Man JJ, Tharp DL, Clark HE, Blaettner BS, Jaffe IZ, Bowles DK, Trask AJ, Tune JD, Bender SB. Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in Kv channels. Basic Res Cardiol. 2021 May 20; 116: 35.

                


                  Eddy AC, Trask AJ. Growth differentiation factor-15 and its role in diabetes and cardiovascular disease. Cytokine Growth Factor Rev. 2021 Feb; 57: 11-18.

                


                  McCallinhart PE, Scandling BW, Trask AJ. Coronary remodeling and biomechanics: Are we going with the flow in 2020? Am J Physiol Heart Circ Physiol. 2021 Feb 1; 320: H584-H592.

                


                  McCallinhart PE, Cho Y, Sun Z, Ghadiali S, Meininger GA, Trask AJ. Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle. Am J Physiol Heart Circ Physiol. 2020 Jun 1; 318: H1410-H1419.

                


                  Lilly B, Dammeyer K, Marosis S, McCallinhart PE, Trask AJ, Lowe M, Sawant D. Endothelial cell-induced cytoglobin expression in vascular smooth muscle cells contributes to modulation of nitric oxide. Vascul Pharmacol. 2018 Nov; 110: 7-15.

                


                  Sunyecz IL, McCallinhart PE, Patel KU, McDermott MR, Trask AJ. Defining Coronary Flow Patterns: Comprehensive Automation of Transthoracic Doppler Coronary Blood Flow. Sci Rep. 2018 Nov 22; 8: 17268.

                


                  McCallinhart PE, Sunyecz IL, Trask AJ. Coronary Microvascular Remodeling in Type 2 Diabetes: Synonymous With Early Aging? Front Physiol. 2018; 9: 1463.

View More Publications

Biography

Aaron J. Trask, PhD, FAHA, is a Principal Investigator in the Center for Cardiovascular and Pulmonary Research at Nationwide Children’s Hospital and an Assistant Professor (Tenure Track) in the Department of Pediatrics at The Ohio State University College of Medicine. He trained as a physiologist and pharmacologist at Wake Forest University and completed his postdoctoral training in cardiovascular physiology at Nationwide Children’s Hospital. Dr. Trask’s research focuses on studying processes involved in adverse micro- and macro-vascular remodeling in disease, including early type 2 diabetes and metabolic syndrome.

Academic and Clinical Areas

Center for Cardiovascular Research

Principal Investigator

Awards, Honors & Organizations

Joint Meeting Award, APS-TPS, Dublin, Ireland, 2016 Junior Faculty Citizenship Award, Department of Pediatrics, The Ohio State University College of Medicine, 2015 Elected Fellow (Barbara J. Alexander, PhD, FAHA, Nominator), American Heart Association Council for High Blood Pressure Research, 2014 Invitee/Participant, American Heart Association Scientific Meetings Summit, 2014 Research Recognition Award, Cardiovascular Section, American Physiological Society, 2012 Best Poster Award – Postdoctoral Fellow Category, The Research Institute at Nationwide Children’s Hospital Research Day, 2012 Caroline tum Suden/Frances A. Hellebrandt Professional Opportunity Award, American Physiological Society, 2010 Logo Design Award Winner, American Physiological Society, 2010 Sundberg Memorial Award, WFU Department of Physiology & Pharmacology, 2009 Who’s Who Among Executives and Professionals, Marquis, 2009 Merck New Investigator Award, American Heart Association Council for High Blood Pressure Research, 2008 Hypertension Summer School Travel Award, American Heart Association, 2007 Alumni Travel Award, Wake Forest University Graduate School, 2007 Alumni Travel Award, Wake Forest University Graduate School, 2006 Arts & Sciences Scholarship (2000-2003), Ohio Northern University, 2000 Dean’s Scholarship, Ohio Northern University, 1999 Tiffany Furgason Memorial Scholarship, 1999 Arcanum Alumni Scholarship, 1999 Dean’s List (1999-2003), Ohio Northern University, 1999 Achievement/Leadership Award Scholarship (1999-2003), Ohio Northern University, 1999 Early Career Subcommittee, American Heart Association National Committee on Committees, 2014 - 2015 Member, Microcirculatory Society, 2013 - Present Faculty Representative, Finance and Sponsored Projects Advisory Group, Nationwide Children’s Hospital, 2013 - Present Member, American Association for the Advancement of Science, 2011 - Present Member, American Society for Pharmacology and Experimental Therapeutics Division of Cardiovascular Pharmacology (2009-2012 Public Relations/Communications Committee; 2016-2017: Executive Committee; 2016-2019:, 2009 - Present Founding Member, Nationwide Children’s Hospital Postdoctoral Association, 2009 - 2013 Student Member, Wake Forest University Department of Physiology and Pharmacology Curriculum Committee, 2006 - Present Member, American Heart Association Council on Hypertension (2009-2013: Member, Trainee Advocacy Committee; 2013-2016: Chair, Trainee Advocacy Committee; 2013-2016: Member, Leadership Committee; 2015: Programm, 2005 - Present Member, American Physiological Society (APS), Cardiovascular Section (2009-2012: NIH-NHLBI Liaison Committee; 2012-2015: Awards Committee; 2016-2019: Nominating Committee [Elected]), 2005 - Present Member, Consortium for Southeastern Hypertension Control, 2005 - Present Student Member, Wake Forest University Graduate Student Association, 2004 - 2008 Member, Beta Beta Beta National Biology Honor Society, 2001 - Present Member, Omicron Delta Kappa National Leadership Honor Society, 2001 - Present Chairman, Judicial Board, Ohio Northern University, 2001 - 2003 Chairman, Judicial Committee, Ohio Northern University Student Senate, 2000 - 2003

Professional Experience

2016 - Present Graduate Faculty, Biomedical Engineering Graduate Program, The Ohio State University, Member2016 - Present Department of Pediatrics, The Ohio State University College of Medicine, Assistant Professor (Tenure Track)2016 - Present Department of Physiology and Cell Biology, The Ohio State University College of Medicine, Adjunct Assistant Professor2015 - Present Graduate Faculty, Integrated Biomedical Science Graduate Program, The Ohio State University, Member2015 - Present Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University Wexner Medical Center, Investigator2013 - Present Center for Cardiovascular and Pulmonary Research and The Heart Center, The Research Institute at Nationwide Children’s Hospital, Principal Investigator2013 - 2016 Department of Pediatrics, The Ohio State University College of Medicine, Research Assistant Professor

Contact Information

Call us at: (614)355-5760

Fax us at: (614)355-5725

                    Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Contact Information

Call us at: (614)355-5760

Fax us at: (614)355-5725

      Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Learn more about Aaron J. Trask

Research

Lab(s)

Center for Cardiovascular Research

Publications

                  Bartlett CW, Bossenbroek J, Ueyama Y, McCallinhart P, Peters OA, Santillan DA, Santillan MK, Trask AJ, Ray WC. Invasive or More Direct Measurements Can Provide an Objective Early-Stopping Ceiling for Training Deep Neural Networks on Non-invasive or Less-Direct Biomedical Data. SN Comput Sci. 2023; 4: 161.

                


                  Tune JD, Goodwill AG, Baker HE, Dick GM, Warne CM, Tucker SM, Essajee SI, Bailey CA, Klasing JA, Russell JJ, McCallinhart PE, Trask AJ, Bender SB. Chronic high-rate pacing induces heart failure with preserved ejection fraction-like phenotype in Ossabaw swine. Basic Res Cardiol. 2022 Oct 12; 117: 50.

                


                  Breikaa RM, Denman K, Ueyama Y, McCallinhart PE, Khan AQ, Agarwal G, Trask AJ, Garg V, Lilly B. Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes. Vascul Pharmacol. 2022 Jul 2; 145: 107087.

                


                  Ogola BO, Abshire CM, Visniauskas B, Kiley JX, Horton AC, Clark GL, Kilanowski-Doroh I, Diaz Z, Bicego AN, McNally AB, Zimmerman MA, Groban L, Trask AJ, Miller KS, Lindsey SH. Sex Differences in Vascular Aging and Impact of GPER Deletion. Am J Physiol Heart Circ Physiol. 2022 Jun 24;  

                


                  Bossenbroek J, Ueyama Y, McCallinhart PE, Bartlett CW, Ray WC, Trask AJ. Improvement of automated analysis of coronary Doppler echocardiograms. Sci Rep. 2022 May 6; 12: 7490.

                


                  Blum KM, Zbinden JC, Ramachandra AB, Lindsey SE, Szafron JM, Reinhardt JW, Heitkemper M, Best CA, Mirhaidari GJM, Chang YC, Ulziibayar A, Kelly J, Shah KV, Drews JD, Zakko J, Miyamoto S, Matsuzaki Y, Iwaki R, Ahmad H, Daulton R, Musgrave D, Wiet MG, Heuer E, Lawson E, Schwarz E, McDermott MR, Krishnamurthy R, Krishnamurthy R, Hor K, Armstrong AK, Boe BA, Berman DP, Trask AJ, Humphrey JD, Marsden AL, Shinoka T, Breuer CK. Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth. Commun Med (Lond). 2022; 2: 3.

                


                  Nordquist EM, Dutta P, Kodigepalli KM, Mattern C, McDermott MR, Trask AJ, LaHaye S, Lindner V, Lincoln J. Tgfß1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. Arterioscler Thromb Vasc Biol. 2021 Dec; 41: 2923-2942.

                


                  Ernzen K, Trask AJ, Peeples ME, Garg V, Zhao MT. Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System. Stem Cell Rev Rep. 2021 Dec; 17: 2107-2119.

                


                  Childers RC, Trask AJ, Liu J, Lucchesi PA, Gooch KJ. Paired Pressure-Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts. J Biomech Eng. 2021 Aug 1; 143: 

                


                  Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Guidelines for the measurement of vascular function and structure in isolated arteries and veins. Am J Physiol Heart Circ Physiol. 2021 Jul 1; 321: H77-H111.

                


                  Wang H, Marrosu E, Brayson D, Wasala NB, Johnson EK, Scott CS, Yue Y, Hau KL, Trask AJ, Froehner SC, Adams ME, Zhang L, Duan D, Montanaro F. Proteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin. Hum Mol Genet. 2021 Jun 26; 30: 1321-1336.

                


                  Goodwill AG, Baker HE, Dick GM, McCallinhart PE, Bailey CA, Brown SM, Man JJ, Tharp DL, Clark HE, Blaettner BS, Jaffe IZ, Bowles DK, Trask AJ, Tune JD, Bender SB. Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in Kv channels. Basic Res Cardiol. 2021 May 20; 116: 35.

                


                  Eddy AC, Trask AJ. Growth differentiation factor-15 and its role in diabetes and cardiovascular disease. Cytokine Growth Factor Rev. 2021 Feb; 57: 11-18.

                


                  McCallinhart PE, Scandling BW, Trask AJ. Coronary remodeling and biomechanics: Are we going with the flow in 2020? Am J Physiol Heart Circ Physiol. 2021 Feb 1; 320: H584-H592.

                


                  McCallinhart PE, Cho Y, Sun Z, Ghadiali S, Meininger GA, Trask AJ. Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle. Am J Physiol Heart Circ Physiol. 2020 Jun 1; 318: H1410-H1419.

                


                  Lilly B, Dammeyer K, Marosis S, McCallinhart PE, Trask AJ, Lowe M, Sawant D. Endothelial cell-induced cytoglobin expression in vascular smooth muscle cells contributes to modulation of nitric oxide. Vascul Pharmacol. 2018 Nov; 110: 7-15.

                


                  Sunyecz IL, McCallinhart PE, Patel KU, McDermott MR, Trask AJ. Defining Coronary Flow Patterns: Comprehensive Automation of Transthoracic Doppler Coronary Blood Flow. Sci Rep. 2018 Nov 22; 8: 17268.

                


                  McCallinhart PE, Sunyecz IL, Trask AJ. Coronary Microvascular Remodeling in Type 2 Diabetes: Synonymous With Early Aging? Front Physiol. 2018; 9: 1463.

View More Publications

Biography

Academic and Clinical Areas

Center for Cardiovascular Research

Principal Investigator

Awards, Honors & Organizations

Professional Experience

Contact Information

Call us at: (614)355-5760

Fax us at: (614)355-5725

                    Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Contact Information

Call us at: (614)355-5760

Fax us at: (614)355-5725

      Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Learn more about Aaron J. Trask

Contact Information

Call us at:
(614)355-5760
Fax us at:
(614)355-5725
Abigail Wexner Research InstituteWB4135, 700 Children’s Dr Columbus, 43205 (map)

Learn more about Aaron J. Trask

Research

Lab(s)

Center for Cardiovascular Research

Publications

                  Bartlett CW, Bossenbroek J, Ueyama Y, McCallinhart P, Peters OA, Santillan DA, Santillan MK, Trask AJ, Ray WC. Invasive or More Direct Measurements Can Provide an Objective Early-Stopping Ceiling for Training Deep Neural Networks on Non-invasive or Less-Direct Biomedical Data. SN Comput Sci. 2023; 4: 161.

                


                  Tune JD, Goodwill AG, Baker HE, Dick GM, Warne CM, Tucker SM, Essajee SI, Bailey CA, Klasing JA, Russell JJ, McCallinhart PE, Trask AJ, Bender SB. Chronic high-rate pacing induces heart failure with preserved ejection fraction-like phenotype in Ossabaw swine. Basic Res Cardiol. 2022 Oct 12; 117: 50.

                


                  Breikaa RM, Denman K, Ueyama Y, McCallinhart PE, Khan AQ, Agarwal G, Trask AJ, Garg V, Lilly B. Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes. Vascul Pharmacol. 2022 Jul 2; 145: 107087.

                


                  Ogola BO, Abshire CM, Visniauskas B, Kiley JX, Horton AC, Clark GL, Kilanowski-Doroh I, Diaz Z, Bicego AN, McNally AB, Zimmerman MA, Groban L, Trask AJ, Miller KS, Lindsey SH. Sex Differences in Vascular Aging and Impact of GPER Deletion. Am J Physiol Heart Circ Physiol. 2022 Jun 24;  

                


                  Bossenbroek J, Ueyama Y, McCallinhart PE, Bartlett CW, Ray WC, Trask AJ. Improvement of automated analysis of coronary Doppler echocardiograms. Sci Rep. 2022 May 6; 12: 7490.

                


                  Blum KM, Zbinden JC, Ramachandra AB, Lindsey SE, Szafron JM, Reinhardt JW, Heitkemper M, Best CA, Mirhaidari GJM, Chang YC, Ulziibayar A, Kelly J, Shah KV, Drews JD, Zakko J, Miyamoto S, Matsuzaki Y, Iwaki R, Ahmad H, Daulton R, Musgrave D, Wiet MG, Heuer E, Lawson E, Schwarz E, McDermott MR, Krishnamurthy R, Krishnamurthy R, Hor K, Armstrong AK, Boe BA, Berman DP, Trask AJ, Humphrey JD, Marsden AL, Shinoka T, Breuer CK. Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth. Commun Med (Lond). 2022; 2: 3.

                


                  Nordquist EM, Dutta P, Kodigepalli KM, Mattern C, McDermott MR, Trask AJ, LaHaye S, Lindner V, Lincoln J. Tgfß1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. Arterioscler Thromb Vasc Biol. 2021 Dec; 41: 2923-2942.

                


                  Ernzen K, Trask AJ, Peeples ME, Garg V, Zhao MT. Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System. Stem Cell Rev Rep. 2021 Dec; 17: 2107-2119.

                


                  Childers RC, Trask AJ, Liu J, Lucchesi PA, Gooch KJ. Paired Pressure-Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts. J Biomech Eng. 2021 Aug 1; 143: 

                


                  Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Guidelines for the measurement of vascular function and structure in isolated arteries and veins. Am J Physiol Heart Circ Physiol. 2021 Jul 1; 321: H77-H111.

                


                  Wang H, Marrosu E, Brayson D, Wasala NB, Johnson EK, Scott CS, Yue Y, Hau KL, Trask AJ, Froehner SC, Adams ME, Zhang L, Duan D, Montanaro F. Proteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin. Hum Mol Genet. 2021 Jun 26; 30: 1321-1336.

                


                  Goodwill AG, Baker HE, Dick GM, McCallinhart PE, Bailey CA, Brown SM, Man JJ, Tharp DL, Clark HE, Blaettner BS, Jaffe IZ, Bowles DK, Trask AJ, Tune JD, Bender SB. Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in Kv channels. Basic Res Cardiol. 2021 May 20; 116: 35.

                


                  Eddy AC, Trask AJ. Growth differentiation factor-15 and its role in diabetes and cardiovascular disease. Cytokine Growth Factor Rev. 2021 Feb; 57: 11-18.

                


                  McCallinhart PE, Scandling BW, Trask AJ. Coronary remodeling and biomechanics: Are we going with the flow in 2020? Am J Physiol Heart Circ Physiol. 2021 Feb 1; 320: H584-H592.

                


                  McCallinhart PE, Cho Y, Sun Z, Ghadiali S, Meininger GA, Trask AJ. Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle. Am J Physiol Heart Circ Physiol. 2020 Jun 1; 318: H1410-H1419.

                


                  Lilly B, Dammeyer K, Marosis S, McCallinhart PE, Trask AJ, Lowe M, Sawant D. Endothelial cell-induced cytoglobin expression in vascular smooth muscle cells contributes to modulation of nitric oxide. Vascul Pharmacol. 2018 Nov; 110: 7-15.

                


                  Sunyecz IL, McCallinhart PE, Patel KU, McDermott MR, Trask AJ. Defining Coronary Flow Patterns: Comprehensive Automation of Transthoracic Doppler Coronary Blood Flow. Sci Rep. 2018 Nov 22; 8: 17268.

                


                  McCallinhart PE, Sunyecz IL, Trask AJ. Coronary Microvascular Remodeling in Type 2 Diabetes: Synonymous With Early Aging? Front Physiol. 2018; 9: 1463.

View More Publications

Research

Lab(s)

Center for Cardiovascular Research

Publications

                  Bartlett CW, Bossenbroek J, Ueyama Y, McCallinhart P, Peters OA, Santillan DA, Santillan MK, Trask AJ, Ray WC. Invasive or More Direct Measurements Can Provide an Objective Early-Stopping Ceiling for Training Deep Neural Networks on Non-invasive or Less-Direct Biomedical Data. SN Comput Sci. 2023; 4: 161.

                


                  Tune JD, Goodwill AG, Baker HE, Dick GM, Warne CM, Tucker SM, Essajee SI, Bailey CA, Klasing JA, Russell JJ, McCallinhart PE, Trask AJ, Bender SB. Chronic high-rate pacing induces heart failure with preserved ejection fraction-like phenotype in Ossabaw swine. Basic Res Cardiol. 2022 Oct 12; 117: 50.

                


                  Breikaa RM, Denman K, Ueyama Y, McCallinhart PE, Khan AQ, Agarwal G, Trask AJ, Garg V, Lilly B. Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes. Vascul Pharmacol. 2022 Jul 2; 145: 107087.

                


                  Ogola BO, Abshire CM, Visniauskas B, Kiley JX, Horton AC, Clark GL, Kilanowski-Doroh I, Diaz Z, Bicego AN, McNally AB, Zimmerman MA, Groban L, Trask AJ, Miller KS, Lindsey SH. Sex Differences in Vascular Aging and Impact of GPER Deletion. Am J Physiol Heart Circ Physiol. 2022 Jun 24;  

                


                  Bossenbroek J, Ueyama Y, McCallinhart PE, Bartlett CW, Ray WC, Trask AJ. Improvement of automated analysis of coronary Doppler echocardiograms. Sci Rep. 2022 May 6; 12: 7490.

                


                  Blum KM, Zbinden JC, Ramachandra AB, Lindsey SE, Szafron JM, Reinhardt JW, Heitkemper M, Best CA, Mirhaidari GJM, Chang YC, Ulziibayar A, Kelly J, Shah KV, Drews JD, Zakko J, Miyamoto S, Matsuzaki Y, Iwaki R, Ahmad H, Daulton R, Musgrave D, Wiet MG, Heuer E, Lawson E, Schwarz E, McDermott MR, Krishnamurthy R, Krishnamurthy R, Hor K, Armstrong AK, Boe BA, Berman DP, Trask AJ, Humphrey JD, Marsden AL, Shinoka T, Breuer CK. Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth. Commun Med (Lond). 2022; 2: 3.

                


                  Nordquist EM, Dutta P, Kodigepalli KM, Mattern C, McDermott MR, Trask AJ, LaHaye S, Lindner V, Lincoln J. Tgfß1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. Arterioscler Thromb Vasc Biol. 2021 Dec; 41: 2923-2942.

                


                  Ernzen K, Trask AJ, Peeples ME, Garg V, Zhao MT. Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System. Stem Cell Rev Rep. 2021 Dec; 17: 2107-2119.

                


                  Childers RC, Trask AJ, Liu J, Lucchesi PA, Gooch KJ. Paired Pressure-Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts. J Biomech Eng. 2021 Aug 1; 143: 

                


                  Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Guidelines for the measurement of vascular function and structure in isolated arteries and veins. Am J Physiol Heart Circ Physiol. 2021 Jul 1; 321: H77-H111.

                


                  Wang H, Marrosu E, Brayson D, Wasala NB, Johnson EK, Scott CS, Yue Y, Hau KL, Trask AJ, Froehner SC, Adams ME, Zhang L, Duan D, Montanaro F. Proteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin. Hum Mol Genet. 2021 Jun 26; 30: 1321-1336.

                


                  Goodwill AG, Baker HE, Dick GM, McCallinhart PE, Bailey CA, Brown SM, Man JJ, Tharp DL, Clark HE, Blaettner BS, Jaffe IZ, Bowles DK, Trask AJ, Tune JD, Bender SB. Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in Kv channels. Basic Res Cardiol. 2021 May 20; 116: 35.

                


                  Eddy AC, Trask AJ. Growth differentiation factor-15 and its role in diabetes and cardiovascular disease. Cytokine Growth Factor Rev. 2021 Feb; 57: 11-18.

                


                  McCallinhart PE, Scandling BW, Trask AJ. Coronary remodeling and biomechanics: Are we going with the flow in 2020? Am J Physiol Heart Circ Physiol. 2021 Feb 1; 320: H584-H592.

                


                  McCallinhart PE, Cho Y, Sun Z, Ghadiali S, Meininger GA, Trask AJ. Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle. Am J Physiol Heart Circ Physiol. 2020 Jun 1; 318: H1410-H1419.

                


                  Lilly B, Dammeyer K, Marosis S, McCallinhart PE, Trask AJ, Lowe M, Sawant D. Endothelial cell-induced cytoglobin expression in vascular smooth muscle cells contributes to modulation of nitric oxide. Vascul Pharmacol. 2018 Nov; 110: 7-15.

                


                  Sunyecz IL, McCallinhart PE, Patel KU, McDermott MR, Trask AJ. Defining Coronary Flow Patterns: Comprehensive Automation of Transthoracic Doppler Coronary Blood Flow. Sci Rep. 2018 Nov 22; 8: 17268.

                


                  McCallinhart PE, Sunyecz IL, Trask AJ. Coronary Microvascular Remodeling in Type 2 Diabetes: Synonymous With Early Aging? Front Physiol. 2018; 9: 1463.

View More Publications

Research

Lab(s)

Center for Cardiovascular Research

Publications

                  Bartlett CW, Bossenbroek J, Ueyama Y, McCallinhart P, Peters OA, Santillan DA, Santillan MK, Trask AJ, Ray WC. Invasive or More Direct Measurements Can Provide an Objective Early-Stopping Ceiling for Training Deep Neural Networks on Non-invasive or Less-Direct Biomedical Data. SN Comput Sci. 2023; 4: 161.

                


                  Tune JD, Goodwill AG, Baker HE, Dick GM, Warne CM, Tucker SM, Essajee SI, Bailey CA, Klasing JA, Russell JJ, McCallinhart PE, Trask AJ, Bender SB. Chronic high-rate pacing induces heart failure with preserved ejection fraction-like phenotype in Ossabaw swine. Basic Res Cardiol. 2022 Oct 12; 117: 50.

                


                  Breikaa RM, Denman K, Ueyama Y, McCallinhart PE, Khan AQ, Agarwal G, Trask AJ, Garg V, Lilly B. Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes. Vascul Pharmacol. 2022 Jul 2; 145: 107087.

                


                  Ogola BO, Abshire CM, Visniauskas B, Kiley JX, Horton AC, Clark GL, Kilanowski-Doroh I, Diaz Z, Bicego AN, McNally AB, Zimmerman MA, Groban L, Trask AJ, Miller KS, Lindsey SH. Sex Differences in Vascular Aging and Impact of GPER Deletion. Am J Physiol Heart Circ Physiol. 2022 Jun 24;  

                


                  Bossenbroek J, Ueyama Y, McCallinhart PE, Bartlett CW, Ray WC, Trask AJ. Improvement of automated analysis of coronary Doppler echocardiograms. Sci Rep. 2022 May 6; 12: 7490.

                


                  Blum KM, Zbinden JC, Ramachandra AB, Lindsey SE, Szafron JM, Reinhardt JW, Heitkemper M, Best CA, Mirhaidari GJM, Chang YC, Ulziibayar A, Kelly J, Shah KV, Drews JD, Zakko J, Miyamoto S, Matsuzaki Y, Iwaki R, Ahmad H, Daulton R, Musgrave D, Wiet MG, Heuer E, Lawson E, Schwarz E, McDermott MR, Krishnamurthy R, Krishnamurthy R, Hor K, Armstrong AK, Boe BA, Berman DP, Trask AJ, Humphrey JD, Marsden AL, Shinoka T, Breuer CK. Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth. Commun Med (Lond). 2022; 2: 3.

                


                  Nordquist EM, Dutta P, Kodigepalli KM, Mattern C, McDermott MR, Trask AJ, LaHaye S, Lindner V, Lincoln J. Tgfß1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. Arterioscler Thromb Vasc Biol. 2021 Dec; 41: 2923-2942.

                


                  Ernzen K, Trask AJ, Peeples ME, Garg V, Zhao MT. Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System. Stem Cell Rev Rep. 2021 Dec; 17: 2107-2119.

                


                  Childers RC, Trask AJ, Liu J, Lucchesi PA, Gooch KJ. Paired Pressure-Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts. J Biomech Eng. 2021 Aug 1; 143: 

                


                  Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Guidelines for the measurement of vascular function and structure in isolated arteries and veins. Am J Physiol Heart Circ Physiol. 2021 Jul 1; 321: H77-H111.

                


                  Wang H, Marrosu E, Brayson D, Wasala NB, Johnson EK, Scott CS, Yue Y, Hau KL, Trask AJ, Froehner SC, Adams ME, Zhang L, Duan D, Montanaro F. Proteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin. Hum Mol Genet. 2021 Jun 26; 30: 1321-1336.

                


                  Goodwill AG, Baker HE, Dick GM, McCallinhart PE, Bailey CA, Brown SM, Man JJ, Tharp DL, Clark HE, Blaettner BS, Jaffe IZ, Bowles DK, Trask AJ, Tune JD, Bender SB. Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in Kv channels. Basic Res Cardiol. 2021 May 20; 116: 35.

                


                  Eddy AC, Trask AJ. Growth differentiation factor-15 and its role in diabetes and cardiovascular disease. Cytokine Growth Factor Rev. 2021 Feb; 57: 11-18.

                


                  McCallinhart PE, Scandling BW, Trask AJ. Coronary remodeling and biomechanics: Are we going with the flow in 2020? Am J Physiol Heart Circ Physiol. 2021 Feb 1; 320: H584-H592.

                


                  McCallinhart PE, Cho Y, Sun Z, Ghadiali S, Meininger GA, Trask AJ. Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle. Am J Physiol Heart Circ Physiol. 2020 Jun 1; 318: H1410-H1419.

                


                  Lilly B, Dammeyer K, Marosis S, McCallinhart PE, Trask AJ, Lowe M, Sawant D. Endothelial cell-induced cytoglobin expression in vascular smooth muscle cells contributes to modulation of nitric oxide. Vascul Pharmacol. 2018 Nov; 110: 7-15.

                


                  Sunyecz IL, McCallinhart PE, Patel KU, McDermott MR, Trask AJ. Defining Coronary Flow Patterns: Comprehensive Automation of Transthoracic Doppler Coronary Blood Flow. Sci Rep. 2018 Nov 22; 8: 17268.

                


                  McCallinhart PE, Sunyecz IL, Trask AJ. Coronary Microvascular Remodeling in Type 2 Diabetes: Synonymous With Early Aging? Front Physiol. 2018; 9: 1463.

View More Publications

Lab(s)

Center for Cardiovascular Research

Publications

                  Bartlett CW, Bossenbroek J, Ueyama Y, McCallinhart P, Peters OA, Santillan DA, Santillan MK, Trask AJ, Ray WC. Invasive or More Direct Measurements Can Provide an Objective Early-Stopping Ceiling for Training Deep Neural Networks on Non-invasive or Less-Direct Biomedical Data. SN Comput Sci. 2023; 4: 161.

                


                  Tune JD, Goodwill AG, Baker HE, Dick GM, Warne CM, Tucker SM, Essajee SI, Bailey CA, Klasing JA, Russell JJ, McCallinhart PE, Trask AJ, Bender SB. Chronic high-rate pacing induces heart failure with preserved ejection fraction-like phenotype in Ossabaw swine. Basic Res Cardiol. 2022 Oct 12; 117: 50.

                


                  Breikaa RM, Denman K, Ueyama Y, McCallinhart PE, Khan AQ, Agarwal G, Trask AJ, Garg V, Lilly B. Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes. Vascul Pharmacol. 2022 Jul 2; 145: 107087.

                


                  Ogola BO, Abshire CM, Visniauskas B, Kiley JX, Horton AC, Clark GL, Kilanowski-Doroh I, Diaz Z, Bicego AN, McNally AB, Zimmerman MA, Groban L, Trask AJ, Miller KS, Lindsey SH. Sex Differences in Vascular Aging and Impact of GPER Deletion. Am J Physiol Heart Circ Physiol. 2022 Jun 24;  

                


                  Bossenbroek J, Ueyama Y, McCallinhart PE, Bartlett CW, Ray WC, Trask AJ. Improvement of automated analysis of coronary Doppler echocardiograms. Sci Rep. 2022 May 6; 12: 7490.

                


                  Blum KM, Zbinden JC, Ramachandra AB, Lindsey SE, Szafron JM, Reinhardt JW, Heitkemper M, Best CA, Mirhaidari GJM, Chang YC, Ulziibayar A, Kelly J, Shah KV, Drews JD, Zakko J, Miyamoto S, Matsuzaki Y, Iwaki R, Ahmad H, Daulton R, Musgrave D, Wiet MG, Heuer E, Lawson E, Schwarz E, McDermott MR, Krishnamurthy R, Krishnamurthy R, Hor K, Armstrong AK, Boe BA, Berman DP, Trask AJ, Humphrey JD, Marsden AL, Shinoka T, Breuer CK. Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth. Commun Med (Lond). 2022; 2: 3.

                


                  Nordquist EM, Dutta P, Kodigepalli KM, Mattern C, McDermott MR, Trask AJ, LaHaye S, Lindner V, Lincoln J. Tgfß1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. Arterioscler Thromb Vasc Biol. 2021 Dec; 41: 2923-2942.

                


                  Ernzen K, Trask AJ, Peeples ME, Garg V, Zhao MT. Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System. Stem Cell Rev Rep. 2021 Dec; 17: 2107-2119.

                


                  Childers RC, Trask AJ, Liu J, Lucchesi PA, Gooch KJ. Paired Pressure-Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts. J Biomech Eng. 2021 Aug 1; 143: 

                


                  Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Guidelines for the measurement of vascular function and structure in isolated arteries and veins. Am J Physiol Heart Circ Physiol. 2021 Jul 1; 321: H77-H111.

                


                  Wang H, Marrosu E, Brayson D, Wasala NB, Johnson EK, Scott CS, Yue Y, Hau KL, Trask AJ, Froehner SC, Adams ME, Zhang L, Duan D, Montanaro F. Proteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin. Hum Mol Genet. 2021 Jun 26; 30: 1321-1336.

                


                  Goodwill AG, Baker HE, Dick GM, McCallinhart PE, Bailey CA, Brown SM, Man JJ, Tharp DL, Clark HE, Blaettner BS, Jaffe IZ, Bowles DK, Trask AJ, Tune JD, Bender SB. Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in Kv channels. Basic Res Cardiol. 2021 May 20; 116: 35.

                


                  Eddy AC, Trask AJ. Growth differentiation factor-15 and its role in diabetes and cardiovascular disease. Cytokine Growth Factor Rev. 2021 Feb; 57: 11-18.

                


                  McCallinhart PE, Scandling BW, Trask AJ. Coronary remodeling and biomechanics: Are we going with the flow in 2020? Am J Physiol Heart Circ Physiol. 2021 Feb 1; 320: H584-H592.

                


                  McCallinhart PE, Cho Y, Sun Z, Ghadiali S, Meininger GA, Trask AJ. Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle. Am J Physiol Heart Circ Physiol. 2020 Jun 1; 318: H1410-H1419.

                


                  Lilly B, Dammeyer K, Marosis S, McCallinhart PE, Trask AJ, Lowe M, Sawant D. Endothelial cell-induced cytoglobin expression in vascular smooth muscle cells contributes to modulation of nitric oxide. Vascul Pharmacol. 2018 Nov; 110: 7-15.

                


                  Sunyecz IL, McCallinhart PE, Patel KU, McDermott MR, Trask AJ. Defining Coronary Flow Patterns: Comprehensive Automation of Transthoracic Doppler Coronary Blood Flow. Sci Rep. 2018 Nov 22; 8: 17268.

                


                  McCallinhart PE, Sunyecz IL, Trask AJ. Coronary Microvascular Remodeling in Type 2 Diabetes: Synonymous With Early Aging? Front Physiol. 2018; 9: 1463.

View More Publications

Lab(s)

Center for Cardiovascular Research

                  Bartlett CW, Bossenbroek J, Ueyama Y, McCallinhart P, Peters OA, Santillan DA, Santillan MK, Trask AJ, Ray WC. Invasive or More Direct Measurements Can Provide an Objective Early-Stopping Ceiling for Training Deep Neural Networks on Non-invasive or Less-Direct Biomedical Data. SN Comput Sci. 2023; 4: 161.

                


                  Tune JD, Goodwill AG, Baker HE, Dick GM, Warne CM, Tucker SM, Essajee SI, Bailey CA, Klasing JA, Russell JJ, McCallinhart PE, Trask AJ, Bender SB. Chronic high-rate pacing induces heart failure with preserved ejection fraction-like phenotype in Ossabaw swine. Basic Res Cardiol. 2022 Oct 12; 117: 50.

                


                  Breikaa RM, Denman K, Ueyama Y, McCallinhart PE, Khan AQ, Agarwal G, Trask AJ, Garg V, Lilly B. Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes. Vascul Pharmacol. 2022 Jul 2; 145: 107087.

                


                  Ogola BO, Abshire CM, Visniauskas B, Kiley JX, Horton AC, Clark GL, Kilanowski-Doroh I, Diaz Z, Bicego AN, McNally AB, Zimmerman MA, Groban L, Trask AJ, Miller KS, Lindsey SH. Sex Differences in Vascular Aging and Impact of GPER Deletion. Am J Physiol Heart Circ Physiol. 2022 Jun 24;  

                


                  Bossenbroek J, Ueyama Y, McCallinhart PE, Bartlett CW, Ray WC, Trask AJ. Improvement of automated analysis of coronary Doppler echocardiograms. Sci Rep. 2022 May 6; 12: 7490.

                


                  Blum KM, Zbinden JC, Ramachandra AB, Lindsey SE, Szafron JM, Reinhardt JW, Heitkemper M, Best CA, Mirhaidari GJM, Chang YC, Ulziibayar A, Kelly J, Shah KV, Drews JD, Zakko J, Miyamoto S, Matsuzaki Y, Iwaki R, Ahmad H, Daulton R, Musgrave D, Wiet MG, Heuer E, Lawson E, Schwarz E, McDermott MR, Krishnamurthy R, Krishnamurthy R, Hor K, Armstrong AK, Boe BA, Berman DP, Trask AJ, Humphrey JD, Marsden AL, Shinoka T, Breuer CK. Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth. Commun Med (Lond). 2022; 2: 3.

                


                  Nordquist EM, Dutta P, Kodigepalli KM, Mattern C, McDermott MR, Trask AJ, LaHaye S, Lindner V, Lincoln J. Tgfß1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. Arterioscler Thromb Vasc Biol. 2021 Dec; 41: 2923-2942.

                


                  Ernzen K, Trask AJ, Peeples ME, Garg V, Zhao MT. Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System. Stem Cell Rev Rep. 2021 Dec; 17: 2107-2119.

                


                  Childers RC, Trask AJ, Liu J, Lucchesi PA, Gooch KJ. Paired Pressure-Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts. J Biomech Eng. 2021 Aug 1; 143: 

                


                  Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Guidelines for the measurement of vascular function and structure in isolated arteries and veins. Am J Physiol Heart Circ Physiol. 2021 Jul 1; 321: H77-H111.

                


                  Wang H, Marrosu E, Brayson D, Wasala NB, Johnson EK, Scott CS, Yue Y, Hau KL, Trask AJ, Froehner SC, Adams ME, Zhang L, Duan D, Montanaro F. Proteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin. Hum Mol Genet. 2021 Jun 26; 30: 1321-1336.

                


                  Goodwill AG, Baker HE, Dick GM, McCallinhart PE, Bailey CA, Brown SM, Man JJ, Tharp DL, Clark HE, Blaettner BS, Jaffe IZ, Bowles DK, Trask AJ, Tune JD, Bender SB. Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in Kv channels. Basic Res Cardiol. 2021 May 20; 116: 35.

                


                  Eddy AC, Trask AJ. Growth differentiation factor-15 and its role in diabetes and cardiovascular disease. Cytokine Growth Factor Rev. 2021 Feb; 57: 11-18.

                


                  McCallinhart PE, Scandling BW, Trask AJ. Coronary remodeling and biomechanics: Are we going with the flow in 2020? Am J Physiol Heart Circ Physiol. 2021 Feb 1; 320: H584-H592.

                


                  McCallinhart PE, Cho Y, Sun Z, Ghadiali S, Meininger GA, Trask AJ. Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle. Am J Physiol Heart Circ Physiol. 2020 Jun 1; 318: H1410-H1419.

                


                  Lilly B, Dammeyer K, Marosis S, McCallinhart PE, Trask AJ, Lowe M, Sawant D. Endothelial cell-induced cytoglobin expression in vascular smooth muscle cells contributes to modulation of nitric oxide. Vascul Pharmacol. 2018 Nov; 110: 7-15.

                


                  Sunyecz IL, McCallinhart PE, Patel KU, McDermott MR, Trask AJ. Defining Coronary Flow Patterns: Comprehensive Automation of Transthoracic Doppler Coronary Blood Flow. Sci Rep. 2018 Nov 22; 8: 17268.

                


                  McCallinhart PE, Sunyecz IL, Trask AJ. Coronary Microvascular Remodeling in Type 2 Diabetes: Synonymous With Early Aging? Front Physiol. 2018; 9: 1463.

View More Publications

Lab(s)

Center for Cardiovascular Research

Center for Cardiovascular Research
Bartlett CW, Bossenbroek J, Ueyama Y, McCallinhart P, Peters OA, Santillan DA, Santillan MK, Trask AJ, Ray WC. Invasive or More Direct Measurements Can Provide an Objective Early-Stopping Ceiling for Training Deep Neural Networks on Non-invasive or Less-Direct Biomedical Data. SN Comput Sci. 2023; 4: 161.
Tune JD, Goodwill AG, Baker HE, Dick GM, Warne CM, Tucker SM, Essajee SI, Bailey CA, Klasing JA, Russell JJ, McCallinhart PE, Trask AJ, Bender SB. Chronic high-rate pacing induces heart failure with preserved ejection fraction-like phenotype in Ossabaw swine. Basic Res Cardiol. 2022 Oct 12; 117: 50.
Breikaa RM, Denman K, Ueyama Y, McCallinhart PE, Khan AQ, Agarwal G, Trask AJ, Garg V, Lilly B. Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes. Vascul Pharmacol. 2022 Jul 2; 145: 107087.
Ogola BO, Abshire CM, Visniauskas B, Kiley JX, Horton AC, Clark GL, Kilanowski-Doroh I, Diaz Z, Bicego AN, McNally AB, Zimmerman MA, Groban L, Trask AJ, Miller KS, Lindsey SH. Sex Differences in Vascular Aging and Impact of GPER Deletion. Am J Physiol Heart Circ Physiol. 2022 Jun 24;
Bossenbroek J, Ueyama Y, McCallinhart PE, Bartlett CW, Ray WC, Trask AJ. Improvement of automated analysis of coronary Doppler echocardiograms. Sci Rep. 2022 May 6; 12: 7490.
Blum KM, Zbinden JC, Ramachandra AB, Lindsey SE, Szafron JM, Reinhardt JW, Heitkemper M, Best CA, Mirhaidari GJM, Chang YC, Ulziibayar A, Kelly J, Shah KV, Drews JD, Zakko J, Miyamoto S, Matsuzaki Y, Iwaki R, Ahmad H, Daulton R, Musgrave D, Wiet MG, Heuer E, Lawson E, Schwarz E, McDermott MR, Krishnamurthy R, Krishnamurthy R, Hor K, Armstrong AK, Boe BA, Berman DP, Trask AJ, Humphrey JD, Marsden AL, Shinoka T, Breuer CK. Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth. Commun Med (Lond). 2022; 2: 3.
Nordquist EM, Dutta P, Kodigepalli KM, Mattern C, McDermott MR, Trask AJ, LaHaye S, Lindner V, Lincoln J. Tgfß1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. Arterioscler Thromb Vasc Biol. 2021 Dec; 41: 2923-2942.
Ernzen K, Trask AJ, Peeples ME, Garg V, Zhao MT. Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System. Stem Cell Rev Rep. 2021 Dec; 17: 2107-2119.
Childers RC, Trask AJ, Liu J, Lucchesi PA, Gooch KJ. Paired Pressure-Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts. J Biomech Eng. 2021 Aug 1; 143:
Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Guidelines for the measurement of vascular function and structure in isolated arteries and veins. Am J Physiol Heart Circ Physiol. 2021 Jul 1; 321: H77-H111.
Wang H, Marrosu E, Brayson D, Wasala NB, Johnson EK, Scott CS, Yue Y, Hau KL, Trask AJ, Froehner SC, Adams ME, Zhang L, Duan D, Montanaro F. Proteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin. Hum Mol Genet. 2021 Jun 26; 30: 1321-1336.
Goodwill AG, Baker HE, Dick GM, McCallinhart PE, Bailey CA, Brown SM, Man JJ, Tharp DL, Clark HE, Blaettner BS, Jaffe IZ, Bowles DK, Trask AJ, Tune JD, Bender SB. Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in Kv channels. Basic Res Cardiol. 2021 May 20; 116: 35.
Eddy AC, Trask AJ. Growth differentiation factor-15 and its role in diabetes and cardiovascular disease. Cytokine Growth Factor Rev. 2021 Feb; 57: 11-18.
McCallinhart PE, Scandling BW, Trask AJ. Coronary remodeling and biomechanics: Are we going with the flow in 2020? Am J Physiol Heart Circ Physiol. 2021 Feb 1; 320: H584-H592.
McCallinhart PE, Cho Y, Sun Z, Ghadiali S, Meininger GA, Trask AJ. Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle. Am J Physiol Heart Circ Physiol. 2020 Jun 1; 318: H1410-H1419.
Lilly B, Dammeyer K, Marosis S, McCallinhart PE, Trask AJ, Lowe M, Sawant D. Endothelial cell-induced cytoglobin expression in vascular smooth muscle cells contributes to modulation of nitric oxide. Vascul Pharmacol. 2018 Nov; 110: 7-15.
Sunyecz IL, McCallinhart PE, Patel KU, McDermott MR, Trask AJ. Defining Coronary Flow Patterns: Comprehensive Automation of Transthoracic Doppler Coronary Blood Flow. Sci Rep. 2018 Nov 22; 8: 17268.
McCallinhart PE, Sunyecz IL, Trask AJ. Coronary Microvascular Remodeling in Type 2 Diabetes: Synonymous With Early Aging? Front Physiol. 2018; 9: 1463.

Biography

Academic and Clinical Areas

Center for Cardiovascular Research

Principal Investigator

Academic and Clinical Areas

Center for Cardiovascular Research

Principal Investigator

Academic and Clinical Areas

Center for Cardiovascular Research

Principal Investigator

Center for Cardiovascular Research

Principal Investigator

Center for Cardiovascular Research
Principal Investigator

Awards, Honors & Organizations

Joint Meeting Award, APS-TPS, Dublin, Ireland, 2016
Junior Faculty Citizenship Award, Department of Pediatrics, The Ohio State University College of Medicine, 2015
Elected Fellow (Barbara J. Alexander, PhD, FAHA, Nominator), American Heart Association Council for High Blood Pressure Research, 2014
Invitee/Participant, American Heart Association Scientific Meetings Summit, 2014
Research Recognition Award, Cardiovascular Section, American Physiological Society, 2012
Best Poster Award – Postdoctoral Fellow Category, The Research Institute at Nationwide Children’s Hospital Research Day, 2012
Caroline tum Suden/Frances A. Hellebrandt Professional Opportunity Award, American Physiological Society, 2010
Logo Design Award Winner, American Physiological Society, 2010
Sundberg Memorial Award, WFU Department of Physiology & Pharmacology, 2009
Who’s Who Among Executives and Professionals, Marquis, 2009
Merck New Investigator Award, American Heart Association Council for High Blood Pressure Research, 2008
Hypertension Summer School Travel Award, American Heart Association, 2007
Alumni Travel Award, Wake Forest University Graduate School, 2007
Alumni Travel Award, Wake Forest University Graduate School, 2006
Arts & Sciences Scholarship (2000-2003), Ohio Northern University, 2000
Dean’s Scholarship, Ohio Northern University, 1999
Tiffany Furgason Memorial Scholarship, 1999
Arcanum Alumni Scholarship, 1999
Dean’s List (1999-2003), Ohio Northern University, 1999
Achievement/Leadership Award Scholarship (1999-2003), Ohio Northern University, 1999
Early Career Subcommittee, American Heart Association National Committee on Committees, 2014 - 2015
Member, Microcirculatory Society, 2013 - Present
Faculty Representative, Finance and Sponsored Projects Advisory Group, Nationwide Children’s Hospital, 2013 - Present
Member, American Association for the Advancement of Science, 2011 - Present
Member, American Society for Pharmacology and Experimental Therapeutics Division of Cardiovascular Pharmacology (2009-2012 Public Relations/Communications Committee; 2016-2017: Executive Committee; 2016-2019:, 2009 - Present
Founding Member, Nationwide Children’s Hospital Postdoctoral Association, 2009 - 2013
Student Member, Wake Forest University Department of Physiology and Pharmacology Curriculum Committee, 2006 - Present
Member, American Heart Association Council on Hypertension (2009-2013: Member, Trainee Advocacy Committee; 2013-2016: Chair, Trainee Advocacy Committee; 2013-2016: Member, Leadership Committee; 2015: Programm, 2005 - Present
Member, American Physiological Society (APS), Cardiovascular Section (2009-2012: NIH-NHLBI Liaison Committee; 2012-2015: Awards Committee; 2016-2019: Nominating Committee [Elected]), 2005 - Present
Member, Consortium for Southeastern Hypertension Control, 2005 - Present
Student Member, Wake Forest University Graduate Student Association, 2004 - 2008
Member, Beta Beta Beta National Biology Honor Society, 2001 - Present
Member, Omicron Delta Kappa National Leadership Honor Society, 2001 - Present
Chairman, Judicial Board, Ohio Northern University, 2001 - 2003
Chairman, Judicial Committee, Ohio Northern University Student Senate, 2000 - 2003

Professional Experience

2016 - Present Graduate Faculty, Biomedical Engineering Graduate Program, The Ohio State University, Member

Contact Information

Call us at: (614)355-5760

Fax us at: (614)355-5725

                    Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Contact Information

Call us at: (614)355-5760

Fax us at: (614)355-5725

                    Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Contact Information

Call us at: (614)355-5760

Fax us at: (614)355-5725

                    Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Call us at: (614)355-5760

Fax us at: (614)355-5725

                    Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Call us at: (614)355-5760

Fax us at: (614)355-5725

                    Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Call us at: (614)355-5760

Fax us at: (614)355-5725

                    Abigail Wexner Research InstituteWB4135, 700 Children's Dr Columbus,  43205 (map)

Contact Information#

Contact Information